证券研究报告 行业及产业 医药生物 一年内行业指数与沪深 300 指数对比走势： 资料来源：聚源数据，爱建证券研究所 相关研究 行业研究 / 行业点评 2026 年 03 月 23 日 《医药行业跟踪报告：全球首款侵入式脑机接 口医疗器械在中国获批上市》2026-03-16 《医药行业跟踪报告：生物医药首次被列为国 家"新兴支柱产业"，战略定位进一步提升》 2026-03-10 《医药行业跟踪报告：中国创新 ADC 闪耀 ASCO GU，长效三靶点减肥药二期临床成功》 2026-03-02 《医药行业跟踪报告：信达生物与礼来合作再 度升级，打造全球创新生态体系》2026-02-09 《医药行业跟踪报告：MNC 重金加码中国创新 药，中国 IO2.0 双抗出海迈出关键一步》 2026-02-02 证券分析师 张智聪 S0820525020002 021-32229888-25524 zhangzhicong@ajzq.com ——医药行业跟踪报告 GSK 首创小核酸新药拟纳入优先审评， 有望实现乙肝功能性治愈 强于大市 投资要点： 医药板块行情复盘：本周（3/16~3/22）中东战事持续，市场整体承压，风险偏好 ...

Core Insights - The report emphasizes the investment opportunities in the innovative drug industry chain and undervalued sectors within the pharmaceutical and biotechnology industry [1] - The investment rating is maintained at "Outperform the Market" [2] Group 1: Innovative Drug Development - Continuous progress in clinical development of innovative drugs is noted, with recent excellent clinical data from domestic innovative drugs presented at academic conferences, suggesting a focus on major academic meetings like ASCO in Q2 [4] - The trend of domestic innovative drugs expanding internationally continues, with multiple cooperation agreements indicating the recognition of China's R&D capabilities by multinational pharmaceutical companies [4] Group 2: CXO Industry Investment Opportunities - The CXO sector is identified as the strongest investment theme in the pharmaceutical sector, driven by improved international financing and a robust domestic innovative drug R&D environment [4] - Recommendations include companies such as WuXi AppTec, WuXi Biologics, and Kelun Pharmaceutical, which are expected to benefit from the growing demand in preclinical and clinical stages [4] Group 3: Home Medical Devices and Chain Pharmacies - The home medical device sector is projected to experience strong growth due to aging demographics and increased demand for popular products, with companies like Yuyue Medical and Sanofi Biologics highlighted for their strong positioning [4] - The retail pharmacy sector is expected to consolidate, with leading chain pharmacies like Yifeng Pharmacy and Dazhong Pharmacy likely to gain market share through effective supply chain management and acquisition capabilities [4] Group 4: Surgical Robotics Investment Opportunities - The National Healthcare Security Administration has introduced guidelines for pricing surgical and treatment assistance services, which may enhance the clinical application of intelligent innovative products [4] - Companies like MicroPort and Tianzhihang are noted for their advancements in surgical robotics and international market expansion [4] Group 5: Investment Portfolio - The investment portfolio includes A-shares such as Mindray Medical, United Imaging, and Aier Eye Hospital, as well as H-shares like CanSino Biologics and Hutchison China MediTech [4] Group 6: Industry Performance and Data Tracking - The pharmaceutical manufacturing industry reported a revenue of 24,870 billion yuan in 2025, with a slight decline of 1.2% year-on-year, while total profits increased by 2.7% to 3,490 billion yuan [8] - The retail sales of pharmaceuticals reached 7,294 billion yuan, reflecting a growth of 1.8% year-on-year [8] Group 7: Monthly Performance Review - The pharmaceutical sector experienced a slight decline of 0.18% in February, underperforming against the CSI 300 index [9] - The report indicates that the overall valuation of the pharmaceutical sector is relatively high, with a current PE (TTM) of 37.20, placing it in the 80.66% historical percentile [15]

