财务报表中对有大幅变动的财务项目的原因说明如下：经营活动产生的现金流量净额变动幅度为 96.08%,原因:销售商品收到的现金增加。投资活动产生的现金流量净额变动幅度为41.17%,原因:支付的 工程项目施工及投标保证金减少。筹资活动产生的现金流量净额变动幅度为-569.46%,原因:分配股利支 付的现金增加。现金及现金等价物净增加额变动幅度为102.17%,原因:经营活动产生的现金流量净额增 加、投资活动产生的现金流量净额增加以及筹资活动产生的现金流量净额减少共同影响。 据证券之星公开数据整理，近期我武生物(300357)发布2025年中报。截至本报告期末，公司营业总收入 4.84亿元，同比上升12.81%，归母净利润1.77亿元，同比上升18.61%。按单季度数据看，第二季度营业 总收入2.56亿元，同比上升20.07%，第二季度归母净利润1.03亿元，同比上升42.55%。本报告期我武生 物盈利能力上升，毛利率同比增幅0.16%，净利率同比增幅5.93%。 证券之星价投圈财报分析工具显示：业务评价：公司去年的ROIC为11.28%，资本回报率一般。然而去 年的净利率为32.89%，算上全部成本后，公司产品 ...

证券代码：300357 证券简称：我武生物 浙江我武生物科技股份有限公司投资者关系活动记录表 编号：2025-004 3 | 投资者关系活 | □特定对象调研 | □分析师会议 □媒体采访 | | --- | --- | --- | | 动类别 | □业绩说明会 | □新闻发布会 □路演活动 | | | □现场参观 | ■其他（分析师电话会议） | | 参与单位名称 及人员姓名 | 共 47 家机构共计 58 | 名人员参加，详见附件。 | | 时间 | 年 月 日 2025 8 22 | 9:00-9:45 | | 地点 | 电话会议 | | | 上市公司接待 | | 董事长：胡赓熙；总经理：何建明；副总经理/董事会秘书：管祯 | | 人员姓名 | 玮。 一、经营情况介绍 | | | | 经营业绩情况： | | | 投资者关系活 | 2025 年 1-6 | 月，公司实现营业收入 484,236,510.36 元，较上 | | | 年 同 期 增 长 12.81% | ； 实 现 归 属 于 上 市 公 司 股 东 的 净 利 润 | | 动主要内容介 绍 | 177,008,721.63 | 元，较上年同 ...

Investment Rating - The report does not explicitly state an investment rating for the industry, but it provides insights into market performance and trends [2][4]. Core Insights - The pharmaceutical and biotechnology sector saw a weekly increase of 1.9%, underperforming the Wind All A index (2.21%) but outperforming the CSI 300 index [2][7]. - The medical research outsourcing segment experienced the highest growth at 8.29%, while chemical preparations and other biological products faced declines of -2.02% and -0.58%, respectively [2][8]. - The Quark Health model achieved a significant milestone by passing the written assessment for chief physician in 12 core disciplines, marking a rapid development phase for medical AI models in China [2][11]. - State-owned equity funds are actively acquiring stakes in pharmaceutical companies, with notable transactions including the acquisition of Kanghua Biological and a significant stake in MicroPort Medical [2][11]. Summary by Sections Market Weekly Review - The pharmaceutical and biotechnology sector rose by 1.9% from July 21 to July 25, 2025, with medical research outsourcing leading the gains at 8.29% [2][7]. - Individual stocks such as Haitai Biological (46.9%), Zhendong Pharmaceutical (42.9%), and Saily Medical (31.7%) saw significant increases, while *ST Suwu (-22.3%) and Yong'an Pharmaceutical (-13.7%) faced notable declines [2][10]. Industry News and Key Company Announcements Important Industry Events - The National Medical Insurance Administration announced new measures to optimize drug procurement, emphasizing quality over lowest price and launching a nationwide drug price comparison tool [2][11]. Industry News - Shanghai Biopharmaceutical M&A Fund is set to acquire shares in MicroPort Medical, becoming a strategic shareholder [2][11]. - Kangfang Biologics' new indication application for Ivoris monoclonal antibody has been accepted by the National Medical Products Administration [2][11]. Company Announcements - WuXi Biologics reported a positive mid-year earnings forecast, expecting a 16% revenue increase and a 3.6% rise in gross margin [2][14]. - The Quark Health model's capabilities continue to align closely with human physicians, marking a significant advancement in AI healthcare applications [2][14]. - WuXi AppTec and other companies reported substantial revenue growth, with WuXi AppTec expecting over 60% growth in the first half of 2025 [2][14].

