Market Overview - As of 10:29 AM today, the Shanghai Composite Index stands at 3864.71 points, above the annual line, with a change of 0.18% [1] - The total trading volume of A-shares today is 138.21 billion yuan [1] Stocks Breaking Annual Line - A total of 41 A-shares have surpassed the annual line today, with notable stocks showing significant deviation rates [1] - The stocks with the highest deviation rates include: - Energy Iron Han (节能铁汉) with a deviation rate of 14.24% and a daily increase of 14.69% [1] - Qidi Environment (启迪环境) with a deviation rate of 7.10% and a daily increase of 10.26% [1] - ST Quanwei (ST泉为) with a deviation rate of 6.60% and a daily increase of 9.06% [1] Detailed Stock Performance - The following table summarizes the performance of selected stocks that have recently broken the annual line: | Stock Code | Stock Name | Daily Change (%) | Turnover Rate (%) | Annual Line (yuan) | Latest Price (yuan) | Deviation Rate (%) | | --- | --- | --- | --- | --- | --- | --- | | 300197 | 节能铁汉 | 14.69 | 5.66 | 2.12 | 2.42 | 14.24 | | 000826 | 启迪环境 | 10.26 | 8.19 | 2.01 | 2.15 | 7.10 | | 300716 | ST泉为 | 9.06 | 3.95 | 10.05 | 10.71 | 6.60 | | 001215 | 千味央厨 | 3.57 | 2.39 | 29.19 | 30.19 | 3.43 | | 601882 | 海天精工 | 5.10 | 1.67 | 20.52 | 21.02 | 2.45 | | 601298 | 青岛港 | 2.59 | 0.45 | 8.54 | 8.72 | 2.09 | | 002771 | 真视通 | 3.22 | 3.18 | 17.64 | 17.97 | 1.85 | | 600653 | 申华控股 | 2.56 | 1.44 | 1.97 | 2.00 | 1.76 | | 300141 | 和顺电气 | 1.77 | 1.04 | 9.07 | 9.22 | 1.63 | | 002390 | 信邦制药 | 2.75 | 1.17 | 3.68 | 3.73 | 1.46 | | 600189 | 泉阳泉 | 1.49 | 1.23 | 7.38 | 7.48 | 1.41 | | 601328 | 交通银行 | 1.51 | 0.53 | 7.28 | 7.38 | 1.40 | | 600518 | 康美药业 | 4.41 | 2.72 | 2.10 | 2.13 | 1.25 | | 300318 | 博晖创新 | 1.18 | 0.45 | 5.92 | 5.98 | 1.08 | | 300144 | 宋城演艺 | 1.49 | 1.35 | 8.82 | 8.88 | 0.72 | | 600916 | 中国黄金 | 1.83 | 2.15 | 8.27 | 8.33 | 0.71 | | 300067 | 安诺其 | 1.48 | 1.87 | 5.44 | 5.47 | 0.61 | | 600272 | 开开实业 | 1.36 | 1.09 | 13.39 | 13.45 | 0.48 | | 603310 | 巍华新材 | 0.61 | 0.69 | 17.96 | 18.05 | 0.47 | | 603718 | 海利生物 | 0.70 | 0.66 | 7.17 | 7.20 | 0.41 | | 603768 | 常青股份 | 0.95 | 0.80 | 12.72 | 12.76 | 0.35 | | 600062 | 华润双鹤 | 1.08 | 0.71 | 19.60 | 19.66 | 0.30 | | 300784 | 利安科技 | 2.40 | 3.84 | 56.62 | 56.78 | 0.29 | | 600236 | 桂冠电力 | 0.32 | 0.05 | 6.32 | 6.34 | 0.28 | | 300076 | GQY视讯 | 1.71 | 1.47 | 6.54 | 6.56 | 0.25 | | 601898 | 中煤能源 | 0.97 | 0.11 | 11.42 | 11.45 | 0.24 | [1]

