根据《中华人民共和国公司法》《上市公司股份回购规则》《深圳证券交易 所上市公司自律监管指引第 9 号—回购股份》的相关规定，上市公司回购专用 账户中的股份不享有利润分配、公积金转增股本等权利。因此，普洛药业股份有 限公司（以下简称"公司"）回购专用证券账户中 11,065,000 股不参与此次分 红派息。 公司 2024 年度利润分配和资本公积金转增股本方案已获 2025 年 4 月 17 日 召开的 2024 年年度股东大会审议通过，现将分红派息事宜公告如下： 一、股东大会审议通过利润分配方案情况 1、公司 2024 年年度股东大会审议通过的利润分配方案为：以 2024 年末总 股本 1,169,323,576 股扣减公司回购专用证券账户中股份 10,880,000 股后的股 本 1,158,443,576 为基数，向全体股东每 10 股派发现金红利 3.56 元（含税）， 共计派发现金红利 412,405,913.06 元（含税）,不送红股，也不以资本公积金转 增股本。利润分配方案公布后至实施前，如公司总股本由于可转债转股、股份回 购、股权激励行权、再融资新增股份上市等原因发生变动，按照"现金分红总额 不 ...

Group 1: Industry Overview - The overall revenue growth rate for the pharmaceutical and biotechnology sector in Q1 2025 was -4.8%, with a net profit growth rate of -12.2%[3] - The raw material drug sector showed resilience with a revenue growth rate of -3.6% and a net profit growth rate of 10.5% in Q1 2025, benefiting from demand recovery and price stabilization[3] Group 2: Profitability and Financial Performance - In 2024, major raw material drug companies saw an increase in gross margin and net margin by 0.78 percentage points and 0.39 percentage points respectively, while Q1 2025 saw a decline in average gross margin and net margin by 0.64 percentage points and 1.87 percentage points respectively[5] - The average operating cash flow for major raw material drug companies reached 10.04 billion yuan in 2024, a 14.65% increase from 2023, indicating a positive trend[31] Group 3: Capital Expenditure Trends - Capital expenditure for major raw material drug companies in 2024 totaled 7.242 billion yuan, reflecting a year-over-year decrease of 4.12%[36] - The capital expenditure to depreciation ratio for the raw material drug sector decreased from 1.79 in 2023 to 1.27 in 2024, indicating ongoing capacity reduction and structural adjustments[36] Group 4: Investment Strategy - Investment recommendations focus on selecting raw material drug companies with strong growth attributes and stable competitive landscapes, particularly in bulk and specialty raw materials[44] - Companies like Guobang Pharmaceutical and Tianyu Co., Ltd. are highlighted for their favorable supply dynamics and demand recovery[44] Group 5: Risk Factors - Risks include intensified competition leading to suboptimal recovery in product prices and volumes, production safety incidents, and exchange rate fluctuations impacting profitability[47]

Investment Rating - The report indicates a positive outlook for the pharmaceutical raw materials sector, highlighting a significant profit growth in Q1 and an expected improvement in industry supply and demand dynamics [3][4]. Core Insights - The pharmaceutical raw materials sector experienced a revenue of CNY 1176.77 billion in 2024, a year-on-year increase of 6.74%, with a net profit of CNY 150.46 billion, reflecting a growth of 27.89% [3][4][21]. - In Q1 2025, the sector's revenue was CNY 295.46 billion, a slight decline of 0.48% year-on-year, but net profit increased by 20.87% to CNY 45.62 billion [3][4][21]. - The report emphasizes that the rapid profit growth is attributed to several factors, including a low base in H2 2023, the end of inventory destocking by global downstream manufacturers, and improved product pricing stability [3][4][21][23]. Summary by Sections Q1 Performance - The raw materials sector's revenue was stable year-on-year, with a slight decline in Q1 2025 compared to the previous year, while profits showed significant growth [3][4][21]. - The sector's gross margin improved to 38.14% in Q1 2025, up 1.76 percentage points year-on-year, and the net margin reached 15.41%, an increase of 2.63 percentage points [4][25]. Industry Concentration - The top 10 companies in the raw materials sector contributed over 73% of total revenue in 2024, with significant contributions from companies like New and Cheng and Pro Pharmaceutical [31][33]. - In Q1 2025, the top 10 companies accounted for 73.19% of total revenue, indicating a slight decrease in concentration compared to the previous year [33][34]. Valuation and Construction Projects - The report notes that the valuation of the raw materials sector remains at historical lows, with a PE ratio of 30.26x at the end of 2024 and 33.97x at the end of Q1 2025 [5][42]. - The total construction projects in the sector decreased to CNY 163.57 billion by Q1 2025, reflecting a decline of 4.31% year-on-year, indicating a slowdown in capacity expansion [9][44]. Investment Recommendations - The report suggests focusing on companies with strong performance certainty in the formulation and CDMO sectors, such as Aorite and Pro Pharmaceutical, as well as those with significant new product contributions [10][38]. - It highlights the potential for increased demand for raw materials due to the expiration of patents for top-selling small molecule drugs in the coming years [6][42].

