集体业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： ? 会议召开时间：2025 年 9 月 16 日（星期二）15:00-17:00 证券代码：688098 证券简称：申联生物 公告编号：2025-034 申联生物医药（上海）股份有限公司 关于参加 2025 年半年度科创板创新药行业 ? 会议召开地点：上海证券交易所上证路演中心（网址：https://roadshow. sseinfo.com/） ? 会议召开方式：上证路演中心网络文字互动 ? 投资者可于 2025 年 9 月 9 日（星期二）至 9 月 15 日（星期一）16:00 前登录上证路演中心网站首页点击"提问预征集"栏目或通过公司邮箱 slsw@sl bio.com.cn 进行提问。公司将在说明会上对投资者普遍关注的问题进行回答。 申联生物医药（上海）股份有限公司（以下简称"公司"）已于 2025 年 8 月 30 日发布公司 2025 年半年度报告，为便于广大投资者更全面深入地了解公司 年度科创板创新药行业集体业绩说明会，就投资 ...

Market Overview - The animal health sector experienced a decline of 2.2% on September 3, with the leading stock, Driveline, falling by 8.33% [1] - The Shanghai Composite Index closed at 3813.56, down 1.16%, while the Shenzhen Component Index closed at 12472.0, down 0.65% [1] Stock Performance - Key stocks in the animal health sector showed significant declines, with Driveline (code: 838275) closing at 11.23, down 8.33% on a trading volume of 49,500 shares and a transaction value of 57.66 million yuan [1] - Other notable declines included: - Yongshun Biological (code: 839729) down 4.78% to 10.16 [1] - Jinhai Biological (code: 002688) down 4.03% to 6.91 [1] - ST Lvkang (code: 002868) down 3.30% to 26.35 [1] - Houbang Holdings (code: 002141) down 3.24% to 3.88 [1] Capital Flow - The animal health sector saw a net outflow of 108 million yuan from major funds, while retail investors contributed a net inflow of 101 million yuan [1] - Detailed capital flow for specific stocks indicated: - Shunlian Biological (code: 688098) had a net inflow of 8.21 million yuan from major funds [2] - ST Lvkang (code: 002868) experienced a net outflow of 2.26 million yuan from major funds [2] - Houbang Holdings (code: 002141) faced a significant net outflow of 24.59 million yuan from major funds [2]

重要内容提示： 会议召开时间：2025 年 9 月 16 日（星期二）15:00-17:00 会议召开地点：上海证券交易所上证路演中心（网址：https://roadshow. sseinfo.com/） 会议召开方式：上证路演中心网络文字互动 投资者可于 2025 年 9 月 9 日（星期二）至 9 月 15 日（星期一）16:00 前登录上证路演中心网站首页点击"提问预征集"栏目或通过公司邮箱 slsw@sl bio.com.cn 进行提问。公司将在说明会上对投资者普遍关注的问题进行回答。 申联生物医药（上海）股份有限公司（以下简称"公司"）已于 2025 年 8 月 30 日发布公司 2025 年半年度报告，为便于广大投资者更全面深入地了解公司 2025 年半年度经营成果、财务状况及战略布局创新药进展等情况，公司计划于 2 025 年 9 月 16 日（星期二）15:00-17:00 参加由上海证券交易所举办的 2025 年半 年度科创板创新药行业集体业绩说明会，就投资者关心的问题进行交流。 一、说明会类型 证券代码：688098 证券简称：申联生物 公告编号：2025-034 申联生物医药（上海）股份 ...

Core Viewpoint - The animal health sector experienced a decline of 2.73% on September 2, with Shunlian Biological leading the drop [1][2]. Market Performance - The Shanghai Composite Index closed at 3858.13, down 0.45% - The Shenzhen Component Index closed at 12553.84, down 2.14% [1]. Individual Stock Performance - Notable gainers included: - Qudongli (code: 838275) with a closing price of 12.25, up 3.38% on a trading volume of 52,700 shares and a turnover of 63.41 million yuan - Yongshun Biological (code: 839729) with a closing price of 10.67, up 1.62% on a trading volume of 36,800 shares and a turnover of 38.93 million yuan - Significant decliners included: - Shunlian Biological (code: 688098) with a closing price of 11.79, down 6.43% on a trading volume of 169,400 shares and a turnover of 203 million yuan - Jinhe Biological (code: 002688) with a closing price of 7.20, down 4.38% on a trading volume of 527,700 shares and a turnover of 382 million yuan [1][2]. Capital Flow Analysis - The animal health sector saw a net outflow of 259 million yuan from institutional investors, while retail investors contributed a net inflow of 199 million yuan [2][3]. - Key stocks with significant capital flow include: - Qianhe Biological (code: 002688) with a net outflow of 67.31 million yuan from institutional investors - Shunlian Biological (code: 688098) with a net outflow of 26.38 million yuan from institutional investors [3].

