地缘风险催化下，生命科学上游(细胞培养基、生物试剂、层析介质等)国产替代需求迫切，目前细分领 域国内市占率低，各企业有望凭借新分子品类或高性价比产品抢占市占率。叠加国内与海外新靶点新机 理研发需求提升，带动细分赛道(如药效、抗体、蛋白质等)需求增长，行业长期成长逻辑清晰，短期业 绩边际改善显著。 广发证券主要观点如下： 国内投融资研发需求修复，叠加行业订单价格企稳CRO企业底部向上趋势明确 国内研发需求端边际改善，创新药出海BD带动研发积极性回升，国内研发订单需求增长，行业价格自 2023年降价后已见底企稳，部分领域略有回升。临床CRO(泰格医药（300347）、诺思格（301333）、 普蕊斯（301257）)2025年营收增速已逐步转正，临床前CRO业绩亦持续改善;扣非归母净利润环比修复 显著;国内CRO临床数据认可度提升，泰格医药海外业务贡献总量显著。预计2026年整个板块将迎来更 好的业绩增长。 CDMO新签订单延续季度改善趋势，行业新分子为行业发展带来新增量 2025年CDMO业绩已触底回升，全球创新药研发需求复苏带动行业新签订单与在手订单整体保持增长， 新分子赛道需求打开增量空间;同时，前期产能建 ...

Core Viewpoint - The domestic R&D demand is showing marginal improvement, driven by the overseas expansion of innovative drugs, leading to a recovery in R&D orders and stabilization of industry prices after a decline in 2023. The CRO sector is expected to see better performance growth by 2026, while the CDMO industry has also reached a bottom and is poised for continued strong growth due to robust demand for new molecules and new orders [1][2][3]. CRO Sector - The domestic R&D demand is recovering, with an increase in orders and stabilization of prices, indicating a clear upward trend for CRO companies. Clinical CROs like Tigermed, Nossan, and Prasis are expected to see revenue growth turning positive by 2025, with significant contributions from overseas business [2][3]. - The recognition of domestic CRO clinical data is improving, which is beneficial for companies like Tigermed [2]. CDMO Sector - The CDMO sector has seen a recovery in performance, with new orders continuing to improve quarterly. The global demand for innovative drug R&D is driving growth in new orders and backlog [3]. - The industry is benefiting from increased capacity utilization and profitability, with a strong certainty of performance and profit growth expected to continue into 2026 [3]. Life Sciences Sector - The life sciences upstream sector is experiencing a dual drive from domestic substitution and overseas expansion, with urgent demand for domestic alternatives in areas like cell culture media and biological reagents. Companies are expected to capture market share through new product categories and cost-effective offerings [4]. - The demand for specific segments such as drug efficacy, antibodies, and proteins is increasing, indicating a clear long-term growth logic for the industry [4]. API Sector - The raw material pharmaceutical industry is currently in a phase of price bottoming and supply surplus, with traditional product performance under pressure. However, companies are extending their business into generics, innovative drugs, and specialty APIs, which may lead to value reconstruction through business structure optimization [5]. - The valuation of raw material pharmaceutical companies is at a low point, presenting opportunities based on changes in new business layouts [5]. Investment Recommendations - For clinical and preclinical CROs, companies like Tigermed, Nossan, and Yinos are recommended due to the gradual recovery of the industry and expected improvement in order structure [6]. - In the CDMO sector, companies such as WuXi AppTec, WuXi Biologics, and others with strong fundamentals and capacity advantages are highlighted for their potential benefits from industry recovery and high demand for new molecules [6]. - In the life sciences upstream sector, companies like Baitai Biotechnology and others are recommended due to accelerated domestic substitution and strong overseas growth [6]. - Companies like Pro Pharma and Huahai Pharmaceutical are noted for their new business layouts that are expected to contribute significant value increments [6].

分红方面，诺唯赞A股上市后累计派现7.31亿元。近三年，累计派现6.11亿元。 责任编辑：小浪快报 资料显示，南京诺唯赞生物科技股份有限公司位于江苏省南京经济技术开发区科创路红枫科技园D2 栋，成立日期2012年3月16日，上市日期2021年11月15日，公司主营业务涉及围绕酶、抗原、抗体等功 能性蛋白及高分子有机材料进行技术研发和产品开发的生物科技企业,依托于自主建立的关键共性技术 平台,先后进入了生物试剂、体外诊断业务领域,并正在进行抗体药物的研发。主营业务收入构成为：生 物试剂81.86%，诊断试剂9.99%，耗材等材料3.15%，仪器设备2.96%，技术服务1.85%，其他0.18%。 截至9月30日，诺唯赞股东户数9447.00，较上期增加9.90%；人均流通股42101股，较上期减少9.01%。 2025年1月-9月，诺唯赞实现营业收入9.52亿元，同比减少3.40%；归母净利润661.52万元，同比减少 63.57%。 11月12日，诺唯赞涨1.01%，成交额6078.49万元。两融数据显示，当日诺唯赞获融资买入额325.00万 元，融资偿还491.88万元，融资净买入-166.88万元。截至1 ...

