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细胞抗衰
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当时间成为稀缺资本:精英们的身体投资逻辑是什么?
3 6 Ke· 2025-08-22 12:02
Core Insights - Health is emerging as a critical variable in "time economics," influencing the productivity and value derived from time allocation [4][8] - The decline in health is leading to significant economic losses, with global productivity losses due to health crises estimated at over $15 trillion annually, equivalent to 17% of global GDP [6] - Investment in health, particularly through innovations like NAD+ supplementation, is seen as a means to extend both quality of life and wealth accumulation [11][12] Health as a Time Economic Variable - The concept of time as a scarce resource is being re-evaluated, with health now determining the marginal productivity of time [6][4] - In China, the prevalence of chronic conditions such as hypertension (27.5%) and high cholesterol (over 40%) indicates a widespread health depreciation [6] - The analogy of health investment to compound interest suggests that early health investments yield long-term benefits in productivity and wealth creation [8] NAD+ and Anti-Aging Technology - NAD+ has become a focal point in anti-aging research, recognized for its role in cellular metabolism and repair [11][12] - Research indicates that NAD+ levels decline significantly with age, dropping by approximately 50% every 20 years after age 30 [12] - The decline in NAD+ levels correlates with decreased energy metabolism and cellular repair capabilities, akin to asset depreciation in businesses [14] Target Demographics for NAD+ Supplementation - High-demand groups for NAD+ supplementation include celebrities and high-pressure professionals who require optimal physical and mental performance [15][17] - SwissePLUS has developed a range of NAD+ products tailored to different needs, emphasizing the importance of health management alongside financial asset management [17][29] SwissePLUS Product Offerings - The SwissePLUS product line includes various formulations designed to meet the needs of different demographics, from basic cellular repair to targeted anti-aging solutions [19][29] - The brand positions its NAD+ series not merely as nutritional supplements but as tools for sustainable body capital management, enhancing the quality of time rather than just its quantity [29]
当时间成为稀缺资本:精英们的身体投资逻辑是什么?
36氪· 2025-08-22 11:20
Core Viewpoint - Health is the true underlying capital that determines the value of time, and neglecting health can lead to a significant depreciation of time as a resource [4][10]. Group 1: Time Economics and Health - Time is a scarce resource that must be allocated optimally among various uses, and health significantly influences the marginal productivity of time [3][7]. - The global health crisis has resulted in productivity losses equivalent to over $15 trillion annually, representing 17% of the global economy [8]. - In China, the prevalence of chronic diseases such as hypertension (27.5%), hyperlipidemia (over 40%), and diabetes (nearly 12%) indicates a significant health crisis impacting productivity [8]. Group 2: Investment in Health and Longevity - The establishment of companies like Altos Labs, which focuses on cellular anti-aging, highlights the growing investment in health and longevity technologies, with significant backing from high-profile investors [12][14]. - NAD+ has emerged as a key molecule in cellular metabolism and repair, with its levels declining sharply with age, leading to decreased energy metabolism and cellular repair capabilities [15][17]. - Research institutions are exploring ways to enhance NAD+ levels through nutritional supplementation, making it a critical variable influencing health, time, and wealth [18]. Group 3: Target Audience for NAD+ Solutions - High-demand groups for NAD+ supplementation include celebrities, corporate executives, and high-intensity knowledge workers who require optimal physical and mental performance [20][22]. - SwissePLUS has developed a range of NAD+ products aimed at these demographics, demonstrating the importance of managing physical capital alongside financial assets [22][31]. Group 4: SwissePLUS Product Offerings - SwissePLUS offers a comprehensive cellular nutrition anti-aging solution, including products tailored to different needs and life stages, emphasizing the importance of health management as a proactive capital operation [24][30]. - The brand's mission is to provide sustainable body capital management tools that enhance the quality of time, rather than merely increasing its quantity [31].
