| 指标 | 开立医疗 | 医疗器械行业均值 | 行业排名 | | --- | --- | --- | --- | | 总市值 | 144.92亿元 | 117.95亿元 | 21 123 | | 净资产 | 31.16亿元 | 38.89亿元 | 47 123 | | 净利润 | 4703.03万元 | 1.49亿元 | 60 123 | | 市盈率(动) | 154.07 | 66.45 | 81 123 | | 市净率 | 4.65 | 3.78 | 96 123 | | 毛利率 | 62.08% | 51.85% | 50 123 | | 净利率 | 4.88% | 10.39% | 84 123 | | ROE | 1.5% | 1.8% | 75 123 | 证券之星消息，截至2025年10月14日收盘，开立医疗(300633)报收于33.49元，下跌1.82%，换手率 0.84%，成交量3.65万手，成交额1.23亿元。 10月14日的资金流向数据方面，主力资金净流出236.31万元，占总成交额1.91%，游资资金净流入 294.81万元，占总成交额2.39%，散户资金净流出58.49万元，占总 ...

Investment Rating - The report maintains a "Market Weight" rating for the pharmaceutical and biotechnology industry [2][24]. Core Viewpoints - The SW pharmaceutical and biotechnology industry underperformed the Shanghai and Shenzhen 300 index, declining by 0.23% from September 26, 2025, to October 9, 2025, lagging behind the index by approximately 2.76 percentage points [9][24]. - Most sub-sectors within the industry recorded negative returns during the same period, with the medical research outsourcing and in vitro diagnostics sectors showing gains of 1.99% and 0.55%, respectively, while the raw materials and chemical preparations sectors fell by 2.23% and 1.73% [10][24]. - Approximately 54% of stocks in the industry achieved positive returns, with the top performer, Zhendemedical, increasing by 21.43%, while the largest decline was seen in Guangshentang, which fell by 21.86% [11][14]. - The overall price-to-earnings (PE) ratio for the SW pharmaceutical and biotechnology industry was approximately 55.04 times as of October 9, 2025, indicating a decrease in industry valuation [15][24]. Summary by Sections 1. Market Review - The SW pharmaceutical and biotechnology industry underperformed the Shanghai and Shenzhen 300 index, with a decline of 0.23% from September 26, 2025, to October 9, 2025 [9]. - Most sub-sectors recorded negative returns, with medical research outsourcing and in vitro diagnostics performing better than others [10]. - About 54% of stocks in the industry recorded positive returns, with significant variations in individual stock performance [11]. 2. Industry News - The 11th batch of national procurement will begin accepting applications on October 21, 2025, with 55 major varieties included [22]. - The National Medical Products Administration issued guidelines for the quality management of medical device online sales [20][21]. 3. Company Announcements - Zhejiang Haizheng Pharmaceutical announced that its product achieved Self-GRAS certification in the U.S., allowing it to enter the U.S. market [23]. 4. Weekly Industry Perspective - The report suggests focusing on investment opportunities in innovative drugs and sectors with expected business development catalysts, including medical devices and pharmaceutical commerce [24][26].

Core Viewpoint - KAILI Medical's stock price has shown fluctuations, with a year-to-date increase of 15.02%, but a recent decline of 3.49% over the last five trading days, indicating potential volatility in the market [1] Financial Performance - For the first half of 2025, KAILI Medical reported a revenue of 964 million yuan, a year-on-year decrease of 4.78%, and a net profit attributable to shareholders of 47.03 million yuan, down 72.43% compared to the previous year [2] - Cumulative cash dividends since the A-share listing amount to 381 million yuan, with 258 million yuan distributed over the last three years [3] Shareholder Structure - As of June 30, 2025, the number of shareholders decreased by 1.46% to 14,300, while the average circulating shares per person increased by 1.48% to 30,244 shares [2] - Notable institutional shareholders include Huabao Zhongzheng Medical ETF and Guangfa Medical Health Stock A, with both increasing their holdings [3] Company Overview - KAILI Medical, established on September 27, 2002, and listed on April 6, 2017, specializes in the research, development, production, and sales of medical diagnostic and treatment equipment [1] - The company's main revenue sources are color ultrasound (58.07%) and endoscopes and related therapeutic instruments (40.90%) [1] Market Position - KAILI Medical operates within the pharmaceutical and biological industry, specifically in the medical device sector, and is involved in various concept sectors including medical devices and in vitro diagnostics [1]

