近日，湖北仙桃市主要领导深入毛嘴镇、郑场镇、三伏潭镇及仙桃高新区等地，就重点项目推进与产业 发展工作展开调研。调研强调，要立足资源禀赋，培育壮大特色主导产业，以高质量项目建设为引擎， 为仙桃经济社会发展注入强劲动力。 激活镇域经济打造产业名片 在毛嘴镇，调研团队首先考察了服装博物馆及奕久服饰有限公司。毛嘴镇服装博物馆定位"溯源产业脉 络、彰显品牌价值"，已搭建起创意创新与信息发布的多功能平台。领导要求进一步优化布局，将其打 造成为当地服装产业的展示窗口与创新载体。 奕久服饰作为亚马逊平台核心供应商，其产销模式创新获得肯定。调研指出，企业要持续"增品种、提 品质、创品牌"，积极拓展国内外市场，为镇域经济发展树立标杆。 随后，调研团队前往引隆补水工程试验段施工现场。该工程作为重要民生项目，建成后将有效改善区域 水资源配置。调研要求相关部门与施工方密切协作，发扬拼搏精神，确保工程成为精品工程、德政工 程，早日惠及百姓。 攻坚高新产业夯实发展支撑 在仙桃高新区，调研强调，作为全市高质量发展的重要增长极，高新区需以"紧起来、动起来、跑起 来"的姿态，推动项目建设提速提质提效，为全市经济目标提供坚实支撑。 位于三伏潭镇的 ...

10月10日，迈威生物跌5.07%，截至发稿，报44.98元/股，成交3.57亿元，换手率3.77%，总市值179.74 亿元。 平安瑞尚六个月持有混合A（010239）基金经理为唐煜。 截至发稿，唐煜累计任职时间5年213天，现任基金资产总规模81.35亿元，任职期间最佳基金回报 22.55%， 任职期间最差基金回报-10.22%。 从基金十大重仓股角度 数据显示，平安基金旗下1只基金重仓迈威生物。平安瑞尚六个月持有混合A（010239）二季度持有股 数4.92万股，占基金净值比例为0.67%，位居第七大重仓股。根据测算，今日浮亏损失约11.81万元。 平安瑞尚六个月持有混合A（010239）成立日期2020年12月18日，最新规模1.45亿。今年以来收益 10.87%，同类排名5923/8166；近一年收益12.42%，同类排名5641/8014；成立以来收益15.67%。 风险提示：市场有风险，投资需谨慎。本文为AI大模型自动发布，任何在本文出现的信息（包括但不 限于个股、评论、预测、图表、指标、理论、任何形式的表述等）均只作为参考，不构成个人投资建 议。 资料显示，迈威(上海)生物科技股份有限公司位于 ...

天眼查App显示，近日，广州欧莱缤生物科技有限公司成立，注册资本10万人民币，经营范围为体育用 品及器材零售;日用百货销售;日用品销售;体育用品及器材批发;玩具销售;电子产品销售;家居用品销售;网 络技术服务;技术服务、技术开发、技术咨询、技术交流、技术转让、技术推广;包装服务;互联网销售 （除销售需要许可的商品）;中医养生保健服务（非医疗）;保健食品（预包装）销售;食品互联网销售 （仅销售预包装食品）;农产品的生产、销售、加工、运输、贮藏及其他相关服务;食品销售（仅销售预 包装食品）;养生保健服务（非医疗）;食用农产品初加工;化妆品零售;化妆品批发;信息技术咨询服务;健 康咨询服务（不含诊疗服务）;生物质能技术服务。 ...

