在新当选中国科学院院士的上海医院专家中，周俭致力于肝胆肿瘤临床和基础研究，曾5次获国家科技 进步奖；房静远专注于胃肠癌的防治。至此，中山医院现有包括葛均波、樊嘉、周俭3位中国科学院院 士；而仁济医院也拥有中国工程院院士夏强和中国科学院院士房静远2名院士。 从此次新增院士名单来看，肿瘤等重大疾病领域依然是院士聚集的高地。以周俭所在的肝癌领域为例， 全球每年新发肝癌病例约90万例，中国占比接近一半。 从此次新增院士名单来看，肿瘤等重大疾病领域依然是院士聚集的高地。 中国科学院、中国工程院11月21日公布2025年院士增选结果，分别选举产生中国科学院院士73人，中国 工程院院士71人。新当选的中国科学院院士中，生命科学和医学学部13人，来自上海的复旦大学附属中 山医院周俭和上海交大附属仁济医院房静远当选。 其他当选中国科学院院士的临床医学专家还包括浙江大学医学院附属邵逸夫医院蔡秀军、首都医科大学 附属北京天坛医院王拥军、中国医学科学院北京协和医院朱兰（女）。 周俭表示："这些成功经验有力证明，肝癌完全可以像高血压、糖尿病一样，被作为可防、可控、可治 的慢性病来管理。" 此外，周俭与樊嘉院士共同创建的miRNA肝癌早 ...

Core Insights - Obesity is a significant global public health issue, with a retrospective study revealing a 69.5% incidence of weight regain among patients who underwent sleeve gastrectomy (SG) [6][7] - The study identifies the third year post-surgery as a critical period for weight rebound, with 41.7% of patients experiencing a weight regain of 20% or more of their maximum weight loss, meeting the criteria for weight regain (WR) [6][7][8] Study Overview - The research included 676 patients who underwent SG at Shanghai Jiao Tong University from January 2011 to June 2022, with a median follow-up of three years [6][7] - Factors associated with higher postoperative total weight loss percentage (%TWL) included baseline age, initial BMI, male gender, and absence of hypertension [7] - Among 540 patients with complete follow-up at 1, 3, and 5 years, the rate of weight regain increased from 21.7% at year three to 32.6% at year five [7] Weight Change Patterns - Patients were categorized into three groups based on weight change trajectories: significant weight loss, moderate weight loss, and minimal weight loss [7] - The significant weight loss group had higher baseline BMI, waist circumference, fasting insulin, and insulin resistance index (HOMA-IR) compared to the minimal weight loss group [7] Implications for Future Research - The findings provide a scientific basis for identifying high-risk patients and developing preventive strategies against weight regain after SG [8]

记者：唐成卓、司晓帅 新华社音视频部制作 0:00 近日，流行病学研究领域专题文集"推进中国和国际队列研究"在位于长春市的吉林大学第一医院发布， 来自多国的研究人员齐聚一堂，共同探讨大规模队列研究的相关问题。 ...

新成立的脑机接口临床研究中心依托山西医科大学与清华大学医学院合作优势，以神经外科为核 心，联动神经内科、精神卫生科、康复医学科、医学影像科等多学科团队，配备复合手术室、智能手术 机器人等硬件。 该中心副主任连世忠介绍，中心主攻方向包括为偏瘫、脊髓损伤患者重建神经通路，缩短康复周 期；利用神经调控技术促进植物人等意识障碍患者苏醒等，未来还将联合高校、企业探索脑机接口在癫 痫、帕金森病、老年痴呆、强迫症等领域的应用。(记者 范丽芳) 患者李先生因脑干梗死陷入昏迷6个月，气管被切开，靠胃管尿管维持生命，日常生活都需要人照 护，家属既心疼又痛苦。山西医科大学第一医院多学科团队评估后计划下周为他进行智能可感知脑起搏 器植入术。 "DBS手术就像给大脑安装了智能调节器，新一代可感知脑起搏器调控脑功能的同时还能搜集并解 码脑电信号。"该院副院长、脑机接口临床研究中主任郭庚介绍，该疗法实现对大脑的输入和输出双向 通路，通过电脉冲精准调节异常脑区活动，它可逆、可调、可视，为患者提供了个体化治疗新路径。 "医生，我感觉脑子里的那根弦松了，20多年来从没有这样轻松过。"赵女士的言语间难掩激动。近 日，她作为山西首例接受DBS(脑深 ...