Group 1 - Weisheng Information won four projects in August with a total amount of 85.5377 million yuan, accounting for 3.12% of the company's total revenue for 2024 [1] - Longqi Technology's shareholder plans to reduce its stake by up to 4.09%, equating to a maximum of 19.1916 million shares [1] - Guojin Modern's subsidiary received a drug registration certificate for injectable Nicardipine, used for treating unstable angina [3][4] Group 2 - SAIC Motor reported a total vehicle sales of 363,400 units in August, a year-on-year increase of 41.04%, with new energy vehicle sales reaching 129,800 units, up 49.89% [5] - Kuka Home plans to invest 1.124 billion yuan to build a self-owned base in Indonesia, aiming to enhance its international strategy [6] - Samsung Medical's subsidiary signed a contract for an intelligent meter project in Egypt worth 58.8 million USD, approximately 419 million yuan [8] Group 3 - North Vehicle Blue Valley's subsidiary reported a total production of 10,587 units in August, a year-on-year decrease of 15.13%, while sales increased by 3.47% [12] - Xianghe Industrial signed contracts worth 400 million yuan for railway fastener system components [13] - Hengrui Medicine's HRS9531 injection has received acceptance for its marketing authorization application [14] Group 4 - Hualu Hengsheng resumed normal production after completing maintenance on production facilities [16] - Shanghai Pharmaceuticals' hydrochloride verapamil injection passed the consistency evaluation for generic drugs [18] - Shanghai Construction received approval for debt financing tools with a registration period of two years [20] Group 5 - Kangli Elevator terminated the sale of its wholly-owned subsidiary due to the buyer's failure to obtain necessary approvals [21] - Times Wan Heng appointed Li Zhizhong as the new deputy general manager [22] - Hanma Technology reported a total truck sales of 1,051 units in August, a year-on-year increase of 58.05% [24] Group 6 - Wenzhou Hongfeng's subsidiary received a utility model patent certificate for a servo adjustment device [26] - Yibin Technology received a project designation from a domestic new energy vehicle company, with an estimated total sales of 243 million yuan over five years [28] - Star Ring Technology's H-share issuance application was accepted by the China Securities Regulatory Commission [30] Group 7 - Microchip Bio's vice president resigned for personal reasons [31] - Zhongxin Co. announced the resignation of a non-independent director due to personal reasons [32] - Changcheng Military Industry's vice chairman resigned due to retirement [35] Group 8 - Jiukang Bio received four invention patent certificates related to detection reagents [36] - Meino Bio's subsidiary changed its registered address [37] - Kuangda Technology announced a potential change in control due to a share transfer [38] Group 9 - China Rare Earth confirmed no undisclosed significant matters amid stock price fluctuations [72]

Market Overview - The animal health sector increased by 1.34% on September 1, with Jinhe Biology leading the gains [1] - The Shanghai Composite Index closed at 3875.53, up 0.46%, while the Shenzhen Component Index closed at 12828.95, up 1.05% [1] Stock Performance - Jinhe Biology (002688) closed at 7.53, up 6.06% with a trading volume of 875,700 shares and a turnover of 651 million yuan [1] - Other notable performers included *ST Lvkang (002868) with a 5.02% increase, and Shunlian Biology (688098) with a 1.78% increase [1] - The overall trading data for the animal health sector is summarized in the provided table [1] Capital Flow - The animal health sector saw a net inflow of 26.58 million yuan from institutional investors, while retail investors experienced a net outflow of 7.06 million yuan [2] - The detailed capital flow for individual stocks indicates varying levels of institutional and retail participation [3] Individual Stock Analysis - Jinhe Biology had a net inflow of 88.59 million yuan from institutional investors, while retail investors showed a net outflow of 37.91 million yuan [3] - Other stocks like Kexin Biology (688526) and *ST Lvkang (002868) also experienced mixed capital flows, with significant retail outflows [3]

