Investment Rating - The investment rating for the company is "Accumulate" (maintained) [3] Core Views - The company reported a revenue of 925 million yuan for 2024, representing a year-on-year growth of 9.1%, and a net profit attributable to shareholders of 317.8 million yuan, up 2.5% year-on-year [5] - The company is expected to achieve revenue of 1,033 million yuan in 2025, with a growth rate of 11.6%, and a net profit of 351.9 million yuan, reflecting a growth of 10.7% [5] - The company maintains a strong market position with over 80% market share in the domestic allergy treatment sector, and its product pipeline continues to expand [5] Financial Performance Summary - For 2024, the company achieved a gross margin of 95.16% and a stable expense ratio, with sales expense ratio at 39.06% [5] - The company’s R&D expenses for 2024 were 120 million yuan, accounting for 12.95% of revenue [5] - The earnings per share (EPS) for 2024 is projected to be 0.61 yuan, with a P/E ratio of 34.5 [3][5] Revenue and Profit Forecast - The forecasted revenues for 2025-2027 are 1,033 million yuan, 1,171 million yuan, and 1,354 million yuan, respectively, with corresponding year-on-year growth rates of 11.6%, 13.3%, and 15.7% [5] - The net profit forecast for the same period is 351.9 million yuan, 394.0 million yuan, and 450.2 million yuan, with growth rates of 10.7%, 12.0%, and 14.3% [5] Product Pipeline and Market Expansion - The company has successfully expanded its product matrix, with new products such as "Skin Prick Test Solutions" receiving approval for market entry [5] - The company is actively promoting its products in northern markets, leading to significant sales increases, particularly for the Dust Mite Drops and Artemisia Pollen Drops [5]

Core Viewpoint - The company reported steady revenue growth and a continuous expansion of its core product matrix, with a positive outlook for future performance driven by increased market penetration and new product launches [1][2][4]. Financial Performance - In 2024, the company achieved operating revenue of 925 million yuan, a year-on-year increase of 9.10%, and a net profit attributable to shareholders of 318 million yuan, up 2.46% [1]. - For Q1 2025, the company reported operating revenue of 228 million yuan, a year-on-year increase of 5.65%, but a net profit decrease of 3.71% to 74 million yuan [1][2]. Product Performance - The company’s core products, particularly the dust mite drops, showed strong sales, generating 886 million yuan in 2024, a growth of 7.86% [2]. - The yellow flower pollen drops saw significant growth, with revenue reaching 27.01 million yuan in 2024, a year-on-year increase of 76.43%, driven by enhanced marketing efforts in northern markets [2]. - The skin prick solution also performed well, with revenue of 7.30 million yuan, reflecting a growth of 103.08% [2]. R&D and Product Pipeline - The company has expanded its product pipeline, with eight skin prick products approved for market launch and ongoing clinical trials for new drugs [2]. - The "house dust mite membrane agent" is entering Phase I clinical trials, while a new chemical drug is in Phase II [2]. Profitability and Cost Management - The overall gross margin remained stable at 95.16% in 2024 and 94.76% in Q1 2025 [3]. - The sales expense ratio increased to 39.06% in 2024 and 40.37% in Q1 2025, attributed to increased promotional activities [3]. - R&D expenses were 120 million yuan in 2024, reflecting a 6.85% increase, with a R&D expense ratio of 12.95% [3]. Future Outlook - Revenue projections for 2025-2027 are set at 1.033 billion, 1.171 billion, and 1.354 billion yuan, with expected growth rates of 11.6%, 13.3%, and 15.7% respectively [4]. - Net profit forecasts for the same period are 352 million, 394 million, and 450 million yuan, with growth rates of 10.7%, 12.0%, and 14.3% [4]. - The company maintains a leading market share of over 80% in the domestic allergy treatment market, with a strong outlook for continued growth [4].