Summary of Key Points Core Viewpoint - NuoVaxan's stock performance and financing activities indicate a mixed sentiment among investors, with a notable decrease in revenue and net profit year-on-year, suggesting potential challenges ahead for the company [1][2]. Group 1: Stock Performance and Financing - On November 11, NuoVaxan's stock rose by 0.17% with a trading volume of 36.08 million yuan [1]. - The financing buy-in amount for NuoVaxan on the same day was 3.48 million yuan, while the financing repayment was 4.09 million yuan, resulting in a net financing outflow of 610,400 yuan [1]. - As of November 11, the total financing and securities lending balance for NuoVaxan was 94.44 million yuan, with the financing balance at 93.64 million yuan, accounting for 0.99% of the circulating market value, indicating a high level compared to the past year [1]. Group 2: Company Overview and Financial Performance - NuoVaxan, established on March 16, 2012, and listed on November 15, 2021, specializes in the research and development of functional proteins and high molecular organic materials, with a focus on biological reagents and in vitro diagnostics [2]. - The company's revenue composition includes 81.86% from biological reagents, 9.99% from diagnostic reagents, 3.15% from consumables, 2.96% from equipment, 1.85% from technical services, and 0.18% from other sources [2]. - For the period from January to September 2025, NuoVaxan reported a revenue of 952 million yuan, a year-on-year decrease of 3.40%, and a net profit attributable to shareholders of 6.62 million yuan, down 63.57% year-on-year [2]. Group 3: Dividend Information - Since its A-share listing, NuoVaxan has distributed a total of 731 million yuan in dividends, with 611 million yuan distributed over the past three years [3].

Group 1 - The core viewpoint of the news is that NuoVas has experienced fluctuations in its stock performance and financing activities, indicating a high level of trading activity and potential investor interest [1][2]. - On November 6, NuoVas' stock price decreased by 0.61%, with a trading volume of 32.48 million yuan. The financing buy-in amount was 2.79 million yuan, while the financing repayment was 2.27 million yuan, resulting in a net financing buy-in of 0.52 million yuan [1]. - As of November 6, the total balance of margin trading for NuoVas was 99.09 million yuan, with the financing balance accounting for 1.08% of the circulating market value, indicating a high level compared to the past year [1]. Group 2 - NuoVas, established on March 16, 2012, and listed on November 15, 2021, focuses on the research and development of functional proteins and high molecular organic materials, with a revenue composition of 81.86% from biological reagents, 9.99% from diagnostic reagents, and 3.15% from consumables [2]. - For the period from January to September 2025, NuoVas reported a revenue of 0.952 billion yuan, a year-on-year decrease of 3.40%, and a net profit attributable to shareholders of 6.62 million yuan, down 63.57% year-on-year [2]. - NuoVas has distributed a total of 0.731 billion yuan in dividends since its A-share listing, with 0.611 billion yuan distributed over the past three years [3].

Core Viewpoint - The company reported Q3 2025 revenue of 226 million yuan (+37.5% YoY) and a net profit attributable to shareholders of 48.62 million yuan (+81.5% YoY), continuing a high growth trend in performance [1] - The gross margin for Q3 2025 increased to 93.1%, with stable expense growth, indicating significant profit elasticity due to revenue realization [1] - The company plans to list in Hong Kong, which is expected to enhance its international strategy, expand overseas business, and improve overall competitiveness [1] Financial Performance - For the first three quarters of 2025, the company achieved revenue of 613 million yuan (+32.3% YoY) and a net profit attributable to shareholders of 132 million yuan (+58.6% YoY) [1] - The adjusted net profit for the same period was 133 million yuan (+58.8% YoY) [1] Profit Forecast and Investment Recommendation - Based on the Q3 report, the profit forecasts for 2025-2027 have been revised upwards, with expected net profits of 191 million yuan, 271 million yuan, and 357 million yuan respectively [2] - The target price is set at 86.94 yuan, based on a 54x PE valuation for 2026, maintaining a "buy" rating [2]

