Summary of the Conference Call for Xingqi Eye Pharmaceutical Company Overview - **Company**: Xingqi Eye Pharmaceutical - **Industry**: Ophthalmic Pharmaceuticals Key Financial Performance - **2024 Revenue**: 1.943 billion CNY, up 32.42% YoY [2] - **2024 Net Profit**: 338 million CNY, up 40.84% YoY [2] - **Q1 2025 Revenue**: 536 million CNY, up 53.24% YoY [5] - **Q1 2025 Net Profit**: 146 million CNY, up 319.86% YoY [5] - **Proposed Dividend**: 10 CNY per 10 shares and a bonus issue of 4 shares per 10 shares, pending shareholder approval [2][4] Research and Development - **R&D Investment**: 235 million CNY in 2024, accounting for 12.11% of revenue, up 29.55% YoY [6] - **Approved Ophthalmic Drugs**: 60, with 38 included in medical insurance and 6 in the national essential drug list [6][7] - **Clinical Trials**: - 0.01% Atropine eye drops approved; - Voriconazole eye drops completed Phase I; - Cyclosporine eye drops completed Phase IV; - 0.02% and 0.04% Atropine eye drops completed Phase III trials [7][19] Production and Quality Management - **Production Capacity**: Four GMP-certified production lines for 0.01% Atropine eye drops, currently meeting market demand [13] - **Quality Management Initiatives**: Enhanced quality management systems and lean 6S management mechanisms [8] Marketing and Sales Strategy - **Sales Network**: Comprehensive online and offline channels, including partnerships with over 200 chain pharmacies and coverage of more than 12,000 locations [3][14] - **Target for 2025**: Reach over 20 million people aware of the treatment and ensure over 1 million children receive appropriate medication [17][25] - **Atropine Sales Contribution**: Over 10% of the company's main business revenue [13] Market Dynamics and Competition - **Market Potential**: High prevalence of myopia among children in China, with over 50% affected [24] - **Competitor Landscape**: Anticipation of increased competition from other companies like Heng Rui, with a focus on maintaining market share through comprehensive marketing strategies [24] Future Outlook - **2025 Revenue Growth Expectation**: Anticipated double-digit growth, with a focus on operational efficiency and cost management [26] - **Net Profit Margin Target**: Aiming for a net profit margin of 25% to 30% [28] - **Expansion Plans**: Continued investment in R&D and potential entry into overseas markets [30] Strategic Vision - **Long-term Goals**: To become a globally competitive research and manufacturing enterprise in the ophthalmic field, focusing on sustainable growth and innovation [12][34] Additional Insights - **Sales Team Expansion**: Increased sales personnel to 1,100, with a focus on promoting Atropine products [27] - **Sales Expense Management**: Maintaining stable sales expense ratios while driving sales growth [32][33]

Core Viewpoint - Xingqi Eye Pharmaceutical achieved significant growth in both performance and ESG (Environmental, Social, and Governance) metrics in 2024, with a strong start in 2025, driven by product development and market expansion [1][2]. Financial Performance - In 2024, the company reported revenue of 1.943 billion yuan, a year-on-year increase of 32.42%, marking the highest revenue since its listing; net profit reached 338 million yuan, up 40.84% year-on-year, also a record high [2]. - The eye drop segment generated 1.366 billion yuan in revenue in 2024, a remarkable growth of 106.08%, accounting for over 70% of total revenue, primarily due to the rapid sales of low-concentration atropine eye drops [2]. - In Q1 2025, the company achieved revenue of 536 million yuan, a year-on-year increase of 53.24%, and net profit of 146 million yuan, up 319.86% year-on-year, both setting new records since its listing [3]. Product Development and Market Strategy - The company focuses on various eye care products, including those for myopia control and dry eye treatment, with a 2024 R&D investment of 235 million yuan, a 29.55% increase from the previous year [2]. - The low-concentration atropine eye drops, approved in March 2024, are expected to have significant sales potential due to their effectiveness in slowing myopia progression among youth [3]. ESG Performance - Xingqi Eye Pharmaceutical has been recognized for its strong ESG performance, achieving A-level ratings in multiple assessments, reflecting its commitment to environmental protection, social responsibility, and corporate governance [5]. - In 2024, the company reduced its carbon emissions per unit of revenue by 17.77% and increased the proportion of clean energy usage from 6% to approximately 30% [5][6]. - The company invested 15.96 million yuan in public welfare in 2024, a 37.33% increase, and conducted 271 public welfare activities, serving over 208,800 individuals [8]. Future Outlook - For 2025, the company plans to continue increasing R&D investments, focusing on niche areas in ophthalmology and enhancing its product line, particularly in biologics for retinal diseases [4]. - The company aims to strengthen its production management and optimize processes across various dimensions to ensure high-quality development [4].