Financial Performance - The company's total revenue for the first half of 2025 was 404 million yuan, a decrease of 17.03% year-on-year [1] - The net profit attributable to the parent company was -18.69 million yuan, down 167.63% year-on-year [1] - In Q2 2025, total revenue was 202 million yuan, a decline of 10.02% year-on-year, with a net profit of -14.63 million yuan, a drop of 288.33% [1] Key Financial Ratios - Gross margin was 39.71%, down 22.25% year-on-year, while net margin was -7.55%, a decrease of 165.20% [1] - The total of selling, administrative, and financial expenses reached 143 million yuan, accounting for 35.37% of revenue, an increase of 21.28% year-on-year [1] - Earnings per share were -0.02 yuan, a decline of 167.75% year-on-year, and operating cash flow per share was -0.06 yuan, down 388.83% [1] Balance Sheet Insights - Accounts receivable increased by 65.29% year-on-year, reaching 78.99 million yuan [1] - The company’s interest-bearing liabilities rose by 17.92% to 1.102 billion yuan [1] - Cash and cash equivalents amounted to 164 million yuan, an increase of 74.92% year-on-year [1] Historical Performance and Business Model - The company's return on invested capital (ROIC) was 1.09% last year, indicating weak capital returns [3] - The historical median ROIC over the past decade was 1.31%, with a significant drop to -26.03% in the worst year, 2021 [3] - The business model relies heavily on research and marketing, which requires careful examination of the underlying drivers [3] Cash Flow and Debt Analysis - Cash flow metrics indicate that cash and cash equivalents represent only 3.92% of total assets and 16.56% of current liabilities [3] - The interest-bearing debt ratio has reached 25.53%, with total interest-bearing liabilities at 23.78 times the average operating cash flow over the past three years [3] - Accounts receivable are 854.32% of profit, and inventory is 124.03% of revenue, suggesting potential liquidity issues [3]

Group 1 - The company BoHui Innovation announced the convening of its 8th Board of Directors meeting on August 27, 2025, to review the "2025 Semi-Annual Report" and its summary [1] Group 2 - The news highlights the world's first successful transplantation of gene-edited pig lungs into a human, raising questions about the timeline for clinical applications [1]

证券代码：300318 证券简称：博晖创新 公告编号：临 2025-032 北京博晖创新生物技术集团股份有限公司 关于计提资产减值准备及核销资产的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 北京博晖创新生物技术集团股份有限公司（以下简称"公司"或"博晖创新"） 于 2025 年 8 月 27 日召开第八届董事会第十三次会议和第八届监事会第十二次会 议，审议通过了《关于计提资产减值准备及核销资产的议案》，同意计提资产减 值准备及核销资产，其中，计提资产减值准备合计金额人民币 2,514,850.40 元； 核销资产合计金额人民币 2,678,304.72 元。现将具体情况公告如下： 一、本次计提资产减值准备基本情况 （一）本次计提资产减值准备概况 1、本次计提资产减值准备的原因 为真实反映公司财务状况和经营成果，公司依据《企业会计准则第8号—资 产减值》规定，基于谨慎性原则，对截至2025年6月30日公司及合并范围内各下 属公司所属资产进行了减值测试，判断存在减值的迹象，确定了需要计提减值准 备的资产项目。 2、本次计提资产减值准备的范围和金额 项目 ...

北京博晖创新生物技术集团股份有限公司 2025 年半年度非经营性资金占用及其他关联资金往来情况汇总表 单位：万元 注：①表中非经营性占用部分，关联方范围依照《创业板上市规则》确定。②无控股股东、实际控制人的公司，存在第一大股东或第一大股东关联人非经营性占用资金的，也应填写本表非经营性占用部分。 | 非经营性资金占用 | 资金占用方名称 | 占用方与上市公 | 上市公司核算 | 2025 年年初占 | 2025 年 1-6 月占 用累计发生金额 | 2025 年 1-6 月 占用资金的利 | 2025年1-6月 偿还累计发 | 2025 年 6 月末 | 占用形成 | 占用性质 | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | | 司的关联关系 | 的会计科目 | 用资金余额 | （不含利息） | 息（如有） | 生金额 | 占用资金余额 | 原因 | | | 控股股东、实际控 | | | | | | | | | | 非经营性占用 | | 制人及其附属企业 | | | | | | | | | | 非经营性占用 | ...

