Investment Rating - The report does not specify a clear investment rating for the company [2]. Core Views - As of June 21, 2024, the company received a $75 million equity investment from Takeda, significantly boosting its cash reserves and supporting clinical research in China and the U.S. [2] - The company signed an exclusive option agreement for the global rights to the third-generation BCR-ABL inhibitor, Olverembatinib, outside of China, receiving an upfront payment of $100 million and potential milestone payments totaling up to $1.2 billion [2][3]. - The efficacy of Olverembatinib in patients previously treated with TKI therapies is notable, with a 60.8% complete cytogenetic response (CCyR) rate and a 42.4% major molecular response (MMR) rate, indicating a potential peak sales exceeding $1 billion overseas [3]. - The international progress of APG-2575, a Bcl-2 inhibitor, is accelerating, with multiple indications entering Phase III clinical trials, including a significant milestone with FDA approval for a global registration trial in chronic lymphocytic leukemia (CLL) [3]. - Revenue forecasts for the company are optimistic, with projected revenues of 1.07 billion, 620 million, and 1.18 billion yuan for 2024, 2025, and 2026, respectively, driven by the commercialization of Olverembatinib and APG-2575 [4][8]. Summary by Sections Financial Performance - The company reported revenues of 221.98 million yuan in 2023, with a projected increase to 1.07 billion yuan in 2024, followed by a decrease to 620.49 million yuan in 2025, and a rebound to 1.18 billion yuan in 2026 [4][9]. - The net profit attributable to the parent company is expected to improve from a loss of 925.64 million yuan in 2023 to a loss of 121.92 million yuan in 2024, and further losses of 560.18 million yuan in 2025, and 102.77 million yuan in 2026 [4][9]. - Earnings per share (EPS) are projected to improve from -2.94 yuan in 2023 to -0.39 yuan in 2024, -1.78 yuan in 2025, and -0.33 yuan in 2026 [4][9]. Market Position and Growth Potential - The company is expected to capture market shares of 13.9%, 28.9%, and 41% for Olverembatinib in the treatment of CML from 2024 to 2026, translating to revenues of 3.4 billion, 5.7 billion, and 9.7 billion yuan, respectively [8]. - APG-2575 is anticipated to generate revenues of 0.5 billion yuan in 2025 and 2.1 billion yuan in 2026, with market entry expected in 2025 [8]. Clinical Development - The report highlights the significant clinical efficacy of Olverembatinib, particularly in patients resistant to previous treatments, which supports the company's growth narrative [3]. - APG-2575's entry into critical registration trials marks a significant milestone in the company's international expansion efforts [3].

[Tabl 2024e_StockInfo 年 06 月 24 日] 证券研究报告•公司研究报告 买入 (首次) 当前价:7.07 港元 龙源电力(0916.HK)公用事业 目标价:8.52 港元 风电龙头装机高增,"以大代小"提升效率 推荐逻辑:1)国务院多举措助力绿电消纳,未来价格机制完善有望保证绿电企 业合理收益;2)资源储备充足,2024-2025 年或迎来投产高峰,分别投产 7.5GW 和 11.5GW,国能集团 21.4GW 新能源资产有望注入;3)发电量平稳增长,"以 大代小"有利于提升运营效率。 多举措助力绿电消纳,价格机制有望完善。国务院印发《2024-2025 年节能降 碳行动方案》,采取多项举措助力绿电消纳。近年来特高压建设提速,预计 2024 年线路长度超过 5万公里,储能装机容量高增,政策目标到 2027年抽蓄投运规 模达到 8000万千瓦以上,需求侧响应能力达到最大负荷的 5%以上,消纳能力 持续改善。新能源入市交易大势所趋,价格机制有望进一步完善,以保障绿电 企业合理收益。同时绿电环境价值逐步凸显,国家电网公司经营区成交绿电的 环境溢价呈现逐年提升。 装机量保持高增,资源分布优质 ...