Group 1: Company Developments - Iwubio has completed a clinical trial for its "Artemisia pollen allergen sublingual drops," demonstrating long-term efficacy and safety for adult patients with allergic rhinitis, providing evidence for clinical long-term use [1] - The company reported a net profit of 166 million to 181 million yuan for the first half of the year, representing a year-on-year growth of 16.96% to 27.56% [3] - Iwubio's product sales include 455 million yuan for dust mite drops, 21.02 million yuan for Artemisia pollen drops, and 6.32 million yuan for skin prick solution, with respective year-on-year growth rates of 10.51%, 71.37%, and 104.38% [3] Group 2: Market Position and Strategy - Iwubio is a leading player in the domestic desensitization treatment market, focusing on the development of allergen products and expanding into stem cell and natural medicine research [3][4] - The company has established a strong R&D team to enhance its innovation capabilities and maintain its market leadership [4] - Iwubio is the only company in China with two approved sublingual allergen desensitization products, providing a competitive edge in the desensitization treatment field [4] Group 3: Industry Trends - The global allergy treatment market is projected to reach 31.07 billion USD by 2029, with a compound annual growth rate of 8.10% from 2024 to 2029 [2] - The increasing prevalence of allergic diseases poses significant public health challenges, necessitating effective prevention and treatment strategies [2][6] - Iwubio aims to become an international leader in the pharmaceutical industry while ensuring long-term development and returns for shareholders and employees [6]

Core Viewpoint - Iwubio is expected to achieve a net profit of 170 million to 185 million yuan in the first half of 2025, reflecting a year-on-year growth of 13.92% to 23.97% [2] Group 1: Financial Performance - The company anticipates a net profit attributable to shareholders of 166 million to 181 million yuan after excluding non-recurring gains and losses, representing a year-on-year increase of 16.96% to 27.56% [2] - Sales of dust mite drops reached 455 million yuan, showing a year-on-year growth of 10.51% [2] - Revenue from the new products, such as Artemisia pollen sublingual drops and skin prick solution, increased significantly, with sales of 21.02 million yuan and 6.32 million yuan, respectively, marking growth rates of 71.37% and 104.38% [2] Group 2: Product Strategy and Market Position - The company focuses on the diagnosis and treatment of allergic diseases, with a strong emphasis on market promotion leading to increased product penetration [2] - Iwubio has commercialized eight skin prick products and received approval for new products, enhancing its diagnostic product line to meet a broader range of allergen testing needs [3] - The company aims to consolidate its advantages in the allergic disease treatment sector and expand into complementary products, enhancing its comprehensive competitiveness in the market [3] Group 3: Marketing and Promotion - Iwubio is enhancing its academic promotion system targeting both doctors and patients, utilizing a combination of internal marketing teams and external professional promotion teams [4] - The overall promotion strategy is developed by the company and involves third-party organizations to conduct academic meetings and market research, improving doctors' awareness and proper use of desensitization treatments [4] Group 4: Future Developments - The company is strategically entering new major medical product areas, including stem cell therapies and natural drugs (antibiotics resistant to treatment), aiming to develop more innovative drugs for sustainable growth [5]

Performance Forecast - The company expects a net profit attributable to shareholders of 170 million to 185 million yuan, representing a year-on-year increase of 13.92% compared to 149.23 million yuan in the same period last year [1] - The net profit after deducting non-recurring gains and losses is projected to be between 165.5 million and 180.5 million yuan, reflecting a year-on-year growth of 16.96% to 27.56% compared to 141.50 million yuan last year [1] Sales Performance - The sales revenue from dust mite drops reached 454.66 million yuan, an increase of 10.51% year-on-year [1] - The sales revenue from Artemisia pollen sublingual drops was 21.02 million yuan, showing a significant growth of 71.37% compared to the previous year [1] - The sales revenue from skin prick solution was 6.33 million yuan, marking a substantial increase of 104.38% year-on-year [1] - The rapid growth in sales of Artemisia pollen sublingual drops and skin prick solution is attributed to the company's increased marketing efforts for these products [1]

