格隆汇12月9日丨迪哲医药(688192.SH)公布，公司在第67届美国临床血液学会（American Society of Hematology，ASH）大会上，公布了公司自主研发的两款全球首创新药的最新研究成果：高选择性 JAK1 抑制剂高瑞哲®（通用名：戈利昔替尼胶囊）在 T 细胞淋巴瘤领域取得多项新进展，以及非共价 LYN/BTK 双靶点抑制剂 birelentinib（DZD8586）在 B 细胞淋巴瘤治疗领域的最新临床数据。 ...

人民财讯12月9日电，迪哲医药(688192)12月9日公告，公司在第67届美国临床血液学会(ASH)大会上， 公布了公司自主研发的两款全球首创新药的最新研究成果：高选择性JAK1抑制剂高瑞哲(通用名：戈利 昔替尼胶囊)在T细胞淋巴瘤领域取得多项新进展，以及非共价LYN/BTK双靶点抑制剂 birelentinib(DZD8586)在B细胞淋巴瘤治疗领域的最新临床数据。 ...

本次ASH大会，迪哲公布了该研究的最新随访数据。在III期推荐剂量(RP3D)50mg下，ORR为84.2%;在 既往接受过BTK抑制剂、Bcl-2抑制剂或BTK降解剂治疗，以及携带经典BTK耐药突变(C481X)或其他 BTK突变(包括激酶"失活"突变)的患者中均观察到肿瘤缓解;抗肿瘤疗效持久，且安全性良好，随访期间 未发现新的安全性问题。 迪哲医药(688192.SH)公告，公司第67届美国临床血液学会(ASH)大会上，公布了公司自主研发的两款全 球首创新药的最新研究成果：高选择性JAK1抑制剂高瑞哲(通用名：戈利昔替尼胶囊)在T细胞淋巴瘤领 域取得多项新进展，以及非共价LYN/BTK双靶点抑制剂birelentinib(DZD8586)在B细胞淋巴瘤治疗领域 的最新临床数据。 ...

本次ASH大会，迪哲公布了该研究的最新随访数据。在III期推荐剂量(RP3D)50mg下，ORR为84.2%;在 既往接受过BTK抑制剂、Bcl-2抑制剂或BTK降解剂治疗，以及携带经典BTK耐药突变(C481X)或其他 BTK突变(包括激酶"失活"突变)的患者中均观察到肿瘤缓解;抗肿瘤疗效持久，且安全性良好，随访期间 未发现新的安全性问题。 智通财经APP讯，迪哲医药(688192.SH)公告，公司第67届美国临床血液学会(ASH)大会上，公布了公司 自主研发的两款全球首创新药的最新研究成果：高选择性JAK1抑制剂高瑞哲®(通用名：戈利昔替尼胶 囊)在T细胞淋巴瘤领域取得多项新进展，以及非共价LYN/BTK双靶点抑制剂birelentinib(DZD8586)在B 细胞淋巴瘤治疗领域的最新临床数据。 ...

Core Viewpoint - Dize Pharmaceutical (688192) has experienced a decline in stock price, closing at 59.77 yuan, down 6.17% from the previous week, with a current market capitalization of 27.459 billion yuan, ranking 15th in the chemical pharmaceutical sector and 692nd in the A-share market [1] Group 1: Company Performance - For the first three quarters of 2025, the company achieved revenue of 586 million yuan, representing a year-on-year growth of 73% [5] - The company's core products, Shuwozhe (舒沃哲) and Gao Ruizhe (高瑞哲), have been successfully included in the national medical insurance directory, maintaining rapid growth post-inclusion [5][6] - The company is currently in a loss-making state but aims to expedite the launch of more products or indications to achieve profitability sooner [3] Group 2: Product Development and Market Position - Shuwozhe is the first and only domestically developed innovative drug approved in the U.S. for EGFR Exon20ins NSCLC, and it has been included in the NCCN guidelines for non-small cell lung cancer [4] - Gao Ruizhe is the first drug targeting the JAK/STAT pathway for peripheral T-cell lymphoma (PTCL), showing significant clinical benefits and the longest median overall survival (mOS) among single-agent treatments for relapsed/refractory PTCL [4] - The company has established a competitive clinical product pipeline with seven products, including Shuwozhe and Gao Ruizhe, which are expected to enhance the company's international standing in the innovative drug industry [4] Group 3: Research and Development Initiatives - The global registration clinical study "JCKPOT8 B part" for Gao Ruizhe has reached its primary research endpoint, and the company is actively validating the new drug application for overseas markets [3] - Birelentinib (DZD8586) has initiated a Phase III clinical study for relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), with active participant recruitment [3] - The company is assessing various overseas collaboration models for Shuwozhe, focusing on global commercialization capabilities and pipeline synergy [2]

Core Insights - DiZhe Pharmaceutical (688192) will present multiple latest research findings on its key lymphoma treatment products, Golixty (generic name: Golixty capsules) and Birelentinib (DZD8586), at the 67th American Society of Hematology (ASH) conference from December 6 to 9 [1] Group 1: Product Developments - The ASH conference will showcase Golixty's exploration and progress in monotherapy and combination therapy strategies for r/r PTCL, first-line treatment, and rare subtypes, highlighting its broad application potential in T-cell lymphoma treatment [1] - Birelentinib is a globally innovative non-covalent dual-target inhibitor of LYN/BTK that can fully penetrate the blood-brain barrier, with the latest data from I/II clinical studies in CLL/SLL patients previously treated with covalent or non-covalent BTK inhibitors and BTK degraders to be presented [1]

Core Viewpoint - The company, DIZHE Pharmaceutical (688192), will present multiple research findings on its key lymphoma treatment products, Golitinib (generic name: Golitinib capsules) and Birelentinib (DZD8586), at the 67th American Society of Hematology Annual Meeting from December 6 to 9 [1] Group 1 - The company has 15 abstracts accepted for presentation at the conference, highlighting its extensive pipeline and research potential in the field of hematologic oncology [1]

Core Viewpoint - The company, DIZHE Pharmaceutical (688192.SH), will present multiple research findings on its key lymphoma treatment products at the upcoming 67th American Society of Hematology (ASH) conference from December 6 to 9, showcasing its robust pipeline and research potential in the field of hematologic oncology [1] Group 1 - The company will unveil research results for two core products: Golitiximab (highly regarded as 高瑞哲®) and birelentinib (DZD8586) [1] - A total of 15 abstracts from the company have been accepted for presentation at the ASH conference, highlighting its extensive pipeline in blood cancer treatment [1] - The participation in this prestigious conference reflects the company's commitment to advancing research in hematologic malignancies [1]

Core Viewpoint - The company, DIZHE Pharmaceutical (688192.SH), will present significant research findings on its core lymphoma treatment products, Golixty (generic name: Golitinib capsules) and birelentinib (DZD8586), at the 67th American Society of Hematology (ASH) conference from December 6 to 9 [1] Group 1 - The company has 15 abstracts accepted for presentation at the ASH conference, highlighting its extensive pipeline and research potential in the field of hematologic oncology [1]

Core Insights - The company, DIZHE Pharmaceutical (688192.SH), will present multiple research findings on its core lymphoma treatment products, Golitinib (高瑞哲®) and birelentinib (DZD8586), at the 67th American Society of Hematology (ASH) conference from December 6 to 9 [1] - A total of 15 abstracts from the company have been accepted for the conference, highlighting its extensive pipeline and research potential in the field of hematologic oncology [1]