星标 ★ IPO日报 精彩文章第一时间推送 近期，嘉必优生物技术（武汉）股份有限公司（下称"嘉必优"）公告称，拟以发行股份及支付现金的方式向王树伟、董栋等13名交易对方购买欧易 生物63.2134%的股权，并募集配套资金，交易价格8.31亿元。 嘉必优在2024年营收和净利润双增长，但其在2021年—2023年净利润波动剧烈。2023年净利润虽有所回升，但风险仍存。此次，公司以8.31亿元的溢价收 购欧易生物，未来业绩兑现存不确定性，机遇与挑战并存。 制图：佘诗婕 01 净利润不稳定 嘉必优成立于2004年，2019年12月在科创板上市。公司是国内较早从事微生物合成法生产多不饱和脂肪酸及脂溶性营养素的企业之一。主要产品为多不饱 和脂肪酸ARA（花生四烯酸）、藻油DHA（二十二碳六烯酸）等。这些产品广泛应用于婴幼儿配方食品、膳食营养补充剂、健康食品、特殊医学用途配 方食品以及动物营养、个护美妆等领域。客户方面，其与雀巢、达能、嘉吉、飞鹤、伊利、君乐宝等国内外知名企业建立了长期的合作关系。 2024年，嘉必优实现了营收和净利润的双增长。其营收为5.55亿元，同比增长25.06%；归母净利润为1.24亿元，同比增长 ...

Investment Rating - The investment rating for the company is "Buy" (maintained) [1] Core Views - The company is experiencing steady revenue growth in 2024, with a reported revenue of 419 million yuan, reflecting a year-on-year increase of 1.92%. However, the net profit attributable to the parent company is -129 million yuan, a significant decline of 70.79% year-on-year [4][7] - The company is focusing on the commercialization of its HIV drug, which is showing strong momentum, supported by clinical research evidence [5] - The acquisition of Nanda Pharmaceutical is part of the company's strategy to deepen its presence in the human protein business and create a second growth curve [6] Financial Summary - In 2024, the company's total assets increased by 9.35% to 1.91 billion yuan, while the equity attributable to the parent company decreased by 11.94% to 999 million yuan [4] - The company's revenue projections for 2024-2026 have been adjusted to -129 million yuan, -3 million yuan, and 21 million yuan respectively, with corresponding EPS of -0.31, -0.01, and 0.05 yuan per share [4] - The company's gross margin is expected to improve from 55.4% in 2024 to 70.2% in 2026, indicating a positive trend in profitability [7]

Investment Rating - The report assigns an investment rating of "Recommended" for the pharmaceutical and biotechnology industry [3][33]. Core Insights - The "AI + Healthcare/Pharmaceutical" theme continues to gain traction, with short-term momentum expected to persist. The report highlights significant stock performance in the sector, with the pharmaceutical and biotechnology sector (SW) rising by 2.71%, outperforming the CSI 300 index, and all sub-sectors showing positive growth, particularly in medical services [3][4]. - In the U.S., Tempus AI, a representative company in medical AI, saw a weekly increase of approximately 30% and over 160% year-to-date, driving the momentum of the medical AI concept. In China, companies like KingMed Diagnostics and Dian Diagnostics announced collaborations with DeepSeek, indicating a shift towards the commercialization of AI applications in healthcare [4][3]. - The report emphasizes investment opportunities in sub-sectors such as "AI + Medical Imaging," "AI + Diagnostic Services," and "AI + Drug Development," recommending key companies including United Imaging, Mindray, BGI Genomics, and WuXi AppTec [3][4]. Industry Performance Tracking - The pharmaceutical and biotechnology sector (SW) rose by 2.71% in the week of February 10-14, ranking 5th among 31 Shenwan primary industries. The CSI 300 index increased by 1.19% during the same period [5][6]. - All sub-sectors experienced growth, with medical services leading at +6.51%, followed by medical devices at +4.81%, and pharmaceutical commerce at +4.18% [5][6]. - Notable individual stock performances included Dian Diagnostics (+46.29%), Mian Health (+31.58%), and United Imaging (+27.33%) [6]. Industry Dynamics and Key Company Tracking - The National Healthcare Security Administration released a list of key tasks for 2025, focusing on efficient medical insurance processes and direct settlements for collected drugs and consumables [7]. - The retail terminal drug sales scale in China is projected to reach 574 billion yuan in 2024, with a growth rate of 3.7%, indicating a slowdown in growth due to demographic and economic factors [8]. - The report also notes significant collaborations, such as Baiyang Pharmaceutical's agreement with Roche for the exclusive marketing rights of a targeted cancer drug in mainland China [9][11]. Industry Data Tracking - The report tracks various industry metrics, including the basic medical insurance fund income, which reached 28,507.29 billion yuan in 2024, showing a year-on-year growth of 5% [15][16]. - The domestic pharmaceutical manufacturing industry achieved a total revenue of 25,298.50 billion yuan in 2024, with profit totals declining by 1.1% year-on-year [17].