Core Insights - Zhejiang Iwu Biological Technology Co., Ltd. has made significant progress in the field of allergic disease diagnostics with the approval of its "Dermatitis Diagnostic Patch 02" for clinical trials by the National Medical Products Administration [1][5] Group 1: Product Development - The "Dermatitis Diagnostic Patch 02" focuses on diagnosing three common allergens: Kathon, p-phenylenediamine, and formaldehyde, which are frequently encountered in daily life and are known to cause allergic contact dermatitis [4][6] - The clinical trial process will follow a rigorous drug development protocol, including Phase I, II, and III trials to assess safety, efficacy, and dosage [5][6] Group 2: Market Position and Impact - Iwu Biological is a leading domestic pharmaceutical company specializing in the research and innovation of allergic disease diagnostics and treatments, with a strong R&D team and a history of successful product launches [6][7] - The approval of the "Dermatitis Diagnostic Patch 02" is expected to enhance the company's competitiveness in the diagnostic market and contribute to the development of the allergic disease diagnostics sector in China [6][7]

本文来自微信公众号：新周刊 （ID：new-weekly），作者：赵皖西，编辑：詹腾宇，校对：遇见，题图来自：AI生成 《过敏星人生存宝典》 作者：孙宝清团队 出版社：中信出版社 广州的棉絮已经偃旗息鼓，武汉的樱花渐渐凋零，北京的玉兰也相继落下——随着五一假期结束，春天正以极快的速度向北撤退。 当通勤路上漫天飞舞的杨絮、柳絮消失不见，"过敏星人"正准备放下心理防备时，"过敏刺客"却以尘螨、霉菌、紫外线等形式继续侵扰我们的生活。 免疫系统的叛逆期，比我们想象中的漫长很多。 普通人的四季是春天赏花，夏天旅游，秋天爬山，冬天赏雪，但"过敏星人"的四季是春天遭受花粉、柳絮过敏，夏天被紫外线、蚊虫侵扰，秋天换季时候 皮肤过敏，冬天受到冷空气刺激。他们不是在过敏，就是在抗过敏和抵抗过敏焦虑的路上。 过敏，一场全民参与的"免疫抵抗" 如今，过敏已经成为全球第六大慢性病，影响了约三分之一的人群。 早在2011年，WAO（世界变态反应组织）就指出，全世界有30%~40%的人正在被过敏疾病影响，这相当于，每10个人中，就有3个人是过敏体质。 由广州医科大学附属第一医院孙宝清教授及其团队撰写的《过敏星人生存宝典》指出，全球有2.4 ...

Investment Rating - The report maintains a "Buy" rating for the company [3][11]. Core Views - The company's core product, Dust Mite Drops, is steadily growing, while the new product, Artemisia Annua Drops, is rapidly gaining market traction. The company is also expanding its product line with various prick test solutions and making continuous progress in R&D [3][11]. - The revenue for 2024 is projected to be 925 million yuan, reflecting a growth of 9.1%, with a net profit of 318 million yuan, an increase of 2.5% [11]. - The company is focusing on enhancing its market presence, particularly in northern regions, and has initiated patient assistance programs to improve product coverage [11]. Financial Summary - **Revenue and Profit Forecasts**: - 2023A: Revenue 848 million yuan, Net Profit 310 million yuan - 2024A: Revenue 925 million yuan (+9.1%), Net Profit 318 million yuan (+2.5%) - 2025E: Revenue 1,061 million yuan (+14.6%), Net Profit 353 million yuan (+11.0%) [5][12]. - **Earnings Per Share (EPS)**: - 2024A: 0.61 yuan - 2025E: 0.67 yuan - 2026E: 0.79 yuan - 2027E: 0.92 yuan [11][12]. - **Valuation Metrics**: - The report assigns a PE ratio of 35X for 2025, with a target price of 23.58 yuan [11][12]. Product Performance - **Dust Mite Drops**: Revenue reached 886 million yuan in 2024, growing by 7.86% [11]. - **Artemisia Annua Drops**: Revenue of 27.01 million yuan, a significant increase of 76.43% [11]. - **Prick Test Solutions**: Revenue of 7.30 million yuan, with a growth of 103.08% due to new product approvals [11]. R&D Progress - The company has multiple projects in the pipeline, including new prick test solutions and clinical trials for various products, indicating a robust R&D strategy [11].

