Group 1 - The overall shareholding ratio of southbound funds in Hong Kong Stock Connect stocks is 17.33%, with 206 stocks having a shareholding ratio exceeding 20% [1] - As of June 6, southbound funds held a total of 4,353.69 million shares, accounting for 13.21% of the total market value of the stocks [1] - The highest shareholding ratio by southbound funds is in China Telecom, with 74.53% of its issued shares held, followed by Tigermed and Kaisa New Energy at 69.89% and 67.27% respectively [1] Group 2 - Southbound funds with a shareholding ratio exceeding 20% are mainly concentrated in the healthcare, industrial, and financial sectors, with 40, 31, and 29 stocks respectively [2] - The top stocks by shareholding ratio include China Telecom (74.53%), Tigermed (69.89%), and Kaisa New Energy (67.27%), among others [2][3] - A significant portion of the stocks with high southbound fund ownership are AH concept stocks, with 119 out of 206 stocks (57.77%) having a shareholding ratio over 20% [1]

证券代码：300347 证券简称：泰格医药 公告编码（2025）029 号 杭州泰格医药科技股份有限公司 公司及董事会全体成员保证公告内容的真实、准确和完整，对公告的虚假记载、误导性陈述或 者重大遗漏负连带责任。 特别提示： ）于2025年5月30日召开的 ，现将公司A股 权益分派事宜公告如下，H股股东的权益分派实施情况不适用本公告，H股股东的权益分 派安排请参见公司于香港联合交易所有限公司及公司网站发布的相关公告。 有参与利润分配的权利。因此，公司享有利润分配权的股份总额为总股本扣除本公司回 购专用证券账户持有的股份数量。 股份5,883,780股，公司未进行H股股份回购。 】 按照分配比例不变的原则，调整后的2024 年度A股权益分派方案如下：以本公告日A股总股本737,901,250股扣减公司回购专户持有 股份5,883,780股后可参与分配的A股总股数732,017,470股为基数，向全体股东每10股派 发现金股利3.000000元（含税） ，共计派发现金红利219,605,241.00元（含税） 。剩余未分 配利润，结转以后年度分配；公司不以资本公积金向全体股东转增股本。 现金分红总额÷总股本（含公 ...

证券代码：300347 证券简称：泰格医药 公告编码（2025）029 号 杭州泰格医药科技股份有限公司 2024 年度权益分派实施公告 公司及董事会全体成员保证公告内容的真实、准确和完整，对公告的虚假记载、误导性陈述或 者重大遗漏负连带责任。 特别提示： 2、根据《公司法》的规定，上市公司通过回购专用证券账户持有的公司股份不享 有参与利润分配的权利。因此，公司享有利润分配权的股份总额为总股本扣除本公司回 购专用证券账户持有的股份数量。【注：截至本公告日，公司回购专用证券账户持有A股 股份5,883,780股，公司未进行H股股份回购。】 按照分配比例不变的原则，调整后的2024 年度A股权益分派方案如下：以本公告日A股总股本737,901,250股扣减公司回购专户持有 股份5,883,780股后可参与分配的A股总股数732,017,470股为基数，向全体股东每10股派 发现金股利3.000000元（含税），共计派发现金红利219,605,241.00元（含税）。剩余未分 配利润，结转以后年度分配；公司不以资本公积金向全体股东转增股本。 3、按照公司A股总股本（含公司回购专户持有的股份）折算的每股现金分红=实际 ...

