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“封闭的水”能促进分子间“联姻”
Ke Ji Ri Bao· 2025-11-12 00:22
Core Insights - The research conducted by German scientists reveals that "trapped water" in specific structures can influence the surrounding environment and facilitate molecular interactions, potentially paving the way for new drug and material development [1][2]. Group 1: Research Findings - The study identifies the phenomenon of "high-energy water," which exists in confined spaces and exhibits energy states higher than ordinary water, impacting molecular binding processes [1][2]. - The research utilized cucurbituril as a "host" molecule, demonstrating that high-energy water molecules are crucial driving forces in molecular binding, with higher energy levels favoring the binding of guest molecules [2]. Group 2: Implications for Medicine and Materials Science - In drug design, recognizing high-energy water in target proteins can aid in the systematic design of active molecules that can replace this water, enhancing drug efficacy by anchoring more firmly to proteins [2]. - In materials science, designing cavities that can expel or replace high-energy water may improve the sensing and storage capabilities of materials [2].
瑞普生物:公司坚持创新驱动高质量发展,积极加快第三代疫苗与新型药物开发
Core Viewpoint - The company emphasizes innovation-driven high-quality development in response to profound changes in the animal health industry [1] Group 1: Strategic Initiatives - The company is accelerating the development of third-generation vaccines and new drugs [1] - There is a continuous deepening of strategic cooperation with breeding groups [1] Group 2: Long-term Strategies - The company is advancing internationalization, pet economy, and synthetic biology as part of its medium to long-term strategies [1] - These initiatives are aimed at laying a solid foundation for high-quality development and creating long-term investment value for shareholders [1]