在全球，大概每10个育龄女性中就有1个饱受子宫内膜异位症的折磨——这是一种影响约1.9亿女性的高 发疾病，90%的患者经历着间断性的盆腔疼痛，26%甚至面临不孕的阴影。 然而，当Organon近日宣布其"明星候选药物"OG-6219在二期临床试验中宣告失败时，这个本应充满希 望的领域再次被蒙上阴霾。 OG-6219曾被寄予厚望，被Organon视为"重塑痛经治疗标准"的突破，但它的失败不仅让Organon的女性 健康创新管线陷入危机，更揭示了子宫内膜异位症药物研发的深层困境： 一个影响数亿人的市场，为何新药寥寥无几？痛经药物的春天究竟何时才能到来？ 01 需求巨大，供给稀缺 痛经，尤其严重的痛经，很可能是一种病——子宫内膜异位症。子宫内膜异位症远不止痛经那么简单， 不仅可以侵袭周围组织和其他器官，导致复杂的症状，还容易在治疗后反复发作，直到绝经后才能缓 解，给患者带来无尽的痛苦折磨。 理论上，子宫内膜异位症拥有巨大的治疗需求与商业空间，但现实却是新药稀缺，研发缓慢。 更早前，拜耳也曾布局这一领域，其靶向孕激素/催乳素（ER/PR）药物Visanne于2010年首次在欧洲获 批，用于治疗子宫内膜异位症引发的疼痛 ...

Deckers Outdoor Corporation (NYSE: DECK ) designs, markets, and distributes premium footwear and apparel brands including UGG, HOKA, Teva, and Sanuk, with the first two being the main drivers of sales. The company has delivered impressive growth driven by an explosive gain in popularity of HOKA andHi! I'm a passionate investor who has been researching publically traded companies for over 6 years. My primary focus is on identifying great businesses at reasonable prices and holding them for the long term. Whi ...

Iconic Burger Chain Celebrates National French Fry Day All Week-Long with Free Fat or Skinny Fries with Online Purchase LOS ANGELES, July 07, 2025 (GLOBE NEWSWIRE) -- Fatburger, the all-American burger chain owned by FAT Brands Inc., is ringing in National French Fry Day with a week-long golden, crispy and perfectly salted deal! From July 9 through July 13 at participating locations, fans can get their hands on a free order of Fat or Skinny Fries with any burger or sandwich purchase made online through www. ...

Core Viewpoint - The private sector is experiencing job losses, which is beneficial for earnings season and dividend growth stocks due to easing wage pressures and lower inflation, leading to better profit margins and dividend hikes [2]. Dividend Growth Stocks Dividend Growth Stock 1: T-Mobile US (TMUS) - T-Mobile US initiated a new dividend program in 2023 and raised its dividend by 35% to 88 cents per share after merging with Sprint [6][8]. - The company is expanding its margins and free cash flow, which supports its dividend growth strategy [7][9]. Dividend Growth Stock 2: Amphenol (APH) - Amphenol has seen significant growth, particularly in AI-related applications, with total orders increasing by nearly 60% year-over-year in Q1 2025 [12]. - The company raised its dividend by 50% last year, marking one of its largest increases [12]. Dividend Growth Stock 3: California Resources (CRC) - California Resources has shifted towards green-energy initiatives and has increased its quarterly distribution by 128% since its initiation [15]. - The company has been profitable since emerging from bankruptcy in 2021 and has seen its shares triple since relisting [16]. Dividend Growth Stock 4: RLJ Lodging Trust (RLJ) - RLJ Lodging Trust reduced its dividend significantly during the pandemic but has since increased it by 1,400% from its low point [19]. - Analysts project a 40% AFFO payout ratio for RLJ, indicating potential for further dividend growth [20]. Dividend Growth Stock 5: Coca-Cola Consolidated (COKE) - Coca-Cola Consolidated has shown consistent top-line growth and recently announced a $16-per-share special dividend, along with a quintupled regular payout to $2.50 per share [24]. - The company currently pays out only 15% of its earnings as dividends, suggesting room for future increases [24].

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在企业发展战略上，东风日产将继续坚持"双线并进"的路径：一方面巩固燃油车的市场根基，另一方面 加速布局新能源赛道。副总经理高政浩表示，东风日产将在燃油车领域保持领先地位，同时稳步推进电 动化转型。 7月2日，东风日产正式推出全新奇骏·荣誉车型，共计两款，官方指导价分别为16.08万元和16.68万元， 限时诚意价下探至11.98万元与12.58万元，性价比显著提升。 据东风日产汽车销售有限公司总经理刘新宇介绍，此次新车升级广泛吸纳用户反馈，在科技配置、内部 空间和外观设计等方面全面优化。作为日产全球战略车型，奇骏基于CMF平台打造专业级SUV底盘， 搭载Nissan Connect超智联2.0+系统，实现语音控制、远程监测、远程启停等智能功能，软硬件协同升 级，科技感显著提升。 在产品开发方面，日产计划大幅缩短研发周期：首款车型开发周期将压缩至37个月，家族化车型进一步 缩短至30个月。尤其针对中国市场，研发周期将缩减至24个月，并在保证品质与安全的前提下加快产品 迭代。同时，日产将通过70%的零部件复杂度削减、平台架构整合等手段，到2035财年将平台数量从13 个压缩至7个。 在销量表现方面，日产汽车在中国 ...

'Do they have gold in them?': The Indian artisans up in arms over Prada's sandals https://t.co/tAWUy6QDLI ...

Since sandals can present a sartorial minefield—some plunder wallets, others murder feet and plenty more wound eyeballs—it is worth keeping a few things in mind. Our seven rules to follow: https://t.co/vIzdiBFtcm ...