Core Insights - Zhejiang Iwu Biological Technology Co., Ltd. has made significant progress in the field of allergic disease diagnostics with the approval of its "Dermatitis Diagnostic Patch 02" for clinical trials by the National Medical Products Administration [1][5] Group 1: Product Development - The "Dermatitis Diagnostic Patch 02" focuses on diagnosing three common allergens: Kathon, p-phenylenediamine, and formaldehyde, which are frequently encountered in daily life and are known to cause allergic contact dermatitis [4][6] - The clinical trial process will follow a rigorous drug development protocol, including Phase I, II, and III trials to assess safety, efficacy, and dosage [5][6] Group 2: Market Position and Impact - Iwu Biological is a leading domestic pharmaceutical company specializing in the research and innovation of allergic disease diagnostics and treatments, with a strong R&D team and a history of successful product launches [6][7] - The approval of the "Dermatitis Diagnostic Patch 02" is expected to enhance the company's competitiveness in the diagnostic market and contribute to the development of the allergic disease diagnostics sector in China [6][7]

Core Viewpoint - Iwubio has demonstrated steady growth in its financial performance, with a focus on innovation in the desensitization treatment sector, positioning itself as a leader in a competitive market [1] Group 1: Financial Performance - For the year 2024, Iwubio reported a revenue of 925 million yuan, representing a year-on-year growth of 9.10% [1] - The net profit attributable to shareholders was 318 million yuan, an increase of 2.46% year-on-year [1] - In Q1 2025, the company achieved a revenue of 228 million yuan, up 5.7% year-on-year, with a net profit of 74 million yuan, reflecting a growth of 1.5% [1] - Operating cash flow for Q1 2025 reached 85.88 million yuan, marking a significant increase of 96.2% [1] - Cumulatively, the company has distributed over 850 million yuan in cash dividends since its listing, which is approximately four times the amount raised during its IPO [1] Group 2: Competitive Advantages - Iwubio has established three competitive barriers: technological innovation, product scarcity, and industry leadership [2][3][4] - The company invested 125 million yuan in R&D in 2024, accounting for 13.48% of its revenue, which is above the industry average [2] - Iwubio's product "Dust Mite Drops" is the only sublingual desensitization treatment available in China, providing a significant advantage in terms of safety and convenience compared to subcutaneous alternatives [3] - The market share of Iwubio's "Dust Mite Drops" has consistently remained above 81.72%, confirming its leading position in the domestic desensitization treatment market [4] Group 3: Growth Potential - The allergy treatment market is expected to grow due to the increasing prevalence of allergic diseases, with reports indicating that around 40% of the Chinese population suffers from such conditions [5] - Iwubio's "Dust Mite Drops" and "Artemisia Pollen Sublingual Drops" have shown significant growth, with the latter achieving a 76.43% increase in 2024 [5] - The company is expanding its product offerings in the allergy testing market, with new products like "Pollen Skin Prick Test Solutions" receiving market approval [5] - Iwubio is also venturing into stem cell therapies and natural medicines, aiming to create a second growth curve [6] - The company has identified a drug molecule for antibiotic-resistant tuberculosis and is advancing its clinical research [6] Group 4: Strategic Outlook - Iwubio's strategic positioning in the allergy treatment sector, combined with its innovative approaches in stem cell and natural medicine, suggests a robust growth trajectory [7] - The company is well-positioned to navigate the evolving pharmaceutical landscape, focusing on both maintaining its core allergy treatment business and exploring new therapeutic areas [7]

Group 1: Market Competition and Product Strategy - The domestic allergy treatment market growth has slowed to 8%, with competitors like Novartis and ALK accelerating sublingual desensitization therapy [1] - The company has three dust mite desensitization drugs approved for nationwide sale, including its own "Dust Mite Drops" [1] - The company is not concerned about competition, believing that more participants can help expand the market [1] Group 2: Cost Structure and Financial Management - The company's main product costs remained stable in 2024, with a high gross margin [2] - Future cost optimization will focus on external procurement and production planning, although the potential for significant cost reduction is limited due to high margins [2] - The company has entrusted financial management with an amount of 206.5 million yuan, with an unexpired balance of 194.838 million yuan [2] Group 3: Research and Development Focus - The company is developing new major medical products, including stem cell therapies and natural drugs (anti-drug-resistant antibiotics) [2][4] - Current R&D investments are primarily focused on allergen products, with plans to enter new medical fields [4] - New drug development cycles are long and risky, making it difficult to predict product launch timelines [4] Group 4: Industry Standards and Regulatory Compliance - The company has established its own drug registration standards, which have been approved by the National Medical Products Administration [4] - Participation in industry standard formulation enhances the company's influence and competitiveness in the allergy treatment sector [4]