Equity – Asia Research Presentation：大药的诞生，才是医药的未来 The Birth of Major Drugs: The Future of Medicine 因此，以供需结构为基石、以产业升级为锚点开展细分研究是十分必要的，并应结合当下中国资本市场的主要政策导向分析，得出2026 年医药行业投资策略。 余文心Wenxin Yu wenxin.yu@htisec.com 彭娉Ping Peng p.peng@htisec.com 孟陆Lu Meng l.meng@htisec.com 5 Nov 2025 本研究报告由海通国际分销，海通国际是由海通国际研究有限公司，海通证券印度私人有限公司，海通国际株式会社和海通国际证券集团其他各成员单位的证券 研究团队所组成的全球品牌，海通国际证券集团各成员分别在其许可的司法管辖区内从事证券活动。关于海通国际的分析师证明，重要披露声明和免责声明，请 参阅附录。(Pleaseseeappendix for English translation ofthe disclaimer) 国泰海通证券2026年度策略会 序言 老龄化、城镇化、疾病 ...

Core Viewpoint - The company demonstrates strong long-term growth potential through innovative value realization, with a significant partnership with Pfizer for the SSGJ-707 drug, which is expected to enhance its market position in oncology treatments [1][2]. Financial Performance - In the first half of 2025, the company reported a net profit of 1.358 billion yuan, reflecting a year-on-year increase of 24.61% - Revenue for the same period was 4.355 billion yuan, showing a slight decline of 0.77% - The gross margin stood at 85.31%, down by 1.20 percentage points, while the net profit margin increased to 31.88%, up by 6.65 percentage points [1]. Research and Development - R&D expenditure reached 548 million yuan, marking a 15% increase - The company generated a net operating cash flow of 970 million yuan and held nearly 8 billion yuan in cash reserves [1]. Strategic Partnerships - The company entered a significant collaboration with Pfizer regarding the SSGJ-707 drug, granting Pfizer global rights while retaining supply rights in mainland China - SSGJ-707 is set to undergo global Phase III clinical trials for treating non-small cell lung cancer (NSCLC) and other tumor types, with promising results from Phase II trials indicating its potential [1]. Product Pipeline - The company has a robust pipeline with 30 projects, including several in oncology and autoimmune diseases - Notable advancements include the approval of PD-1/HER2 and PD-1/PD-L1 dual antibodies for Phase II trials, and the first targeted MUC17/CD3/CD28 tri-antibody entering Phase I trials - In the autoimmune sector, IL-17A and IL-1β monoclonal antibodies have submitted NDA applications, while IL-4Rα monoclonal antibody has reached primary endpoints in Phase III trials [2]. Market Position and Future Outlook - The company is well-positioned in the "next-generation IO+ADC" space, with ongoing validation of SSGJ-707's trial speed and efficacy - The combination of a solid existing portfolio and the anticipated value from upcoming pipelines is expected to enhance the company's valuation [2].

Investment Rating - The investment rating for the company is "Buy" (maintained) [1][6][15] Core Views - The company demonstrated strong innovation value realization capabilities, with a net profit of 1.358 billion yuan in H1 2025, representing a year-on-year increase of 24.61%. Revenue for the same period was 4.355 billion yuan, slightly down by 0.77% [6] - The company has a robust pipeline with 30 projects, including several innovative drugs that are entering harvest periods. The collaboration with Pfizer on SSGJ-707 is expected to enhance the company's market position [7][8] Financial Summary - For H1 2025, the company reported a gross margin of 85.31% (down 1.20 percentage points) and a net margin of 31.88% (up 6.65 percentage points) [6] - R&D expenditure for H1 2025 was 548 million yuan, an increase of 15% year-on-year. The operating cash flow net amount was 970 million yuan, with nearly 8 billion yuan in cash on hand [6] - The company forecasts net profits of 2.328 billion yuan, 2.612 billion yuan, and 2.938 billion yuan for 2025, 2026, and 2027 respectively, with corresponding EPS of 0.96 yuan, 1.07 yuan, and 1.21 yuan per share [6][10] Market Performance - The current stock price is 29.96 HKD, with a market capitalization of 72.871 billion HKD. The stock has seen a 135.78% turnover rate over the past three months [1][10]