Investment Rating - The report maintains an "Outperform" rating for the automotive industry as of June 23, 2024 [1]. Core Insights - The report highlights that the penetration rate of new energy vehicles (NEVs) is expected to reach 49.1% in June, with a projected retail volume of approximately 860,000 NEVs, reflecting a month-on-month increase of 6.9% [2]. - The report emphasizes the potential for growth in the smart vehicle sector, driven by government policies and technological advancements [2]. - The report suggests that the automotive market is likely to see increased sales due to the implementation of vehicle replacement subsidies and manufacturers striving to meet semi-annual sales targets [2]. Summary by Sections 1. Market Review - The SW automotive sector index rose by 0.3% last week, while the CSI 300 index fell by 1.3%. The passenger vehicle sector increased by 2.1%, and the commercial passenger vehicle sector surged by 7.8% [7]. 2. Market Highlights 2.1 Industry News - In the first half of June, wholesale passenger vehicle sales were 619,000 units, down 20% year-on-year, while retail sales were 634,000 units, down 13% year-on-year [24]. - The National Development and Reform Commission (NDRC) expressed strong opposition to the EU's proposed tariffs on Chinese electric vehicles, emphasizing the need for fair competition [24]. - The NDRC announced plans to enhance charging infrastructure, focusing on network optimization and service improvement [25]. 2.2 Company News - Major companies such as GAC Group and BYD are highlighted for their performance, with BYD's passenger vehicle sales reaching 330,000 units in May, a year-on-year increase of 38.2% [27]. - Dongfeng Motor signed a cooperation agreement with Guangxi to develop the new energy vehicle industry [25]. 2.3 New Vehicle Launches - Several new models were launched, including the Wuling Bingo and Hongqi H6, with prices ranging from 5.68 to 59.98 million yuan [30]. 2.4 International Sales Data - In North America, vehicle sales in May totaled 166.2 million units, reflecting a year-on-year increase of 4.9% [32]. 3. Investment Recommendations - The report recommends focusing on companies like BYD and GAC Group, which are well-positioned to benefit from policy changes and market trends [2].

Investment Rating - The report maintains an "Outperform" rating for the pharmaceutical industry as of June 23, 2024 [1]. Core Insights - The innovation drug sector in both A-shares and Hong Kong stocks experienced a decline, with A-shares down 4.32% and Hong Kong stocks down 5.88% in the fourth week of June 2024 [2][15]. - The report highlights that 14 stocks rose while 45 stocks fell in the innovation drug sector during the same week, with notable gainers including Frontline Bio-U (+15.82%) and Nanjing New Pharmaceutical (+8.85%) [2][15]. - Over the past six months, A-shares in the innovation drug sector have cumulatively decreased by 4.40%, underperforming the CSI 300 index by 7.44 percentage points [2][16]. - The report also notes that the XBI index in the U.S. increased by 2.21% during the same week, with a cumulative increase of 1.7% over the past six months [2][20]. Summary by Sections 1. Market Performance - A total of 14 stocks in the innovation drug sector rose, while 45 fell, with the A-share innovation drug sector down 4.32% [2][15]. - The Hong Kong innovation drug sector fell by 5.88%, underperforming the Hang Seng Index by 6.36 percentage points [2][18]. - The XBI index in the U.S. rose by 2.21% during the week [2][20]. 2. New Drug Approvals - In June, 7 new drugs were approved in China, with 3 new indications approved this week [3][21]. - The U.S. saw 5 NDA approvals and 1 BLA approval in June, with 2 NDA approvals and 1 BLA approval this week [3][26]. - No new drugs were approved in Europe or Japan during June [3][28][30]. 3. Key Drug Developments - The report discusses the progress of key innovative drugs, including the approval of lenacapavir for HIV-1 prevention, which showed a 100% efficacy rate in a key trial [4]. - The report also highlights the ongoing development of GLP-1 receptor agonists for diabetes and obesity, with multiple drugs in various stages of clinical trials [8][11]. 4. Clinical Trials - A total of 54 clinical trials were publicly announced in China this week, including 22 Phase I trials, 10 Phase II trials, and 21 Phase III trials [21][24].

