Key Takeaways J&J will report third-quarter 2025 results on Oct. 14, kicking off the earnings season for pharma players.Sales growth is expected from Darzalex, Tremfya, Erleada and new drugs like Carvykti and Tecvayli.Stelara faces steep biosimilar competition, while MedTech faces China-related headwinds.Johnson & Johnson (JNJ) will begin the earnings season for the drug & biotech sector when it reports its third-quarter 2025 results on Oct. 14. The Zacks Consensus Estimate for third-quarter sales and earni ...

Key Takeaways J&J projects stronger Innovative Medicine sales in H2 despite Stelara's LOE.Higher demand for Darzalex, Tremfya, and Erleada likely supported segment growth in Q3.Stelara biosimilars and IRA's Part D redesign continue to put pressure on J&J's drug sales.Johnson & Johnson (JNJ) , through its Innovative Medicine division, markets several blockbuster drugs across diverse therapeutic areas, including neuroscience, cardiovascular and metabolism, immunology, oncology, pulmonary hypertension (PH), an ...

Industry Overview - The global cancer treatment market is experiencing rapid growth due to rising cancer incidence, an aging population, and increasing demand for safer, more effective therapies, with over 2 million new cancer cases and 618,000 related deaths projected in the U.S. for 2025 [1] - Breakthroughs in immunotherapy, targeted treatments, and personalized cancer vaccines are reshaping the oncology landscape, offering greater precision and improved outcomes [2] - The oncology market is poised for robust, long-term growth, presenting compelling opportunities for investors [4] Major Companies and Developments - Major pharmaceutical companies such as Novartis, AstraZeneca, Johnson & Johnson, Pfizer, AbbVie, Bristol Myers Squibb, and Eli Lilly are heavily investing in advanced approaches like antibody-drug conjugates and immuno-oncology agents, while smaller biotechs are driving innovation and becoming attractive acquisition targets [3] - Johnson & Johnson's oncology segment accounts for approximately 27% of its total revenues, with oncology sales rising 22.3% to $6.3 billion in Q2 2025, driven by strong market growth and key product share gains [6] - Johnson & Johnson expects its oncology sales to reach $50 billion by the end of the decade, citing strong growth in marketed cancer drugs and the potential of upcoming launches [7] - Novartis has a diverse oncology portfolio, with significant contributions from drugs like Kisqali, which recorded sales of $1.1 billion in Q2 2025, up 64% year over year [9][10] - Novartis' oncology sales rose 20% in constant currency terms to $4.3 billion in Q2 2025, bolstered by new drug approvals and acquisitions [10] Emerging Companies and Innovations - Allogene Therapeutics is focused on developing allogeneic CAR T therapies for cancer treatment, particularly in hematologic indications with high unmet needs [11] - Allogene Therapeutics has multiple clinical-stage pipeline candidates, including cema-cel for large B-cell lymphoma and ALLO-316 for advanced renal cell carcinoma, showing promising early anti-tumor activity [12][13]

Recent Developments Related to JNJ's Rybrevant J&J (JNJ) recently reported new positive data from the phase III MARIPOSA study, which compared the combination of Rybrevant and Lazcluze against AstraZeneca's (AZN) Tagrisso in first-line EGFR-mutated non-small cell lung cancer ("NSCLC"). Data from the study suggests that the Rybrevant-Lazcluze combo significantly extends overall survival ("OS") in NSCLC patients with EGFR exon 19 deletions (ex19del) or exon 21 L858R substitution (L858R) mutations. At a median ...