（股份代號：1276） 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容而產生或因依賴 該等內容而引致的任何損失承擔任何責任。 Jiangsu Hengrui Pharmaceuticals Co., Ltd. 江蘇恒瑞醫藥股份有限公司 （於中華人民共和國註冊成立的股份有限公司） 董事會會議通告 江蘇恒瑞醫藥股份有限公司（「本公司」）董事會（「董事會」）謹此宣佈，董事會會 議將於2025年10月27日（星期一）舉行，藉以（其中包括）考慮及批准本公司及其 附屬公司截至2025年9月30日止九個月的季度業績及其發佈。 承董事會命 江蘇恒瑞醫藥股份有限公司 董事長 孫飄揚先生 中國上海 2025年10月13日 於本公告日期，董事會成員包括(i)執行董事孫飄揚先生、戴洪斌先生、馮佶女 士、張連山先生、江寧軍先生及孫杰平先生；(ii)非執行董事郭叢照女士；及(iii) 獨立非執行董事董家鴻先生、曾慶生先生、孫金雲先生及周紀恩先生。 ...

Summary of Hengrui Pharmaceuticals Conference Call Company Overview - **Company**: Hengrui Pharmaceuticals - **Industry**: Pharmaceuticals - **Market Cap**: RMB 474.9 billion - **Ticker**: 600276 CH - **Current Price**: RMB 71.55 - **Price Target**: RMB 86.00 (+20% upside) [7][10] Key Takeaways 1. Global Strategy and Partnerships - Hengrui's ex-China strategy aims to maximize asset value through out-licensing and equity-linked NewCo structures, exemplified by the collaboration with GSK, which includes multi-asset components and a 30% equity stake in NewCo [2][19] - The company is leveraging partnerships with multinational corporations (MNCs) like GSK and Merck to enhance its global reach while maintaining control over development and commercialization [2][21] 2. Pipeline Development - Hengrui is focusing on core therapeutic areas: oncology, metabolic/cardiovascular, immunology/respiratory, and neurology, with significant emphasis on metabolic innovation [3][25] - Key programs include dual and triple agonists, oral GLP-1 small molecules, and injectable peptides aimed at treating obesity and diabetes [3][22] 3. Financial Performance and Business Development - In 2025, Hengrui executed high-value business development deals, generating RMB 2 billion in income in the first half, leading to a margin expansion to 86.6% [4][10] - The company targets a 25% CAGR for innovative drugs over three years, showcasing disciplined capital allocation and strategic optionality [4][10] 4. Market Dynamics in China - China's evolving market, supported by government incentives and emerging commercial insurance models, is expected to drive growth and expand access to innovative therapies [5][27] - Hengrui anticipates sustained margin expansion as its portfolio transitions from generics to innovative products, particularly in obesity and cardiovascular markets [5][30] 5. Competitive Positioning - Hengrui is positioned to compete effectively in the Lp(a) and cardiovascular markets, with a small molecule program that is less than a year behind competitors like Lilly [23][30] - The company is exploring both primary and secondary prevention strategies in cardiovascular health, which could provide earlier market entry opportunities [23][30] 6. Regulatory Advantages - Hengrui plans to leverage China's regulatory advantages to accelerate clinical trial timelines, ensuring consistency across multi-regional trials [24][30] - The company is focused on meeting global regulatory standards while addressing ethnic diversity requirements [24][30] 7. Long-Term Growth and Margins - Hengrui expects profit margins to improve as its pipeline shifts towards innovative drugs, which typically carry higher margins [30][10] - The company is diversifying across therapeutic areas to address significant unmet medical needs both domestically and globally [26][30] 8. Risks and Challenges - Potential risks include GPO/NRDL negotiation challenges, R&D risks, and intensified market competition [33][10] - The company is also navigating the complexities of commercial insurance in China, which currently has limited penetration but is expected to grow over the next decade [27][30] Conclusion Hengrui Pharmaceuticals is strategically positioned for growth through innovative drug development, global partnerships, and leveraging regulatory advantages in China. The company's focus on high-value business development and a diversified pipeline across key therapeutic areas supports its long-term profitability and competitive resilience in the biopharma landscape.

