□ 本报记者李凯通讯员麒轩 暑假期间，各大医院里来矫治脊柱侧弯的孩子明显增加。国家疾控中心、国家儿童青少年脊柱侧弯防控 工作组等机构的研究数据显示，脊柱侧弯已成为我国中小学生继肥胖、近视后的第三大健康杀手，发生 率为1%—3%。 一方面是呈逐年上升趋势的发病率，另一方面是传统诊疗体系的短板和痛点——专业筛查资源少导致等 待周期长、缺乏专用3D打印设备、定制化矫形支具动辄上万元的费用更让许多家庭望而却步。面对这 一现实困境，南京麒麟科创园一家新成立的科技企业——南京云兮生物科技有限公司正用AI技术构建 全新解决方案，为青少年足脊矫正带来开创性新产品。 "脊柱侧弯，一个看似不起眼却可能影响孩子一生的健康隐患。最新的人工智能技术和新材料有望解决 这个难题，但目前市面上还缺乏这样的破局者，而这也是团队创业的出发点。"云兮生物运营总监邵漠 宇介绍。 "既提升个性化定制的设计制造效率，又提高矫正精准度。"邵漠宇表示，"矫形器本身也做了智能化开 发，相比传统的矫形器，我们的矫形器适配后可以智能感知力学矫正状况及患者的呼吸波、心率等生理 指标，实现力学矫正状况的实时监测，这样患者有没有按时佩戴、佩戴是否规范，我们和家长都可以 ...

Core Insights - The article emphasizes the importance of integrating clinical, capital, channel, and regulatory aspects to drive high-quality development in the medical technology sector, particularly focusing on Chinese innovation in the global context [1]. Group 1: Medical Ecosystem and Innovation - The Shanghai Jiao Tong University School of Medicine is highlighted as a key player in fostering a valuable medical and health ecosystem, with 13 affiliated hospitals and 21 academicians providing strong academic support and clinical resources for entrepreneurs [9]. - The establishment of the first incubation fund by the Medical Future Alumni Association aims to lead alumni in early investments in medical technology, facilitating earlier market entry [9]. - The article discusses the unique "Value Engine Methodology" that promotes collaboration between academia and industry, enhancing strategic thinking, innovation capabilities, and leadership skills among entrepreneurs [9][10]. Group 2: Educational Programs and Curriculum - The curriculum is designed to address trends, challenges, and innovations in the medical industry, helping participants understand the development trajectory and strategic layout of the sector [11]. - The program emphasizes the cultivation of entrepreneurial thinking, enabling participants to formulate growth strategies and make informed decisions in uncertain market conditions [12]. - Various modules cover topics such as strategic customization, value discovery, and innovative thinking, aimed at equipping participants with the necessary skills for future challenges in the medical field [16]. Group 3: Industry Trends and Future Directions - The article identifies key trends in the medical industry, including the aging economy, consumer healthcare, and the integration of technology in healthcare services [17][19]. - It discusses the importance of understanding the silver economy's value chain, including sectors like elderly care, rehabilitation, and entertainment, as well as the emerging business models in consumer healthcare [19]. - The integration of new technologies such as artificial intelligence, big data, and wearable devices is highlighted as a significant trend shaping the future of the medical industry [19].

Core Insights - The Hubei Province Medical Technology Innovation Achievements Conference highlighted the establishment of the Hubei Brain-Computer Interface Industry Innovation Development Alliance, with Tongji Hospital as the chair unit [1] - Tongji Hospital showcased 46 innovative achievements, including 10 major breakthroughs in fields such as brain-computer interfaces, gene therapy, surgical robots, and smart medical platforms, demonstrating Hubei's strong capabilities in medical technology [1] - A significant achievement was the successful completion of the first implanted brain-computer interface surgery in Central China, marking a key advancement in functional reconstruction for patients [1] Group 1 - The Hubei Brain-Computer Interface Industry Innovation Development Alliance was officially established [1] - Tongji Hospital presented 46 innovative medical technology achievements, many of which are national or global firsts [1] - The conference was broadcasted live on CCTV, showcasing Hubei's medical technology strength to a global audience [1] Group 2 - The hospital's first implanted brain-computer interface surgery was completed in June, allowing a patient to independently drink water one month post-surgery [1] - The hospital is focusing on disruptive innovations in life sciences and health industry, as stated by Professor Tang Zhouping [1] - Various teams at Tongji Hospital are exploring different technical routes for brain-computer interfaces, including non-invasive and semi-invasive methods for treating chronic conditions and improving rehabilitation outcomes [2]

