Core Viewpoint - Zhaoyan New Drug's stock price has shown significant volatility, with a year-to-date increase of 100.36% but a recent decline in the last five trading days by 5.81% [1] Group 1: Stock Performance - As of October 14, Zhaoyan New Drug's stock price was 33.26 CNY per share, with a market capitalization of 24.928 billion CNY [1] - The stock has experienced a 27.38% increase over the past 60 days, while it has decreased by 4.01% over the last 20 days [1] - The company has appeared on the "Dragon and Tiger List" three times this year, with the most recent occurrence on September 15 [1] Group 2: Financial Performance - For the first half of 2025, Zhaoyan New Drug reported a revenue of 669 million CNY, a year-on-year decrease of 21.28%, while the net profit attributable to shareholders was 60.932 million CNY, reflecting a year-on-year increase of 135.90% [2] - Cumulative cash dividends since the company's A-share listing amount to 703 million CNY, with 356 million CNY distributed over the past three years [3] Group 3: Shareholder Structure - As of June 30, 2025, the number of shareholders increased to 61,200, a rise of 25.59% compared to the previous period [2] - The top circulating shareholder, Huabao Zhongzheng Medical ETF, holds 14.6531 million shares, an increase of 2.2669 million shares from the previous period [3] - Hong Kong Central Clearing Limited, ranked as the eighth largest circulating shareholder, reduced its holdings by 9.4387 million shares to 8.2811 million shares [3]

Core Insights - The article highlights the changes in the Hong Kong Stock Connect holdings, indicating which companies saw the largest increases and decreases in ownership percentages over recent trading days [1][2]. Summary by Category Recent Changes in Holdings - Xinyi Energy (03868) saw an increase of 0.07% in its Hong Kong Stock Connect holding percentage, bringing the total to 12.98% [2]. - The Yingfu Fund (02800) increased by 0.05%, now at 2.10% [2]. - Haier Smart Home (06690) increased by 0.02%, with a current holding of 16.62% [2]. - Horizon Robotics-W (09660) experienced the largest decrease, with a drop of 0.82%, now at 14.69% [2]. - Southern Hang Seng Technology (03033) decreased by 0.63%, now at 59.30% [2]. - WuXi AppTec (02359) saw a decrease of 0.56%, with a current holding of 15.03% [2]. Five-Day Changes - The largest increase over the last five trading days was for Da Zhong Public Utilities (01635), which rose by 3.98% to 67.37% [3]. - Zhong Chuang Innovation (03931) increased by 1.40%, now at 17.08% [3]. - Zhaoyan New Drug (06127) rose by 1.08%, with a holding of 50.59% [3]. - The largest decrease was for Southern Hang Seng Technology (03033), which fell by 2.01% to 59.30% [3]. - Haotian International Construction (01341) decreased by 1.58%, now at 58.50% [3]. Twenty-Day Changes - Da Zhong Public Utilities (01635) had the most significant increase over the past twenty days, rising by 34.46% to 67.37% [4]. - Canggang Railway (02169) increased by 31.45%, now at 43.11% [4]. - Shanga Holdings (00412) rose by 13.53%, with a current holding of 15.00% [4].

Core Insights - The article highlights the top and bottom AH premium rates for various stocks as of October 9, with Northeast Electric (00042) leading at a premium of 743.75% [1][2]. AH Premium Rate Rankings - The top three stocks with the highest AH premium rates are: - Northeast Electric (00042): 743.75% - Andeli Juice (02218): 235.25% - Zhejiang Shibao (01057): 227.36% [1][2] - The bottom three stocks with the lowest AH premium rates are: - Contemporary Amperex Technology (03750): -16.12% - Heng Rui Medicine (01276): -2.39% - China Merchants Bank (03968): 3.49% [1][2] Deviation Values - The stocks with the highest deviation values are: - Changfei Optical Fiber (06869): 28.93% - Zhejiang Shibao (01057): 12.23% - Red Star Macalline (01528): 11.20% [1][2] - The stocks with the lowest deviation values are: - Northeast Electric (00042): -72.24% - Shanghai Electric (02727): -54.73% - Dazhong Public Utilities (01635): -29.80% [1][2]

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年9月30日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 北京昭衍新藥研究中心股份有限公司 呈交日期: 2025年10月8日 第 1 頁 共 11 頁 v 1.1.1 FF301 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | | 於香港聯交所上市 (註1) | 是 | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 06127 | 說明 | | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | | 118,995,206 | RMB | | 1 | RMB | | 118,995,206 | | 增加 / 減少 (-) | | | 0 | | | | RMB | | 0 | | 本月底結存 | | | 118,995,206 | RMB | | 1 | RMB ...

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年9月30日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 北京昭衍新藥研究中心股份有限公司 呈交日期: 2025年10月8日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | | 於香港聯交所上市 (註1) | 是 | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 06127 | 說明 | | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | | 118,995,206 | RMB | | 1 | RMB | | 118,995,206 | | 增加 / 減少 (-) | | | 0 | | | | RMB | | 0 | | 本月底結存 | | | 118,995,206 | RMB | | 1 | RMB | | 118,995,206 | | 2. 股份分類 ...