Core Viewpoint - Recent stock transfer activities and refinancing arrangements indicate significant financial maneuvers by the company, reflecting its strategic focus on capital management and operational funding [1] Group 1: Stock Transfer Activities - On October 9, shareholders of 信铭生命科技 (00474) transferred shares from Haitong International Securities to Imagi Brokerage Limited, with a transfer value of HKD 124 million, accounting for 26.56% of the total [1] - On October 8, another transfer occurred, moving shares valued at HKD 67.98 million from Haitong International Securities to Imagi Brokerage Limited, representing 13.95% of the total [1] Group 2: Refinancing Arrangements - The company announced a refinancing arrangement related to a 2018 financing agreement, with all conditions for the 2025 loan agreement met and completed on September 26, 2025 [1] - The total financing provided amounts to approximately GBP 87.3 million, of which about GBP 70.3 million has been withdrawn to fully repay UK loans and associated transaction costs [1] - The remaining GBP 17 million is earmarked for capital expenditures on UK properties over the next one to two years [1]

Group 1 - The core point of the article highlights significant shareholder activity in Ximing Life Technology, with a total of HKD 1.24 billion worth of shares transferred to lmagi Brokerage Limited on October 9, representing 26.56% of the company's shares [1] - On October 8, another transfer occurred, with shares worth HKD 67.98 million moved from Haitong International Securities to lmagi Brokerage Limited, accounting for 13.95% of the shares [1] - The company announced a refinancing arrangement related to a 2018 financing agreement, with all conditions for a loan agreement due in 2025 met and completed on September 26, 2025 [1] Group 2 - Following the completion of the refinancing, the company secured a total financing amount of approximately GBP 87.3 million, with GBP 70.3 million withdrawn for repaying UK loans and associated transaction costs [1] - The remaining GBP 17 million is earmarked for capital expenditures on UK properties over the next one to two years [1]

2 0 2 5年9月2 9日，北京市科学技术 委员会、中关 村科技园区管理委员会联合发布通知， 以"揭榜挂帅"方式向社会公开征集2 0 2 5年 度生物样本库建设技术攻关项目 。 此次发布的榜单涵盖 基因测序平台、蛋白质组学检测平台以及人工智能随访系统 三大方向，旨 在推动生物样本库建设，提升生物医药领域的创新能力和核心竞争力。 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 一、基因测序平台 基因测序平台的建设目标是建立高通量基因测序平台，实现从样本到数据的全流程自动化。该平台需具备以下关键指标： 自动化水平：全流程自动化，包括自动样本前处理和文库建库系统。 通量要求：测序读长不低于1 5 0 b p，兼容靶向测序、全基因组测序及全基因组甲基化测序。 数据质量：人全基因组测序有效测序平均深度为3 0 - 3 5X，PE1 5 0平均测序质量Q3 0≥8 5%，基因组比对率≥9 9%。 生信分析能力：日处理能力不少于1 2 0人份全基因组测序数据。 成本控制：以5万例样本为测算依据，探索单样本基因测序极限成本。 考核指标包括建立完整的基因测 ...

Core Viewpoint - The Hong Kong stock market experienced a decline, with the Hang Seng Index falling by 0.29% and the Hang Seng Tech Index decreasing by 0.66% [1] Market Performance - The Hong Kong stock market closed with the Hang Seng Index down by 0.29% and the Hang Seng Tech Index down by 0.66% [1] - The Hong Kong Technology ETF (159751) decreased by 0.08%, while the Hang Seng Hong Kong Stock Connect ETF (159318) fell by 0.41% [1] Sector Performance - Passenger airlines and the metals and mining sectors showed positive performance, while the biotechnology and pharmaceutical sectors faced declines [1] Individual Stock Movements - Notable gainers included: - Hang Seng Bank up by 25.88% - ZTE Corporation up by 12.4% - China Railway up by 10.08% - Jiangxi Copper up by 8.18% - Luoyang Molybdenum up by 7.86% - Lenovo Group up by 7.26% - Mixue Group up by 6.99% - China Aluminum up by 5.48% - Zijin Mining up by 5.43% - CRRC Corporation up by 5.17% - China General Nuclear Power up by 4.76% - ZTO Express up by 4.2% - China Coal Energy up by 4.15% [1] - Significant decliners included: - Crystal International Holdings down by 13.91% - Shandong Hi-Speed down by 19.7% - Shanghai Electric up by 17.4% [1]