Performance Overview - In 2024, the company achieved revenue of CNY 1.943 billion, a year-on-year increase of 32.42% [2] - The total profit for 2024 was CNY 395 million, up 49.07% from the previous year [2] - The net profit attributable to shareholders was CNY 338 million, reflecting a growth of 40.84% [3] - In Q1 2025, revenue reached CNY 536 million, a 53.24% increase year-on-year [3] - The total profit for Q1 2025 was CNY 178 million, showing a remarkable growth of 277.02% [3] - The net profit attributable to shareholders in Q1 2025 was CNY 146 million, up 319.86% [3] Dividend Policy - The proposed dividend for 2024 is CNY 10 per 10 shares, with a bonus issue of 4 shares for every 10 shares held [3] Product and Market Strategy - The company focuses on self-research and development, enhancing core competitive advantages, and optimizing customer structure [2] - The product "Meioupin®" (0.01% atropine sulfate eye drops) accounted for over 10% of the company's main business revenue in 2024 [4] - The company has established a comprehensive sales network covering both online and offline channels, enhancing accessibility for consumers [5] - Collaborations with over 200 chain pharmacies and more than 12,000 outlets have been established to meet diverse patient needs [5] Market Potential and Growth - The overall myopia rate among children and adolescents in China is 52.7%, with significant market potential for myopia prevention products [10] - The company aims to raise awareness of the treatment plan to over 20 million people and ensure over 1 million children receive proper medication [10] - The company plans to maintain a double-digit growth rate in 2025, with a focus on optimizing cost control and improving operational efficiency [12] Sales and Distribution Channels - The company has entered over 4,000 public and private medical institutions, with plans for further expansion [11] - The sales strategy includes a full-channel marketing approach, integrating hospitals, pharmacies, and e-commerce platforms [9] - In 2024, offline channels accounted for over 50% of atropine sales [9] Future Outlook - The company anticipates stable growth in net profit margins, projecting a net profit margin of 25%-30% as atropine sales increase [16] - Continuous investment in R&D for innovative ophthalmic drugs is planned to enhance competitive advantage [17] - The company is preparing for potential overseas market expansion, leveraging its differentiated product pipeline [16]

Core Viewpoint - The company, Xingqi Eye Pharmaceutical, reported strong financial performance for 2024, with significant growth in revenue and net profit, driven by product innovation and effective marketing strategies [1][4]. Financial Performance - In 2024, the company achieved operating revenue of 1.943 billion yuan, a year-on-year increase of 32.42% - Net profit reached 338 million yuan, up 40.84% year-on-year - The non-deductible net profit was 348 million yuan, reflecting a growth of 44.54% - Basic earnings per share were 1.94 yuan, with a distribution plan of 4 shares for every 10 shares and a cash dividend of 10 yuan (tax included) [1]. Research and Development - The company has consistently prioritized R&D, with investments of 190 million yuan, 181 million yuan, and 235 million yuan over the past three years, representing 15.22%, 12.38%, and 12.11% of operating revenue respectively - Plans to enhance R&D efforts include expanding the product line in the ophthalmology sector and strengthening the biopharmaceutical layout for retinal diseases [2][3]. - Currently, the company holds 60 approved ophthalmic drug licenses, with 38 products included in the medical insurance directory and 6 in the national essential drug list [2]. Market Strategy - The ophthalmology industry is experiencing growth in market size, technological innovation, and competition, while facing challenges from policy changes - The company emphasizes talent development and has established a comprehensive marketing support system to enhance the professional capabilities of its marketing team [3]. - A customer-centric and academically driven marketing management model has been adopted, supported by a multi-tiered marketing network and partnerships with major distributors across the country [3]. Growth Drivers - Key drivers of the company's profit growth include product innovation and R&D, market expansion and marketing efforts, cost control, and operational efficiency improvements - The company aims to implement a comprehensive development strategy focused on sustainable profit growth, guided by principles of innovation, quality, and shared growth [4].