Group 1 - The World Health Organization (WHO) plans to include weight loss medications in its essential medicines list for treating adult obesity, with guidelines expected to be released in August or September [1] - The current review by WHO's expert committee aims to provide guidance for national or regional procurement agencies to select medications that meet priority health needs [1] - The global public health policy is undergoing a significant shift in addressing the obesity epidemic [1] Group 2 - As domestic weight loss drugs approach commercialization, sales capability will be a critical factor in determining future competitive advantages for companies [2] - Companies with leading research and development progress and strong sales execution will hold advantageous positions in the commercialization competition [2] - The entire GLP-1 industry chain is expected to enter a phase of increasing prosperity due to sustained growth in end-user demand [2] Group 3 - Pro Pharmaceutical's research on the peptide-based weight loss drug (semaglutide injection) is progressing smoothly [3] - Borui Pharmaceutical has developed a dual receptor agonist (GLP-1/GLP) that can control blood sugar, promote weight loss, and treat non-alcoholic fatty liver disease [4] Group 4 - The competition in the global weight loss drug market is intensifying, particularly between Novo Nordisk and Eli Lilly [1] - Future sales performance in the weight loss drug market may not solely depend on clinical data, as Novo Nordisk's superior marketing strategies play a significant role [1] - Novo Nordisk's marketing efforts include substantial investments in promotional activities and the use of more engaging narrative scenarios [1]

证券代码：000739 证券简称：普洛药业 公告编号：2024-29 普洛药业股份有限公司 二、其他说明 关于首次回购公司股份暨回购股份的进展公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 普洛药业股份有限公司（以下简称"公司"）于2025年2月19日召开第九届 董事会第十次会议审议通过了《关于回购公司股份方案的议案》，同意公司使用 自有资金以集中竞价交易方式回购公司部分股份，用于实施公司股权激励和员工 持股计划。本次回购股份价格不超过人民币22元/股（含），回购资金总额不低 于人民币7,500万元（含）且不超过人民币15,000万元（含）。具体回购股份数 量以回购期限届满或回购股份实施完毕时实际回购股份数量为准。回购期限为自 公司董事会审议通过回购股份方案之日起12个月内。具体内容详见公司分别于 2025 年 2 月 20 日 、 2025 年 2 月 21 日 在 《 证 券 时 报 》 和 巨 潮 资 讯 网 （http://www.cninfo.com.cn）上披露的《第九届董事会第十次会议决议公告》 （公告编号：2025-04）、《关于回购公司 ...

3、2025 年 4 月 7 日，公司与中国银行股份有限公司东阳支行（以下简称"中 国银行"）签订《保证合同》（合同编号：横店 2025 人保字 067 号），同意为 公司全资子公司家园药业与中国银行签署的《流动资金借款合同》（合同编号： 横店 2025 人借字 067 号）中的流动资金贷款 10,000 万元提供连带责任保证，担 保期限 7 个月。 4、2025 年 4 月 27 日，公司与中国农业银行股份有限公司东阳市支行（以 下简称"农业银行"）签订《保证合同》（合同编号：33100120250006466）， 同意为公司控股子公司浙江普洛康裕制药有限公司（以下简称"普洛康裕"）与 农业银行签署的《商业汇票银行承兑合同》（合同编号：331801202540012156） 中的 1,230 万元银行承兑汇票提供连带责任保证，担保期限 6 个月。 证券代码：000739 证券简称：普洛药业 公告编号：2025-28 普洛药业股份有限公司 关于对下属公司担保的进展公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 一、担保情况概述 1、2025 年 3 月 ...