Group 1 - The Fourth Global Digital Trade Expo "Digital Trade Investment Day" was successfully held in Xi'an, focusing on digital trade and technology entrepreneurship projects [1][2] - The event was organized by various government departments and investment institutions from Zhejiang and Shaanxi provinces, with nearly a hundred participants including well-known investment firms and tech companies [1][2][6] - The expo features a rich content structure, including an exhibition area with a theme zone and seven specialty industry zones, as well as 36 key activities [2][6] Group 2 - Shaanxi province, as the guest province, will set up a 210 square meter special exhibition area and invite local enterprises to participate in the expo [6][10] - The event highlighted the advantages of digital trade, emphasizing Shaanxi's rich scientific and educational resources, strong innovation momentum, and significant openness [6][10] - Various investment institutions shared their experiences in supporting local tech enterprises and discussed the growth paths for innovative companies from early-stage support to IPO [14][24] Group 3 - Several tech companies showcased their core technologies and products, including a wireless cardiac pacemaker and AI solutions for industrial quality inspection [27] - The event facilitated on-site matching between venture capital and project parties, leading to preliminary cooperation intentions between multiple investment institutions and tech enterprises [27]

Core Points - The company has completed the cancellation of 13,651 shares from its repurchase account, which accounts for 0.0019% of the total share capital, reducing the total shares from 717,026,333 to 717,012,682 [1][2][3] Summary by Sections Share Repurchase and Cancellation - The company has approved the cancellation of 13,651 shares from its repurchase account, following the necessary approval procedures [1][2] - The total amount allocated for share repurchase was between RMB 80 million and RMB 150 million, with a maximum repurchase price of RMB 12.00 per share [1] Reasons for Cancellation - The cancellation of shares is in accordance with the regulations set by the China Securities Regulatory Commission, which requires shares not used for employee stock ownership plans or equity incentive plans within three years to be canceled [2][3] Changes in Share Capital Structure - After the cancellation, the share capital structure will be as follows: - Restricted shares: 4,965,242 shares (0.69%) - Unrestricted shares: 712,047,440 shares (99.31%) - Total shares after cancellation: 717,012,682 shares [3] Impact of Cancellation - The cancellation of shares complies with relevant regulations and will not materially affect the company's operational performance or financial status, nor will it change the control of the company [3] Future Arrangements - The company will proceed with the necessary changes to its registered capital, amend its articles of association, and complete the relevant business registration and filing [3]

Core Viewpoint - The announcement details the renewal of the "Joint Control Agreement" and the termination of the original "Consistent Action Agreement" for Nanjing Mailland Medical Technology Co., Ltd, involving key shareholders and their shareholding structure [1][2][11] Group 1: Shareholding Changes - After the equity change, the total direct shareholding of the controlling shareholders and actual controllers, Yang Ruijia and Shi Zhihuai, remains unchanged at 60,595,842 shares, representing 60.60% of the total shares [2][11] - The previous total direct shareholding before the new agreement was 63,173,210 shares, which accounted for 63.17% of the total shares [10][11] Group 2: Agreements and Their Implications - The original "Joint Control Agreement" and "Consistent Action Agreement" were set to expire on August 10, 2025, leading to the renewal of the "Joint Control Agreement" and the signing of a new "Consistent Action Agreement" with some shareholders [2][3][11] - The new "Consistent Action Agreement" includes Yang Ruijia, Shi Zhihuai, Chen Bin, Tu Honglin, Wang Wang, and Zhou Qin, while Zhou Gan did not renew his agreement, thus ending his consistent action relationship with the actual controllers [2][3][11] Group 3: Governance and Management Stability - The renewal of these agreements is expected to stabilize the company's control and ensure continuity in development strategies and management policies, without negatively impacting daily operations or harming the interests of minority investors [11]