证券代码：300318 证券简称：博晖创新 公告编号：临 2025-031 1、审议通过《<2025 年半年度报告>及其摘要》 监事会认为：公司结合 2025 年半年度的实际经营管理情况编制的《<2025 年 半年度报告>及其摘要》符合《深圳证券交易所创业板股票上市规则》、《上市公司 信息披露管理办法》等法律法规的相关要求。其内容真实、准确、完整的反映了公 司 2025 年半年度的经营管理情况，不存在虚假记载、误导性陈述或重大遗漏。该 报告未经会计师事务所审计。 北京博晖创新生物技术集团股份有限公司 第八届监事会第十二次会议决议公告 本公司及监事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 一、监事会会议召开情况 北京博晖创新生物技术集团股份有限公司（以下简称"公司"或"博晖创新"）第 八届监事会第十二次会议于 2025 年 8 月 27 日在公司会议室召开，会议通知于 2025 年 8 月 15 日以专人送达、邮件通知或电话通知的方式送达各位监事。会议由 公司监事会主席杜江虹女士主持，会议采取现场和通讯表决相结合方式进行，本次 会议应出席监事 3 人，实际出席监事 3 ...

证券代码：300318 证券简称：博晖创新 公告编号：临 2025-030 北京博晖创新生物技术集团股份有限公司 第八届董事会第十三次会议决议公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 一、董事会会议召开情况 北京博晖创新生物技术集团股份有限公司（以下简称"公司"或"博晖创新"） 第八届董事会第十三次会议于 2025 年 8 月 27 日在公司会议室召开，会议通知于 2025 年 8 月 15 日以专人送达、邮件通知或电话通知的方式送达各位董事，会议 由公司董事长沈治卫先生主持，会议采取现场和通讯表决相结合方式进行，本次 会议应出席董事 7 人，实际出席董事 7 人，监事和高级管理人员列席了会议。本 次会议的召集召开程序符合《公司法》和《公司章程》的有关规定。 二、董事会会议审议情况 本次会议审议通过了以下议案： 1、审议通过《<2025 年半年度报告>及其摘要》 同意公司根据《深圳证券交易所创业板股票上市规则》、《公开发行证券的公 司信息披露内容与格式准则第 3 号——半年度报告的内容与格式》等法律法规的 相关要求，结合本公司 2025 年上半年的 ...

