"以生产经营成本与市场供求状况为定价基本依据，依法自主合理定价，自觉维护市场价格稳定，共同营 造公平有序的竞争环境。"近日，行业协会发声"反内卷"，疫苗市场激烈竞争再次走到台前。 中国疫苗行业协会倡议，坚决抵制无序低价竞争，在招投标全流程中，严禁以低于成本的报价参与竞标， 切实保障产品与服务的质量标准。而本倡议经理事会批准后，全体会员应共同遵守，并接受行业与社会监 督。如有违反，将受到全体会员的集体谴责，本会将给予其警告、通报批评、暂停行使会员权利直至除名 等措施。 近年来，二价HPV疫苗、流感疫苗接连打响价格战，竞争白热化也使得业绩承压。新京报贝壳财经记者根 据Wind数据统计发现，今年前三季度，A股14家主要疫苗上市公司中，仅4家的归母净利润实现了同比增 长，与此同时，仅5家企业实现营收同比增长。 价格战战火很快蔓延至流感疫苗。2024年5月，国药集团下属长春生物制品研究所、武汉生物制品研究 所、上海生物制品研究所、华兰疫苗、北京科兴等企业相继宣布下调四价流感疫苗价格。 其中，长春生物制品研究所、武汉生物制品研究所、上海生物制品研究所四价流感病毒裂解疫苗中标价格 从128元/支降到88元/支，价格降幅达3 ...

11月21日，智飞生物跌3.58%，成交额5.71亿元。两融数据显示，当日智飞生物获融资买入额6306.08万 元，融资偿还7955.32万元，融资净买入-1649.23万元。截至11月21日，智飞生物融资融券余额合计 13.87亿元。 截至11月10日，智飞生物股东户数13.31万，较上期增加1.19%；人均流通股10624股，较上期减少 1.17%。2025年1月-9月，智飞生物实现营业收入76.27亿元，同比减少66.53%；归母净利润-12.06亿元， 同比减少156.10%。 分红方面，智飞生物A股上市后累计派现73.18亿元。近三年，累计派现31.94亿元。 机构持仓方面，截止2025年9月30日，智飞生物十大流通股东中，香港中央结算有限公司位居第三大流 通股东，持股3356.08万股，相比上期减少278.88万股。易方达创业板ETF（159915）位居第五大流通股 东，持股2415.90万股，相比上期减少405.65万股。华泰柏瑞沪深300ETF（510300）位居第六大流通股 东，持股2042.08万股，相比上期减少96.46万股。招商国证生物医药指数A（161726）位居第九大流通 股东，持 ...

以下文章来源于雷达Finance ，作者X编辑 雷达Finance . 遨游广袤的财富世界。 放眼前三季度，智飞生物的经营情况依旧不容乐观，公司实现76.27亿元的营收，同比减少66.53%；录得归母净利润亏损12.06亿元，同比由盈转 亏。 导语：智飞生物曾经赖以盈利的"摇钱树"产品吸金能力大幅减弱。 在近日揭晓的《2025胡润百富榜》上，智飞生物的蒋仁生家族凭借420亿元的身家再度问鼎重庆首富（以居住地为标准）。 尽管其财富规模较上一年度增长4%，但与2021年高达1400亿元的身家相比却缩水近千亿元。 在一众重庆富豪中，赛力斯母公司小康控股的张兴海、颜敏夫妇以360亿元的财富紧随蒋仁生家族之后，且其身家较去年实现了高达八成的迅猛增 长。 蒋仁生家族财富地位面临挑战的背后，是智飞生物近年来不尽如人意的业绩表现。近日，公司更是交出一份难言出色的三季报：前三季度，公司营 收骤降66.53%，归母净利润更是自上市以来同期首次转负。 有分析认为，随着国内HPV疫苗市场逐渐趋于饱和，智飞生物曾经赖以盈利的"摇钱树"产品吸金能力大幅减弱。而被公司寄予厚望的重组带状疱疹 疫苗，目前市场表现平平。 反映到资本市场，截至1 ...

