广东泰恩康医药股份有限公司 关于控股股东、实际控制人部分股份质押的公告 证券代码：301263 证券简称：泰恩康 公告编号：2025-012 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 广东泰恩康医药股份有限公司（以下简称"公司"）于近日收到公司控股股 东、实际控制人郑汉杰先生、孙伟文女士的通知，获悉其所持有的公司部分股份 办理了质押手续，具体情况如下： | | 是否为 控股股 | | 占其所 | 占公司 | 是否为 限售股 | 是否 | | | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 股东 | 东或第 一大股 | 本次质押 数量 | 持股份 | 总股本 | （如 | 为补 | 质押 | 质押到 | 质权人 | 质押 | | 名称 | | | 比例 | 比例 | 是，注 | 充质 | 起始日 | 期日 | | 用途 | | | 东及其 一致行 | （股） | （%） | （%） | 明限售 | 押 | | | | | | | 动人 | | | | 类 ...

证券代码：301263 证券简称：泰恩康 公告编号：2025-010 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假 记载、误导性陈述或者重大遗漏。 广东泰恩康医药股份有限公司（以下简称"公司"）子公司山东华铂凯盛 生物科技有限公司于近日收到国家药品监督管理局（以下简称"国家药监局"） 签发的聚多卡醇注射液境内生产药品注册上市许可申请《受理通知书》，国家 药监局根据《中华人民共和国行政许可法》第三十二条的规定，对上述药品的 药品注册上市许可申请进行了审查，决定予以受理。现将相关情况公告如下： 一、申请注册药品的基本情况 广东泰恩康医药股份有限公司 关于全资子公司收到药品注册受理通知书的公告 受理号：CYHS2501436 药品名称：聚多卡醇注射液 申请事项：境内生产药品注册上市许可 具有微创、恢复快的优势，未来市场潜力显著。 许可药品注册分类：化学药品 4 类 规格：2ml：20mg 申请人：山东华铂凯盛生物科技有限公司 审核结论：根据《中华人民共和国行政许可法》第三十二条的规定，经审 查，决定予以受理。 二、药品相关情况简介 聚多卡醇又名聚桂醇，聚多卡醇是一种非离子型表面活性剂，通过破坏血 ...

证券代码：301263 证券简称：泰恩康 公告编号：2025-011 广东泰恩康医药股份有限公司 关于全资孙公司增资扩股引入外部投资者的进展公告 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假 记载、误导性陈述或者重大遗漏。 一、交易概述 根据广东泰恩康医药股份有限公司（以下简称"公司"）的战略规划和经营 发展需要，为了加快推进生物制药业务板块的研发进程，公司全资孙公司安徽泰 恩康生物工程有限公司（以下简称"泰恩康生物"）通过增资扩股的方式引入外 部投资者广州赛富生物医药投资合伙企业（有限合伙）（以下简称"赛富生物"） 及宁波海厚泰仁创业投资合伙企业（有限合伙）（以下简称"海厚泰仁"），赛 富生物及海厚泰仁分别以人民币 2,750.0000 万元的价格认购泰恩康生物新增注 册资本人民币 950.2488 万元，增资价款中超出注册资本的部分计入资本公积。 泰恩康生物股东安徽泰恩康制药有限公司（以下简称"安徽泰恩康"，系公司全 资子公司）同意接受本次增资，并相应放弃对本次增资所享有的优先认购权。 本次增资完成后，泰恩康生物注册资本将由 2,000.00 万元增加至 3,980.0996 万元，公司 ...

Investment Rating - The report assigns an "Accumulate" rating for the company, with a target price of 21.06 CNY based on a 54 times P/E ratio for 2025 [3][6]. Core Views - The company is expected to experience rapid progress in its core business or key products over the next 1-2 years, with projected earnings per share of 0.26, 0.39, and 0.62 CNY for 2024-2026 [3]. - The company has a solid foundation as a comprehensive pharmaceutical enterprise, having established a research and development platform and acquired a pipeline of high-potential products [10][15]. - The treatment for vitiligo is scarce, and the company's CKBA product is anticipated to stand out in the market due to its unique mechanism and promising clinical trial results [10][50]. Financial Summary - The company's revenue for 2022 was 783 million CNY, with a projected decline to 757 million CNY in 2024, followed by a recovery to 951 million CNY in 2025 and 1,214 million CNY in 2026, reflecting a growth rate of 25.7% and 27.6% respectively [5]. - The net profit attributable to the parent company is expected to decrease from 175 million CNY in 2022 to 111 million CNY in 2024, before increasing to 165 million CNY in 2025 and 262 million CNY in 2026 [5]. - The gross margin is projected to improve from 58.2% in 2022 to 69.7% in 2026, indicating a positive trend in profitability [5]. Business Overview - The company started as an agent for gastrointestinal and ophthalmic medications and has gradually expanded into various fields, establishing a robust R&D platform since 2015 [10][15]. - The core business segments include gastrointestinal medications, sexual health products, and ophthalmic drugs, with stable growth in revenue from these areas [10][23]. - The company has significantly increased its R&D investment, leading to the development of important products such as dapoxetine and a rich pipeline of innovative drugs [32]. Market Opportunity - The prevalence of vitiligo is high, with over 12.33 million patients in China, and the demand for effective treatments is unmet, creating a significant market opportunity for CKBA [10][37]. - The competitive landscape for vitiligo treatments is favorable, with CKBA being the only non-JAK inhibitor drug in the domestic pipeline, currently in Phase II clinical trials [50][51].

