香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其 準確性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部份內容 而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 Asymchem Laboratories (Tianjin) Co., Ltd. 凱萊英醫藥集團（天津）股份有限公司 茲載列本公司在深圳證券交易所網站刊登的以下資料中文全文，僅供參閱。 承董事會命 凱萊英醫藥集團（天津）股份有限公司 Hao Hong博士 董事長、執行董事兼首席執行官 中國天津，二零二五年八月二十五日 （於中華人民共和國註冊成立的股份有限公司） 於本公告日期，本公司董事會由董事長兼執行董事 Hao Hong 博士，執行董事楊蕊女 士、張達先生及洪亮先生，非執行董事 Ye Song 博士及張婷女士，以及獨立非執行董 事孫雪嬌博士、侯欣一博士及謝維愷先生組成。 （股份代號：6821） 海外監管公告 本海外監管公告乃由本公司根據香港聯合交易所有限公司證券上市規則第 13.10B 條作 出。 凯莱英医药集团（天津）股份有限公司 2025 年半年度报告摘要 2025 年半年度报告摘要 1 凯莱英 ...

Core Viewpoint - The company has demonstrated significant revenue growth and has raised its full-year revenue guidance, reflecting confidence in the industry and its own future development [1][2]. Group 1: Financial Performance - In the first half of 2025, the company achieved revenue of 2.7 billion yuan, a year-on-year increase of 62.2%, and a net profit attributable to shareholders of 750 million yuan, up 52.7% year-on-year [1]. - The company's gross margin reached 36.1% in the first half of 2025, an increase of 4.0 percentage points year-on-year, driven by improved capacity utilization and operational efficiency [2]. Group 2: Market Position and Orders - The company's global market share is expected to rise to 22.2% by the first half of 2025, supported by a backlog of unfulfilled orders amounting to 1.33 billion USD, which is a 57.9% increase year-on-year [1]. - The company signed 37 new iCMC projects in the first half of 2025, setting a historical record, with new order amounts increasing by 48.4% year-on-year [1]. Group 3: Capital Expenditure and Growth Strategy - The company plans to increase long-term capital expenditures, with cumulative capital spending expected to exceed 7 billion yuan by 2029, focusing on expanding domestic and international production capacity [2]. - The company is actively developing new ADC and XDC businesses, completing over 2,300 early-stage research projects in the first half of 2025, with a significant portion focused on differentiated targets and new indications [2]. Group 4: Earnings Forecast and Valuation - The earnings per share forecasts for 2025-2027 have been adjusted to 1.29, 1.78, and 2.45 yuan, respectively, reflecting the company's strong growth potential as a leader in the global ADC CRDMO market [3]. - A target price of 65.82 HKD has been set using the DCF valuation method, maintaining a "buy" rating based on the company's long-term development potential [3].

Group 1 - The company reported a revenue of 2.701 billion yuan in H1 2025, representing a year-on-year increase of 62.2%, and an adjusted net profit (excluding interest income and expenses) of 733 million yuan, up 69.6% [1] - The total amount of uncompleted orders reached 1.329 billion yuan, a year-on-year increase of 57.9%, with North America accounting for over half of this total [1] - The company signed 37 new iCMC projects and won 13 iCMC projects in H1 2025, with a total of 563 clients, reflecting a 64% increase [1] Group 2 - The company plans to invest 1.56 billion yuan in capital expenditures in 2025, with total capital expenditures expected to exceed 7 billion yuan by 2029 to expand domestic and international production capacity [2] - The new production facility in Wuxi is fully operational, and the new park is expected to be operational by May 2025, with sufficient order reserves [2] - The company expects Non-GAAP net profits of 1.696 billion yuan, 2.199 billion yuan, and 2.908 billion yuan for 2025, 2026, and 2027 respectively, with corresponding PE ratios of 41, 32, and 24 times [3]

2025年8月22日，康龙化成披露接待调研公告，公司于8月22日接待摩根士丹利、高盛证券、中金证券、 中信证券、招商证券等30家机构调研。 公告显示，康龙化成参与本次接待的人员共1人，为首席财务官、董事会秘书李承宗。调研接待地点为 公司会议室。 据了解，康龙化成管理层对2025年半年度报告进行分析解读。上半年公司实现收入64.41亿元，同比增 长14.9%，归母净利润受上年股权处置收益影响同比下降37.0%，经调整的非《国际财务报告准则》下 归母净利润同比增长9.5%，新签订单同比增长超10%。来自MNC（Top20大药企）客户收入强劲增长 48.0%，现金流良好，新增客户超480家，活跃客户超2600家。公司推进长期战略，全球布局21个研发 中心和生产基地，人才储备充足，各板块项目丰富，还加强数智化投入。各业务板块中，实验室服务、 CMC服务、临床研究服务营收均有增长，大分子和细胞与基因治疗服务营收微增。 第一部分:公司管理层对2025年半年度报告进行分析解读。 2025年上半年,公司实现收入64.41亿元,同比增长14.9%。实现归母净利润为7.01亿元,同比下降37.0%,主 要由于上年同期处置 PRO ...