Investment Rating - The report maintains a "Market Perform" rating for the media industry as of June 23, 2024 [1]. Core Insights - The media sector experienced a decline of 5.12% this week, underperforming the ChiNext by approximately 3.14 percentage points, while outperforming the CSI 300 by about 3.83 percentage points [7]. - The gaming index (CI005577) fell by 6.27%, while the advertising index (CI005847) decreased by 2.59% [8][10]. - The education index (CI005816) dropped by 2.92%, underperforming the CSI 300 by 1.62% [11]. Summary by Sections 1. Market Review - The media sector's performance was generally weak, with a 5.12% decline [7]. - The gaming index underperformed the market, with a 6.27% drop compared to the CSI 300's 1.30% decline [8]. - The advertising index also fell, down 2.59% [10]. 2. Gaming Industry - The top ten games on the iOS revenue chart include "Dungeon & Fighter: Origin," "Peacekeeper Elite," and "Honor of Kings" [28]. - The report highlights the successful launch of the SLG mobile game "Three Kingdoms: Strategize the World," which ranked high on the revenue charts [32]. 3. Sports Industry - The sports index (399804) decreased by 3.85%, underperforming the CSI 300 by 2.55% [10]. 4. Education Industry - The education index in A-shares fell by 2.92%, while the Hong Kong education index dropped by 4.78% [11]. - The report notes the performance of various education companies, with A-share companies underperforming the CSI 300 [13]. 5. Investment Recommendations - The report suggests focusing on companies such as Mango Super Media (300413) and Shenzhou Taiyue (300002) for potential investment opportunities [2].

Group 1 - The overall performance of the North Exchange was relatively weak during the week, with the North Exchange 50 index declining by 1.9% from the opening on June 17, 2024, and the total market capitalization reaching 318.84 billion yuan [20][63]. - The North Exchange's trading volume for the week was 16.72 billion yuan, with an average weekly trading amount of 0.67 billion yuan and a turnover rate of 15.39%, indicating a slight increase in liquidity compared to the previous week [2][6][31]. - The North Exchange is seen as a gathering place for "specialized, refined, distinctive, and innovative" enterprises, with a positive long-term outlook for its development, suggesting that more patient capital is expected to enter the market [1]. Group 2 - The North Exchange has resumed IPO activities, with two companies passing the listing committee review and three companies' applications being accepted within a week [3][19][55]. - The average market capitalization of companies in the North Exchange is 1.28 billion yuan, significantly lower than the average market capitalization of 7.27 billion yuan for the ChiNext and 9.49 billion yuan for the Sci-Tech Innovation Board [2][31]. - The North Exchange's price-to-earnings (PE) ratio (TTM, median) is 19.0 times, which has increased by 0.5 times compared to the previous week [2][31]. Group 3 - Among the 249 stocks in the North Exchange, 149 stocks increased, 3 remained flat, and 97 stocks decreased during the week, with Lifan Holdings seeing a significant increase of 77.8% [36][40]. - The machinery equipment industry performed relatively well, with a median increase of 10.4%, while the automotive industry showed a median decrease of -5.5% [40]

Investment Rating - The report maintains an "Outperform" rating for the pharmaceutical industry, indicating a positive outlook compared to the broader market [1]. Core Insights - The report highlights a significant decline in the A-share and Hong Kong innovation drug sectors, with A-shares down 4.32% and Hong Kong shares down 5.88% in the latest week, underperforming their respective indices [2][19]. - Over the past six months, A-share innovation drugs have decreased by 4.40%, while Hong Kong innovation drugs have seen a cumulative decline of 7.26% [17][19]. - The report notes that 7 new drugs were approved in China in June, with 3 new indications also receiving approval [3][23]. Summary by Sections Market Performance - In the latest week, 14 stocks in the innovation drug sector rose, while 45 fell, with the top gainers being Frontline Bio-U (+15.82%), Nanxin Pharmaceutical (+8.85%), and Ascentage Pharma-B (+7.59%) [2][16]. - The XBI index increased by 2.21% in the same week, contrasting with the declines in A-share and Hong Kong markets [21]. Drug Approvals - In June, 5 NDA approvals were granted in the U.S., with 2 NDA approvals and 1 BLA approval in the latest week [28]. - No new drugs were approved in Europe or Japan during June [30][32]. Key Drug Developments - The report discusses the progress of innovative drugs targeting GLP-1 for diabetes, with 11 drugs approved globally, 9 in China, and 10 in Phase III clinical trials [9][10]. - The report also covers the advancements in HIV-1 capsid inhibitors, particularly lenacapavir, which has shown a 100% efficacy rate in preventing HIV infection in women with biannual injections [4]. Company-Specific Developments - Notable approvals include the launch of new drugs by companies such as Amgen, Novartis, and others, with specific indications for various cancers and chronic conditions [24][25][35].