Investment Rating - The industry investment rating is "stronger than the market" (预计6个月内，行业指数表现强于市场表现5%以上) [32] Core Insights - Jichuan Pharmaceutical has secured exclusive commercialization rights for the drug Bimekizumab (brand name: Zeli Mei) in mainland China, excluding Hong Kong, Macau, and Taiwan, with a total payment not exceeding RMB 190 million (including tax) [3][13] - Bimekizumab is the first approved treatment for eczema in children aged 2 and above, acting as an aromatic hydrocarbon receptor (AhR) modulator to suppress inflammation and repair skin barriers [3][13] - The product is expected to be approved for market launch in November 2024 and currently is not included in the National Basic Medical Insurance Drug List, indicating it is in the early stages of market expansion [3][13] Summary by Sections Industry Viewpoints - The report emphasizes the continuous improvement of global competitiveness among Chinese innovative pharmaceutical companies, suggesting a focus on potential treatment areas such as metabolic diseases, chronic diseases, and central nervous system disorders [4] - It also highlights emerging technology platforms like small nucleic acid drugs and CAR-T therapies, recommending companies such as Baiji Shenzhou and Dongcheng Pharmaceutical for investment [4] Industry News - Jichuan Pharmaceutical's acquisition of Bimekizumab is noted as a significant development in the biopharmaceutical sector, providing a new treatment option for eczema [7][13] - GSK's acquisition of 35Pharma for $950 million to gain access to a new pulmonary arterial hypertension drug is also highlighted, showcasing ongoing consolidation in the industry [14] - GSK's submission of a new hepatitis B drug, Bepirovirsen, for market approval in Japan is mentioned, indicating advancements in chronic hepatitis treatment [16][17] - The approval of a new JAK/ROCK inhibitor by Zhengda Tianqing for treating primary myelofibrosis is noted, reflecting innovation in hematological therapies [18] Market Performance - The pharmaceutical sector saw a 0.50% increase last week, while the Shanghai and Shenzhen 300 Index rose by 1.08%, ranking 21st among 28 industries [8][20] - The Hong Kong pharmaceutical sector experienced a decline of 6.07%, with the Hang Seng Index down by 1.93%, ranking 11th among 11 industries [31]

Investment Rating - The report maintains a "Buy" rating for the pharmaceutical sector, emphasizing a positive outlook for the recovery of the industry [3][4]. Core Viewpoints - The report expresses a strong belief in the recovery of the pharmaceutical sector, reiterating the investment thesis based on the "three stages of clinical value": 1) "0→1" technological breakthroughs in innovative drugs and devices; 2) "1→10" clinical validation of high-quality domestic innovative drugs; 3) "10→100" efficiency in the Chinese pharmaceutical industry [2][19][20]. - The report highlights the acceleration of BD (Business Development) for innovative drugs and the growth of domestic CXO (Contract Research Organization) companies, as well as the rise of high-end medical devices and high-value consumables [2][20]. Summary by Sections Market Review - Last week, the A-share pharmaceutical index rose by 0.50%, underperforming the CSI 300 index by 0.58 percentage points and the ChiNext index by 1.82 percentage points, ranking 25th among 31 sub-industries [1][14]. - The Hong Kong Hang Seng Medical Health Index fell by 6.07%, underperforming the Hang Seng Index by 4.96 percentage points [1][14]. R&D Progress - Recent clinical applications include CMS-D008 injection from Kangzhe Pharmaceutical and KC1036 tablets from Kangchen Pharmaceutical, both newly undertaken; IND applications for HSK46575 tablets from Haishike and other products are also in progress [1][24]. Key Company Recommendations - The report recommends several companies based on their potential in the innovative drug sector and medical devices: - Innovative drugs: Innovent Biologics (H), Yifang Biologics (U), Tianjin Pharmaceutical - CXO companies: WuXi AppTec (A+H), Proprius - High-end medical devices: Mindray Medical, United Imaging Healthcare, Weisi Medical [2][20]. Financial Forecasts and Valuations - The report provides earnings per share (EPS) and price-to-earnings (PE) ratios for key companies, indicating a positive outlook for their financial performance [3]. - For instance, Tianjin Pharmaceutical is projected to have an EPS of 0.77 yuan in 2025 with a PE of 19, while Innovent Biologics is expected to reach an EPS of 0.49 yuan with a significantly higher PE of 154 [3]. Important Updates - The report includes updates on clinical trial approvals and progress for various companies, indicating ongoing innovation and development within the sector [23][24]. - It also notes the stability of prices for key pharmaceutical raw materials and the overall performance of the pharmaceutical manufacturing industry, which saw a year-on-year revenue decline of 1.2% [28][45].