Group 1: Company Performance - In 2024, the company achieved a revenue of CNY 1.943 billion, representing a year-on-year growth of 32.42% [4] - The total profit reached CNY 395 million, with a year-on-year increase of 49.07% [4] - The compound annual growth rate (CAGR) of revenue over the past three years is 24.70% [4] Group 2: Marketing and Sales Strategy - The company emphasizes building a stable marketing team while attracting external talent to enhance its marketing capabilities [3] - A multi-tiered marketing network has been established, covering all provinces and regions in China [3] - The marketing strategy focuses on academic promotion through meetings and seminars to disseminate product information [3] Group 3: Product Portfolio - The company specializes in ophthalmic drugs, with a product range that includes treatments for myopia, dry eye, infections, and glaucoma [6] - Currently, the company holds 60 approved ophthalmic drug licenses, with 38 products included in the medical insurance directory [6] - Key products contributing over 10% of revenue include Cyclosporine Eye Drops and Atropine Sulfate Eye Drops [6] Group 4: Research and Development - R&D investments over the past three years were CNY 190 million, CNY 181 million, and CNY 235 million, accounting for 15.22%, 12.38%, and 12.11% of revenue respectively [10] - Future R&D plans include expanding the product line in the ophthalmic sector and focusing on biologics for retinal diseases [10] Group 5: ESG Initiatives - The company aims to integrate ESG principles into its strategic planning and operations, focusing on green and low-carbon development [8] - Achievements include being recognized as a "National Green Factory" and implementing measures to reduce energy consumption and waste [9] - The company plans to enhance transparency in ESG reporting and stakeholder communication [8]

国泰海通证券股份有限公司关于沈阳兴齐眼药股份有限公司 向特定对象发行股票并上市之保荐总结报告书 | 保荐机构名称： | 国泰海通证券股份有限公司 | | --- | --- | | 保荐机构编号： | Z29131000 | 经中国证券监督管理委员会《关于同意沈阳兴齐眼药股份有限公司向特定对象 发行股票注册的批复》（证监许可[2021]1343 号）批复，沈阳兴齐眼药股份有限公 司（以下简称"上市公司"、"公司"或"发行人"）向特定对象发行股票 5,763,282 股，每股面值人民币 1 元，每股发行价格人民币 104.05 元/股，募集资金总额为人民 币 599,669,492.10 元，扣除发行费用后，实际募集资金净额为人民币 580,179,086.77 元。本次发行证券已于 2022 年 1 月 18 日在深圳证券交易所创业板上市。原海通证 券股份有限公司担任其持续督导保荐机构，持续督导期间为 2022 年 1 月 18 日至 2024 年 12 月 31 日。鉴于原国泰君安证券股份有限公司换股吸收合并原海通证券股 份有限公司事项已获得中国证券监督管理委员会核准批复，本次合并交易已于 2025 年 3 ...

2024 年度持续督导跟踪报告 国泰海通证券股份有限公司 关于沈阳兴齐眼药股份有限公司 | 保荐人名称：国泰海通证券股份有限公司 | 被保荐公司简称：兴齐眼药 | | --- | --- | | 保荐代表人姓名：石迪 | 联系电话：021-23187088 | | 保荐代表人姓名：王显 | 联系电话：021-23185968 | 三、公司及股东承诺事项履行情况 | 公司及股东承诺事项 | 是否履行承诺 | 未履行承诺的原因及 | | --- | --- | --- | | | | 解决措施 | | 1.关于同业竞争、关联交易、资金占 | 是 | 不适用 | | 用方面的承诺 | | | | 2.关于股份限售的承诺 | 是 | 不适用 | | 3.关于公司本次发行摊薄即期回报采 | 是 | 不适用 | | 取填补措施的承诺 | | | | 4. 关于股权激励的承诺 | 是 | 不适用 | 四、其他事项 一、保荐工作概述 | 项目 | 工作内容 | | --- | --- | | 1.公司信息披露审阅情况 | | | （1）是否及时审阅公司信息披露文件 | 是 | | （2）未及时审阅公司信息披露文件的次数 | ...