Investment Rating - The report maintains a "Market Perform" rating for the media industry [1]. Core Insights - The media sector experienced a decline of 5.12% this week, underperforming the ChiNext by approximately 3.14 percentage points and outperforming the market by about 3.83 percentage points compared to the CSI 300, which fell by 1.30% [7][8]. - The gaming index underperformed the market, with the CITIC Gaming Index down 6.27% compared to the CSI 300's 1.30% decline [8][10]. - The report suggests focusing on companies like Mango Excellent Media (300413) and Shenzhou Taiyue (300002) for investment opportunities [2][12]. Summary by Sections 1. Market Review - The media sector's performance was generally weak, with a 5.12% drop this week [7]. - The CITIC Advertising Index fell by 2.59%, while the CITIC Education Index decreased by 2.92% [12][10]. 2. Gaming Industry - The CITIC Gaming Index decreased by 6.27%, underperforming the CSI 300 [8]. - The top three A-share gaming companies by decline were Glacier Network, Shenzhou Taiyue, and Youzu Network [8][10]. 3. Sports Industry - The CSI Sports Index dropped by 3.85%, underperforming the CSI 300 [10]. 4. Education Industry - The CITIC Education Index fell by 2.92%, underperforming the CSI 300 by 1.62% [12]. - The Hong Kong Education Index decreased by 4.78%, while the Hang Seng Index rose by 0.48% [12]. 5. Investment Recommendations - The report recommends focusing on Mango Excellent Media (300413) and Shenzhou Taiyue (300002) for potential investment opportunities [2][12].

预计 6月新能源渗透率达 49.1%,智能汽车或将迎来β向上 投资要点 西南证券研究发展中心 行情回顾: 上周,SW 汽车板块上涨 0.3%,沪深 300下跌 1.3%。估值上,截 止 6 月 21 日收盘,汽车行业 PE(TTM)为 20 倍,较前一周下跌 0.3%。 投资建议:乘联会预计,6 月狭义乘用车零售量约 175.0 万辆,环比+2.3%; 预计新能源乘用车零售量约 86.0万辆,环比+6.9%,新能源渗透率将达 49.1%。 近期,发改委发言人提出国家将从优化完善网络布局、提升运营服务水平、加 强科技创新引领、加大支持保障力度方面进一步推动解决充电基础设施方面存 在的问题,新能源渗透率有望再创新高。此外,"车路云一体化"持续迎来政 策加码,智能汽车板块或将迎来β向上。投资机会方面,建议关注欧盟政策调 整给比亚迪等对欧洲有布局的主机厂带来的海外新机遇;建议关注政策变化给 智能汽车板块带来的机会;此外,建议关注气价持续低位振荡给天然气重卡板 块带来的机会以及《交通运输大规模设备更新行动方案》政策出台带来的重卡 置换需求释放机会。 乘用车:乘联会数据,6月 1-16日乘用车零售 63.4万辆,同比-1 ...

用电需求持续强劲,水电增速加快 本周 秦皇岛动力煤价较为稳定,预计后期逐渐企稳。截至 6 月 21 日,秦皇岛 Q5500 动力煤价格为 875元/吨,周环比下降 1.1%。截至 2024年 6月 13日, 全国重点电厂煤炭库存为 11557万吨,周环比库存增加 48万吨,增幅达 0.4%, 库存可用天数为 28.3 天,同比增长 2.5 天;6 月 17 日,CCTD 北方港口库存 为 3436 万吨,周环比库存增加 106 万吨,增幅达 3.2%。 用电需求持续强劲,水电增速加快。5 月份,全社会用电量 7751 亿千瓦时, 同比+7.2%,环比+0.2pp。从分产业用电看,第一/二/三产业用电量同比分别 +10.3%/+6.8%/+9.9%,环比分别-0.2/+0.6/-0.9pp,城乡居民生活用电量同比 +5.5%,环比-0.4pp;规上工业发电量 7179亿千瓦时,同比+2.3%,环比-0.8pp; 分品类看,火电同比-4.3%,环比-5.6pp;水电+38.6%,环比+17.6pp;核电 -2.4%,环比-8.3pp;风电-3.3%,环比+5.1pp;光伏发电+29.1%,环比+7.7pp。 本周 ...