而在此前不久，锦波生物控股股东、实际控制人杨霞已将其持有的575.33万股股票转让给杭州久视，占 公司总股本的5%，共计14.03亿元。据了解，养生堂与杭州久视的实控人均为钟睒睒。 21世纪经济报道记者韩利明 近期，北交所"重组胶原蛋白第一股"锦波生物公告显示，拟向养生堂发行不超过717.56万股股份，占发 行前公司总股本的6.24%，发行价格为278.72元/股，募资总额不超过20亿元，用于人源化胶原蛋白FAST 数据库与产品开发平台项目等。该申请已获北交所受理。 据《福布斯中国内地富豪榜》，2024年钟睒睒凭借508亿美元身家成功蝉联中国内地首富；进入2025 年，《福布斯全球亿万富豪榜》显示，其在内地富豪中的排名落于张一鸣之后。 值得关注的是，锦波生物是其继万泰生物（603392）后，再次重资投入的生物技术领域企业。在这背 后，万泰生物作为曾经风光无限的国产HPV疫苗头部企业，自2023年起业绩出现持续下滑，这也使得市 场对钟睒睒此次新入局的锦波生物及背后的医美赛道更为关注。 从行业大环境来看，近年来我国医美市场需求呈现旺盛且多元的发展态势，上游产品技术的迭代创新与 现有产品适应症的不断扩展，持续丰富着 ...

Core Insights - JD Health has entered the medical beauty sector with the opening of its first self-operated clinic in Beijing Yizhuang, named "JD Medical Beauty (Yizhuang Store)" [1] - This marks the first physical store launch after the establishment of JD Health's medical beauty subsidiary in March 2023, with a second store set to open on September 30 in Beijing's Guomao area [1] - The Yizhuang store is integrated within JD Health's comprehensive outpatient department and offers popular light medical beauty services such as skin whitening, water light beauty, wrinkle removal, and anti-aging treatments [1] - The JD Medical Beauty services are accessible through the JD App, allowing users to search for "medical beauty" and navigate to the dedicated channel for services [1] - JD Medical Beauty has also launched a WeChat mini-program for additional accessibility [1] Trademark Registration - Beijing JD 360 Degrees E-commerce Co., Ltd. has applied for multiple "JD Medical Beauty" trademarks, covering international classifications such as advertising sales, medical gardening, and scientific instruments, with many trademarks currently awaiting substantive examination [4]

Core Viewpoint - The medical beauty industry is experiencing a significant transformation as pharmaceutical companies and beauty brands aggressively enter the market, indicating a restructuring of industry boundaries driven by consumer upgrades and technological revolutions [1][9]. Group 1: Industry Dynamics - Major pharmaceutical players are rapidly entering the medical beauty sector, with all four major pharmaceutical distribution giants—Sinopharm, Shanghai Pharmaceuticals, China Resources Pharmaceutical, and Jiuzhoutong—now involved in the medical beauty space [3][5]. - Jiuzhoutong was the first to recognize the potential of the medical beauty market, investing in Aimeike in 2016 and subsequently collaborating with other companies, achieving a significant increase in its medical beauty service institutions to 10,560, a year-on-year growth of 84.81% [5][9]. - The medical beauty market in China is projected to reach a scale of 638.2 billion yuan by 2030, with a compound annual growth rate (CAGR) of 14.5% from 2021 to 2030 [9]. Group 2: Investment Trends - Notable investments include Zhong Shanshan, the former richest man in China, who invested 3.4 billion yuan in Jinbo Biotechnology, becoming its second-largest shareholder, highlighting the growing interest in the collagen market [6][9]. - Jiuzhoutong reported a significant increase in its medical beauty revenue, achieving 851 million yuan in sales for 2024, a year-on-year increase of 120.47%, with a three-year CAGR of 111.64% [9]. Group 3: Market Opportunities - The medical beauty sector is attracting beauty brands, with companies like Chuangyan Biotechnology and Proya entering the market with medical-grade products, indicating a shift towards higher-quality offerings [12][13]. - The demand for medical-grade products is rising, with single-use medical dressings priced between 15 to 35 yuan, reflecting consumers' willingness to pay for higher-quality solutions [13]. Group 4: Competitive Strategies - Companies are adopting various strategies to enter the medical beauty market, including investment and acquisition, technology extension, brand crossover, channel integration, and medical-research collaboration [15]. - The future winners in the medical beauty space are expected to be those who can integrate the entire supply chain from research to sales, emphasizing safety and effectiveness in product offerings [15].