国泰海通证券股份有限公司 关于沈阳兴齐眼药股份有限公司 2024 年度持续督导工作现场检查报告 | 保荐人名称：国泰海通证券股份有限公司 被保荐公司简称：兴齐眼药 | | --- | | （以下简称"国泰海通"或"保荐人"） | | 保荐代表人姓名：石迪 联系电话：021-23187088 | | 保荐代表人姓名：王显 联系电话：021-23185968 | | 现场检查人员姓名：石迪 | | 现场检查对应期间：2024 年度 | | 现场检查时间：2025 年 月 日 4 18 | | 一、现场检查事项 现场检查意见 | | （一）公司治理 是 否 不适用 | | 现场检查手段：查阅了上市公司最新章程、三会议事规则及会议材料，取得上市公司董 | | 事、监事、高级管理人员名单及其变化情况，取得上市公司关联方清单，查阅关于公司控 | | 股股东、实际控制人、董事、监事、高级管理人员的信息披露文件，查看上市公司生产经 | | 营场所，对上市公司高级管理人员进行访谈。 | | 1.公司章程和公司治理制度是否完备、合规 √ | | 2.公司章程和股东大会、董事会、监事会规则是否得到有效执行 √ | | 3.股东大会 ...

Core Viewpoint - In 2024, Xingqi Eye Medicine (300573.SZ) demonstrated strong growth in the ophthalmic prescription drug sector, achieving significant revenue and profit increases, solidifying its leading position in the industry [1][2]. Financial Performance - The company reported a total revenue of 1.943 billion yuan in 2024, representing a year-on-year increase of 32.42% [2]. - Net profit reached 338 million yuan, up 40.84% year-on-year, with a non-recurring net profit growth of 44.54% to 348 million yuan [2]. - The net cash flow from operating activities was 417 million yuan, reflecting a 31.31% increase [2]. Product Performance - The eye drop segment showed remarkable growth, generating 1.366 billion yuan in revenue, a 106.08% increase, and accounting for 70.3% of total revenue [2]. - Key products driving this growth included low-concentration atropine eye drops (brand name "Mei Ou Pin") and cyclosporine eye drops (II) [2]. Investor Returns - The company proposed a profit distribution plan, intending to distribute a cash dividend of 10 yuan per 10 shares, totaling 175 million yuan, and a capital reserve conversion of 4 shares for every 10 shares held [3]. Production and Quality Management - The company focused on enhancing production and quality management, optimizing resource allocation, and upgrading production facilities to improve efficiency and support smart factory initiatives [4]. - Quality management improvements included passing various regulatory inspections and certifications, indicating a stable and effective quality management system [5]. Research and Development - In 2024, R&D expenses reached 221 million yuan, a 31.90% increase, with the company holding 66 invention patents [6]. - Significant progress was made in R&D, including the approval of clinical trials for new products aimed at treating common eye diseases [6][7]. Future Outlook - For 2025, the company reported a revenue of 536 million yuan in Q1, a 53.24% increase, and a net profit of 146 million yuan, up 319.86% year-on-year [8]. - The company outlined four key operational plans for 2025: production and quality centers, product R&D, marketing, and internal control management, with a focus on unmet clinical needs and innovation [9].

Core Viewpoint - Shenyang Xingqi Eye Pharmaceutical Co., Ltd. reported significant growth in revenue and net profit for the fiscal year 2024, driven by the exclusive market position of atropine eye drops, although rising sales and R&D expenses have raised concerns [2][3]. Financial Performance - The company achieved a revenue of 1.943 billion yuan in 2024, representing a year-on-year increase of 32.42%, while the net profit excluding non-recurring items reached 348 million yuan, up 44.54% from the previous year [2]. - The revenue from the eye drop segment was 1.366 billion yuan, accounting for 70.3% of total revenue, with a gross margin of 82.18% [3]. Product Development - The atropine eye drops, which received a drug registration certificate in March 2024, are aimed at slowing the progression of myopia in children aged 6 to 12 years [3][4]. - The company currently holds 60 approved ophthalmic drug registrations, with 38 products included in the medical insurance catalog and 6 in the national essential drug list [2]. Expense Analysis - Sales expenses have increased significantly, being three times the R&D expenses, with sales expenses rising from 463 million yuan in 2022 to 705 million yuan in 2024, while R&D expenses grew from 146 million yuan to 221 million yuan during the same period [5]. - Financial expenses also saw a notable increase of 115.66% year-on-year, attributed to rising bank loan interest [5]. Market Competition - The exclusive market position of atropine eye drops may soon be challenged as several listed companies, including Zhaoke Ophthalmology and Hengrui Medicine, are advancing their own products in this category [4].