●施芳 第三级预防，指针对已确诊阿尔茨海默病的患者，预防疾病的进一步发展，包括对症治疗、康复治疗、 日常照护等。家属应为患者提供日常生活起居护理、饮食护理、安全护理等，确保照护环境的安全，降 低患者跌倒和受伤的可能性，避免出现走失等情况。 据《人民日报》 退休后生活节奏骤变，如何预防阿尔茨海默病？早期有什么症状？笔者采访了首都医科大学宣武医院常 务副院长、神经内科主任医师唐毅。 "针对阿尔茨海默病，建议公众开展'三级预防'。"唐毅表示，第一级预防，是在未患病人群中倡导健康 的生活方式，如戒烟限酒、坚持体育锻炼、积极参与社交活动；均衡膳食、控制体重、保持充足睡眠； 勤于阅读、思考，保持大脑活跃。同时控制高血压、糖尿病、血脂异常等慢性病，积极治疗心脑血管疾 病、听力受损、视觉障碍等疾病，保护头部，避免脑损伤。 第二级预防，又称"三早预防"，即早发现、早诊断、早治疗。研究表明，阿尔茨海默病的病理生理改 变，如β—淀粉样蛋白在脑内的沉积，在出现临床症状的15—20年前就已经开始产生，50岁以上的人群 建议进行脑认知健康筛查。如果出现疑似阿尔茨海默病的相关症状，应及时前往医院的记忆门诊就诊。 轻度认知障碍阶段是阿尔茨海 ...

Core Viewpoint - The article highlights the rising trend of pregabalin abuse in China, particularly among youth, as a substitute for previously abused substances like dextromethorphan, raising concerns about its potential for addiction and the need for monitoring [1][2][10]. Group 1: Case Reports and Trends - Recent reports indicate a significant increase in cases of pregabalin abuse, with a notable rise in patients seeking treatment for dependency [1][2][18]. - A case study published in March 2025 documented the first reported instance of pregabalin dependency in China, where a patient escalated their dosage from 16-32 capsules daily to 80 capsules within a month [18]. - The Shandong Drug Adverse Reaction Monitoring Center reported a minor patient who switched to pregabalin after dextromethorphan was regulated, with doses reaching up to 30 capsules per use [2][18]. Group 2: Mechanism and Effects - Pregabalin is primarily used to treat neuropathic pain and anxiety disorders, but its mechanism of action, which lowers neuronal excitability, is being misused for anxiety relief and emotional escape [9][10]. - Users report initial euphoric effects, but prolonged use leads to negative side effects, including paranoia and cognitive decline, as seen in the experiences of individuals like Wang Long [8][9]. Group 3: Accessibility and Regulation - Pregabalin is easily accessible online, often without the need for a legitimate prescription, making it a popular choice among those seeking to abuse substances [16][25]. - The article discusses the potential need for stricter regulations on pregabalin, similar to those imposed on dextromethorphan, due to the increasing number of abuse cases [17][22]. Group 4: Social Dynamics and Influence - Social media and peer influence play significant roles in the spread of drug abuse, with users sharing experiences and recommendations that encourage others to try pregabalin [10][14]. - The normalization of drug use within certain social circles contributes to the ongoing cycle of addiction, as individuals seek to escape negative emotions and social pressures [26][27]. Group 5: Treatment and Prevention Challenges - The article emphasizes the challenges in addressing drug abuse, noting that many individuals do not seek help until their addiction has severely impacted their lives [26][28]. - There is a call for a multi-tiered prevention approach that includes education for at-risk populations, early intervention for those exhibiting risky behaviors, and comprehensive treatment for those already dependent [27].

Core Insights - The article highlights the challenges faced by diabetes patients in managing their condition, emphasizing the need for detailed and personalized management plans to improve patient outcomes [1][2][3] Group 1: Patient Management Challenges - Many diabetes patients struggle with long-term management due to a lack of symptoms, leading to medication non-compliance and poor lifestyle choices [1][2] - Emotional factors such as anxiety and depression can complicate diabetes management, affecting blood sugar control [9][11] Group 2: Medical Approaches - A modern Chinese medicine approach to diabetes management includes a classification system that differentiates between types of diabetes and stages of the disease, allowing for tailored treatment [3][5] - The integration of Western and traditional Chinese medicine is becoming more common, with clinical studies exploring combined treatment methods [5][7] Group 3: Importance of Education and Support - There is a critical need for health education in community and family settings to help patients understand dietary adjustments and medication management [4][10] - Family support plays a significant role in diabetes management, with the need for a balanced approach to avoid over-restriction or neglect of the patient's needs [10][11] Group 4: Prevention of Complications - Diabetes patients are at a higher risk for cardiovascular diseases, with studies indicating that about one-third of diabetes patients may have concurrent heart conditions [7][8] - Early detection and management of pre-diabetes can prevent the progression to full-blown diabetes, highlighting the importance of regular monitoring [8] Group 5: Future Directions - The "Healthy China Action" plan aims to improve diabetes management services and increase the treatment and control rates of diabetes by 2030 [8]

Core Insights - The 28th Annual Academic Conference of the Chinese Society of Clinical Oncology (CSCO) was held in Jinan, Shandong, where experts shared cutting-edge research and clinical experiences in oncology [1][4] - The "2025 People's Good Doctor Cancer Prevention and Treatment Science Popularization Action" exhibition was launched, focusing on cancer prevention and treatment [3][5] Group 1: Cancer Prevention Strategies - The core strategy for cancer prevention is the "three-level prevention," which requires tailored science popularization strategies for different populations [4] - For the general public, the focus should be on cultivating healthy lifestyles, such as balanced diets, regular exercise, and avoiding smoking and excessive drinking [4] - High-risk groups require targeted early screening education, explaining risk factors, early symptoms, and screening methods to promote early diagnosis and treatment [4] Group 2: Role of Healthcare Professionals - Multidisciplinary collaboration is essential for comprehensive cancer management, with science popularization being a crucial component [4][5] - Healthcare professionals have a responsibility to translate complex treatment concepts into understandable language for patients to avoid delays in treatment due to misunderstandings [4] Group 3: Importance of Science Popularization - The science popularization exhibition serves as a platform for knowledge dissemination and a bridge for communication between medical professionals and the public [5] - Effective science popularization can transform reactive treatment into proactive prevention, reducing potential health risks and economic burdens [5][6] - The exhibition aims to inspire more healthcare workers to create quality science popularization content, contributing to the Healthy China 2030 goal [5] Group 4: Corporate Responsibility - Qilu Pharmaceutical Company emphasized its commitment to social responsibility and the importance of science education in cancer prevention [6] - The company aims to support cancer prevention initiatives and promote high-quality science popularization to benefit the public [6] Group 5: Innovations in Science Popularization - Experts discussed the need for continuous innovation in the forms and content of science popularization [10] - The use of artificial intelligence, such as Q&A robots and personalized content delivery, can enhance the precision and convenience of science popularization services [10] - Establishing incentive mechanisms for healthcare professionals to engage in science popularization is crucial for making cancer prevention knowledge accessible to the public [10]