Core Viewpoint - Lepu Medical, a leader in cardiovascular devices, has officially entered the dermatology field with the approval of its self-developed polylactic acid facial filler, "童颜针" (Tongyan Needle), marking a significant milestone for the company amid declining performance in recent years [1][5][6]. Company Developments - The "童颜针" is a dermal filler designed to correct moderate to severe nasolabial folds, utilizing polylactic acid (PLLA) which is biodegradable and safe for human use [5][6]. - The product's approval is seen as a key event for Lepu Medical, enhancing its consumer healthcare business and providing new options for both doctors and consumers [5][6]. - The company has been actively expanding into the ophthalmology and dermatology sectors, with several products in various stages of development, including hyaluronic acid gels [5][7]. Financial Performance - Lepu Medical's financial performance has deteriorated significantly, with a projected net profit decline of over 80% in 2024, marking the worst performance since its listing in 2009 [1][7]. - In 2023, the company reported a revenue of approximately 79.8 billion yuan, a year-on-year decrease of 24.78%, and a net profit of about 12.58 billion yuan, down 42.91% [7]. - For 2024, the expected revenue is around 61.03 billion yuan, a decline of 23.52%, with a net profit of approximately 2.47 billion yuan [7][8]. R&D and Market Position - Despite a decline in R&D expenses and personnel, the proportion of R&D investment relative to revenue has increased, indicating a strategic focus on innovation [9][10]. - The number of R&D personnel decreased by over 20% from 2023 to 2024, reflecting potential adjustments in the company's strategic direction [9][10]. - The competitive landscape for the "童颜针" market is intensifying, with seven similar products already approved in China, suggesting a need for Lepu Medical to leverage its technological advantages to stand out [6][7].

Group 1 - The core viewpoint is that Lepu Medical has officially entered the aesthetic medicine market with the approval of its self-developed polylactic acid facial filler, marking a significant strategic move into consumer healthcare [1][2] - The newly approved product is expected to fill a gap in the dermatology field and is seen as a milestone for the company, with anticipated positive contributions to its performance [2][3] - The company is facing declining growth in its main business, with a reported revenue of 1.736 billion yuan in Q1 2024, down 9.67% year-on-year, and a net profit of 379 million yuan, down 21.44% year-on-year, indicating a need for new growth avenues [3] Group 2 - Lepu Medical's ambitions in the aesthetic field extend beyond the facial filler, as its subsidiary has submitted an application for a botulinum toxin product, targeting a domestic market worth over 6 billion yuan [4] - The aesthetic medicine market is becoming increasingly competitive, with several existing products already in the market, including those from competitors like Aimeike and Sihuan Pharmaceutical [2][5] - The entry of major pharmaceutical companies into the aesthetic market indicates a shift towards a more robust and competitive landscape, where Lepu Medical's experience in medical device development may provide a commercial advantage [5]

证券之星：于莹 4月17日，欧莱雅公布了2025年第一季度财报，数据显示，报告期内，公司实现了117.3亿欧元的销售额，同比增长4.4%。 梳理了欧莱雅近5年一季度的业绩情况，证券之星发现，其第一季度销售额均保持增长，但增幅整体呈现下滑态势，并于今 年创下近5年来最低增幅。而细看其财报数据，去年表现亮眼、曾被寄予厚望的"皮肤科学美容"业务今年一季度增长明显放 缓。 | | 欧莱雅集团近5年第一季度销售额及增幅 | | | --- | --- | --- | | 年份 | 销售额(亿人民币) | 同比涨幅 | | 2025 | 972. 04 | 4. 40% | | 2024 | 931. 34 | 8. 30% | | 2023 | 860. 08 | 13.00% | | 2022 | 750. 7 | 19.00% | | 2021 | 630. 56 | 11. 50% | 值得一提的是，2024年，欧莱雅在中国市场遭遇了罕见的"倒春寒"。在财报中，公司曾表示，中国市场十年来首次出现负 增长，以至于整体业绩增长都被拖累。而今年一季度，中国市场的表现再度成为关注的重点，虽然公司未披露具体数据， 但就在近 ...

Core Insights - Huadong Medicine (000963) reported a stable growth trend in Q1 2025, achieving operating revenue of 10.736 billion yuan, a year-on-year increase of 3.12%, and a net profit attributable to shareholders of 915 million yuan, up 6.06% [1] - The company's core pharmaceutical industrial segment continued to perform well, with its subsidiary, China-U.S. Huadong, generating revenue of 3.621 billion yuan, a 6.52% increase, and a net profit of 843 million yuan, up 12.20% [1] - The sales of innovative drugs, particularly the biosimilar drug Ustinumab injection (Sailixin), have shown strong market performance, with over 800 hospitals prescribing it as of March 31, 2025 [1] Business Segments - The pharmaceutical industrial R&D investment reached 880 million yuan in Q1 2025, a 49.60% increase year-on-year, with direct R&D spending of 600 million yuan, up 71.77%, accounting for 16.67% of pharmaceutical industrial revenue [2] - Huadong Medicine is focusing its innovative R&D efforts on three key areas: endocrinology, autoimmune diseases, and oncology, with several important milestones achieved in Q1 2025 [2] - The medical aesthetics segment generated approximately 238 million yuan in revenue in Q1 2025, reflecting a 24.37% increase compared to Q4 2024, with 40 high-end products in the international market [2]