Cell:刘光慧团队开发抗衰祖细胞疗法,成功延缓灵长类多器官衰老,为人类衰老干预带来新范式
生物世界· 2025-06-13 14:18
Core Viewpoint - The research highlights the development of engineered human mesenchymal progenitor cells (SRC) that exhibit triple resistance to aging, stress, and malignant transformation, providing a customizable cell therapy paradigm for aging intervention in primates [3][12]. Group 1: Research Background and Mechanism - Aging is characterized by the depletion of stem cell reserves, leading to decreased tissue regeneration and homeostasis, which is a key feature of aging and age-related diseases [2]. - The study published in Cell by a collaborative research team from the Chinese Academy of Sciences and Capital Medical University focuses on the mechanisms of aging regulation and the potential of SRC to counteract aging in primates [2][3]. Group 2: Development of SRC Technology - The research team utilized synthetic biology to reprogram longevity gene pathways, successfully constructing SRC with enhanced anti-aging properties [3]. - The SRC technology has evolved through various iterations, including SRC 1.0 and SRC 2.0, which involved precise genetic modifications to enhance antioxidant defenses and integrate anti-aging functionalities [6][8]. Group 3: Efficacy and Safety of SRC - The SRC cells demonstrated significant anti-aging activity and environmental adaptability, with excellent safety profiles, effectively resisting adverse effects in a primate model [8][9]. - A 44-week intervention study using SRC in aged primates showed no adverse events, confirming the safety and immune tolerance of SRC transplantation [9][11]. Group 4: Mechanistic Insights and Outcomes - SRC cells were found to release exosomes that promote cellular rejuvenation, suppress chronic inflammation, and maintain genomic stability, contributing to the delay of systemic aging [11]. - The intervention led to improvements in cognitive function, reduction of degenerative changes in multiple tissues, and a significant reversal of biological aging markers in various organs [11][12]. Group 5: Clinical Translation and Future Prospects - The study establishes a theoretical framework for stem cell transplantation to mitigate aging, addressing long-standing controversies in the field [13]. - The research opens pathways for scalable production of universal cell interventions, providing new solutions for aging and related diseases, and sets a new standard for evaluating anti-aging effects in cell therapy products [14][16]. - Future research will focus on optimizing clinical-grade production processes and understanding the interactions between SRC and the host immune system to enhance treatment strategies [18][19].
燕之屋旗下YANPEP燕窝肽全新上市
Sou Hu Wang· 2025-05-27 03:34
Core Insights - YANPEP, a health management technology brand under Yanzhiwu, has launched new products centered around bird's nest peptides, aiming to provide comprehensive anti-aging solutions for consumers [1][5] - The company has set 2025 as a strategic milestone for its second entrepreneurial phase, focusing on expanding market value and achieving strategic goals [1] Group 1: Research and Development - Yanzhiwu has established a bird's nest peptide research center in January 2022, focusing on enzyme hydrolysis technology, active ingredient research, and product development [2] - The company has achieved significant advancements in production processes, including the granting of a national invention patent for a method of preparing bird's nest peptides with cell repair and whitening effects [2][3] - Yanzhiwu has published 60 research papers on bird's nest peptides, with 19 in international SCI journals, demonstrating a substantial increase in bioavailability compared to traditional bird's nest [3] Group 2: Market Position and Innovation - Yanzhiwu has been recognized as the "leading bird's nest" brand, having pioneered the field since 2015 with a CNAS accredited laboratory [2] - The company has developed a complete closed-loop system covering raw material preparation, functional verification, and product transformation, enhancing the biological activity of bird's nest peptides [3] - YANPEP aims to transform traditional consumption into a modern health lifestyle by integrating biotechnology, precision nutrition, and social experiences [5] Group 3: Scientific Validation and Future Directions - Research indicates that bird's nest peptides can delay aging through various mechanisms, including maintaining mitochondrial health and reducing chronic inflammation [4] - The future of bird's nest consumption is expected to evolve into a health management solution that quantifies and enhances traditional wisdom through scientific validation [5]
聚焦口服抗衰品类增长 NYO3与天猫国际达成战略合作
Sou Hu Wang· 2025-04-24 06:21
Core Insights - NYO3, a high-end dietary nutrition brand from Norway, has formed a strategic partnership with Tmall International to enhance business growth through cross-border e-commerce [1][2] - The collaboration aims to integrate Nordic health concepts with consumer needs, providing a model for global nutrition brands [2][10] Company Overview - NYO3 is recognized for its commitment to "pure nature from Norway," leveraging the nutritional benefits of pristine polar waters [2] - The brand has achieved significant accolades, including being named the leading global brand in krill oil sales for 2023 and receiving multiple international quality certifications [2][5] Market Positioning - The partnership with Tmall International is expected to expand NYO3's market influence in China and explore cross-border e-commerce collaboration between Norway and China [2][10] - NYO3's innovative product, Ageless Aurora Skin Capsule, targets common skin aging issues for women aged 25 and above, utilizing advanced phospholipid delivery technology [7][9] Product Innovation - The Ageless product line, developed in collaboration with Norway's NO-Age research center, combines krill oil with 14 premium ingredients to enhance cellular energy metabolism [7] - The product achieved top rankings in Tmall International's oral beauty category within its first month of launch, indicating strong market acceptance [7][10] Strategic Goals - The partnership is positioned as a mutual benefit, with NYO3 seeking a healthier platform ecosystem and Tmall International aiming to enhance user experience through differentiated products [2][10] - Future plans include multi-layered content marketing and expanding cross-border e-commerce operations to promote Nordic nutrition to Chinese consumers [10]