智通财经 APP 获悉，作为生物偶联药物 CRDMO 领域龙头公司，药明合联(02268)于 8 月 18 日晚间发布了 2025年上半年业绩公告，再度以领跑行业的亮眼 业绩惊艳市场，2025年上半年，公司收入增长62.2%，远超全年增速指引。2022年上半年至2025年上半年，公司收入的年复合增长率(CAGR)高达98%。经过 多年的高速增长，公司市占率自2022年以来持续大幅攀升，2025年上半年达到约22%。这一系列惊人的数字不仅彰显了生物偶联药赛道持续强劲的发展动 能，更充分印证了药明合联在行业内的标杆地位不可撼动，引领势能锐不可挡。 01 药明合联上半年收入利润增幅引航CXO行业 药明合联的业绩表现堪称典范，向市场交出了一份"满分"答卷：公司2025年上半年营业收入达27.01亿元，同比增长62.2%，其中非ADC板块的业务收入更是 实现近翻倍增长；毛利润达9.75亿元，同比增长82.2%；毛利率攀升至36.1%，较2024年全年提升5.5个百分点；更能反应公司实际经营指标的剔除利息收支 后经调整净利润达7.33亿元，同比增长69.6%。各项核心指标均保持强劲增长态势，是ADC CRDMO领域当之无 ...

Investment Rating - The investment rating for the company is "Buy" [3][6]. Core Insights - The company has demonstrated rapid growth in performance, with a significant increase in revenue and net profit for the first half of 2025. Revenue reached 20.799 billion yuan, a year-on-year increase of 20.64%, while net profit attributable to shareholders grew by 101.92% to 8.561 billion yuan [1][2]. - The company's order backlog remains strong, with a total of 56.69 billion yuan in orders as of June 2025, reflecting a year-on-year growth of 37.2%, which supports future revenue growth [2]. - The TIDES business segment has shown exceptional performance, achieving revenue of 5.03 billion yuan in the first half of 2025, a remarkable year-on-year increase of 141.6% [5]. - The chemical drug D&M business has also recovered well, with revenue of 8.68 billion yuan, marking a year-on-year growth of 17.5% [5]. Financial Summary - The company adjusted its revenue forecasts for 2025-2027, with expected revenues of 44.331 billion yuan, 51.087 billion yuan, and 59.245 billion yuan respectively, reflecting a positive outlook [3][8]. - The earnings per share (EPS) estimates for 2025-2027 have been revised to 5.12 yuan, 5.27 yuan, and 6.21 yuan respectively, indicating strong growth potential [3][8]. - The company's gross margin is projected to improve, reaching 44.9% in 2025 and increasing to 46.3% by 2027 [8]. Business Segments - The TIDES business continues to be a key driver of performance, with a 48.8% year-on-year increase in the order backlog as of June 2025, and an increase in the number of clients served [5]. - The chemical drug D&M segment has added 412 new molecules to its pipeline in the first half of 2025, including four projects in Phase III and four commercial projects, indicating a growing demand [5]. Market Position - The company's total market capitalization is approximately 283.919 billion yuan, with a free float market capitalization of the same amount [3]. - The stock has shown a 52-week high of 102.49 yuan and a low of 36.86 yuan, indicating significant volatility and potential for growth [3].

Core Viewpoint - Citigroup reports that WuXi AppTec's management has raised its 2025 guidance primarily due to rapid capacity expansion rather than a surge in orders prior to the tariff war [1] Group 1: Revenue Guidance - Management expects that the revenue from continuing operations in the second half of 2025 will achieve double-digit growth both year-on-year and compared to the first half [1] - The new guidance indicates a year-on-year growth of 5% to 10% and a growth of 6% to 11% compared to the first half of 2025 [1] Group 2: Earnings Forecast - Citigroup did not significantly raise its revenue forecast for WuXi AppTec, as expectations were already adjusted following the first-quarter earnings announcement [1] - The bank has increased its earnings per share forecasts for WuXi AppTec for 2025 to 2027 by 3%, 6%, and 7% respectively, driven by margin expansion in the chemical business, a decrease in administrative expense ratios, and higher investment income [1] Group 3: Target Price Adjustment - Due to a more optimistic earnings outlook, Citigroup has raised the target price for WuXi AppTec's H-shares from HKD 95 to HKD 130 and for A-shares from CNY 88 to CNY 119 [1] - WuXi AppTec is now listed as a preferred stock in the Contract Development and Manufacturing Organization (CDMO) sector with a "Buy" rating [1]

