Core Insights - The mRNA sector shows signs of recovery since 2025, with significant acquisitions and advancements in technology by companies like AbbVie and BioNTech [1] - Domestic companies, while still in early stages, are beginning to emerge, with YunTing New Medicine showcasing three products based on its self-developed mRNA technology platform [1][2] Company Developments - YunTing New Medicine has developed three products: a universal therapeutic vaccine EVM14, a personalized therapeutic vaccine EVM16, and an autologous CAR-T project [1][2] - The company has integrated self-developed AI algorithms with a lipid nanoparticle (LNP) delivery system, completing three generations of AI algorithm upgrades to enhance protein expression levels [1][2] Clinical Progress - EVM14 has completed dual submissions in China and the U.S., with a global multi-center Phase I clinical trial expected to enroll its first patient in Q3 this year, targeting three major cancer types [2] - EVM16 has shown promising preliminary data, demonstrating good immunogenicity even at low starting doses in advanced cancer patients [2] Industry Trends - In the past two years, business development (BD) has become a key performance indicator for domestic innovative pharmaceutical companies, with Chinese assets contributing nearly 50% of upfront payments in global oncology licensing deals this year [2][3] - The mRNA technology platform offers advantages in drug development across various difficult-to-treat diseases, transforming the process from "molecular screening" to "information design" [2] Strategic Considerations - YunTing New Medicine is not rushing into BD but is focused on making the right strategic decisions, with a cash reserve of 1.6 billion yuan by the end of 2024, allowing for continued development without external capital [3] - The timing and structure of BD are critical, as having clinical data can significantly increase the value of licensing agreements compared to preclinical stages [3][4]

Group 1: Northern Huachuang (北方华创) - The company is positioned as a leading domestic semiconductor equipment manufacturer, showcasing both growth potential and resilience [1] - The domestic semiconductor equipment market share in China has increased from 13% in 2015 to an estimated 42% in 2024, with Northern Huachuang expected to double its market share by 2025 compared to 2020 [2] - The company’s current valuation at 27 times NTM P/E is close to historical lows, suggesting an attractive investment opportunity with a target price of RMB 530, indicating a potential upside of 19.6% [2] Group 2: Genscript Biotech (云顶新耀) - The company is advancing its platform for reversible mRNA therapies, with promising data from multiple drug candidates [3] - The EVM16 candidate has shown efficacy in mouse models and demonstrated synergy with PD-1 antibodies, while EVM14 is progressing through preclinical studies with potential for inducing immune memory [4] - The EVER001 study for treating membranous nephropathy has reported significant immunological responses, with antibody levels dropping by over 60% after 8-12 weeks [4][7] Group 3: Photovoltaic Industry - Recent policy discussions indicate a shift towards addressing the challenges faced by the photovoltaic industry, with expectations for substantive policies to emerge [8] - The report highlights opportunities for leading photovoltaic manufacturers, particularly in glass and silicon production, as the industry seeks to overcome competitive pressures [8] Group 4: Automotive Industry - The report notes a slowdown in the month-on-month growth of new energy vehicle deliveries, with a 17.7% year-on-year increase across 11 manufacturers [9] - BYD's June sales reached 377,628 units, reflecting an 11% year-on-year growth, while Xiaomi's deliveries exceeded 25,000 units despite slight month-on-month declines [10][11] - The overall market is expected to continue its growth trajectory in July, driven by new model launches from various manufacturers [11]