Core Insights - The CXO industry appears to have emerged from a downturn in 2025, with notable profit growth among key players such as WuXi AppTec (89.06%), Hangzhou Tigermed Consulting (32.54%), and Kelun Pharmaceutical (15.83%) [2] - However, Tigermed stands out as the only major player in the CXO sector experiencing a decline, with a 29.61% year-on-year drop in Q1 2025 following a 79.99% decline in 2024 [2][3] Financial Performance - In Q1 2025, Tigermed reported revenue of 1.564 billion yuan, a decrease of 5.79% year-on-year, and a net profit of 165 million yuan, down 29.61% [3] - The gross margin fell from 37.83% in Q1 2024 to 30.03% in Q1 2025, indicating significant challenges in profitability [3] - For the full year 2024, Tigermed's revenue was 6.603 billion yuan, a decline of 10.58%, with net profit plummeting to 405 million yuan, a drop of 79.99% [4][7] Profitability Metrics - Tigermed's profitability has sharply declined, with gross margin decreasing from 47.43% in 2020 to 33.95% in 2024, and further to 30.03% in Q1 2025 [5] - The net profit margin also fell from 63.56% in 2020 to 6.78% in 2024, highlighting a severe reduction in profitability [5] Market Dynamics - The decline in Tigermed's performance is attributed to increased competition and a reduction in financing for innovative drug companies, which impacts order volumes [8][9] - In 2024, the domestic innovative drug financing dropped to approximately 4.2 billion USD, a nearly 20% decrease, affecting cash flow for many companies [9] Strategic Positioning - Tigermed operates as both a CRO service provider and an investment entity, which has created challenges during industry downturns [10] - As of the end of 2024, Tigermed held non-current financial assets worth 10.1 billion yuan, including equity investments in several medical companies [10] - The company reported a significant loss of 502 million yuan in fair value changes in 2024, which heavily impacted its net profit [10] Contractual Developments - Despite the challenges, Tigermed secured new contracts worth 10.12 billion yuan in 2024, with a net increase of 8.42 billion yuan after cancellations, indicating some resilience [10] - In Q1 2025, the net new contract amount exceeded 2 billion yuan, reflecting a 20% year-on-year growth, primarily driven by demand from multinational pharmaceutical companies [11] Expansion Efforts - Tigermed has also completed the acquisition of Japanese CRO Medical Edge to accelerate its overseas expansion [12] - The effectiveness of these measures in mitigating the impact of investment volatility remains uncertain [12]

Group 1 - The core viewpoint of the articles highlights that Tigermed's stock closed at 51.61 yuan, down 2.35%, with a rolling PE ratio of 132.44 times, and a total market capitalization of 44.438 billion yuan [1] - The average PE ratio for the medical services industry is 40.82 times, with a median of 45.93 times, placing Tigermed at the 42nd position in the industry ranking [1] - As of the first quarter of 2025, 80 institutions hold shares in Tigermed, including 78 funds, 1 social security fund, and 1 other entity, with a total shareholding of 170.6648 million shares valued at 8.671 billion yuan [1] Group 2 - Tigermed's main business is providing comprehensive clinical trial services as a Contract Research Organization (CRO) for new drug development, offering solutions for global pharmaceutical and medical device innovation companies [1] - The latest financial results for the first quarter of 2025 show that the company achieved operating revenue of 1.564 billion yuan, a year-on-year decrease of 5.79%, and a net profit of 165 million yuan, down 29.61% year-on-year, with a gross profit margin of 30.03% [1] - The PE ratios for Tigermed compared to industry averages indicate a significant premium, with the industry average PE at 40.82 times and Tigermed's PE at 132.44 times, suggesting potential overvaluation [2]

Group 1 - The pharmaceutical sector has recently experienced a significant pullback, with the innovative drug concept seeing a net outflow of nearly 2.5 billion yuan in A-shares [1] - The Tianhong Innovative Drug ETF (517380) reached a new high for the year before experiencing a substantial decline, dropping 2.75% with a trading volume of 22 million yuan, and most constituent stocks fell nearly 5% [1] - The Tianhong Innovative Drug ETF is the only product tracking the Hang Seng-Hu-Shen-Hong Kong Innovative Drug Selected 50 Index, which includes leading innovative drug companies from the three markets [1] Group 2 - Dongwu Securities predicts that 2025 will mark the explosive growth of China's innovative drug industry, driven by three core factors: significant BD transactions, profitability turning points for leading companies, and an improving policy environment [2] - Guosheng Securities acknowledges short-term trading pullback risks but emphasizes the solid underlying logic and clear trends in the innovative drug sector, maintaining a positive outlook for the innovative drug bull market [2] - The market size of China's innovative drugs is expected to exceed 2 trillion yuan by 2030, with a compound annual growth rate of 24.1% [2]

Core Viewpoint - The A-share medical service sector experienced a short-term decline, with significant drops in several companies' stock prices, indicating potential market volatility in this industry [1] Company Summary - Jinkai Biotechnology saw a decline of over 8% in its stock price [1] - Other companies that followed the downward trend include Sunshine Nuohuo, Tigermed, Hongbo Pharmaceutical, Berry Genomics, and Chengdu Xian Dao [1]

