前段时间，韩国总统李在明"将脱发治疗纳入医保"的提议火了。调侃之余，人们也意识到，脱发问题不只是容貌焦虑带来的社会压力。现代人 的生活作息、饮食习惯以及高压的精神状态，都会导致脱发。或许，随着年龄增长，我们每个人都将学习如何与头发（或者脱发）相处。 尽管这个提案遭到了大量来自医学人士和保守派的强烈反对，但某种程度上也折射出脱发问题在韩国日益水深火热。根据韩国国家健康保险服务局的统 计，2024年韩国因脱发就医的24万人中，40%来自20多岁和30多岁的年龄段。也就是说，脱发的情况越来越多地发生在年轻人身上了。 可是，脱发何曾饶过谁？放眼世界，"越来越秃"是一大趋势，全球范围内庞大的脱发治疗市场也应运而生。 脱发焦虑，数韩国最强 在2024年大热的韩国现实主义电视剧《好久没做》里，有这么一幕，男女主正在讨论为什么结婚几年后很难再有生理反应了，这时候安宰贤扮演的男主突 然来了一句："是不是因为我吃了脱发药的缘故？" 表面看头发并不少的男主，竟然也在偷偷服用治脱发的药物，看来脱发确实是具有国民关心度的问题。 治疗脱发药物确实有副作用。（图/《好久没做》） "如果大韩民国3名以上中年男性聚在一起，对话大体上可以概括为 ...

Core Insights - The article discusses the competitive landscape of the hair medical industry in China, highlighting key players and market dynamics [1][5]. Group 1: Competitive Landscape - The Chinese hair medical industry features various competitive factions, with companies like Yonghe Medical, Damaik, and Qingyi focusing on hair transplant medical services, while SanSheng Pharmaceutical, Zhendong Pharmaceutical, and Xianju Pharmaceutical are involved in medical nurturing services [1]. - In the hair transplant sector, the first tier consists of leading national chain brands such as Yonghe Medical, Bilian Sheng, and Damaik, which collectively hold a significant market share and possess nationwide direct chain layouts, mature technology systems, and strong brand recognition [1]. Group 2: Hair Growth Pharmaceuticals - In the hair growth pharmaceuticals market, the first tier includes SanSheng Pharmaceutical, Zhendong Pharmaceutical, and Merck, with the former two holding major shares in the minoxidil market, while Merck is recognized as the original manufacturer of finasteride [5]. - The second tier comprises Xianju Pharmaceutical, Kang En Bei, and Xiamen Meishang Pharmaceutical, which have accelerated the launch of minoxidil and finasteride products in recent years, gaining notable market recognition [5]. Group 3: Sales Performance - In the online pharmacy sector, Zhejiang SanSheng's minoxidil tincture product achieved sales exceeding 1 billion yuan, while Zhendong Anxin's minoxidil lotion surpassed 300 million yuan in sales, and SanSheng's minoxidil foam also exceeded 100 million yuan [9]. - In the offline market during the first quarter of 2025, Zhejiang SanSheng's minoxidil tincture and Zhendong Anxin's minoxidil lotion both recorded sales above 20 million yuan, with market shares of 50.61% and 38.82%, respectively [10]. - The sales ranking for minoxidil products shows Zhejiang SanSheng's minoxidil tincture leading with over 34 million yuan in sales (50.61% market share), followed by Zhendong Anxin's minoxidil lotion with over 26 million yuan (38.82% market share) [11].

Core Insights - Cosmo has achieved a significant breakthrough in the treatment of androgenetic alopecia (AGA) with the positive results of Clascoterone 5% topical solution in two Phase 3 clinical trials, showing a 539% improvement in hair count compared to placebo, leading to a 20% increase in Cosmo's stock price [1][11] - The global market for hair loss treatments is substantial, with a projected size of €28 billion (approximately ¥230.5 billion), driven by a large and growing patient population and a lack of effective and safe new mechanism drugs [7][8] Group 1: Treatment Mechanism and Market Demand - AGA affects approximately 30% of the male population, with prevalence increasing with age, particularly among men aged 40-49, where 53% experience moderate to severe hair loss [2] - Current treatments like minoxidil and finasteride have limitations; minoxidil is not specifically designed for AGA and has side effects, while finasteride's systemic hormonal interventions can lead to significant side effects, deterring many patients [5][6] - Clascoterone 5% offers a localized treatment approach that effectively blocks DHT receptors in hair follicles without systemic side effects, marking a potential shift in AGA treatment paradigms [3][4] Group 2: Clinical and Commercial Viability - Clascoterone's clinical success is built on the established market presence of Winlevi, a 1% concentration acne treatment that has seen over 1.3 million prescriptions since its launch in November 2021, demonstrating commercial viability and clinical promotion capabilities [7] - The urgency for effective hair loss treatments is underscored by patient willingness to invest significantly in solutions, with over 65% expressing deep concern about hair loss and more than 83% eager to try new treatments [9][10] Group 3: Innovation in Drug Development - Clascoterone's development exemplifies a trend in innovative drug research, where adjusting drug concentration and optimizing delivery methods can yield different therapeutic effects for various conditions [12][13] - This approach highlights the importance of understanding disease mechanisms and target validation, suggesting that non-structural innovations like Clascoterone will play a crucial role in the future of drug development [13]