Core Viewpoint - The Hong Kong stock market showed mixed performance with the Hang Seng Index rising by 0.04% and the Hang Seng Tech Index increasing by 0.63% [1] Sector Performance - The passenger airline and metals & mining sectors experienced notable gains, while the biotechnology and pharmaceutical sectors faced significant declines [1] Individual Stock Movements - Notable gainers included: - Hang Seng Bank up by 26.3% - Jiangxi Copper (600362) up by 11.19% - ZTE Corporation (000063) up by 10.73% - China Railway (601390) up by 9.04% - Mixue Group up by 8.96% - Luoyang Molybdenum (603993) up by 8.04% - Hua Hong Semiconductor up by 6.75% - Lenovo Group up by 6.41% - Zijin Mining up by 5.48% - China General Nuclear Power (601766) up by 5.44% - China CRRC (601766) up by 4.17% [1] - Significant decliners included: - Innovent Biologics down by 9.68% - Shandong Hi-Speed down by 12.55% [1] - Shanghai Electric (601727) saw a substantial increase of 15.72% [1]

Group 1 - The Hang Seng Index rose by 0.04%, gaining 11 points to close at 26,840 points, while the Hang Seng Tech Index increased by 0.63% [1] - Shanghai Electric (601727) surged by 15.72%, hitting the upper limit in A-shares, driven by recent positive developments in the controllable nuclear fusion sector [1] - Hua Hong Semiconductor (01347) climbed 6.75%, reaching a new high as local supply chain integration accelerates, with domestic foundry demand expected to expand rapidly [1] - Jiangxi Copper (600362) shares rose by 11%, as the company is a leading copper smelter in China, with First Quantum's copper mine expected to resume production [1] - Luoyang Molybdenum (603993) increased by 8%, following a significant rise in cobalt prices, which surged over 11% in the previous two days due to strict export controls from the Congo [1] Group 2 - Hang Seng Bank (00011) saw a 26% increase, following HSBC's recommendation for its privatization [2] - Solar energy stocks experienced gains, with upstream prices rising more than downstream prices in September; New Special Energy (01799) rose 4.52%, Flat Glass (601865) increased by 7.67%, and GCL-Poly Energy (03800) gained 3.73% [2] - High-speed rail infrastructure stocks led the gains, with record railway investment progress; China Railway (601390) rose 9%, China Metallurgical Group (601618) increased by 6%, and CRRC Corporation (601766) gained 4.17% [2] - ZTE Corporation (00763) saw both A and H shares rise, with the launch of Co-Sight super intelligent system indicating positive growth potential in the enterprise AI market; H shares increased by 10.73% [2] Group 3 - Mixue Group (02097) rose 8.96% despite market trends, as it made a forward-looking investment in fresh beer brand Fulu, expanding its "tea + coffee + fresh beer" portfolio [3] - The Hang Seng Biotechnology Index fell by 3.52%, with notable declines in stocks such as Innovent Biologics (09969) down over 9%, I-Mab (01801) down over 6%, and China Biologic Products (01177) down over 6% [3] Group 4 - Smoore International (06969) dropped over 9%, having fallen more than 30% from its year-to-date high, with UBS projecting lower earnings than market consensus [4]

撰文丨王聪 编辑丨王多鱼 排版丨水成文 酶 （ Enzyme ） 是生命的分子机器，其功能的一个关键特性是底物特异性——即酶能够识别并选择性地作用于特定底物的能力。这种特异性源自酶活性位点的三 维 （3D） 结构以及反应复杂的过渡态。实际上，许多酶并非传统认为的那样"专一"，它们可能具有多功能性，除了作用于其最初进化时涉及的底物，还能作用 于其他结构相似的底物，从而催化不同类型的反应。 此外，数以百万计的 已知的酶仍缺乏可靠的底物特异性信息，这阻碍了它们的实际应用以及我们对自然界生物催化多样性的全面理解。 2025 年 10 月 8 日， 伊利诺伊大学厄巴纳-香槟分校 （UIUC） 赵惠民 教授团队 （ 崔海洋 、 苏雨峰 为共同第一作者 ） 在国际顶尖学术期刊 Nature 上发表 了 题为： Enzyme specificity prediction using cross attention graph neural networks 的研究论文，论文第一作者 崔海洋 博士现为 南京师范大学教授。 该研究提出了一种结合 跨注意力机制 （Cross-Attention） 与 SE(3)-等变图神经网络 （ ...