Core Insights - The 17th China Bio-Industry Conference was held on September 4, 2025, in Wuhan, showcasing the latest innovations in the bio-manufacturing sector [1][3] - The conference highlighted the achievements of Wuhan's Optics Valley Bio-City, which has become a leading hub for biopharmaceuticals in China, housing over 4,200 companies and nurturing 531 high-tech enterprises [3][6] Group 1: Event Highlights - The conference released the "Most Innovative Bio-Manufacturing Base" list, recognizing ten national bio-industry bases, including Wuhan, Shanghai, Beijing, Hangzhou, and Shenzhen [1] - Five companies from Wuhan, including He Yuan Bio, Aibotai, and Youzhiyou, were ranked among the top 20 most innovative enterprises from hundreds of projects across 23 national bio-industry bases [1] Group 2: Achievements in Bio-Medicine - In the first half of the year, Optics Valley Bio-City approved 14 new class I innovative drugs for clinical trials, the highest number in three years, and 28 class III medical devices, matching last year's total [4] - The city is currently developing over 400 class I new drugs, accounting for 90% of the province's total, and has certified over 307 class III medical devices, representing 70% of the province's total [4] Group 3: Notable Exhibits - Major companies from Optics Valley Bio-City showcased groundbreaking products at the conference, including the world's first 5.0T whole-body MRI system and a novel "rice-derived" recombinant human albumin injection [4] - Binhui Bio's OH2 injection, the first oncolytic virus drug using type II herpes simplex virus as a carrier, is undergoing critical clinical research and has received national support for major new drug development [4]

Investment Rating - The report does not explicitly state an investment rating for the synthetic biology industry Core Insights - The synthetic biology sector is experiencing a global biotechnology revolution, providing innovative solutions to major challenges such as health, climate change, resource security, and food security. The National Development and Reform Commission has issued the "14th Five-Year Plan for the Development of the Bioeconomy," indicating a trillion-yuan market potential in the bioeconomy [4][5] Market Performance - The Huazhong Synthetic Biology Index rose by 14.49% to 1709.48 during the week of July 14-18, 2025, outperforming the Shanghai Composite Index by 13.8 percentage points and the ChiNext Index by 11.32 percentage points [5][18] - The overall performance of synthetic biology stocks was strong, with the top six performing companies being all from the pharmaceutical sector, including Kanghong Pharmaceutical (+22%) and Zhejiang Zhenyuan (+19%) [20][23] Company Developments - China National Pharmaceutical invested approximately 6.8 billion yuan to acquire 95.09% of Lixin Pharmaceutical, enhancing its R&D capabilities in oncology [26] - New Fengming invested 100 million yuan in Hefei Lifeng Biotechnology to promote the industrialization of bio-based polyester PEF [26] - Sichuan Huanlong Ecological Technology received approval for a 1.5 billion yuan bamboo fiber project, expected to produce 250,000 tons of bleached bamboo pulp annually [27] - Cargill and HELM AG launched the world's largest bio-based BDO project in Iowa, with an investment of 300 million USD, showcasing the potential of bio-based materials in the chemical industry [29] Industry Financing - The synthetic biology sector has seen accelerated financing, with nearly 100 companies completing new funding rounds in 2025. Notable examples include Tuoxin Tiancheng, which raised nearly 40 million USD for T-cell immunotherapy product development [35] - Illimis Therapeutics completed a 58 billion KRW (approximately 42 million USD) B round financing to advance its Alzheimer's disease candidate [35] Research and Development - Fuhong Hanlin announced the completion of the first patient dosing of its innovative HER2 antibody HLX22 in the US, marking a significant milestone in cancer treatment [39] - He Yuan Biotechnology's plant-derived recombinant human serum albumin received approval, representing a breakthrough in the field of plant-based recombinant protein drugs [39]