Core Insights - The top three companies with the highest short positions as of October 3 are COSCO Shipping Holdings (01919), Ganfeng Lithium (01772), and ZTE Corporation (00763), with short ratios of 15.66%, 15.25%, and 15.16% respectively [1][2] - Ganfeng Lithium (01772) saw the largest absolute increase in short positions, rising by 1.20%, followed by Minmetals Resources (01208) with an increase of 0.96%, and Yuexiu Transport Infrastructure (01052) with an increase of 0.76% [1][2] - The companies with the largest decreases in short positions include GCL-Poly Energy (03800), which decreased by 3.16%, followed by Dongfang Electric (01072) with a decrease of 2.03%, and Jinxin Fertility (01951) with a decrease of 0.76% [1][3] Summary of Short Positions - **Top 10 Companies by Short Ratio** - COSCO Shipping Holdings (01919): 15.66% (from 437 million shares to 451 million shares) - Ganfeng Lithium (01772): 15.25% (from 62.30 million shares to 67.64 million shares) - ZTE Corporation (00763): 15.16% (from 113 million shares to 115 million shares) - CATL (03750): 13.83% (from 21.12 million shares to 21.57 million shares) - Vanke (02202): 12.63% (from 268 million shares to 279 million shares) - Ping An Insurance (02318): 12.59% (from 959 million shares to 938 million shares) - Zijin Mining (02899): 12.58% (from 750 million shares to 754 million shares) - MicroPort Medical (00853): 11.10% (from 213 million shares to 212 million shares) - Hansoh Pharmaceutical (01276): 11.01% (from 28.01 million shares to 28.43 million shares) - Fuyao Glass (06865): 10.85% (from 49.22 million shares to 47.94 million shares) [2] - **Top 10 Companies with Increased Short Positions** - Ganfeng Lithium (01772): Increased by 1.20% (from 14.05% to 15.25%) - Minmetals Resources (01208): Increased by 0.96% (from 1.96% to 2.93%) - Yuexiu Transport Infrastructure (01052): Increased by 0.76% (from 1.08% to 1.84%) - Jinli Permanent Magnet (06680): Increased by 0.66% (from 7.76% to 8.42%) - China Civil Aviation Information Network (00696): Increased by 0.58% (from 6.63% to 7.21%) [2] - **Top 10 Companies with Decreased Short Positions** - GCL-Poly Energy (03800): Decreased by 3.16% (from 11.76% to 8.59%) - Dongfang Electric (01072): Decreased by 2.03% (from 6.78% to 4.75%) - Jinxin Fertility (01951): Decreased by 0.76% (from 10.61% to 9.85%) - Yangtze Optical Fibre and Cable (06869): Decreased by 0.75% (from 7.03% to 6.28%) - Shanghai Electric (02727): Decreased by 0.72% (from 2.25% to 1.52%) [3][4]

Core Viewpoint - Heng Rui Medicine (01276) announced a share buyback of 907,300 A-shares for a total expenditure of 62.4383 million yuan on October 10, 2025 [1] Group 1 - The company is actively engaging in share repurchase to enhance shareholder value [1] - The total amount allocated for the buyback is approximately 62.44 million yuan [1] - The number of shares repurchased is 907,300 A-shares [1]

Core Viewpoint - Heng Rui Medicine (01276.HK) announced a share buyback plan, indicating confidence in its stock value and future prospects [1] Group 1: Buyback Details - The company plans to repurchase 907,300 A-shares at a total cost of RMB 62.4383 million [1] - The buyback price per share is set between RMB 68.05 and RMB 69.66 [1]

FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) 表格類別： 股票 狀態： 新提交 公司名稱： 江蘇恒瑞醫藥股份有限公司 呈交日期： 2025年10月10日 如上市發行人的已發行股份或庫存股份出現變動而須根據《香港聯合交易所有限公司（「香港聯交所」）證券上市規則》(「《主板上市規則》」)第13.25A條 / 《香港聯合交易所有限公司GEM證券 上市規則》(「《GEM上市規則》」)第17.27A條作出披露，必須填妥第一章節 。 確認 根據《主板上市規則》第13.25C條 / 《GEM上市規則》第17.27C條，我們在此確認，據我們所知所信，第一章節所述的每項股份發行或庫存股份出售或轉讓已獲發行人董事會正式授權批准，並遵 照所有適用上市規則、法律及其他監管規定進行，並在適用的情況下： (註7) (i) 上市發行人已收取其在是次股份發行或庫存股份出售或轉讓應得的全部款項； (viii) 有關債券、借貸股份、票據或公司債券的信託契約/平邊契據經已製備及簽署，有關詳情已送呈公司註冊處處長存檔（如法律如此規定）。 第一章節註釋： | 第一章節 | | | | | ...

Core Insights - The article highlights the top and bottom AH share premium rates as of October 10, with Northeast Electric (00042) leading at a premium rate of 757.14% and Ningde Times (03750) at the bottom with -9.58% [1][2][3] Summary by Category Top AH Share Premium Rates - Northeast Electric (00042) has a premium rate of 757.14% with a deviation value of -57.47% - Zhejiang Shibao (01057) follows with a premium rate of 233.74% and a deviation value of 17.26% - Andeli Juice (02218) ranks third with a premium rate of 229.63% and a deviation value of 0.36% [1][2] Bottom AH Share Premium Rates - Ningde Times (03750) has a premium rate of -9.58% with a deviation value of 3.87% - Heng Rui Pharmaceutical (01276) has a premium rate of -1.10% with a deviation value of 1.03% - China Merchants Bank (03968) ranks third from the bottom with a premium rate of 4.00% and a deviation value of -1.87% [1][3] Top AH Share Deviation Values - Changfei Optical Fiber (06869) leads with a deviation value of 29.31% and a premium rate of 160.79% - Zhejiang Shibao (01057) has a deviation value of 17.26% with a premium rate of 233.74% - SMIC (00981) ranks third with a deviation value of 16.66% and a premium rate of 125.88% [1][4] Bottom AH Share Deviation Values - Northeast Electric (00042) has the lowest deviation value at -57.47% despite its high premium rate - Shanghai Electric (02727) follows with a deviation value of -19.08% and a premium rate of 155.47% - Qin Port Co. (03369) ranks third with a deviation value of -12.84% and a premium rate of 47.55% [1][6]

承董事會命 江蘇恒瑞醫藥股份有限公司 董事長 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容所產生或因依賴 該等內容而引致的任何損失承擔任何責任。 Jiangsu Hengrui Pharmaceuticals Co., Ltd. 江蘇恒瑞醫藥股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：1276） 海外監管公告 本公告乃根據香港聯合交易所有限公司證券上市規則第13.10B條刊發。 根據中華人民共和國的有關法例規定，江蘇恒瑞醫藥股份有限公司（「本公司」）在 上海證券交易所網站( www.sse.com.cn )刊發了以下公告。茲載列如下，僅供參閱。 孫飄揚先生 中國上海 2025年10月9日 於本公告日期，董事會成員包括(i)執行董事孫飄揚先生、戴洪斌先生、馮佶女 士、張連山先生、江寧軍先生及孫杰平先生；(ii)非執行董事郭叢照女士；及(iii) 獨立非執行董事董家鴻先生、曾慶生先生、孫金雲先生及周紀恩先生。 证券代码：600276 证券简称：恒瑞医药 公告编号：临 2025-16 ...

智通财经APP讯，恒瑞医药(01276)发布公告，于2025年10月9日斥资762.67万元回购11万股A股股份。 ...

格隆汇10月9日丨恒瑞医药(01276.HK)发布公告，2025年10月9日耗资人民币762.67万元回购11万股A 股，回购价格每股69.2-69.81元。 ...