在近日揭晓的《2025胡润百富榜》上，智飞生物的蒋仁生家族凭借420亿元的身家再度问鼎重庆首富（以居住地为标准）。 尽管其财富规模较上一年度增长4%，但与2021年高达1400亿元的身家相比却缩水近千亿元。 在一众重庆富豪中，赛力斯母公司小康控股的张兴海、颜敏夫妇以360亿元的财富紧随蒋仁生家族之后，且其身家较去年实现了高达八成的迅猛增长。 蒋仁生家族财富地位面临挑战的背后，是智飞生物近年来不尽如人意的业绩表现。近日，公司更是交出一份难言出色的三季报：前三季度，公司营收骤降 66.53%，归母净利润更是自上市以来同期首次转负。 有分析认为，随着国内HPV疫苗市场逐渐趋于饱和，智飞生物曾经赖以盈利的"摇钱树"产品吸金能力大幅减弱。而被公司寄予厚望的重组带状疱疹疫苗， 目前市场表现平平。 反映到资本市场，截至11月21日收盘，智飞生物的股价为20.19元/股，总市值为483亿元，较2021年巅峰时期减少超3000亿元。 营收利润双降，前三季度亏12亿 据智飞生物最新发布的财报，今年第三季度，公司的业绩全面承压，不仅营收同比减少四成至27.05亿元，归母净利润更是暴跌556.79%，录得亏损6.01亿 元。 放眼前 ...

【#带状疱疹及九价HPV疫苗促销席卷多地# 多家企业参与】九价HPV与带状疱疹疫苗在国内多个省市 地区已开展促销，让利幅度从最低3折到"打一送一"不等，参与企业包括智飞生物、百克生物等。有参 与促销的企业表示，"这是惠民降价，主要为配合加强公众疾病预防意识等。"但也有业内人士告诉智通 财经记者，当前一些头部疫苗企业存货数量较多，因为存在有效期，促销是减少库存的最佳手段。（智 通财经） ...

Core Insights - The promotion of nine-valent HPV and shingles vaccines has been initiated in various provinces and cities in China, with discounts ranging from 30% to "buy one get one free" [1] - Participating companies include Zhifei Biological and Baike Biological, indicating a competitive market environment [1] - The promotions are aimed at enhancing public awareness of disease prevention, although some industry insiders suggest that high inventory levels among leading vaccine companies are driving these promotional efforts [1] Company Insights - Zhifei Biological and Baike Biological are actively participating in the promotional campaigns, reflecting their strategies to boost sales and market presence [1] - The promotional activities may indicate a shift in pricing strategies within the vaccine sector, as companies seek to attract more consumers [1] Industry Insights - The current promotional efforts highlight a trend in the vaccine industry towards price reductions and increased accessibility for consumers [1] - The presence of significant inventory among leading vaccine manufacturers suggests potential challenges in inventory management and product expiration [1]

HPV疫苗价格降至一杯奶茶钱，流感疫苗甚至跌至个位数……在疫苗行业愈发"内卷"的当下，中国疫苗 行业协会发声，倡议协会会员坚决抵制无序低价竞争，严禁以低于成本的报价参与竞标。目前，中国疫 苗行业协会会员达到334家，主要疫苗厂商均涵盖在内。 疫苗行业的价格战，也使相关企业业绩出现承压，今年前三季度，A股14家疫苗企业中，有10家企业归 属净利润同比出现下滑，其中万泰生物、百克生物、智飞生物等更是由盈转亏。在业内人士看来，上述 倡议若能有效落实，有助于遏制恶性价格战，稳定市场价格环境，从而减少企业利润压力，促进资源向 研发和创新倾斜。 严禁以低于成本报价参与竞标 11月19日，中国疫苗行业协会发布《关于反对"内卷式"竞争 促进疫苗及其相关生物制品行业高质量发 展的倡议》。中国疫苗行业协会表示，该倡议旨在通过强化自律、鼓励创新，助力行业打破"内卷"，构 建健康有序的良性生态，共同开启以质量、安全、创新为核心的行业发展新篇章。 倡议提到，中国疫苗行业协会全体会员须严格遵循《中华人民共和国疫苗管理法》《中华人民共和国价 格法》，严格遵守行业自律公约，坚持公平、合法、诚实信用原则，以生产经营成本与市场供求状况为 定价基 ...