Investment Rating - The report gives the company an "Accumulate" rating for the first time, with a target price of 21.06 CNY based on a 54 times P/E ratio for 2025 [3][6]. Core Views - The company is expected to experience rapid progress in its core business or important products over the next 1-2 years, with projected earnings per share of 0.26, 0.39, and 0.62 CNY for 2024-2026 [3]. - The company has a solid foundation as a comprehensive pharmaceutical enterprise, having established a research and development platform and acquired a pipeline of high-potential products [10][15]. - The treatment for vitiligo is scarce, and the company's CKBA product is expected to stand out in the market due to its unique mechanism and promising clinical trial results [10][50]. Financial Information - The company's revenue for 2022 was 783 million CNY, with a projected revenue of 757 million CNY for 2024, followed by 951 million CNY in 2025 and 1,214 million CNY in 2026, reflecting a growth rate of 25.7% and 27.6% respectively [5]. - The net profit attributable to the parent company for 2022 was 175 million CNY, with projections of 111 million CNY for 2024, 165 million CNY for 2025, and 262 million CNY for 2026, indicating a significant growth trajectory [5]. - The gross margin is expected to improve from 58.6% in 2024 to 69.7% in 2026, while the net margin is projected to increase from 14.7% in 2024 to 21.6% in 2026 [5]. Business Overview - The company started as an agent and has developed into a comprehensive pharmaceutical enterprise, focusing on gastrointestinal, sexual health, and ophthalmic medications [10][15]. - The core products include "Hewei Zhengchang Wan" and "Woli Ting," with a strong emphasis on research and development to enhance product offerings [10][15]. - The company has significantly increased its R&D investment, leading to the successful development of key products like Dapoxetine and a rich pipeline of innovative drugs [32][34].

Group 1 - The company, established in 1999 and listed on the Growth Enterprise Market in 2022, has developed a comprehensive pharmaceutical business starting from agency operations and has built a strong R&D platform through self-construction and acquisitions [1] - The main business segments include gastrointestinal, sexual health, and ophthalmic medications, with overall revenue and profit growth slowing, but core business continuing to grow [1] - Significant increases in R&D investment have been noted, leading to the development of key products such as Dapoxetine Hydrochloride Tablets, along with a rich pipeline of potential products [1] Group 2 - The treatment for vitiligo is scarce, with a high prevalence and strong patient treatment willingness, as evidenced by 12.33 million patients in China in 2021 [2] - The main treatment options currently available include hormones and topical calcineurin inhibitors, but there is a significant unmet clinical need as no new drugs have been approved domestically [2] - CKBA is the only non-JAK inhibitor drug in development for vitiligo, with promising results from its Phase II clinical trials and plans to expand into other indications such as psoriasis and atopic dermatitis [2] Group 3 - The core business includes gastrointestinal medications, with the company planning to shift to self-production to overcome limitations and achieve rapid growth [3] - In the sexual health segment, Dapoxetine Hydrochloride Tablets have become a leading brand, with additional products in development that are expected to drive growth [3] - The ophthalmic segment shows stable sales with growth potential, particularly with the upcoming application for a new drug for presbyopia, which could be the first approved in the domestic market [3] - The company forecasts earnings per share of 0.26, 0.39, and 0.62 yuan for 2024-2026, respectively, and sets a target price of 21.06 yuan based on a 54 times P/E ratio for 2025 [3]

