研究人员表示，这一大模型工具"可使医生提前判断患者健康状况是否会恶化，从而尽早干预"，并能预 测药物副作用，帮助医生根据每位患者的独特特征定制治疗方案，改善治疗效果。这项技术为从被动医 疗转向预测性和个性化医疗铺平了道路，可能为临床试验领域带来颠覆性影响。 相关研究结果已发表于英国《自然合作期刊-数字医学》杂志。（完） 研究团队使用3组涵盖数千份患者电子健康记录的数据集，对现有的大型语言模型进行了训练。这款名 为"数字孪生-生成式预训练变换器"（DT-GPT）的AI模型对阿尔茨海默病、非小细胞肺癌患者，以及重 症监护病房患者的医疗数据进行了分析。 该模型可生成患者的"数字孪生体"，并结合医学文献知识，对患者的病史、实验室化验结果、诊断和治 疗方案等进行综合分析。检验结果显示，DT-GPT能够准确预测患者的健康状况变化，且准确性优于其 他14种最先进的机器学习模型。例如，研究人员为3.5万多名重症监护病房的患者创建了"数字孪生 体"，并依据前一天的实验室化验结果，准确地预测了他们在24小时内的镁水平、血氧饱和度及呼吸频 率的变化。 新华社墨尔本11月18日电（记者徐海静）澳大利亚墨尔本大学日前发布公报说，该校参 ...

Core Insights - The "Bay Area Eye" is a new cultural landmark in Shenzhen, symbolizing a shift from speed-focused construction to a more intelligent and quality-driven approach in urban development [1][6]. Project Overview - The "Bay Area Eye" covers an area of 66,000 square meters with a total construction area of 131,000 square meters, making it one of the largest bookstores globally and a cultural landmark in Bao'an District [2][3]. - The design concept is inspired by "Heaven and Earth," featuring two circular structures that represent the bookstore and a folk museum, complemented by square buildings [3]. Construction Challenges - The project faced significant complexity due to its large scale and unique architectural features, including numerous curved and large-span structures [3][5]. - The construction team utilized Building Information Modeling (BIM) technology to create a digital twin of the building, allowing for early detection of conflicts and optimization of various systems [4][7]. Technological Innovations - BIM technology enabled the integration of all professional drawings and data, facilitating a "one model to the end" approach, which minimized rework and waste during construction [4]. - A custom intelligent scaffolding software was developed to optimize the arrangement of scaffolding, resulting in a 25% reduction in material usage and increased efficiency [4]. Structural Integrity - The project utilized over 11,000 tons of steel, with significant challenges in connecting the two main areas through a large corridor [5][6]. - A closed-loop workflow involving simulation, measurement, and correction was employed to ensure precision in the construction of complex curved shapes [6]. Future Implications - The data from the "Bay Area Eye" will contribute to a City Information Model (CIM), supporting future smart city initiatives in Shenzhen [7]. - The project reflects a broader trend in Shenzhen, where BIM technology has become a standard in large public buildings and infrastructure projects [7].

Core Insights - The article discusses the evolution of the concept of "flow" from Mihaly Csikszentmihalyi's original work to the modern context, emphasizing the challenges posed by digital distractions in achieving flow experiences [1][2] - It highlights the shift in human attention from the physical world to the digital realm, which has fundamentally altered various aspects of life, including thinking, communication, and social interactions [2][3] - The emergence of artificial intelligence and its potential impact on human experiences and flow is explored, suggesting that while AI can enhance productivity, it may also diminish the sense of control necessary for achieving flow [4][5][6] Digital Distractions and Flow - The article illustrates how digital media can fragment attention, making it easier to become distracted rather than engaged in meaningful flow experiences [3][8] - It notes that while digital environments can provide instant gratification, they often lack the depth and challenge required for true flow, leading to a preference for "micro-flow" experiences over more fulfilling "macro-flow" experiences [8][9] Social Interactions and Well-being - Data from the American Time Use Survey indicates a significant decline in face-to-face social interactions among adults and teenagers, attributed to the rise of the internet and digital devices [7] - Research from Harvard University emphasizes the importance of high-quality interpersonal relationships for sustained happiness, suggesting that digital interactions cannot fully replace in-person connections [7] Future of Flow in a Digital Age - The article discusses the potential for AI to create digital twins that could perform tasks on behalf of individuals, which may lead to a loss of personal agency and the ability to experience flow [6][5] - It advocates for finding a balance between digital and physical interactions, encouraging individuals to consciously allocate time for real-world socialization to foster meaningful relationships [7] Characteristics of Flow - To achieve "macro-flow," individuals need clear goals, immediate feedback, and a balance between challenge and skill level, which are often lacking in digital environments [10][13][16] - The article contrasts "micro-flow," characterized by low complexity and immediate gratification, with "macro-flow," which involves deeper engagement and personal growth [9][10][16] Embracing Boredom for Flow - The authors suggest that embracing moments of boredom can lead to greater self-reflection and the potential for personal growth, as these moments allow for the exploration of future goals [17][19] - It emphasizes the importance of self-discipline in resisting the urge to fill every moment with digital distractions, thereby creating space for deeper thought and flow experiences [18][19]