目錄 | 釋義 | 2 | | --- | --- | | 技術詞彙 | 5 | | 公司資料 | 6 | | 財務概要 | 8 | | 主席報告 | 9 | | 管理層討論及分析 | 10 | | 企業管治及其他資料 | 29 | | 未經審核綜合損益及其他全面收益表 | 40 | | 未經審核綜合財務狀況表 | 42 | | 未經審核綜合權益變動表 | 44 | | 未經審核綜合現金流量表 | 46 | | 未經審核中期財務報告附註 | 47 | 釋義 於本報告內，除文義另有所指外，下列詞彙具有以下涵義。該等詞彙及其定義未必與任何業內標準定義相符，亦未必 可直接與其他在本公司相同行業內經營的公司所採用的同類詞彙比較。 | 「2022年H股激勵計劃」 | 指 | 本公司於2022年6月24日採納及批准的H股獎勵計劃，其主要條款載於日期 | | --- | --- | --- | | | | 為2022年5月26日的通函 | | 「A股」 | 指 | 本公司已發行每股面值人民幣1.00元的普通股，將以人民幣認購或入賬列為 | | | | 已繳，並於上海證券交易所上市買賣 | | 「聯繫人」 | 指 | 具有上 ...

JOINN Laboratories (China) Co., Ltd. 北京昭衍新藥研究中心股份有限公司 (A joint stock company incorporated in the People's Republic of China with limited liability) （於中華人民共和國註冊成立的股份有限公司） （Stock Code 股份代號：6127） NOTIFICATION LETTER 通知信函 Dear Non-Registered Shareholders, JOINN Laboratories (China) Co., Ltd. (the "Company") – Notice of publication of 2025 Interim Report (the "Current Corporate Communication") The English and Chinese versions of the Company's Current Corporate Communications are available on the Company's websit ...

If you have difficulty in receiving email notification or gaining access to the Website Version of the Corporate Communications and would like to receive the Current Corporate Communication and all future Corporate Communications in printed form, please complete, sign the enclosed Reply Form and return it to the Company's H share registrar in Hong Kong, Tricor Investor Services Limited ("H Share Registrar") at 17/F, Far East Finance Centre, 16 Harcourt Road, Hong Kong by post using the provided prepaid mail ...

目錄 | 釋義 | 2 | | --- | --- | | 技術詞彙 | 5 | | 公司資料 | 6 | | 財務概要 | 8 | | 主席報告 | 9 | | 管理層討論及分析 | 10 | | 企業管治及其他資料 | 29 | | 未經審核綜合損益及其他全面收益表 | 40 | | 未經審核綜合財務狀況表 | 42 | | 未經審核綜合權益變動表 | 44 | | 未經審核綜合現金流量表 | 46 | | 未經審核中期財務報告附註 | 47 | 釋義 於本報告內，除文義另有所指外，下列詞彙具有以下涵義。該等詞彙及其定義未必與任何業內標準定義相符，亦未必 可直接與其他在本公司相同行業內經營的公司所採用的同類詞彙比較。 | 「2022年H股激勵計劃」 | 指 | 本公司於2022年6月24日採納及批准的H股獎勵計劃，其主要條款載於日期 | | --- | --- | --- | | | | 為2022年5月26日的通函 | | 「A股」 | 指 | 本公司已發行每股面值人民幣1.00元的普通股，將以人民幣認購或入賬列為 | | | | 已繳，並於上海證券交易所上市買賣 | | 「聯繫人」 | 指 | 具有上 ...

Core Viewpoint - The announcement of a 100% tariff on patented and branded drugs by the Trump administration starting October 1, 2025, aims to pressure pharmaceutical companies to relocate production to the U.S. [1] Market Reaction - Global pharmaceutical stocks, including Pfizer and Merck, experienced declines of over 2% in the U.S. market, while related stocks in A-shares and Hong Kong also fell significantly, impacting companies like Kanglong Chemical and Kylin Pharmaceutical [3] Policy Background - The tariff policy is not sudden; it has been hinted at since April, with escalating threats of high tariffs on imported drugs. Economists warn that such high tariffs could disrupt supply chains and potentially increase drug prices for U.S. consumers [4] Impact on Chinese Pharmaceutical Companies - Chinese innovative pharmaceutical companies face both challenges and opportunities. Short-term market volatility is expected, but the established global competitiveness of Chinese firms may allow them to adapt by accelerating overseas production to avoid tariffs [5] Industry Outlook - The fundamental drivers of innovative drug development remain unchanged despite national policies. China's pharmaceutical industry is transitioning from a "big pharmaceutical country" to an "innovative pharmaceutical powerhouse," with significant advancements in cutting-edge fields like stem cell and gene therapy [6]