国盛证券指出，过节期间，辉瑞和特朗普达成协议，部分解除了海外MNC的政策担忧，海外MNC迎来 修复，同时也带动港股医药情绪有所修复，对CXO带来正面影响，在这个影响下，中小市值创新药-B 公司尤其是未进通的表现弹性较大。这段时间CXO确实表现相对强势，有业绩期比较优势，也有降息 预期影响，也有行业趋势拐点向上预期影响，几点共振，中长期值得期待。创新药近期因为缺少催化， 借势消化筹码，也有企稳迹象，看好十一后，尤其是Q4创新药表现。 消息面上，中泰证券认为，9月板块延续震荡调整，主要由于3月以来医药板块超额明显，短期内板块催 化相对较少，板块缺少持续上行强动力；此外创新药板块年初以来涨幅较大，资金有兑现收益的需求。 该行认为阶段的震荡调整是相对良性的，且基本面来看创新逻辑并未发生变化。受益海外降息预期、订 单回暖等催化，创新产业链CRO&CDMO、上游等带动医疗服务板块取得较好表现。长周期来看当前医 药板块仍处于估值底部，具备较强的安全边际和上升潜力。 来源：智通财经网 医药股今日普遍重挫，截至发稿，三叶草生物-B(02197)跌14.43%，报2.49港元；荣昌生物(09995)跌 11.54%，报105.4 ...

（文章来源：每日经济新闻） 每经AI快讯，医药股今日普遍重挫，截至发稿，三叶草生物-B(02197.HK)跌14.43%，报2.49港元；荣昌 生物(09995.HK)跌11.54%，报105.4港元；诺诚健华(09969.HK)跌11.48%，报16.65港元；歌礼制药- B(01672.HK)跌9.16%，报10.51港元；泰格医药(03347.HK)跌7.08%，报43.86港元。 ...

医药股今日普遍重挫，截至发稿，三叶草生物-B(02197)跌14.43%，报2.49港元；荣昌生物(09995)跌 11.54%，报105.4港元；诺诚健华(09969)跌11.48%，报16.65港元；歌礼制药-B(01672)跌9.16%，报10.51 港元；泰格医药（300347）(03347)跌7.08%，报43.86港元。 国盛证券指出，过节期间，辉瑞和特朗普达成协议，部分解除了海外MNC的政策担忧，海外MNC迎来 修复，同时也带动港股医药情绪有所修复，对CXO带来正面影响，在这个影响下，中小市值创新药-B 公司尤其是未进通的表现弹性较大。这段时间CXO确实表现相对强势，有业绩期比较优势，也有降息 预期影响，也有行业趋势拐点向上预期影响，几点共振，中长期值得期待。创新药近期因为缺少催化， 借势消化筹码，也有企稳迹象，看好十一后，尤其是Q4创新药表现。 消息面上，中泰证券（600918）认为，9月板块延续震荡调整，主要由于3月以来医药板块超额明显，短 期内板块催化相对较少，板块缺少持续上行强动力；此外创新药板块年初以来涨幅较大，资金有兑现收 益的需求。该行认为阶段的震荡调整是相对良性的，且基本面来看创 ...

Group 1 - Pharmaceutical stocks experienced a significant decline, with notable drops in companies such as Clover Biopharma-B (down 14.43% to HKD 2.49), Rongchang Biopharma (down 11.54% to HKD 105.4), and Innovent Biologics (down 11.48% to HKD 16.65) [1] - According to Zhongtai Securities, the pharmaceutical sector has been in a phase of adjustment since September, primarily due to the substantial outperformance since March, leading to a lack of strong upward momentum in the short term [1] - The firm views the current phase of adjustment as relatively healthy, with the fundamental innovation logic remaining unchanged, and anticipates that the pharmaceutical sector is still at a valuation bottom with strong safety margins and upside potential in the long term [1] Group 2 - Guosheng Securities noted that during the holiday period, Pfizer and Trump reached an agreement that alleviated policy concerns for overseas MNCs, positively impacting the sentiment in the Hong Kong pharmaceutical market and benefiting CXO companies [2] - The CXO sector has shown relative strength due to performance advantages during earnings periods, expectations of interest rate cuts, and an anticipated upward trend in the industry, making it a sector to watch for medium to long-term potential [2] - Recent lack of catalysts for innovative drugs has led to a phase of digestion of positions, but there are signs of stabilization, with optimism for performance improvement post-October, particularly in Q4 [2]

FF301 股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年9月30日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 三葉草生物製藥有限公司 (「本公司」) (於開曼群島註冊成立的有限公司) 呈交日期: 2025年10月3日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02197 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 2,000,000,000 | USD | | 0.0001 USD | | 200,000 | | 增加 / 減少 (-) | | | | | | USD | | | | 本月底結存 | | | 2,000,000,000 | USD | | 0.0001 USD | | 200,000 ...