Group 1 - The company has received an update on the progress of the innovative drug UB-221's Phase II clinical research from its associate company, Yangzhou Shizhi Source Biotechnology Co., Ltd. [1] - UB-221 is a humanized monoclonal antibody developed by the inventor of the anti-IgE therapy, Dr. Zhang Ziwen, and is designed to treat allergic reactions by neutralizing free IgE and inhibiting its synthesis [2][1]. - The ongoing Phase II clinical trial is a multi-center, randomized, double-blind, placebo-controlled study aimed at evaluating the efficacy and safety of UB-221 in patients with chronic spontaneous urticaria (CSU), with a target enrollment of 144 patients, ultimately recruiting 145 [2]. Group 2 - The company is focused on building a world-class high-tech biopharmaceutical company and is actively expanding its business into the human innovative drug sector, leveraging its diverse biopharmaceutical technology platforms and talent reserves [3]. - The company is advancing the development of three innovative drugs: UB-221, UB-421, and UB-621, while also exploring new indications, supported by its technological expertise in synthetic peptides, genetic engineering, and mRNA [3].

申联生物8月31日公告，公司近日收到参股公司世之源关于创新药UB-221注射液II期临床研究进展的 《告知函》，截至本公告披露日，该项目已完成全部145例受试者入组。世之源拥有UB-221在中国大陆 的上市许可和研发、生产、销售等全部商业化权益。UB-221是由公司第二大股东美国联合生物医学公 司（United Biomedical, Inc., UBI）原研研发，该项目由anti-IgE治疗法发明人张子文博士开发的次世代 产品，是皮下注射剂型的人源化原研单抗。 ...

申联生物医药（上海）股份有限公司（以下简称"公司"）近日收到参股公 司扬州世之源生物科技有限责任公司（以下简称"世之源"）关于创新药 UB-221 注射液 II 期临床研究进展的《告知函》，截至本公告披露日，该项目已完成全部 145 例受试者入组。现将相关情况公告如下： 一、UB-221 基本情况介绍 世之源拥有 UB-221 在中国大陆的上市许可和研发、生产、销售等全部商业 化权益。UB-221 是由公司第二大股东美国联合生物医学公司（United Biomedical, Inc., UBI）原研研发，该项目由 anti-IgE 治疗法发明人张子文博士开发的次世代 产品，是皮下注射剂型的人源化原研单抗。 UB-221 不仅可同时中和引发过敏反应的游离 IgE，亦能透过结合至 B 细胞 表面的 CD23 受体结合的 IgE 而抑制 IgE 的合成。临床前资料充分证明 UB-221 具有比同类已上市的产品更加优越的药理学特征：UB-221 不仅可中和游离 IgE， 抑制 IgE 生成；UB-221 中和游离 IgE 的效果更好；UB-221 阻断 IgE 生成的效果 更优；在食蟹猴和人类 IgE(ε,κ）基因转 ...

Group 1 - The company received a notification regarding the progress of the Phase II clinical trial for the innovative drug UB-221, which has completed the enrollment of all 145 participants [1] - The clinical trial is a Phase II, multi-center, randomized, double-blind, placebo-controlled study aimed at evaluating the efficacy and safety of UB-221 in patients with chronic spontaneous urticaria (CSU) [1] - The trial planned to recruit 144 patients but ultimately enrolled 145, with participants randomly assigned to one of five treatment groups [1] Group 2 - The company is focused on building a world-class high-tech biopharmaceutical company, leveraging its diverse biopharmaceutical technology platform and talent pool to expand its business boundaries [2] - The company is actively developing three innovative drugs: UB-221, UB-421, and UB-621, while also exploring new indications for these drugs [2] - The company aims to transition from animal health to human pharmaceuticals by utilizing its technological expertise in synthetic peptides, genetic engineering, and mRNA, alongside its capabilities in innovative drug development management [2]