Policy Developments - The National Medical Products Administration (NMPA) is focusing on the quality supervision of selected drugs in centralized procurement, emphasizing the importance of quality safety and compliance in production [1] - The NMPA will implement comprehensive production inspections and product sampling for selected drugs, optimizing work mechanisms and exploring risk monitoring [1] - The NMPA acknowledges the development of the medical device industry in Chongqing and stresses the need for a robust quality safety responsibility system [2] Drug and Device Approvals - Baiyunshan's subsidiary Zhongyi Pharmaceutical received a registration certificate for the traditional medicine An Gong Niu Huang Wan from Vietnam's Ministry of Health, aiding market expansion [3] - Huyou Pharmaceutical announced that its subsidiary Seacross Pharmaceuticals Ltd. received marketing approvals for multiple products from regulatory authorities in Pakistan, the UK, and North Macedonia [4] - Zhifei Biological's recombinant herpes zoster vaccine (ZFA01) clinical trial application has been accepted by the NMPA, which may enhance vaccine efficacy [5] Capital Market Activities - Puluo Pharmaceutical plans to repurchase shares worth between RMB 180 million and RMB 360 million, with a maximum price of RMB 23 per share [6][7] - Sinovac Biotech received a delisting notice from NASDAQ due to failure to submit its annual report by the deadline, with potential trading suspension imminent [8] Industry Developments - Researchers published a detailed immune response map following pig kidney transplants in brain-dead patient models, identifying key factors for transplant success [9] - Haizheng Pharmaceutical's subsidiary plans to collaborate with the East China Institute for the biomanufacturing of heparin, with a project budget not exceeding RMB 120 million [10] Public Sentiment Alerts - Guangyuyuan announced the resignation of Vice President Wang Junbo due to work adjustments, effective immediately [11] - Medici's shareholder Chen Guoxing plans to reduce his stake by up to 1.64% through trading methods due to personal financial needs [12]

Core Viewpoint - The Chinese Vaccine Industry Association has issued an initiative to combat "involution" competition in the vaccine sector, aiming to promote high-quality development and establish a healthy competitive environment in the industry [1][2]. Group 1: Initiative Details - The initiative mandates all members of the Chinese Vaccine Industry Association to adhere to the Vaccine Administration Law and the Price Law of the People's Republic of China, ensuring fair and legal pricing based on production costs and market demand [1]. - Members are required to resist disorderly low-price competition and are prohibited from participating in bidding with prices below cost, thereby ensuring product and service quality standards [1][2]. Group 2: Industry Context - The association currently has over 330 member units and 35 branches, encompassing major vaccine and biological product companies, as well as upstream and downstream service providers in the biopharmaceutical industry [4]. - A price war has emerged in the public market, with significant price drops observed. For instance, the bid price for a trivalent flu vaccine from Shanghai Biological Products Research Institute was set at 5.5 yuan per dose in September, marking a new low in the public flu vaccine market [4]. - The price of a bivalent HPV vaccine from Watson Bio was reduced to 27.5 yuan per dose in a procurement project, humorously compared to the cost of a cup of milk tea [4]. Group 3: Financial Impact - The price war reflects a phenomenon of homogenized competition within the industry, leading to financial pressure on vaccine companies. In the first three quarters of this year, 10 out of 14 listed vaccine companies reported a year-on-year decline in net profit [5]. - Notably, five companies, including Zhifei Biological Products and Kanglaite, reported significant losses, totaling over 12 billion yuan for Zhifei alone [5]. - Industry insiders have expressed concerns that some companies are engaging in price wars to survive or capture market share, hoping for further national measures to address the issue of "involution" [5].

Key Points - 合富中国's stock will resume trading on November 20 after completing an investigation into unusual trading fluctuations, confirming normal business operations and no undisclosed significant matters [1] - 中金公司 plans to merge with 东兴证券 and 信达证券, leading to a suspension of its A-shares starting November 20 due to uncertainties surrounding the merger [1] - 大为股份 is progressing with the transition from exploration to mining rights for its lithium battery project in Hunan, having received necessary approvals [1] - 燕东微's major shareholders plan to reduce their stakes by up to 2.5% through block trades or centralized bidding from December 11, 2025, to March 11, 2026 [2] - 中水渔业's major shareholder reduced its stake to 5% after selling 258.88 million shares [3] - 韵达股份 reported a slight decline in express service revenue for October 2025, totaling 4.495 billion yuan, a year-on-year decrease of 0.88% [4] - 倍杰特 intends to acquire a 55% stake in 大豪矿业 for 224.8 million yuan [4] - 辰奕智能 plans to acquire a 55% stake in 华泽电子 through cash [4] - 赣粤高速's actual controller will change from the provincial transportation department to the provincial state-owned assets supervision and administration commission [5] - 东软集团 received a notification for a 4.2 billion yuan contract for intelligent cockpit controllers from a major domestic automotive manufacturer [5] - 海正药业's subsidiary plans to invest in a pet prescription food project [5] - 龙利得's controlling shareholder plans to increase its stake by at least 56 million yuan [6] - 新兴装备's shareholders plan to reduce their stakes by up to 3.13% [6] - 普洛药业 plans to repurchase shares worth between 180 million and 360 million yuan [6]