证券代码：301263 证券简称：泰恩康 公告编号：2025-009 广东泰恩康医药股份有限公司 一、交易概述 根据广东泰恩康医药股份有限公司（以下简称"公司"）的战略规划和经营 发展需要，为了加快推进生物制药业务板块的研发进程，公司全资孙公司安徽泰 恩康生物工程有限公司（以下简称"泰恩康生物"）拟通过增资扩股的方式引入 外部投资者广州赛富生物医药投资合伙企业（有限合伙）（以下简称"赛富生物"） 及宁波海厚泰仁创业投资合伙企业（有限合伙）（以下简称"海厚泰仁"），赛 富生物及海厚泰仁分别以人民币 2,750.0000 万元的价格认购泰恩康生物新增注 册资本人民币 950.2488 万元，增资价款中超出注册资本的部分计入资本公积。 同时，向泰恩康生物的核心人员刘冬连先生实施股权激励，刘冬连先生拟以人民 币 79.6020 万元的价格认购泰恩康生物新增注册资本人民币 79.6020 万元。泰恩 康生物股东安徽泰恩康制药有限公司（以下简称"安徽泰恩康"，系公司全资子 公司）同意接受本次增资，并相应放弃对本次增资所享有的优先认购权。 本次增资完成后，泰恩康生物注册资本将由 2,000.00 万元增加至 3,980.0 ...

证券代码：301263 证券简称：泰恩康 公告编号：2025-008 广东泰恩康医药股份有限公司 关于首次公开发行前已发行股份上市流通的 提示性公告 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假 记载、误导性陈述或者重大遗漏。 特别提示： 一、首次公开发行前已发行股份概况 经中国证券监督管理委员会（以下简称"中国证监会"）《关于同意广东泰 恩康医药股份有限公司首次公开发行股票注册的批复》（证监许可〔2022〕203 号）核准，公司首次公开发行人民币普通股（A 股）5,910.00 万股，并于 2022 年 3 月 29 日在深圳证券交易所创业板上市交易。 首次公开发行前，公司总股本为 177,287,500 股；首次公开发行股票完成后， 公司总股本为 236,387,500 股，其中无限售条件流通股为 50,875,193 股，占发行 后总股本的 21.5219%；有限售条件流通股为 185,512,307 股，占发行后总股本的 78.4781%。 2022 年 9 月 29 日，公司首次公开发行网下配售限售股上市流通，股份数量 为 2,789,785 股，占公司总股本的 1.1802%。具 ...

国泰君安证券股份有限公司 关于广东泰恩康医药股份有限公司 首次公开发行前已发行股份上市流通的核查意见 国泰君安证券股份有限公司（以下简称"国泰君安"或"保荐机构"）作为广东 泰恩康医药股份有限公司（以下简称"泰恩康"或"公司"）首次公开发行股票并在 创业板上市的保荐机构及持续督导机构，根据《证券发行上市保荐业务管理办法》 《深圳证券交易所创业板股票上市规则》《深圳证券交易所上市公司自律监管指 引第 2 号——创业板上市公司规范运作》《深圳证券交易所上市公司自律监管指 引第 13 号——保荐业务》等有关法律法规和规范性文件的要求，对泰恩康首次 公开发行前已发行股份上市流通事项进行了核查，具体情况如下： 一、首次公开发行前已发行股份概况 1 公司于 2023 年 5 月 29 日实施完毕 2022 年年度权益分派，其中以资本公积 金向全体股东每 10 股转增 8 股，所转股于 2023 年 5 月 29 日计入股东证券账户， 限售股股东持股数量相应增加，持股比例不变。 2023 年 6 月 29 日，公司部分首次公开发行前已发行股份上市流通，股份数 量为 39,397,500 股，占公司总股本的 9.2592%。 ...

近年来，公司多个药物项目取得关键进展，除本次获受理的"和胃整肠丸"外，此前还有地夸磷索钠滴眼 液境内生产药品注册上市许可获受理、利多卡因丙胺卡因气雾剂完成首例受试者入组、富马酸卢帕他定 片获药品注册证书、注射用紫杉醇聚合物胶束临床试验申请获批等。 泰恩康日前发布公告，全资子公司安徽泰恩康制药有限公司于近日收到国家药监局签发的和胃整肠丸境 内生产药品注册上市许可申请《受理通知书》，国家药监局对上述药品的药品注册上市许可申请进行了 审查，决定予以受理。 公司在公告中表示，"和胃整肠丸" 是一种治疗肠胃疾病的中成药，主要作用为温中和胃、理气止痛， 能够迅速调理肠胃，缓解腹痛腹泻症状，安全性和疗效显著，在我国尤其是东南沿海地区享有较高知名 度。 公司于 2023 年 7 月取得"和胃整肠丸"的全套生产技术及国内的所有权益，此次境内生产药品注册上市 许可获受理，标志着"和胃整肠丸"的国产化进程取得关键进展。"和胃整肠丸"取得国内注册批件后，将 从代理转为自产，解决目前因泰国授权厂商产能限制导致的缺货情况，并进一步提升该品种的毛利率及 盈利能力。 根据权威研究和市场数据，功能性胃肠病已成为全球性健康问题。《胃肠病学》杂志 ...