Core Viewpoint - The recent research from the University of California, Berkeley, challenges the traditional belief that high-calorie foods are the main cause of obesity, suggesting that the pleasure derived from eating can play a positive role in weight management [4][7]. Group 1: Research Findings - The study titled "Changes in neurotensin signalling drive hedonic devaluation in obesity" reveals that the enjoyment of food can help maintain energy balance, redefining the relationship between food pleasure and obesity [4][7]. - High-fat diets were shown to impair the brain's reward system, leading to reduced appetite for high-calorie foods in obese mice, despite weight gain [9][11]. - The research identified neurotensin (NTS) as a key player in this process, with high-fat diets significantly suppressing NTS expression, which is crucial for enhancing dopamine neuron activity during food enjoyment [11][12]. Group 2: Implications for Weight Management - Restoring NTS levels through dietary intervention or gene therapy resulted in obese mice regaining normal food responses, reducing overall food intake, and improving anxiety symptoms [12]. - The findings suggest a shift from traditional weight loss strategies focused on appetite suppression to approaches that enhance the brain's reward mechanisms related to food enjoyment, potentially leading to the development of "happy dieting" therapies [12]. - This research opens new avenues for addressing obesity and related metabolic disorders, emphasizing the intersection of neuroscience and nutrition [12].

Core Insights - The article discusses a significant research paper published in Cell Genomics, focusing on the multi-omic underpinnings of heterogeneous aging across multiple organ systems [4][6]. - The research aims to shift the paradigm of age-related disease management from a "divide and conquer" approach to a "unified prevention" strategy by understanding the molecular mechanisms of aging [7][9]. Research Objectives - The study aims to clarify the genetic associations between organ-specific aging and blood-based epigenetic aging, revealing phenotypic clusters related to heterogeneous aging across multiple organ systems [7]. - It seeks to identify candidate gene drug targets associated with these heterogeneous aging processes and evaluate opportunities for repurposing existing drugs [7]. - The research intends to uncover downstream proteomic and metabolomic effects driven by organ-specific and blood-based epigenetic aging, identifying detectable biomarkers [7]. - The study integrates findings to map the interaction networks of heterogeneous aging across multiple organ systems and their potential cross-layer molecular regulatory mechanisms [7][10]. Key Findings - The research team developed a framework based on R/Shiny, accessible online, providing a comprehensive multi-omic molecular map of heterogeneous aging [9]. - The study advances the understanding of aging heterogeneity, offering insights for precision medical strategies aimed at delaying organ-specific aging and preventing or treating related chronic diseases [9][10]. - Heterogeneous aging phenotypic clusters exhibit distinct biological characteristics, and genomic approaches have identified priority drug targets for addressing this aging heterogeneity [10].

新酷产品第一时间免费试玩，还有众多优质达人分享独到生活经验，快来新浪众测，体验各领域最前 沿、最有趣、最好玩的产品吧~！下载客户端还能获得专享福利哦！ 库克发微博 宣告与北京安贞医院及美国心脏协会携手，研究Apple Watch在心衰患者健康管理中的应用 引言：在全球范围内，心脏病始终是威胁人类生命的首要杀手。当科技的创新力量与医疗的专业权威相 遇，一场旨在改变心脏病管理模式的探索就此展开。 2025年10月16日，苹果公司CEO库克（Tim Cook）通过微博发声，宣告与北京安贞医院及美国心脏协 会携手，研究Apple Watch在心衰患者健康管理中的应用。这一消息背后，是苹果公司深耕中国医疗健 康领域、构建"科技+医疗"生态的关键一步，更是苹果公司长久布局、目标明确的临床研究实践。 一场有备而来的医疗探索 这场跨界合作并非偶然，而是苹果公司、北京安贞医院与美国心脏协会基于各自优势的精准对接，每一 方都在研究中扮演着不可或缺的角色。 从苹果公司的角度来看，其在中国医疗领域的布局早已埋下伏笔。此次合作的核心目标有两个，一是搭 建强大的临床医学专家网络，为其在健康领域的工作推广提供支持，同时助力相关技术通过国家 ...