智通财经APP获悉，医药股再度强势，截至发稿，三叶草生物-B(02197)涨20.26%，报2.73港元；歌礼制 药-B(01672)涨15.05%，报11.47港元；康宁杰瑞制药-B(09966)涨11.02%，报15.21港元；药明合联 (02268)涨6.96%，报83.75港元；君实生物(01877)涨6.7%，报32.5港元。 消息面上，9月26日，美国总统特朗普宣布，从2025年10月1日起，将对任何品牌或专利的医药产品征收 100%的关税，除非公司正在美国建立他们的制药工厂。西南证券判断，预计该行政命令落地存在不确 定性。对中国创新药企而言，预计有直接创新药出口无美国建厂且对美国市场依赖度高的企业短期承 压；其余通过BD出海企业受影响较小，以License-out为例，其本质是知识产权交易，不涉及实体药品 出口，因此该政策对中国药企影响有限。中邮证券也表示，关税实际影响小，下跌为创新药加仓良机。 兴业证券指出，从创新药板块催化剂角度，进入10月将迎来ESMO（（10月17日-10月21日），此外12 月还有ASH（美国血液学学会）、圣安东尼奥乳腺癌大会等行业会议。另一方面，今年的对外授权交易 持 ...

每经AI快讯，10月2日，港股三叶草生物-B(02197.HK)涨超21%，截至发稿，涨21.15%，报2.75港元， 成交额4221.86万港元。 ...

消息面上，今年6月，三叶草生物宣布，用于评估基于公司独有的 Trimer-Tag （蛋白质三聚体化）疫苗 研发平台开发的呼吸道联合疫苗候选产品SCB-1022（RSV+hMPV）与SCB-1033（RSV+hMPV+PIV3） （Pre-F 三聚体亚单位疫苗抗原）已完成首批受试者入组，正式启动 I 期临床试验。三叶草生物首席执 行官兼执行董事梁果此前指出，当前已批准上市的重组蛋白RSV疫苗虽然安全有效，但全球仍存在关键 未满足的临床需求——包括无法预防和减轻因人偏肺病毒（hMPV）和副流感病毒3型（PIV3）等由类 似 RSV 结构病毒造成的呼吸道疾病负担。 智通财经APP获悉，三叶草生物-B(02197)涨超21%，截至发稿，涨21.15%，报2.75港元，成交额4221.86 万港元。 ...

三叶草生物-B(02197)涨超21%，截至发稿，涨21.15%，报2.75港元，成交额4221.86万港元。 消息面上，今年6月，三叶草生物宣布，用于评估基于公司独有的Trimer-Tag(蛋白质三聚体化)疫苗研发 平台开发的呼吸道联合疫苗候选产品SCB-1022(RSV+hMPV)与SCB-1033(RSV+hMPV+PIV3)(Pre-F三聚 体亚单位疫苗抗原)已完成首批受试者入组，正式启动I期临床试验。三叶草生物首席执行官兼执行董事 梁果此前指出，当前已批准上市的重组蛋白RSV疫苗虽然安全有效，但全球仍存在关键未满足的临床需 求——包括无法预防和减轻因人偏肺病毒(hMPV)和副流感病毒3型(PIV3)等由类似RSV结构病毒造成的 呼吸道疾病负担。 ...

Core Viewpoint - The Hong Kong pharmaceutical sector has experienced a significant surge in stock prices, with many companies seeing increases of over 600%, yet most of these companies remain unprofitable, raising questions about whether this is a genuine market correction or speculative trading [1][3][11]. Group 1: Market Performance - In the period from July 1 to September 18, 2018, 201 out of 264 pharmaceutical companies listed in Hong Kong saw their stock prices rise, with 69 companies increasing by over 50% and 21 companies doubling their stock prices [3]. - Notable stock performances include New Wave Pharma (06108.HK) with a 928.71% increase, Beihai Kangcheng-B (01228.HK) at 802.70%, and Clover Biopharma-B (02197.HK) at 629.77% [4]. Group 2: Individual Company Analysis - Yaojie Ankang-B (02617.HK) saw its stock price soar from an IPO price of 13.15 HKD to a peak of 679.5 HKD, before experiencing a dramatic drop to 165.1 HKD, resulting in a market capitalization decline from nearly 270 billion HKD to 65.5 billion HKD [1][5]. - Beihai Kangcheng reported a revenue of 0.92 million HKD for 2024, a decrease of 17.27%, with a net loss of 478 million HKD [7]. - Clover Biopharma reported a revenue of 41.49 million HKD for 2024, a decrease of 2.13%, and a net loss of 976 million HKD, which is an increase of 550% year-on-year [9]. Group 3: Investment Strategies - Investors have adopted various strategies, with some achieving high returns through direct investments in innovative drugs, while others prefer ETFs for a more stable approach [10]. - One investor reported a 110% return on an ETF investment in innovative drugs, while another faced a 30% loss after investing heavily in Yaojie Ankang [10]. Group 4: Market Dynamics - The surge in the Hong Kong pharmaceutical sector is attributed to its inherent characteristics, such as high speculative value and event-driven dynamics, which attract short-term capital [11][12]. - The market's structure, including a lack of price limits and low liquidity, facilitates significant price volatility, making it easier for small amounts of capital to influence stock prices [25][19]. Group 5: Regulatory Considerations - Experts suggest that the index inclusion rules should be optimized to focus more on a company's fundamentals and liquidity, reducing the likelihood of stocks being manipulated [28]. - The current index inclusion criteria heavily rely on quantitative metrics, often overlooking the underlying business stability and profitability of companies [26].