Core Insights - Tempus AI, Inc. reported a narrower adjusted loss of 22 cents per share for Q2 2025, beating the Zacks Consensus Estimate by 4.35% [1][8] - Revenues reached $314.6 million, exceeding expectations by 5.12% and showing an 89.6% year-over-year increase [2][8] Revenue Breakdown - Genomics segment generated $193.8 million in revenues, a 115.3% increase year-over-year, with oncology testing contributing $133.2 million (up 32.9%) and hereditary testing $97.3 million (up 33.6%) [3][8] - Data and Services product line reported $72.8 million in sales, reflecting a 35.7% year-over-year growth, driven by a 40.7% increase in data licensing [4] Margin Performance - Gross profit for the quarter was $195 million, up 158.3% from the previous year, with an adjusted gross margin of 62%, expanding by 1649 basis points despite a 32.2% rise in costs [5] Liquidity Position - At the end of Q2 2025, the company had cash and cash equivalents of $186.3 million, an increase from $151.6 million at the end of Q1 [6] - Cumulative net cash used in operating activities was $61.46 million, significantly reduced from an outflow of $198.5 million in the prior year [6] Full-Year Outlook - Updated guidance for 2025 projects revenues of approximately $1.26 billion, indicating nearly 82% annual growth, with adjusted EBITDA expected to improve by approximately $110 million over 2024 [7] Stock Performance - Following the earnings announcement, shares of Tempus AI rose by 2.2% in pre-market trading, reflecting positive market sentiment [2][9]

Group 1 - The core viewpoint of the news is that Madi Technology (603990) has experienced a decline in stock price and significant changes in its financial performance as of the first quarter of 2025 [1][3] - As of August 8, 2025, Madi Technology's stock closed at 15.05 yuan, down 1.51%, with a turnover rate of 4.29% and a trading volume of 131,300 hands, amounting to 198 million yuan [1] - The net outflow of main funds today was 33.96 million yuan, accounting for 17.18% of the transaction amount, with large orders showing a net outflow of 20.07 million yuan [1] Group 2 - For the first quarter of 2025, Madi Technology reported total operating revenue of 63.34 million yuan, a year-on-year decrease of 43.13%, while net profit attributable to shareholders was 23.60 million yuan, a year-on-year increase of 138.55% [1] - The company has a current ratio of 2.95, a quick ratio of 2.82, and a debt-to-asset ratio of 34.04% [1] - Madi Technology, established in 2009 and located in Suzhou, focuses on research and experimental development, with a registered capital of 3.06 billion yuan [1][2] Group 3 - Madi Technology has made investments in 9 companies and participated in 3,031 bidding projects, holding 84 trademark registrations and 168 patents [2]

丹尼尔·纳德勒（Daniel Nadler）创办了OpenEvidence，帮医生们从海量医学研究中理出头绪。如今，他已筹得2.1亿美元资金，公司估值达35 亿美元。 图片来源：Mauricio Candela for Forbes 原文标题：《这位AI创始人靠打造医生专用的"ChatGPT"成为亿万富豪》 对医生而言，要想紧跟最新医学突破的脚步，就得啃下层出不穷的研究成果，这感觉简直就像经受高压水炮迎面轰击。每30秒就有一篇新论文发表，医生 们在每天接诊20个病人之余，还要从新研究成果中筛选信息制定最佳诊疗方案，简直难如登天。 "都说现在是生物技术的黄金时代，新药、好药不断涌现。但对医生来说，这简直是黑暗时代，他们都快被压垮了，"OpenEvidence联合创始人兼CEO丹尼 尔·纳德勒告诉《福布斯》，"海量信息像洪流一样涌来，他们必须时刻紧盯前沿动态，可是以人类大脑的局限性，哪能吃得下几百万篇研究呢。" 图片来源：Mauricio Candela for Forbes 于是，42岁的纳德勒——这位哈佛博士曾在2018年以5.5亿美元卖出了自己的上一家公司——决定用人工智能解决问题。他现在的这家初创公司开发 ...

格隆汇8月8日丨麦迪科技(603990.SH)在投资者互动平台表示，目前公司在脑机接口方面尚无直接布 局，公司持续关注该领域前沿进展，特别是其在康复训练、人机交互等医疗康复应用场景中的潜力。 ...