Core Viewpoint - The article discusses the competitive landscape in the functional skincare market, focusing on the rivalry between two prominent female entrepreneurs, Fan Daidi from Xi'an and Yang Xia from Shanxi, as they pivot their companies towards the C-end beauty segment, particularly in the context of the recent Double 11 shopping festival [1][12]. Group 1: Market Dynamics - The Double 11 shopping festival has seen a new brand "Tongpin" rapidly rise in popularity, achieving significant sales growth, with its GMV ranking second in Li Jiaqi's live broadcast [1][5]. - Despite the success of Tongpin, the stock price of Juzhi Biological has been declining, hitting a new low of 40.40 HKD per share, with a total market value of 43.3 billion HKD [2]. - Juzhi Biological's stock has faced continuous declines, while Jinbo Biological's stock also fell, indicating a broader trend of market challenges for both companies [2]. Group 2: Brand Development - Tongpin, established in March 2024, focuses on technology-driven skincare solutions and has launched a limited range of products, including five core items [4]. - The brand's rapid sales growth is attributed to its strategic partnerships with top influencers, particularly in live streaming channels [5]. - During the Double 11 event, Tongpin achieved over 20 million RMB in sales, ranking first among new brands on Tmall [5]. Group 3: Corporate Relationships - Tongpin is closely linked to Jinbo Biological, which provides technical support and has several patented ingredients used in Tongpin's products [7]. - Jinbo Biological's founder, Yang Xia, has actively promoted Tongpin, indicating a strategic shift from B-end medical devices to C-end skincare [1][7]. - Jinbo Biological has recently attracted investment from Zhong Shanshan, founder of Nongfu Spring, further solidifying its market position [12]. Group 4: Industry Implications - The competition between Juzhi Biological and Jinbo Biological reflects a broader trend of blurring lines between pharmaceutical and beauty companies in China's functional skincare market [13]. - The outcome of this rivalry will significantly influence the next industry cycle and determine the leading players in the market [13].

0:00 21世纪经济报道 记者凌晨 一场围绕"重组胶原蛋白"的行业对决，将两位区域女首富与其上市公司推向台前。陕西范代娣领导的巨 子生物曾是赛道标杆，而山西杨霞执掌的锦波生物正通过新品牌"同频"跨界切入C端护肤市场。 战事首先在电商直播间打响。同频在李佳琦直播间快速崛起，今年双十一李佳琦首场直播中GMV增速 位列第二。同时，一向低调的锦波生物创始人杨霞罕见为同频站台，被视为其从B端药械进军C端美妆 的明确信号。 从胶原蛋白药械到美妆，锦波的降维入场，无疑对主攻C端的巨子，形成正面冲击。同样的流量带货手 法、同类型的产品，锦波能否凭借医药背景实现超车，将决定胶原蛋白市场下一阶段的格局走向。 ...

Core Insights - The annual "500 Wealth Creation List" by New Fortune has been released, with Zhang Yiming of ByteDance topping the list for the first time at 481.5 billion yuan, while Zhong Shanshan's wealth has decreased to 360 billion yuan, dropping him to second place after four consecutive years as the richest [1][22]. Company Overview - Zhong Shanshan's business empire has faced significant challenges, with Nongfu Spring's bottled water revenue declining by 21.3%, marking its worst performance since going public, and Wantai Biological's net profit plummeting by 91.5% due to increased competition in the HPV vaccine market [2][22]. - Despite these setbacks, Zhong has actively invested in new ventures, including a 3.4 billion yuan stake in Jinbo Biological, a rising player in the medical beauty sector [2][23]. Industry Dynamics - The medical beauty industry is characterized by the emergence of "female billionaires," with notable figures like Yang Xia, founder of Jinbo Biological, who has a net worth of 11.5 billion yuan [4][6]. - Jinbo Biological, established later than its competitors, has seen its stock price surge by 802% since its listing on the Beijing Stock Exchange in 2023, reaching a market value of over 50 billion yuan [7][11]. - The company has achieved a gross margin of 92.02%, surpassing that of Moutai, despite its revenue being significantly lower than that of its competitors [11][15]. Financial Performance - Jinbo Biological's revenue has grown from 233 million yuan in 2021 to 1.443 billion yuan in 2024, with net profit increasing from 57 million yuan to 732 million yuan during the same period [11][12]. - The company has successfully commercialized its recombinant collagen products, receiving multiple medical device registrations, which has contributed to its competitive edge [11][12]. Market Challenges - The medical beauty sector is currently experiencing intense competition, particularly in the recombinant collagen market, which has seen a decline in the popularity of hyaluronic acid products [12][15]. - Jinbo Biological's marketing expenses have surged by 56.73% in 2025, indicating a strategic shift towards expanding its consumer market presence [15][17]. - The company faces challenges in building brand recognition among consumers, as a significant portion of its revenue is still reliant on medical institutions [15][17]. Strategic Moves - Zhong Shanshan's investment in Jinbo Biological is seen as a strategic move to enhance his business portfolio, particularly in the high-margin collagen market, which is projected to reach a market size of 219.3 billion yuan by 2030 [21][23]. - The partnership with Yang Xia and Jinbo Biological is expected to leverage Zhong's existing distribution networks to strengthen brand presence in the consumer market [21][23].