Investment Rating - The report indicates a positive investment outlook for the innovative drug sector, highlighting the arrival of a turning point for companies in this field [4]. Core Insights - The medical device sector is experiencing a recovery in domestic demand, with opportunities for overseas expansion, particularly in innovative devices supported by policies such as brain-computer interfaces and surgical robots [4]. - The approval of Dupilumab for a new indication (AFRS) marks a significant milestone as it becomes the first drug globally for this condition, addressing a high unmet clinical need [36][37]. - The GLP-1 three-target receptor agonist UBT251 has shown promising results in clinical trials, with a weight reduction of up to 19.7% after 24 weeks, indicating strong potential in the obesity treatment market [38][39]. Summary by Sections Innovative Drugs - Dupilumab has been approved for the treatment of allergic fungal sinusitis (AFRS), showing significant improvement in nasal congestion scores compared to placebo [36][37]. - The innovative drug sector is expected to benefit from a series of clinical data releases and successful overseas clinical progress [4]. Biologics - The UBT251 clinical trial results indicate a substantial average weight loss of 19.7% in treated patients, suggesting a strong efficacy profile for obesity management [38][39]. - The report emphasizes the importance of monitoring the development of GLP-1 three-target drugs, which may enhance therapeutic efficacy [38]. CXO and Pharmaceutical Supply Chain - The CXO sector is showing continued upward momentum, with several companies reporting better-than-expected revenue growth and positive guidance for 2026 [43][44]. Medical Devices - The National Medical Products Administration (NMPA) approved 76 innovative medical devices in 2025, a 17% increase year-on-year, focusing on key areas like brain-computer interfaces and high-end imaging equipment [2][4]. - Leading companies in the medical device sector are experiencing accelerated growth, particularly in Q4, as core products gain traction [2]. Traditional Chinese Medicine - The report highlights the release of the National Essential Medicines List Management Measures, suggesting ongoing updates to the essential medicines directory [3]. Medical Services and Consumer Healthcare - The Jin Xin Kang Yang Industrial Group has submitted a listing application, ranking second in the number of integrated medical and elderly care facilities in China [3].

Industry Rating - The report rates the pharmaceutical industry as "Leading" [1] Core Insights - The upcoming ASCO GU conference is expected to showcase significant data from over 70 studies led by Chinese experts, which may catalyze market performance for innovative pharmaceutical companies [4][5] - The report suggests a stable outlook for the sector in 2026, despite potential short-term volatility, emphasizing the importance of fundamental analysis and valuation in stock selection [4] Valuation Summary - The report provides a detailed valuation overview of various companies, with all listed companies rated as "Buy" except for Heng Rui Pharmaceutical and Bristol-Myers Squibb, which are rated as "Neutral" and "Sell" respectively [3] - Notable target prices and current prices include: - AstraZeneca (AZN US): Target Price 93.30, Current Price 203.98 - BeiGene (6160 HK): Target Price 231.00, Current Price 194.40 - Innovent Biologics (1801 HK): Target Price 105.00, Current Price 84.35 [3] Market Performance - During the Spring Festival period (February 10-24, 2026), the Hang Seng Index fell by 2.2%, while the Hang Seng Healthcare Index decreased by 1.5%, ranking 8th among 12 industry indices [4][6] - Sub-industry performance varied, with prescription drugs increasing by 3.4% and internet medicine declining by 5.3% [4][6] Institutional Holdings - As of February 24, 2026, domestic institutional holdings through Hong Kong Stock Connect slightly decreased to 22.2%, while foreign institutional holdings increased to 40.0% [31] - The report highlights a trend of increased foreign investment in innovative pharmaceutical and CXO companies, aligning with domestic investment strategies [35] Investment Recommendations - The report recommends focusing on undervalued innovative drug companies such as Sanofi, Hengrui Medicine, and others with clear long-term growth logic [4] - It also suggests looking into CXO leaders benefiting from high downstream demand and improving financing conditions [4]

