注射用重组人促甲状腺激素(rhTSH)

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泽璟制药(688266):吉卡昔替尼将参与医保谈判,多抗组合覆盖优势领域
Huaan Securities· 2025-08-28 02:32
Investment Rating - The report maintains a "Buy" rating for the company, indicating a positive outlook for future investment returns [10]. Core Insights - The company reported a revenue of 376 million yuan for the first half of 2025, representing a year-on-year increase of 56.07%. However, the net profit attributable to the parent company was a loss of 73 million yuan, a decrease of 9.42% year-on-year [5]. - The company is advancing its commercialization process, with the drug Jika Xiqi (盐酸吉卡昔替尼) preparing for negotiations to be included in the national medical insurance directory [7]. - The company has made significant progress in its innovative pipeline, with multiple bispecific antibodies entering clinical trials and showing promising results [8]. Financial Performance - The overall gross margin for the first half of the year was 89.67%, a decrease of 3.07 percentage points year-on-year. The operating cash flow was negative 17 million yuan, a decline of 115.12% year-on-year [6]. - The company expects revenues of 900 million yuan, 1.65 billion yuan, and 2.41 billion yuan for 2025, 2026, and 2027, respectively, with corresponding year-on-year growth rates of 68.7%, 83.2%, and 46.2% [10]. - The projected net profit attributable to the parent company for the same years is 73 million yuan, 530 million yuan, and 1.02 billion yuan, with year-on-year growth rates of 152.7%, 628.6%, and 93.1% [10]. Product Development - The company’s drug ZGGS15 (LAG3/TIGIT) has received IND approval in both China and the US, marking it as the first of its kind to enter clinical research [8]. - The drug Zepu Ping (盐酸吉卡昔替尼片) was approved for market entry in May 2025 and is set to participate in the national medical insurance negotiations [9]. - The company has established a commercial presence in over 1,200 hospitals and 2,200 pharmacies for its product Zepu Sheng (甲磺酸多纳非尼片) [9].
泽璟制药(688266):2025年半年报点评:商业化品种持续放量,在研管线进展顺利
Western Securities· 2025-08-26 11:31
Investment Rating - The investment rating for the company is "Buy" [6] Core Views - The company reported a revenue of 376 million yuan in the first half of 2025, representing a year-on-year increase of 56.07%. However, it recorded a net loss attributable to shareholders of 72.8 million yuan, with a slight increase in losses compared to the previous year [1][6] - The commercialized products, including Donafenib and recombinant human thrombin, are showing steady growth. Donafenib has been introduced in over 1,200 hospitals, while recombinant human thrombin has been included in the national medical insurance directory for 2024, with significant sales growth [1][2] - The company has multiple promising pipelines, including ZG006 and ZG005, which are showing good efficacy and safety in clinical trials for various cancers [2] Summary by Sections Financial Performance - In the first half of 2025, the company achieved a revenue of 376 million yuan, with a year-on-year growth of 56.07%. The net profit attributable to shareholders was -72.8 million yuan, and the net profit after deducting non-recurring items was -103 million yuan, indicating a slight increase in losses compared to the previous year [1][6] - Revenue projections for 2025 to 2027 are estimated at 825 million yuan, 1.36 billion yuan, and 1.94 billion yuan, respectively, with growth rates of 54.8%, 65.2%, and 42.6% [2][4] Product Pipeline - The company is actively promoting its products, with Donafenib and recombinant human thrombin showing robust market penetration. Donafenib has been introduced in over 1,200 hospitals, while recombinant human thrombin has been adopted by over 590 hospitals [1][2] - The company has received approval for the marketing of Jikaxitinib for bone marrow fibrosis and is progressing with its NDA application for severe alopecia areata [1] - ZG006 has shown significant anti-tumor activity in clinical trials for small cell lung cancer, and ZG005 is being developed for multiple solid tumors [2]