Core Viewpoint - The company reported a decline in revenue and net profit for the first half of 2025, with a significant drop in net profit attributed to high fixed costs and ongoing investments in new product lines [1][3]. Revenue Analysis - In H1 2025, the company's operating revenue was 964 million yuan, a decrease of 4.78% year-on-year, while the net profit attributable to shareholders was 47 million yuan, down 72.43% [1]. - Domestic revenue saw a year-on-year decline of 9.17%, despite a recovery in the medical equipment sector and increased bidding amounts for ultrasound and endoscope products [2]. - The overseas revenue growth was stable, with a year-on-year increase of 0.33% in H1 2025, primarily due to a high base in H1 2024 [2]. - In Q2 2025, the operating revenue was 534 million yuan, showing a slight increase of 0.17% compared to the previous quarter [1][2]. Profit Analysis - The net profit for H1 2025 experienced a significant decline of 72.43%, which was more severe than the revenue decline, mainly due to substantial fixed costs related to new product lines and R&D expenses [3]. - In Q2 2025, the net profit attributable to shareholders was 39 million yuan, reflecting a year-on-year decrease of 44.65%, but an improvement from Q1's decline of 91.94% [3]. - The company has maintained a R&D expense ratio of around 20%, indicating a commitment to continuous investment in product development [3]. Product Development - The company launched the iEndo series 4K smart endoscope platform in 2025, featuring ultra-high-resolution imaging capabilities [3]. - New products in the minimally invasive surgery sector, such as the SV-M4K200 platform, were also introduced, enhancing surgical precision and efficiency [3]. Investment Outlook - The company forecasts net profits of 300 million yuan, 410 million yuan, and 540 million yuan for 2025 to 2027, with corresponding price-to-earnings ratios of 49, 36, and 27 [4]. - A DCF model estimates the company's overall valuation at 20 billion yuan, with a target price of approximately 46 yuan, maintaining a "recommended" rating [4].

Investment Rating - The report maintains a "Recommended" rating for the company with a target price of 46 yuan [2][6]. Core Views - The company's performance is improving gradually, with new business lines experiencing rapid growth. The revenue for H1 2025 was 964 million yuan, a decrease of 4.78% year-on-year, while the net profit attributable to shareholders was 47 million yuan, down 72.43% [2][6]. - The report highlights that the domestic business is under pressure, but overseas revenue remains stable. The company’s existing business lines, such as ultrasound and endoscopy, continue to grow steadily, providing ongoing profit and cash flow [2][6]. - The company is investing heavily in R&D, maintaining a research expense ratio around 20%, and has launched new products in the endoscopy and minimally invasive surgery sectors [2][6]. Financial Summary - For 2025, the company is projected to have total revenue of 2,387 million yuan, with a year-on-year growth rate of 18.5%. The net profit attributable to shareholders is expected to reach 303 million yuan, reflecting a growth rate of 113% [2][7]. - The earnings per share (EPS) for 2025 is estimated at 0.70 yuan, with a price-to-earnings (P/E) ratio of 49 times [2][7]. - The company’s total assets are projected to grow from 4,313 million yuan in 2024 to 5,736 million yuan by 2027, indicating a strong growth trajectory [7].

Group 1 - A total of 36 stocks received buy ratings from institutions today, with 20 stocks being newly covered by institutions [1][2] - The medical and pharmaceutical industry is the most favored, with stocks like Kaili Medical and Tianshili among the top-rated [2][3] - The average decline for stocks with buy ratings today was 0.32%, underperforming the Shanghai Composite Index [1] Group 2 - Among the stocks with buy ratings, Dongyangguang has the highest upside potential at 45.56%, with a target price of 35.88 yuan [1][2] - Other stocks with significant upside potential include Shenling Environment and Luxshare Precision, with upside potentials of 35.04% and 32.12% respectively [1] - The stocks with the largest gains today included Zhongwei Company, Luxshare Precision, and Tianshili, with increases of 9.12%, 7.79%, and 3.06% respectively [1]