Group 1 - The pharmaceutical sector is experiencing significant growth, with BD transaction volumes reaching new highs and domestic innovative drugs gaining international recognition, making it a focal point for investors [1][3] - However, there is a growing fatigue regarding the expectations for innovative drugs going abroad, leading to a shift from a "highlight moment" to a "volatile adjustment" in the market [2][3] - This transition is viewed as a necessary step towards a long-term market trend, with signs of recovery in the pharmaceutical sector as it approaches a new cycle starting in 2026 [3][11] Group 2 - The current investment rationale in the pharmaceutical sector is supported by three main forces: demand, supply, and policy, which are converging to fuel a new round of growth [5][36] - Demand for healthcare is increasing due to an aging population and rising health awareness, transforming medical consumption from optional to essential [6][37] - The supply side shows that China's innovative drugs are becoming globally competitive, with the number of innovative drug pipelines accounting for nearly 30% of the global total and BD overseas licensing transactions reaching $135.7 billion in 2025, a 161% increase year-on-year [7][38] Group 3 - Policy changes are shifting from cost control to empowerment, with new measures introduced to support the entire chain of innovative drug development, access, usage, and payment [10][41] - The Hong Kong stock market is becoming a primary platform for Chinese innovative drug companies due to its flexible listing regulations and foreign investment environment, which has attracted over 70 competitive innovative drug and CXO companies [12][43] - The establishment of the Hong Kong Medical Device Regulatory Center (CMPR) and other supportive mechanisms is expected to enhance the internationalization and business development capabilities of companies listed in Hong Kong [13][44] Group 4 - The Hang Seng Biotechnology Index has outperformed other indices with a 82.75% increase, highlighting its strong market position [16][46] - The index is composed of the top 30 biotechnology companies, focusing on high-growth sectors such as innovative drugs (79% weight) and CXO services (11% weight), ensuring coverage of the core segments of the pharmaceutical industry [17][49] - The index's unique feature includes being the only pharmaceutical-themed index in Hong Kong equipped with index futures, providing risk management tools and enhancing liquidity for investors [23][54] Group 5 - The Hang Seng Biotechnology Index is currently at a historically low valuation, with a PE ratio of 30.01, significantly lower than the NASDAQ Biotechnology Index and the CSI Biotechnology Index, indicating a valuation advantage [26][55] - The index's components are primarily leading innovative drug and CXO companies with solid R&D capabilities, suggesting potential for steady profit release as pipelines mature and orders are fulfilled [28][57] - The current market conditions may present a favorable opportunity for long-term investors to allocate resources into high-quality pharmaceutical assets through the Hang Seng Biotechnology ETF [29][58]

"我买了点医药ETF，从2025年年中慢慢加仓到现在差不多1万元，期待马年创新药还有一波春季行情"，90后小宇（化名）告诉 21世纪经济报道记者。 另一位95后投资者天天（化名）则告诉21世纪经济报道记者，相比传统的制药概念股，"我更看重有消费属性的医疗服务概念， 跟爱尔眼科看眼睛、通策医疗看牙齿是一个道理，毕竟这些刚需还在"。 在投资社区上，不乏网友分享投资医药股的心路历程，"恒瑞医药持有了三年，之前一直处于亏损状态，持有成本58元，漫长的 亏损期真的让人无比难受，但是买入以后没有做任何动作，（2025年）终于等到了盈利的一天"。 随着不少创新药、CXO、高端医疗器械等药企的确定性业绩，助推细分赛道获得市场追捧。 Wind数据显示，截至2026年1月31日，共有283只医药股披露了2025年业绩预告。按预告归母净利润上限看，有160只个股归母净 利润同比增长，占比超五成，释放积极信号，尤其是创新药、CXO、高端医疗器械等细分赛道各有亮点。 在核心产品商业化放量驱动下，不少创新药企从"投入期"步入"收获期"，业绩确定性逐步获得财报验证。 例如，老牌ADC药企荣昌生物预计2025年归母净利润约7.16亿元，而上 ...