Core Viewpoint - Iwubio has demonstrated steady growth in its financial performance, with a focus on innovation in the desensitization treatment sector, positioning itself as a leader in a competitive market [1] Group 1: Financial Performance - For the year 2024, Iwubio reported a revenue of 925 million yuan, representing a year-on-year growth of 9.10% [1] - The net profit attributable to shareholders was 318 million yuan, an increase of 2.46% year-on-year [1] - In Q1 2025, the company achieved a revenue of 228 million yuan, up 5.7% year-on-year, with a net profit of 74 million yuan, reflecting a growth of 1.5% [1] - Operating cash flow for Q1 2025 reached 85.88 million yuan, marking a significant increase of 96.2% [1] - Cumulatively, the company has distributed over 850 million yuan in cash dividends since its listing, which is approximately four times the amount raised during its IPO [1] Group 2: Competitive Advantages - Iwubio has established three competitive barriers: technological innovation, product scarcity, and industry leadership [2][3][4] - The company invested 125 million yuan in R&D in 2024, accounting for 13.48% of its revenue, which is above the industry average [2] - Iwubio's product "Dust Mite Drops" is the only sublingual desensitization treatment available in China, providing a significant advantage in terms of safety and convenience compared to subcutaneous alternatives [3] - The market share of Iwubio's "Dust Mite Drops" has consistently remained above 81.72%, confirming its leading position in the domestic desensitization treatment market [4] Group 3: Growth Potential - The allergy treatment market is expected to grow due to the increasing prevalence of allergic diseases, with reports indicating that around 40% of the Chinese population suffers from such conditions [5] - Iwubio's "Dust Mite Drops" and "Artemisia Pollen Sublingual Drops" have shown significant growth, with the latter achieving a 76.43% increase in 2024 [5] - The company is expanding its product offerings in the allergy testing market, with new products like "Pollen Skin Prick Test Solutions" receiving market approval [5] - Iwubio is also venturing into stem cell therapies and natural medicines, aiming to create a second growth curve [6] - The company has identified a drug molecule for antibiotic-resistant tuberculosis and is advancing its clinical research [6] Group 4: Strategic Outlook - Iwubio's strategic positioning in the allergy treatment sector, combined with its innovative approaches in stem cell and natural medicine, suggests a robust growth trajectory [7] - The company is well-positioned to navigate the evolving pharmaceutical landscape, focusing on both maintaining its core allergy treatment business and exploring new therapeutic areas [7]

Group 1: Market Competition and Product Strategy - The domestic allergy treatment market growth has slowed to 8%, with competitors like Novartis and ALK accelerating sublingual desensitization therapy [1] - The company has three dust mite desensitization drugs approved for nationwide sale, including its own "Dust Mite Drops" [1] - The company is not concerned about competition, believing that more participants can help expand the market [1] Group 2: Cost Structure and Financial Management - The company's main product costs remained stable in 2024, with a high gross margin [2] - Future cost optimization will focus on external procurement and production planning, although the potential for significant cost reduction is limited due to high margins [2] - The company has entrusted financial management with an amount of 206.5 million yuan, with an unexpired balance of 194.838 million yuan [2] Group 3: Research and Development Focus - The company is developing new major medical products, including stem cell therapies and natural drugs (anti-drug-resistant antibiotics) [2][4] - Current R&D investments are primarily focused on allergen products, with plans to enter new medical fields [4] - New drug development cycles are long and risky, making it difficult to predict product launch timelines [4] Group 4: Industry Standards and Regulatory Compliance - The company has established its own drug registration standards, which have been approved by the National Medical Products Administration [4] - Participation in industry standard formulation enhances the company's influence and competitiveness in the allergy treatment sector [4]