Core Insights - The article emphasizes the significant potential of food biosynthesis technology in addressing global food supply issues, meeting health and nutrition demands, and tackling environmental challenges [1][3]. Group 1: Opportunities in Food Biosynthesis - Food biosynthesis, based on synthetic biology and precision fermentation, can alleviate food supply pressures and provide a solid foundation for green and sustainable food production, driving deep transformation in the food industry [1]. - Countries worldwide are prioritizing the development of food biosynthesis, with Japan and the U.S. implementing strategic plans to promote food innovation, and China highlighting biomanufacturing in its national development strategies [3]. Group 2: Typical Applications of Food Biosynthesis - Key application areas include: 1. New protein sources 2. Oils 3. Starch 4. Food ingredients [4]. Group 3: Challenges in Food Biosynthesis - The design and efficient synthesis of new proteins are critical, requiring research in strain design, fermentation optimization, and food processing to create balanced and digestible alternative proteins [5]. - Establishing pathways for the biosynthesis of functional oils and developing efficient extraction and purification technologies are necessary for advancing new functional oil products [6]. - There is a need for innovative metabolic engineering or enzymatic synthesis pathways for new food functional ingredients to meet rising consumer demands for flavor and health attributes [7]. - Addressing the challenges in the biosynthesis of nutrients like vitamins and amino acids involves optimizing metabolic pathways and developing high-performance cell factories [8]. - Food biosynthesis also faces regulatory and safety challenges, necessitating the evolution of global regulatory frameworks to ensure safety while supporting industry growth [8]. Group 4: Summary and Outlook - The field of biomanufacturing, particularly through synthetic biology and precision fermentation, is entering a period of rapid development, providing essential technological support for addressing food manufacturing challenges [9]. - Significant progress has been made in the biosynthesis of new proteins, oils, starch, food ingredients, and nutrients, but challenges remain in various aspects of research and application [10]. - Future research directions include integrating AI with food biosynthesis technologies to create intelligent cell factories, expanding the range of synthetic products, and enhancing synthesis efficiency [10].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through synthetic biology initiatives [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing, along with four application areas: green chemicals and new materials, future food, future agriculture, and beauty raw materials [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, identify innovative technologies and products, and promote the transfer and commercialization of scientific achievements [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by various institutions, including the Chinese Society of Biotechnology and the Zhejiang Synthetic Biology Industry Technology Alliance [2]. Group 3: Conference Highlights - Key highlights include forums and closed-door activities to gain insights into the biomanufacturing development trends, sharing of innovative technologies, and over 100 financing project roadshows to discover new cooperation opportunities [2]. - The event will also feature a youth innovation technology forum to connect talents and share valuable insights [2]. Group 4: Conference Agenda - The first day will include a closed-door seminar focusing on the development trends and growth points of biomanufacturing, inviting 30 industry leaders and experts for in-depth discussions [7]. - The second and third days will feature a macro forum on the biomanufacturing industry, covering various specialized topics such as green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [10][12]. Group 5: Specialized Topics - Specialized forums will address topics like the development of bio-based chemicals, AI applications in enzyme discovery, and the biomanufacturing of high-value food ingredients [10][11]. - The conference will also showcase innovative projects and technologies in the field of synthetic biology and biomanufacturing, encouraging participation from research institutions and enterprises [12].

Core Viewpoint - The biomanufacturing industry is emerging as a new engine for economic growth, with a significant focus on the new protein sector as a key area for development [1][2]. Group 1: New Protein Manufacturing Center - The National Investment Group and Wuxi City have established the National Investment New Protein Biomanufacturing Innovation Center to address bottlenecks in new protein research and industrialization [2][4]. - The center aims to accelerate the development and cost optimization of various new protein products, covering fields such as food, nutrition, healthcare, and materials [2][4]. Group 2: Challenges and Opportunities - New protein is defined as edible protein not reliant on traditional livestock or fishery methods, utilizing innovative technologies like microbial fermentation and synthetic biology [4]. - China faces a significant protein gap, with 2024 grain imports projected to exceed 158 million tons, including 105 million tons of soybeans, which are primarily used for animal feed [5]. - The shortage of edible protein has become a safety issue, prompting the government to promote comprehensive food resource development [5]. Group 3: Investment and Development Strategy - Since 2020, the new protein industry in China has shown strong growth, although the capital market's downturn in 2023 has posed challenges [5][6]. - The National Investment Group has established the National Investment Biomanufacturing Innovation Research Institute with a registered capital of 6 billion yuan, marking a significant step in supporting the biomanufacturing industry [5][6]. - The group aims to achieve a total output value of 60 billion yuan in the biomanufacturing sector by the end of the 14th Five-Year Plan [6]. Group 4: Financial Support and Collaboration - The National Investment Group manages funds exceeding 270 billion yuan, having invested over 4 billion yuan in 25 biomanufacturing companies [6][7]. - The group has partnered with various local governments to establish industry guidance funds, including a 2 billion yuan biomanufacturing venture capital fund in Tianjin [6][7]. - Future plans include collaborating with private capital to explore differentiated management of mixed-ownership enterprises, enhancing the vitality and competitiveness of the industry [7].

Core Insights - The National Investment Group (国投) is establishing a dedicated CVC fund for the biomanufacturing industry, focusing on early-stage, small investments in hard technology to support strategic emerging industries and core technology breakthroughs [1][3] - The biomanufacturing industry is recognized as a new engine for economic growth, with the establishment of the National Investment Group's new protein biomanufacturing innovation center aimed at addressing bottlenecks in new protein research and industrialization [1][2] Group 1: Industry Development - The new protein, which does not rely on traditional livestock or fishery methods, is synthesized using innovative technologies like microbial fermentation, addressing the significant protein gap in China, where over 66% of grain imports are soybeans [2] - The shortage of edible protein has become a safety issue, prompting the government to promote a comprehensive approach to food resource development [2] Group 2: Investment and Funding - The National Investment Group has invested in 25 biomanufacturing companies, totaling over 4 billion yuan, and has established various government-guided funds to support the industry [4] - The National Investment Group's funds exceed 270 billion yuan, with investments in 424 specialized enterprises, supporting 120 companies to go public, which constitutes 10% of the total on the Science and Technology Innovation Board [3][4] Group 3: Strategic Initiatives - The establishment of the National Investment Group's Biomanufacturing Innovation Research Institute, with a registered capital of 6 billion yuan, marks a strategic initiative to cultivate the biomanufacturing industry [3] - The National Investment Group aims to achieve a total output value of 60 billion yuan in the biomanufacturing sector by the end of the 14th Five-Year Plan, focusing on various sub-sectors such as industrial strains and food additives [3]