Group 1: Industry Overview - The pharmaceutical and biotechnology industry is entering a new upward cycle, with accelerated overseas orders and strong upward momentum, particularly for companies with strong overseas capabilities in the upstream biological sector [1] - The early-stage CRO (Contract Research Organization) industry is experiencing a significant development opportunity, driven by the historical chance for innovative drugs to expand internationally [1] Group 2: Early-stage CRO - The early-stage CRO industry is seeing a shift towards domestic advantages in quality, efficiency, and cost, as overseas demand for early-stage research increases [1] - The demand for preclinical and safety evaluation orders is gradually recovering, with a recommendation to focus on leading companies such as Yino Science and Zhaoyan New Drug [1] - The supply-demand mismatch for experimental monkeys is expected to persist, leading to stable prices in the short term [1] Group 3: Upstream Biological Products - The domestic biological sector is recovering quickly, with significant growth expected in biological reagents, including culture media and recombinant proteins, driven by the structural recovery from domestic innovative drug exports [2] - The overseas market presents vast opportunities, and domestic brands are favored for their cost-effectiveness, suggesting a focus on companies with overseas capabilities such as Baipusais and Haoyuan Pharmaceutical [2] Group 4: Clinical CRO - The clinical CRO sector is approaching a turning point, with SMO (Site Management Organization) orders showing early signs of recovery [3] - As innovative drug financing improves, the number of clinical projects is expected to increase, leading to a recovery in overall orders [3] - Leading clinical CRO companies such as Tigermed and Nossger are recommended for investment [3] Group 5: CDMO - The CDMO (Contract Development and Manufacturing Organization) sector is showing strong performance, particularly in the peptide and ADC (Antibody-Drug Conjugate) segments, which are expected to maintain high growth rates [4] - New molecular tracks, including small nucleic acids, also present significant long-term development potential [4] - Recommended CDMO leaders include Kelaiying and WuXi AppTec, which are expected to show performance elasticity due to stable small molecule business and rapid growth in new molecular business [4]

Core Points - The stock price of NuoVasive increased by 2.05% on October 27, reaching 22.92 CNY per share, with a total market capitalization of 9.116 billion CNY [1] - The company has seen a year-to-date stock price increase of 4.09%, with a 4.37% rise over the last five trading days [1] Company Overview - NuoVasive, established on March 16, 2012, and listed on November 15, 2021, is a biotechnology company based in Nanjing, Jiangsu Province, focusing on the research and development of functional proteins and high molecular organic materials [1] - The company's main business revenue composition includes: 81.86% from biological reagents, 9.99% from diagnostic reagents, 3.15% from consumables, 2.96% from equipment, 1.85% from technical services, and 0.18% from other sources [1] Financial Performance - For the first half of 2025, NuoVasive reported a revenue of 606 million CNY, a year-on-year decrease of 6.63%, and a net profit attributable to shareholders of 3.1294 million CNY, down 80.63% year-on-year [2] - The company has distributed a total of 731 million CNY in dividends since its A-share listing, with 611 million CNY distributed over the past three years [3] Shareholder Information - As of June 30, the number of shareholders for NuoVasive was 8,596, an increase of 2.37% from the previous period, with an average of 46,269 circulating shares per shareholder, a decrease of 2.31% [2]

Core Points - The stock price of NuoVivian increased by 2.10% on October 15, reaching 22.82 CNY per share, with a total market capitalization of 9.076 billion CNY [1] - The company has seen a year-to-date stock price increase of 3.63%, but has experienced a decline of 1.68% over the last five trading days [1] - NuoVivian's main business involves the research and development of functional proteins and high molecular organic materials, with a revenue composition of 81.86% from biological reagents and 9.99% from diagnostic reagents [1] Financial Performance - As of June 30, NuoVivian had 8,596 shareholders, an increase of 2.37% from the previous period, while the average circulating shares per person decreased by 2.31% to 46,269 shares [2] - For the first half of 2025, NuoVivian reported a revenue of 606 million CNY, a year-on-year decrease of 6.63%, and a net profit attributable to shareholders of 3.1294 million CNY, down 80.63% year-on-year [2] Dividend Information - Since its A-share listing, NuoVivian has distributed a total of 731 million CNY in dividends, with 611 million CNY distributed over the past three years [3]

Company Overview - NuoVance Biotechnology Co., Ltd. is located in Nanjing Economic and Technological Development Zone, Jiangsu Province, and was established on March 16, 2012. The company went public on November 15, 2021. Its main business involves the research and development of functional proteins and high molecular organic materials, focusing on enzymes, antigens, and antibodies [1][2]. Financial Performance - For the first half of 2025, NuoVance reported operating revenue of 606 million yuan, a year-on-year decrease of 6.63%. The net profit attributable to shareholders was 3.1294 million yuan, down 80.63% year-on-year [2]. - Since its A-share listing, NuoVance has distributed a total of 731 million yuan in dividends, with 611 million yuan distributed over the past three years [3]. Stock Performance - As of October 14, NuoVance's stock price increased by 2.00% to 22.92 yuan per share, with a trading volume of 21.1964 million yuan and a turnover rate of 0.24%. The total market capitalization is 9.116 billion yuan [1]. - Year-to-date, the stock price has risen by 4.09%, but it has seen declines of 0.52% over the last five trading days, 2.76% over the last 20 days, and 1.55% over the last 60 days [1]. Shareholder Information - As of June 30, NuoVance had 8,596 shareholders, an increase of 2.37% from the previous period. The average number of tradable shares per shareholder was 46,269, a decrease of 2.31% [2]. Business Segments - The company's main revenue sources are as follows: biological reagents (81.86%), diagnostic reagents (9.99%), consumables and materials (3.15%), instruments and equipment (2.96%), technical services (1.85%), and others (0.18%) [1].