Core Viewpoint - The article highlights the increasing concern over shingles, also known as "snake around the waist," which is caused by the varicella-zoster virus and can remain dormant in the body for years, particularly affecting individuals over 50 and those with weakened immune systems [1][2][3]. Group 1: Health Impact - Shingles can cause severe and prolonged pain, often described by patients as excruciating, with 5%-30% of patients experiencing postherpetic neuralgia, which can last for months or even decades [2]. - Over 90% of adults carry the varicella-zoster virus, and approximately one-third of individuals will develop shingles in their lifetime [2]. Group 2: Vulnerable Populations - Individuals with chronic diseases, such as hypertension and cardiovascular conditions, are at a higher risk for shingles due to compromised immune systems [3]. - Diabetic patients face a 60% higher risk of developing shingles compared to the general population, which can complicate blood sugar management and increase hospitalization risks [3]. Group 3: Prevention Strategies - Vaccination is emphasized as a crucial preventive measure for individuals over 50, especially those with chronic illnesses or weakened immune systems [4]. - Evidence from both domestic and international studies supports the recommendation for older adults and those with chronic conditions to receive shingles vaccinations to reduce the incidence of infectious diseases [4].