证券代码：300633 证券简称：开立医疗 公告编号：2025-039 深圳开立生物医疗科技股份有限公司 关于 2025 年限制性股票与股票期权激励计划内幕信息知情人及 激励对象买卖公司股票情况的自查报告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 深圳开立生物医疗科技股份有限公司（以下简称"公司"）于 2025 年 9 月 4 日召开第四届董事会第十次会议、第四届监事会第九次会议，审议通过了《关 于公司 2025 年限制性股票与股票期权激励计划（草案）及其摘要的议案》等相 关议案，并于 2025 年 9 月 6 日在巨潮资讯网（http://www.cninfo.com.cn）上披 露相关公告。 根据《上市公司股权激励管理办法》（以下简称"《管理办法》"）、《深圳证 券交易所创业板上市公司自律监管指南第 1 号——业务办理》（以下简称"《自 律监管指南》"）等相关法律、法规的规定，通过向中国证券登记结算有限公司 深圳分公司查询，公司对 2025 年限制性股票与股票期权激励计划（以下简称"本 次激励计划"）内幕信息知情人及激励对象在本次激励计划草案公告前 ...

证券代码：300633 证券简称：开立医疗 公告编号：2025-040 深圳开立生物医疗科技股份有限公司 2025 年第一次临时股东大会决议公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏 特别提示： 1、本次股东大会未出现否决议案的情形； 2、本次股东大会未涉及变更以往股东大会已通过的决议。 （2）网络投票：通过深圳证券交易所交易系统进行网络投票的时间为 2025 年 9 月 23 日上午 9:15-9:25，9:30-11:30，下午 13:00-15:00；通过深圳证券交易 所互联网系统投票的具体时间为 2025 年 9 月 23 日 9:15-15:00 期间的任意时间。 2、现场会议召开地点：深圳市光明区光电北路 368 号开立医疗大厦一楼 121 会议室 3、召开方式：现场表决与网络投票相结合的方式 4、召集人：深圳开立生物医疗科技股份有限公司董事会 5、主持人：董事长陈志强先生 6、会议的召开符合相关法律、行政法规、部门规章、规范性文件和公司章 程的规定。 （二）出席情况 一、会议的召开和出席情况 （一）召开情况 1、召开时间： （1）现场会议 ...

北京市中伦（深圳）律师事务所 关于深圳开立生物医疗科技股份有限公司 2025年第一次临时股东大会的 法律意见书 二〇二五年九月 北京市中伦（深圳）律师事务所 关于深圳开立生物医疗科技股份有限公司 2025 年第一次临时股东大会的 法律意见书 致：深圳开立生物医疗科技股份有限公司 上述公告载明了召开本次股东大会的时间、地点、议案、会议召开方式、会 议出席对象、会议登记事项等。公司已按照有关规定对议案内容进行了披露。 根据《中华人民共和国公司法》（以下简称"《公司法》"）、《上市公司股东 会规则》（以下简称"《股东会规则》"）和《深圳开立生物医疗科技股份有限公 司章程》（以下简称"《公司章程》"）的规定，北京市中伦（深圳）律师事务所 （以下简称"本所"）接受深圳开立生物医疗科技股份有限公司（以下简称"公司"） 的委托，指派律师出席公司 2025 年第一次临时股东大会（以下简称"本次股东大 会"），并就本次股东大会的召集和召开程序、出席和列席会议人员资格、表决程 序及表决结果等事宜发表法律意见。 本所律师根据《股东会规则》的要求，按照律师行业公认的业务标准、道德 规范和勤勉尽责的精神，参加了本次股东大会现场会议，并 ...

Core Viewpoint - The report from Zhongyou Securities indicates that Kaili Medical's net profit attributable to the parent company for H1 2025 is 47 million yuan, a year-on-year decrease of 72.43% [1] - The net profit attributable to the parent company after deducting non-recurring gains and losses is 40 million yuan, a year-on-year decrease of 74.26% [1] - Despite the decline in profits, the domestic medical device industry is showing signs of recovery, with significant growth in the bidding success of ultrasound and endoscope products [1] Industry Summary - The domestic medical device industry is experiencing a revival in terminal bidding, which is expected to positively impact company performance as market demand continues to improve [1] - The past two years of industry restructuring have created a lag between market bidding and revenue growth reported by companies [1] Company Summary - Kaili Medical is actively building its marketing network both domestically and internationally, with a focus on local construction, product innovation, and channel network integration [1] - The company currently has a presence in nearly 170 countries and regions globally [1] - Domestically, the company maintains a clinical value-oriented approach, enhancing regional service capabilities, channel network advantages, and clinical collaborative innovation to support sustained business growth [1] - The company has been given an "Accumulate" rating based on its potential for recovery and growth [1]