近年来，生物科技产业全面步入高速成长期，已成为引领全球科技革命与产业变革的关键赛道，持续吸 引海内外资金加速布局。马年伊始，恒生生物科技ETF华泰柏瑞（认购代码：513933，交易代码： 513930）于2026年2月24日起正式发售，为投资者提供一键布局港股生物科技核心资产的便捷投资工 具。 聚焦产业创新龙头，重点覆盖创新药+CXO方向 从成分股业务构成来看，指数高度聚焦创新药与CXO两大核心方向，合计权重接近90%，创新属性突 出。与此同时，指数还覆盖了AI+医疗等前沿领域优质标的，在精准捕捉医药赛道创新核心环节的同 时，映射中国生物科技产业的整体发展趋势。 凭借较高的创新药+CXO含量及鲜明的科技创新属性，恒生生物科技指数在2025年以来港股医药板块行 情中表现突出。截至2026年2月6日，该指数累计涨幅达76.52%，不仅跑赢同期恒生指数（32.40%）， 也显著超越恒生医疗保健（67.97%）、港股通医疗（34.21%）及恒生港股通创新药指数（70.43%）等 其他港股医药类指数，充分彰显其投资价值与成长弹性。 值得关注的是，截至2026年2月6日，恒生生物科技指数市盈率（PE-TTM）为29.60 ...

Investment Rating - The industry maintains a "Neutral" rating, with specific company ratings of "Buy" for Heng Rui Pharmaceutical (600276) and "Increase" for WuXi Biologics (603259) [46] Core Insights - The recent national drug procurement has been stable, with active participation from companies and continued benefits for patients [8][9] - The issuance of the "National Basic Drug Directory Management Measures" aims to enhance the management of essential medicines [10][11] - Heng Rui Pharmaceutical reported positive top-line results for its GLP-1/GIP dual receptor agonist, indicating significant weight loss in clinical trials [12] - The approval of Mu Feng Da® for the treatment of adult type 2 diabetes marks a significant development in the market [12] Industry News - The national drug procurement involved 316 commonly used drugs across 26 therapeutic areas, with a high participation rate from over 5,100 medical institutions and 1,091 companies [8][9] - The procurement process has been standardized, allowing companies to bid online once for nationwide sales, significantly reducing costs [9] - The management measures for the national basic drug directory have been revised to include legal policy bases and optimize the directory structure [10][11] Company Announcements - Innovent Biologics has entered a global strategic partnership with Eli Lilly to advance new drug development in oncology and immunology [26] - Kelun Pharmaceutical's TROP2 ADC has received approval for a fourth indication from the NMPA [27] - Heng Rui Pharmaceutical's drug has been included in the list of breakthrough therapy products, and its application for marketing approval has been accepted for priority review [28] - WuXi Biologics has forecasted a positive earnings outlook, expecting a revenue increase of approximately 16.7% [30] Market Review - The Shanghai Composite Index rose by 1.43%, while the Shenzhen Component Index increased by 2.37%, with the SW Pharmaceutical and Biotech Index up by 0.23% [36] - The industry’s price-to-earnings ratio (TTM) stands at 51.17, with a valuation premium of 259% compared to the CSI 300 [40] Weekly Strategy - The report suggests focusing on investment opportunities in innovative drugs, CXO, and upstream life sciences, while also monitoring performance recovery indicators [46]