Core Viewpoint - The article highlights a silent revolution in the biotechnology sector in China, where domestic pharmaceutical companies are emerging as global leaders in drug discovery, particularly in the innovative drug segment, contrasting with the rapid advancements in AI technology [1]. Group 1: Market Performance and Trends - The Hong Kong innovative drug sector has seen significant growth, with ETFs like Huatai-PB and others rising by approximately 42% year-to-date as of May 30 [1]. - Chinese innovative drug companies have made notable strides in international markets, exemplified by the $60 billion exclusive development agreement between 3SBio and Pfizer, setting a record for domestic drug licensing [1]. - The total transaction amount for potential business collaborations by companies like CSPC Pharmaceutical is nearing $50 billion, indicating a robust trend in high-value overseas licensing deals [1]. Group 2: Growth Metrics - The number of innovative drugs approved in China has surged from 3 in 2015 to 39 in 2024, marking a 12-fold increase and elevating China from third to second place globally [6]. - The number of innovative drugs undergoing clinical trials in China has increased from 124 in 2015 to 704 in 2024, a 4.7-fold rise, positioning China as the leader in this category [6]. - The procurement amount for innovative drugs in hospitals with over 100 beds has grown from 137.2 billion yuan in 2015 to 257.6 billion yuan in 2024, an 88% increase, with its share of total procurement rising from 20.9% to 29.2% [7]. Group 3: Factors Driving Growth - The return of overseas-educated talent has significantly contributed to the innovation landscape in China's biotechnology sector, as many skilled researchers transitioned from corporate labs to entrepreneurial ventures [11]. - The establishment of a robust diagnostic and reagent business in China during the early 2000s laid the groundwork for advancements in biotechnology [13]. - The increasing domestic market demand, driven by a large and aging population, has created substantial opportunities for innovative drug development, particularly for treatments related to chronic diseases and cancer [12]. Group 4: Global Opportunities and Challenges - The global pharmaceutical market is facing a wave of patent expirations, prompting companies to seek external collaborations, where China's strong R&D capabilities can meet international demands [14]. - The licensing model is seen as a necessary step for Chinese biotech firms to gain experience and eventually achieve global distribution and trial capabilities [10]. - Despite the current reliance on licensing, there is potential for Chinese companies to evolve into global leaders in biotechnology as their ecosystems mature [18]. Group 5: Innovation and Competitive Landscape - China's biotechnology sector is recognized for its rapid iteration and improvement of existing drugs, which is a form of innovation that benefits society significantly [18]. - The development of the bispecific antibody Ivosidenib, which reportedly outperforms Keytruda, exemplifies China's growing technical prowess in biotechnology [18]. - The perception of innovation in China is shifting, as the ability to produce better and safer versions of existing drugs is increasingly valued [33].

Group 1 - The market experienced a rebound on June 4, with the ChiNext Index leading the gains. The total trading volume in the Shanghai and Shenzhen markets reached 1.15 trillion yuan, an increase of 11.6 billion yuan compared to the previous trading day [1] - The innovative drug concept remained active, with the Tianhong Innovative Drug ETF (517380) closing up 2.34%, reaching a peak price of 0.660 yuan, the highest since November 2023, and achieving a trading volume of nearly 20 million yuan, a two-year high [1] - The Tianhong Innovative Drug ETF (517380) has seen a year-to-date increase of 25.96% as of June 4, ranking first among all industry ETFs in the market [1] Group 2 - Changjiang Securities indicated that the valuation level of domestic innovative drugs is low, and some products have the potential to be the best in their class globally, supporting the outlook for innovative drugs to expand internationally and achieve premium valuations [2] - Guojin Securities emphasized that innovative drugs and certain semi-innovative drugs are key investment focuses, with upcoming policy changes and data releases expected to catalyze stock price movements [2] - Huafu Securities reported that the total transaction amount for innovative drug BD from 2020 to 2024 increased from 9.2 billion USD to 52.3 billion USD, with the upfront payment amount rising from 600 million USD to 4.1 billion USD [2]

Group 1 - The core viewpoint of the articles highlights the active performance of innovative drug ETFs, particularly Tianhong (517380), which has seen significant gains and is leading the market in terms of growth [1][2] - As of June 3, 2025, the Tianhong innovative drug ETF has accumulated a year-to-date increase of 23.08%, ranking first among all industry ETFs [1] - The Tianhong ETF tracks the Hang Seng Shanghai-Shenzhen-Hong Kong Innovative Drug Selected 50 Index, which includes leading innovative drug companies from the three regions, indicating a high concentration of innovation [1] Group 2 - In the first five months of 2025, the National Medical Products Administration approved over 20 first-class innovative drugs, setting a record for the same period in the past five years [2] - The recent acceleration in the approval of innovative drugs in China reflects a shift from "follow-up innovation" to "global leadership" in the pharmaceutical sector [2] - The innovative drug sector is expected to experience a valuation reshaping, with significant catalysts such as overseas business development and the ASCO conference driving interest in the sector [2]