Summary of WuXi AppTec's Conference Call Company Overview - **Company**: WuXi AppTec - **Date**: July 29, 2025 Key Financial Performance - **Net Profit**: Reached 6.31 billion RMB in H1 2025, a year-on-year increase of 44.4% [2][3] - **Total Revenue**: Achieved 20.6% growth, totaling 20.8 billion RMB [3] - **Backlog Orders**: Increased to 56.69 billion RMB, up 30% year-on-year [4] - **Revenue Guidance**: Full-year revenue guidance raised to 13%-17%, expecting total revenue of 42.5-43.5 billion RMB [5][16] Regional Performance - **Global Market**: Strong performance with U.S. revenue up 38.4%, Europe up 9.2%, while China saw a decline [2][6] - **Diverse Revenue Sources**: Enhanced stability and resilience in performance due to diversified income streams [6] Business Segment Highlights - **Chemistry and DRDMO**: Revenue grew 33.5% to 16.3 billion RMB, with a gross margin increase to 49% [2][8] - **TIDES Business**: Revenue surged 141.6% to 5.03 billion RMB, with backlog orders up 48.8% [2][10] - **Small Molecule CDMO**: Revenue increased 17.5% to 8.68 billion RMB, with capacity expected to exceed 4 million liters by year-end [2][9] - **Laboratory Analysis and Testing**: Slight revenue decline to 2.69 billion RMB, but drug safety evaluation business grew [12] - **Clinical CRO and SMO**: Revenue decreased 4.7% to 800 million RMB, with SMO maintaining industry leadership [13] Sustainability Achievements - **MSCI Rating**: Achieved highest Triple A rating, first in A-share life sciences sector [7] Shareholder Returns - **Dividends**: Completed cash dividends of 3.84 billion RMB and initiated a new round of A-share buybacks [5][17] - **Stock Buybacks**: 1 billion RMB buyback plan approved [17][29] Future Outlook - **Growth Strategy**: Focus on CRDMO business model and global DNM capacity expansion [16] - **Market Trends**: Anticipated strong demand for GLP-1 drugs, with significant growth potential in peptide and small molecule drugs [21][22] Operational Insights - **Production Efficiency**: Improved production processes leading to higher gross margins, particularly in Chemistry [22] - **Inventory Growth**: Increased inventory by over 30% to support rising order demands [30] Industry Context - **BD Transactions**: Active domestic innovation drug BD transactions enhancing industry sentiment [27] - **Market Dynamics**: Stable pricing trends observed in the market, with a focus on high-quality clients [27] This summary encapsulates the key points from WuXi AppTec's conference call, highlighting financial performance, business segment growth, sustainability efforts, shareholder returns, and future outlook.

Core Insights - WuXi AppTec (02359) reported an unaudited interim performance for the six months ending June 30, 2025, with revenue of 20.799 billion RMB, a year-on-year increase of 20.6% [1] - The gross profit reached 9.112 billion RMB, up 36% year-on-year, while the net profit attributable to shareholders was 8.287 billion RMB, reflecting a significant increase of 95.5% [1] - The company proposed an interim dividend of 3.5 RMB per 10 shares [1] Revenue Breakdown - The company’s revenue from ongoing operations was 20.41 billion RMB, with significant contributions from various regions: 14.03 billion RMB from U.S. clients (up 38.4%), 2.33 billion RMB from European clients (up 9.2%), 3.15 billion RMB from Chinese clients (down 5.2%), and 0.9 billion RMB from other regions (up 7.6%) [1] Chemical Business Performance - The chemical business generated revenue of 16.3 billion RMB, marking a year-on-year growth of 33.5% [2] - The small molecule drug discovery segment successfully synthesized and delivered over 440,000 new compounds in the past twelve months [2] - The small molecule development and manufacturing (D&M) segment reported revenue of 8.68 billion RMB, a 17.5% increase year-on-year, with a total of 3,409 molecules in the pipeline as of June 30, 2025 [2] TIDES Business Growth - The TIDES business (oligonucleotides and peptides) experienced rapid growth, with revenue reaching 5.03 billion RMB, a remarkable increase of 141.6% [3] - The backlog of TIDES orders grew by 48.8% year-on-year, with a 12% increase in the number of clients served and a 16% increase in the number of molecules served [3] - The company is expanding its peptide production capacity, expecting the total volume of solid-phase synthesis reactors to exceed 100,000L by the end of 2025 [3]

Core Viewpoint - WuXi AppTec expects its overall revenue for 2025 to be adjusted upwards from RMB 415-430 billion to RMB 425-435 billion, indicating a positive outlook for the company's financial performance [1] Revenue Growth - The company anticipates a return to double-digit growth in its continuing operations, with the growth rate revised from 10-15% to 13-17% for 2025 [1] Business Focus - WuXi AppTec will continue to focus on its CRDMO core business and aims to enhance production and operational efficiency [1] Shareholder Returns - In an effort to increase shareholder returns, the company has declared a special dividend of approximately RMB 1 billion, which was completed in May 2025 [1] - The board has approved a mid-year profit distribution plan for 2025, proposing a total cash dividend of around RMB 1 billion [1]