Core Insights - The article emphasizes the importance of prostate health across different age groups, highlighting common misconceptions and the need for awareness and regular check-ups [1][5][9] Group 1: Prostate Health in Young Men (20+) - Prostatitis is often misunderstood as a sexually transmitted disease, but it is primarily linked to poor lifestyle habits [2] - Prolonged sitting, consumption of spicy food and alcohol, high stress levels, and infrequent urination can lead to prostatitis [3] - Symptoms of prostatitis include not only urinary issues but also pelvic pain and emotional disturbances, necessitating medical consultation for proper diagnosis and treatment [4] Group 2: Prostate Cancer Awareness (40+) - Prostate cancer is referred to as a "silent killer" due to its asymptomatic early stages, making PSA testing crucial for early detection [6] - Men with a family history of prostate cancer should start annual PSA tests and digital rectal exams at age 45, while average-risk men should begin at age 50 [7][8] Group 3: Prostate Enlargement in Older Men (70+) - Prostate enlargement is a natural part of aging, driven by hormonal changes, leading to urinary difficulties [9] - Management strategies for mild to moderate symptoms include lifestyle adjustments and medications, while severe cases may require minimally invasive surgical procedures [10]

Core Viewpoint - The article discusses the importance of prostate health across different age groups, emphasizing the need for awareness, early detection, and appropriate treatment methods for prostate-related issues in men. Group 1: Prostate Health in Young Men (20+) - Prostatitis is often misunderstood as a result of poor lifestyle choices rather than a sexually transmitted disease, with bad habits being the primary cause [2] - Prolonged sitting can compress the prostate, leading to poor blood circulation and inflammation; it is recommended to take breaks every hour [3] - Consumption of spicy foods and alcohol can cause blood vessel dilation in the pelvic area, exacerbating discomfort [4] - Stress and anxiety can lead to muscle spasms affecting the prostate, resulting in frequent urination despite low fluid intake [5] - Insufficient water intake and holding urine can lead to concentrated urine irritating the prostate; symptoms may include pain in the perineum and lower back [6] Group 2: Prostate Health in Middle-Aged Men (40+) - Prostate cancer is often referred to as a "silent killer" due to its asymptomatic early stages; regular PSA testing is crucial for early detection [7][9] - PSA tests and B-scan ultrasounds serve different purposes; PSA levels indicate internal prostate health, while B-scan assesses external changes [8] - Men with a family history of prostate cancer should start annual PSA testing and digital rectal exams at age 45, while others should begin at 50 [9] Group 3: Prostate Health in Older Men (70+) - Benign prostatic hyperplasia (BPH) is a common condition in older men, resulting from hormonal changes that cause prostate enlargement [10] - Mild symptoms can often be managed through lifestyle adjustments, such as reducing fluid intake before bed and avoiding diuretics [11] - Moderate symptoms may require medication like alpha-blockers to relax prostate muscles, while severe cases may necessitate minimally invasive surgical procedures [12]

Core Viewpoint - The "Chronic Disease Prevention and Treatment in China" academic conference held on May 18 highlighted the significant advancements in the treatment of prostate diseases, particularly through the innovative use of Xia Li Qi capsules, which have shown promising results in alleviating lower urinary tract symptoms (LUTS) associated with prostate conditions [1][3][4] Group 1: Prostate Disease Prevalence and Impact - Prostate diseases, such as benign prostatic hyperplasia (BPH), have a high incidence rate that severely affects male health, with approximately 20% of men aged 51-60, 50% of those aged 61-70, and 83% of men aged 81-90 being affected [3] - LUTS are common among BPH patients, with 90% of men aged 45-80 experiencing these symptoms, which include urinary frequency, urgency, incontinence, and nocturia [3] Group 2: Treatment Approaches and Innovations - For patients without surgical indications, the primary treatment for LUTS is medication; however, current conventional Western medications have limitations in safety and efficacy, necessitating better treatment options [3] - Xia Li Qi capsules, guided by the theory of "Luo Disease," combine "promoting, supplementing, and transforming" principles, offering advantages over traditional heat-clearing and dampness-dispelling methods [3][4] Group 3: Clinical Research and Efficacy - Research indicates that Xia Li Qi capsules significantly improve LUTS, delay disease progression, and enhance patients' quality of life, demonstrating good safety profiles [4] - Clinical studies confirm that Xia Li Qi capsules can reduce the International Prostate Symptom Score (IPSS) and improve urinary flow rates, with additional benefits when combined with medications like Tamsulosin and Finasteride [4] - Xia Li Qi capsules are classified as a Category B drug under medical insurance and are recommended in various clinical guidelines, providing new treatment options for prostate disease patients [4]