Core Insights - The "Four Major Chronic Diseases" National Science and Technology Major Project has been launched in Jiangsu Taizhou, focusing on cancer, cardiovascular, respiratory, and metabolic disease prevention and control [1] Group 1: Project Overview - The project, approved in May 2023, is the only regional plan selected in the Yangtze River Delta and has a four-year implementation period [1] - The project aims to address key challenges in the prevention and control of chronic diseases by leveraging existing research capabilities [1] Group 2: Innovative Approaches - The project is based on the previous "Star Network Plan," which promotes an integrated chronic disease prevention and control model [1] - The core concept of the "Star Network Plan" is to empower grassroots healthcare through "Artificial Intelligence + Healthcare," shifting the focus from disease treatment to health promotion [1] Group 3: Healthcare Network Structure - The project aims to establish a four-tier chronic disease management network consisting of regional medical centers, county hospitals, central hospitals, and grassroots clinics [1] - It utilizes technologies such as the Internet of Things, artificial intelligence, and mobile wearable devices to enhance grassroots healthcare institutions [1] Group 4: Comprehensive Service Model - The initiative provides a full-process individualized prevention and treatment service, including prevention, screening, rescue, treatment, and rehabilitation [1] - The goal is to encourage chronic disease patients to return to community health services and to reintegrate rural doctors into the primary prevention and control efforts [1]

因此，上海中医药大学附属龙华医院凭借其在肿瘤领域的深厚临床积累，负责研究的整体设计与临床实 施；中国芳香疗法研究院作为国际疗法考试委员会(ITEC)认证的专业机构，为项目提供标准化的天然植 物精油原料与技术保障。这种优势互补的合作模式，旨在确保从干预材料到研究方法的全过程质量可 控，为产生高级别循证医学证据奠定坚实基础。 此次研究项目致力于探索一种高可及性、低负担的非药物解决方案，以应对肿瘤带来的疼痛、焦虑、恐 惧等心理社会挑战，相关研究成果有望为公共卫生领域的肿瘤心身管理提供新的选择方向。(记者陈植) 经济观察网2025年10月10日，上海中医药大学附属龙华医院与中国芳香疗法研究院宣布共同启动一项临 床观察研究项目，以探索药用植物来源精油对胰腺癌疼痛的辅助干预作用。 据悉，这个项目将基于中医"扶正治癌"理论，提出以药用植物来源精油为介质，重点评估此类精油通过 外用与嗅吸途径，在癌性疼痛管理过程的潜在价值，并系统探索其在肿瘤全周期管理中的应用前景。 癌性疼痛，特别是胰腺癌等难治性肿瘤引发的疼痛，严重影响患者的生活质量与治疗进程。当前医疗体 系虽已建立规范的疼痛药物治疗方案，但仍面临副作用、依赖性等挑战。 ...

Core Insights - Cell ferroptosis has been confirmed to be related to the development of various liver diseases [1] - A new study from Japan indicates that two volatile molecules produced during ferroptosis can be detected in the breath of patients [1] Group 1: Research Findings - Ferroptosis is a specific type of programmed cell death characterized by abnormal accumulation of iron ions and lipid peroxidation [1] - The main pathological process of ferroptosis involves irreversible damage to cell membrane structures due to lipid peroxidation, leading to loss of cell function [1] - Current detection methods for ferroptosis primarily rely on invasive tissue biopsies, which impose significant burdens on patients [1] Group 2: Methodology and Implications - Researchers from Kyoto University and other institutions utilized a newly developed oxidative volatile organic compound analysis technique to study volatile molecules released during ferroptosis [1] - The study identified two "iron-smelling molecules" that increase in concentration as ferroptosis progresses [1] - These molecules were found to be elevated in both the liver and breath of liver disease model mice, as well as in the breath of liver disease patients [1] Group 3: Future Applications - Based on the research findings, alternative methods to liver biopsy could be developed for health diagnostics and monitoring the progression of liver diseases [2] - The research results have been published in the journal "Redox Biology" [2]