Investment Rating - The report assigns an investment rating of "Recommended" for the pharmaceutical and biotechnology industry [3][33]. Core Insights - The "AI + Healthcare/Pharmaceutical" theme continues to gain traction, with short-term momentum expected to persist. The domestic and international markets are witnessing significant developments in AI applications within healthcare, particularly with companies like Tempus AI showing substantial stock price increases [3][4]. - The report highlights investment opportunities in specific segments such as "AI + Medical Imaging," "AI + Diagnostic Services," and "AI + Drug Development," recommending key companies including United Imaging, Mindray, BGI, and WuXi AppTec [3][4]. Industry Performance Tracking - The pharmaceutical and biotechnology sector (SW) rose by 2.71% last week, outperforming the CSI 300 index, which increased by 1.19%. All sub-sectors within the industry experienced growth, with medical services leading at +6.51% [5][6]. - Notable individual stock performances included Dean Diagnostics (+46.29%) and Meinian Health (+31.58%), while stocks like Betta Pharmaceuticals saw declines of -11.36% [6]. Industry Dynamics and Key Company Tracking - The National Healthcare Security Administration released a list of key tasks for 2025, focusing on efficient medical insurance processes and direct settlements for collected drugs and consumables [7]. - Recent collaborations include Baiyang Pharmaceutical signing a commercialization agreement with Roche for the drug Rituximab, and Sanofi Biologics partnering with Baili Tianheng to explore new treatment potentials in oncology [11][12]. Industry Data Tracking - The retail terminal drug sales in China are projected to reach CNY 574 billion in 2024, with a growth rate of 3.7%, indicating a slowdown compared to previous years [8]. - The medical insurance fund's income for 2024 is reported at CNY 28,507.29 billion, reflecting a year-on-year growth of 5.00% [15][16]. - The domestic pharmaceutical manufacturing industry achieved a total revenue of CNY 25,298.50 billion in 2024, remaining stable compared to the previous year [17].

对标胶原蛋白，具"爆品"潜质 据QYR预测，2023-2029年全球PDRN市场规模CAGR达到43.32%，其中中国地区CAGR可达到49%，虽然国内 PDRN行业已开始进入高速增长期，但由于原料本土化规模生产的问题才得到解决，以及终端市场目前还没有 大量的应用产品推出，当下市场规模仍然偏低。然而通过比对PDRN与胶原蛋白，我们认为中国PDRN市场， 随着原料本土规模化生产所带来的价格降低，以及护肤和医美领域的产品上市，其发展进度将远超预期。我们 认为PDRN将成为求美领域下一个"爆品"级赛道。 自研+资本，华熙系已成为PDRN的国家队 点击注册小程序 特别申明： 本订阅号中所涉及的证券研究信息由光大证券研究所编写，仅面向光大证券专业投资者客户，用作新媒体形势下研究 信息和研究观点的沟通交流。非光大证券专业投资者客户，请勿订阅、接收或使用本订阅号中的任何信息。本订阅号 难以设置访问权限，若给您造成不便，敬请谅解。光大证券研究所不会因关注、收到或阅读本订阅号推送内容而视相 关人员为光大证券的客户。 报告摘要 PDRN——再生医学领域的"液体黄金" PDRN（多聚脱氧核糖核苷酸）是一种长度50-2000 bp、 ...

润本生物技术股份有限公司 首次公开发行股票并在主板上市 网上路演公告 本次拟公开发行股份 60,690,000 股，占本次公开发行后总股本的 15.00%。 回拨机制启动前，网下初始发行数量为 42,483,000 股，占本次发行总量的 70.00%； 网上初始发行数量为 18,207,000 股，占本次发行总量的 30.00%。网上及网下最 终发行数量将根据回拨情况确定。 为便于投资者了解发行人的有关情况和本次发行的相关安排，发行人和本次 发行的保荐人（主承销商）将就本次发行举行网上路演，敬请广大投资者关注。 1、网上路演时间：2023 年 9 月 26 日（T-1 日，周二）14:00-17:00 2、网上路演网址： 上证路演中心：http://roadshow.sseinfo.com 上海证券报·中国证券网：https://roadshow.cnstock.com/ 3、参加人员：发行人董事会及管理层主要成员和保荐人（主承销商）相关 人员。 保荐人（主承销商）：申万宏源证券承销保荐有限责任公司 润本生物技术股份有限公司（以下简称"润本股份"、"发行人"或"公司"） 首次公开发行人民币普通股（A 股）并在 ...