Financial Performance - The company's operating revenue for the first half of 2025 was ¥403,960,042.20, a decrease of 17.03% compared to ¥486,888,926.66 in the same period last year[18] - The net profit attributable to shareholders of the listed company was -¥18,688,204.59, representing a decline of 167.63% from ¥27,633,766.56 in the previous year[18] - The net cash flow from operating activities was -¥50,613,850.12, a significant drop of 388.83% compared to ¥17,523,461.09 in the same period last year[18] - The basic earnings per share were -¥0.0229, down 167.75% from ¥0.0338 in the previous year[18] - The company reported a significant increase in cash and cash equivalents, with a net increase of 592.25% to ¥91,804,021.47[58] - The company reported a total comprehensive loss of CNY 30,105,785.85 for the first half of 2025, contrasting with a comprehensive income of CNY 56,026,235.20 in the prior year[169] - The company reported a net loss of CNY 217,971,925.74, compared to a loss of CNY 199,283,721.15 in the previous period[164] Assets and Liabilities - Total assets at the end of the reporting period were ¥4,316,123,512.54, an increase of 4.62% from ¥4,125,558,100.42 at the end of the previous year[18] - The total amount of guarantees at the end of the reporting period was 236,500,000 CNY, with actual guarantee balances totaling 92,958,230 CNY[133] - Total liabilities increased to CNY 1,997,100,759.06 from CNY 1,776,429,561.09, marking a rise of approximately 12.4%[164] - The company's total equity decreased to CNY 1,360,384,587.77 from CNY 1,378,686,990.40, a decline of about 1.3%[164] Revenue Streams - The company’s inspection and testing business achieved a main operating revenue of 99.61 million yuan, a year-on-year decrease of 16.79%[31] - Revenue from in vitro diagnostic products was 47.90 million yuan, down 38.14% compared to the previous year, while non-medical testing products revenue increased by 22.34% to 51.71 million yuan[31] - The company’s biopharmaceutical business achieved main operating revenue of 286.66 million yuan, a year-on-year decrease of 18.33% due to reduced demand for blood products and lower sales volume[45] Research and Development - The company has initiated a strategic partnership with F to enhance its product offerings and market reach[36] - The company is actively involved in the research and development of innovative medical devices to enhance its market position[33] - Research and development investment decreased by 9.87% to ¥35,963,544.34, indicating a focus on cost management[58] - The company is focused on expanding its product line with new technologies and medical devices to enhance diagnostic capabilities[39] Product Development and Registration - The company has a total of 53 medical device registration certificates as of June 30, 2024, with 1 certificate canceled and 2 renewed during the first half of 2024[32] - The company is currently in the registration application phase for several medical devices, including a nucleic acid detection kit for reproductive tract pathogens, which is in the clinical conclusion stage[40] - The company has developed a fluorescence immunoassay analyzer for quantitative detection of substances in human samples, with a registration valid until December 2029[33] Market Strategy - The company has established long-term stable partnerships with multiple distributors across the country, enhancing its market position through innovative technology[29] - The company's strategy includes building a customer network through instrument sales and driving reagent sales via technical services[29] - The company is expanding its market presence with plans to enter D new regions by the end of the fiscal year[36] Financial Management - The company has established a strong quality management system, achieving certifications such as GMP, ISO13485, and ISO9001[53] - The company has maintained a focus on the health industry, emphasizing technological innovation and strategic expansion[50] - The company is seeking a comprehensive financing credit limit of up to RMB 2 billion from banks and financial institutions[141] Shareholder Information - The total number of shares after the recent changes is 816,900,495, with 2.25% being limited shares and 97.75% being unrestricted shares[148] - The largest shareholder, Du Jiangtao, holds 39.03% of the shares, totaling 318,811,388 shares[150] - The total number of shareholders at the end of the reporting period is 31,104[150] Compliance and Regulations - The company adheres to the regulations set by the National Medical Products Administration for its medical devices[33] - The company has not reported any changes in accounting policies or prior period error corrections during this reporting period[191] - The company’s blood products are subject to batch release management, ensuring compliance with regulatory standards before market release[43]

Group 1 - The A-share biopharmaceutical sector experienced a short-term surge, with Tian Tan Biological reaching the daily limit, and Wan Ze Shares previously hitting the limit as well [1] - Other companies such as Aidi Pharmaceutical, Zhifei Biological, Boya Biological, Bohui Innovation, and Pailin Biological also saw increases in their stock prices [1] - The news is driven by the completion of China's first copy-type Tian Tan smallpox vaccine carrier HIV vaccine Phase I clinical trial by teams from the Chinese Center for Disease Control and Prevention and the AIDS Prevention Center [1]

Group 1 - The biopharmaceutical sector experienced a short-term surge, with TianTan Bio reaching the daily limit increase [1] - WanZe Co. previously hit the limit up, indicating strong market interest [1] - Other companies such as Aidi Pharmaceutical, ZhiFei Biological, BoYa Bio, BoHui Innovation, and PaiLin Bio also saw significant gains [1]