Group 1: Market Performance - Bilibili-W (09626) rose over 4% due to growth in gaming and advertising, with Bank of America raising the target price to HKD 211 [1] - Innovation drugs continue to attract funding, with companies like 3SBio (01530) up over 8%, CanSino Biologics (09926) up over 12%, and others reaching historical highs [1] - DaMai Entertainment (01060) increased over 5% as it became the official channel for Scottish Super League matches, indicating growth in sports ticketing [1] Group 2: Industry Developments - The National Healthcare Security Administration of China initiated the 11th batch of centralized drug procurement, focusing on mature "old drugs" and excluding innovative drugs from the procurement [1] - In the first half of this year, the total amount of License out for Chinese innovative drugs approached USD 66 billion, surpassing the total BD transaction amount for 2024, indicating sustained interest from multinational corporations [1] Group 3: Company-Specific News - Meitu (01357) rose over 5% due to significant progress in overseas lifestyle and productivity scene expansion, including a strategic partnership with Alibaba [2] - Tengsheng Bo Pharmaceutical-B (02137) increased over 7% after granting exclusive rights for a new drug in Greater China to Health元 Group [2] - Smoore International (06969) fell over 2% as it expects a profit decline of up to 35% in the first half of the year due to increased expenses [2] Group 4: Notable Stock Movements - Blueport Interactive (08267) surged over 40% after establishing the LK Crypto division to accelerate Web3 and RWA layout [2] - Gilead Sciences-B (01672) saw an early morning increase of over 11% as clinical research for ASC47 in treating obesity was completed [2] - MicroPort Medical (0853.HK) rose over 6% as it considers a non-binding proposal to restructure its CRM business [3]

Industry Investment Rating - The industry investment rating is "Outperform the Market" and is maintained [2] Core Viewpoints - The report highlights that Maiwei Biotech has achieved two licensing agreements, which will enhance cash flow and may indicate a turning point in its operations [5][14] - The pharmaceutical and biotechnology sector has seen a 1.6% increase this week, underperforming the CSI 300 index by 0.35 percentage points, ranking 23rd among 31 sub-industries [7][20] - The report emphasizes the accelerating trend in licensing out Chinese innovative drugs, with the total licensing amount exceeding 51.9 billion USD in 2024, marking a 27.4% year-on-year increase [18][19] Summary by Sections Weekly Insights - Maiwei Biotech's recent licensing agreements include a 25 million USD upfront payment and potential milestone payments totaling up to 571 million USD with CALICO Life Sciences for IL-11 targeted therapy, and a 3.8 billion CNY upfront payment with Qilu Pharmaceutical for 8MW0511 [5][14][15] - The report notes that the cash flow issues for Maiwei Biotech are expected to be significantly alleviated due to these agreements, with further business development opportunities anticipated [6] Subsector Performance - The pharmaceutical and biotechnology sector increased by 1.6% this week, with all sub-sectors showing growth. The hospital sector had the highest increase at 3.92% [7][24] - The report identifies key investment opportunities in various subsectors, including innovative drugs, medical devices, and medical consumables, with specific companies recommended for investment [8][28][29][30] Recommended and Benefiting Stocks - Recommended stocks include Innovent Biologics, Hengrui Medicine, and medical device companies such as YK Medical and Mindray Medical [8][31] - Benefiting stocks in the innovative drug sector include companies like Zai Lab, BeiGene, and others in both A-shares and H-shares [8][34][35] Market Trends - The report indicates that the innovative drug sector is expected to continue its upward trajectory, driven by strong clinical data and increased business development activities [28] - The medical device sector is projected to benefit from government policies promoting equipment upgrades, with a significant increase in procurement expected in the second quarter of 2025 [29][30]

Core Viewpoint - The focus of investment has shifted from AI to innovative pharmaceuticals, with significant interest and funding directed towards the latter, as evidenced by attendance at recent strategy meetings and substantial capital inflows into the sector [1][4]. Group 1: Market Trends - Innovative pharmaceuticals have seen a surge in investment, with southbound funds increasing their holdings by 55.14 billion, three times more than new consumer sectors [4]. - The healthcare sector's share of Hong Kong stock trading volume has risen from less than 5% a year ago to 15% [4]. - The top ten public funds this year are dominated by innovative pharmaceutical funds, indicating a shift in market sentiment and investment strategies [4][5]. Group 2: Fund Manager Insights - Fund manager Zhou Sicong has noted a correlation between the performance of innovative pharmaceuticals and AI, suggesting that when one sector performs well, the other may not [2][3]. - Zhou has observed that TMT fund managers are increasingly involved in innovative pharmaceuticals, indicating a broader interest in the sector [3]. - The current market dynamics have led to a new generation of fund managers emerging as leaders in the innovative pharmaceutical space, while traditional managers have struggled [5][21]. Group 3: Investment Opportunities - The introduction of ADC (Antibody-Drug Conjugates) has proven the value of innovative pharmaceuticals, leading to significant licensing deals and collaborations with major global pharmaceutical companies [10][11]. - The potential for licensing out agreements is projected to account for nearly 30% of global sales in the coming years, highlighting a key growth area for innovative pharmaceuticals [11]. - The market is increasingly recognizing the strength of Chinese innovative pharmaceuticals, with a shift in how these assets are valued and perceived globally [12][21]. Group 4: Valuation and Market Sentiment - The traditional valuation methods for innovative pharmaceuticals are being challenged, with new metrics emerging that reflect the changing landscape of the industry [17][18]. - The current excitement around innovative pharmaceuticals is contrasted with previous market downturns, suggesting a more optimistic outlook for the sector moving forward [21][22]. - Despite concerns about potential bubbles in the market, there is a growing belief in the long-term potential of Chinese innovative pharmaceuticals to surpass their global counterparts [21][22].