Core Insights - The global and US innovative drug VC&PE financing amounts are expected to grow by 1.93% and 5.29% respectively in 2024, indicating a recovery in the innovative drug financing environment [1] - The demand for research and development in fields such as peptides and ADCs is strong, leading to an increase in outsourcing needs in these areas [1][2] Macro Perspective - The global innovative drug financing environment is recovering, with significant growth in the demand for innovative research in specific fields like peptides and ADCs, which is expected to enhance the CXO industry's outlook [1] - According to Crunchbase, the VC&PE financing for innovative drugs in 2024 shows positive growth, marking an improvement in the financing environment [1] Micro Perspective - CXO listed companies are seeing a recovery in new orders, with many companies like WuXi AppTec, WuXi Biologics, and others reporting a year-on-year increase of over 20% in new orders [3] - The production capacity of domestic CXO companies is mature, ensuring timely delivery of orders, which is expected to lead to double-digit revenue growth for several companies in 2025 [3] Target Companies - Recommended companies to watch include WuXi AppTec (603259.SH, 02359), WuXi Biologics (02269), WuXi AppTec (02268), Kelun Pharmaceutical (002821.SZ, 06821), and others [4]

第九届董事会第十三次会议决议公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 普洛药业股份有限公司（以下简称"公司"）第九届董事会第十三次会议通 知于 2025 年 4 月 15 日以电子邮件的方式发出。会议于 2025 年 4 月 25 日以现场 会议的方式召开，会议应到董事 7 人，实到董事 7 人。会议由公司董事长祝方猛 先生主持，公司 3 名监事及 5 位高管列席了会议。本次会议的召开符合《公司法》 和《公司章程》的有关规定。出席会议的董事经过审议表决，通过了以下议案： 证券代码：000739 证券简称：普洛药业 公告编号：2025-26 普洛药业股份有限公司 表决结果：同意票 7 票，反对票 0 票，弃权票 0 票。 特此公告。 普洛药业股份有限公司董事会 2025 年 4 月 25 日 一、审议通过《关于增加回购股份资金来源的议案》 ...

证券代码：000739 证券简称：普洛药业 公告编号：2025-27 普洛药业股份有限公司 关于增加回购股份资金来源的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 重要内容提示： 1、公司本次回购股份的资金来源由"自有资金"调整为"自有资金及金融 机构借款"。除上述调整外，回购股份方案的其他内容未发生变化。 2、本次调整回购股份资金来源事项已经公司第九届董事会第十三次会议审 议通过，无需提交股东大会审议。 3、本次股票回购专项贷款额度不代表公司对回购金额的承诺，具体回购股 份的金额以回购完毕或回购实施期限届满时公司的实际回购情况为准。 一、本次回购股份的基本情况 普洛药业股份有限公司（以下简称"公司"）于 2025 年 2 月 19 日召开第 九届董事会第十次会议审议通过了《关于公司回购股份方案的议案》，公司拟 使用自有资金以集中竞价交易方式回购公司股份，用于实施股权激励或员工持股 计划。回购股份价格不超过人民币 22 元/股，回购资金总额不低于人民币 7,500 万元（含）且不超过人民币 15,000 万元（含）。在回购价格不超过人民币 22 元/股 ...

Group 1 - The core viewpoint of the article highlights the recent research conducted by Shanghai Chengrui Investment on a listed company, Puluo Pharmaceutical, which is planning a third share buyback plan by 2025 and is currently processing related procedures [1] - Puluo Pharmaceutical's cephalosporin product prices have decreased by approximately 15%, while penicillin product prices remain stable, and the price of florfenicol is expected to rebound in the third quarter [1] - The company's CDMO business is projected to grow by 20%-30% with a gross margin of 40%-45%, while the raw material drug business faces pressure with a slight decline in sales volume, controlling gross margin contribution to within 10% [1] - New products such as ferrous fumarate chewable tablets are expected to drive growth, alongside the release of older products like levetiracetam and succinic acid metoprolol [1] - The company has completed the enrollment for the third phase of the clinical trial for the weight loss project of semaglutide, with 40% enrollment progress for the diabetes indication [1] - Puluo Pharmaceutical has established a digital innovation team to utilize AI for optimizing fermentation processes, significantly enhancing fermentation efficacy [1] Group 2 - Shanghai Chengrui Investment, established in May 2010, has a registered capital of 110 million and has been recognized for its stable development and diverse client base, including banks, private banks, and various institutional investors [2] - The company has a professional investment research team of 33 members, with backgrounds from prestigious universities both domestically and internationally [2] - Chengrui Investment has received multiple awards and recognitions over the years, including being listed among the top private equity funds in China and winning various industry awards for its performance [2]