Pharmaceutical Sector - The pharmaceutical sector in China is showing strong performance, with significant transactions such as the $1.25 billion deal enhancing market confidence in the quality and market value of Chinese innovative drugs [1] - Chinese pharmaceutical companies are increasingly making their mark in global licensing transactions and showcasing their clinical pipeline potential at major conferences like ASCO [2] - The outlook for the pharmaceutical sector is optimistic, with expectations of a reversal in market trends by 2025, driven by innovative drugs and the recovery of left-side sectors [1][2] Biopharmaceuticals - GSK announced FDA approval for mepolizumab as an additional maintenance treatment for poorly controlled chronic obstructive pulmonary disease (COPD) patients, with projected global sales of €1.784 billion in 2024 [3] - There is a growing interest in IL-5 targeted drugs, with several domestic companies already engaged in this area [3] Medical Services & Consumer Healthcare - Alcon reported Q1 2025 surgical business net sales of $1.338 billion, a 1% year-on-year decline, but a 2% increase at constant exchange rates [4] - Vision care business net sales reached $1.106 billion in Q1 2025, reflecting a 1% year-on-year growth, driven by innovations in contact lenses [4] Medical Devices - Johnson & Johnson Medical launched the SOUNDSTAR CRYSTAL ultrasound catheter in the U.S. for cardiac ablation procedures, indicating a rich pipeline of innovative products [5] - There is a strong long-term demand trend for innovative medical devices, with a focus on leading companies that are expected to rapidly scale new products [5] Pharmacies - A recent initiative by multiple government departments aims to enhance the health promotion functions of retail pharmacies, indicating a supportive policy environment for non-drug product expansion [6] - Continuous optimization of industry regulations and the implementation of drug traceability measures are expected to create a more favorable environment for pharmacies [6]

5月19日至5月25日，券商给予上市公司目标价共223次，按最新收盘价计算，目标价涨幅排名居前的公 司有凯因科技、亚信安全、今世缘，目标价涨幅分别为68.49%、67.84%、65.93%，分别属于生物制 品、软件开发、白酒行业。 | | | | 5月19日全5月25日目标价获幅排名 | | | | | | --- | --- | --- | --- | --- | --- | --- | --- | | 证券代码 证券名称 | | 机构 | 最新评级 | 废局日标0 | | | 行业 | | 688687 | 凯因科技 | 华泰金融控股(香港) | 头人 | 44. 97 | 26. 69 | 68. 49 | 生物制品 | | 688225 | 亚信安全 | 国泰海通证券 | 增持 | 33. 40 | 19. 90 | 67.84 | 软件开发 | | 603369 | 今世缘 | 华创证券 | 强推 | 75.00 | 45. 20 | 65. 93 | 日酒 | | 600519 | 贵州茅台 | 华创证券 | 强推 | 2600. 00 | 1572. 60 | 65. 33 | 日酒 | | 6 ...

Core Viewpoint - The stock price of Giant Bio (HK02367) experienced a significant decline following allegations of product fraud related to its brand, Kefu Mei, which led to a public statement denying the accusations and asserting compliance with regulatory standards [9][10]. Group 1: Company Performance - As of May 26, Giant Bio's stock opened with a drop exceeding 8%, later narrowing to a decline of 3.52% [1]. - The company's market capitalization is approximately 80 billion HKD [11]. - Kefu Mei, a brand under Giant Bio, reported sales revenue exceeding 4.5 billion CNY in 2024, reflecting a year-on-year growth of 62.9% [10]. Group 2: Industry Context - The A-share market saw a collective decline in stocks related to recombinant protein, with notable drops in companies such as Ruizhi Pharmaceutical and Sanofi Guojian, each falling nearly 6% [2]. - The market reaction indicates a broader concern regarding the credibility of companies in the recombinant protein sector following the allegations against Giant Bio [2].

北交所策略专题报告 2025 年 05 月 25 日 北交所排队企业整体高质量，关注 2025 打新机会 北交所研究团队 ——北交所策略专题报告 诸海滨（分析师） zhuhaibin@kysec.cn 证书编号：S0790522080007 专题：北交所排队企业整体高质量，关注 2025 北交所打新机会 上市节奏角度来看，2024 年全年北交所共上市 23 只新股。截至 2025 年 5 月 23 日，2025 年 1-5 月北交所共上市 4 家企业。从发审会节奏上来看，随着申报企业 补充 2024 年报数据的结束，下周 2 家公司上会审核，未来节奏或有提升。从首 发募集资金角度的中签率来看，募集资金较高的企业申购中签率同样较高，2024 至今北交所合计上市 27 家企业中签率均值达 0.09%，但其中首发募集资金超过 2 个亿企业的平均中签率在 0.14%，首发募集低于 2 个亿企业的平均中签率在 0.06%。从当前北交所排队企业看利润体量整体有所较高，截至 2025 年 5 月 23 日，94 家排队中企业 2024 年归母净利润均值达 8967.02 万元，高于 266 家北交 所企业 2024 年归母 ...

截至2025年5月23日收盘，上海莱士（002252）报收于6.8元，较上周的6.76元上涨0.59%。本周，上海 莱士5月22日盘中最高价报6.93元。5月19日盘中最低价报6.73元。上海莱士当前最新总市值451.38亿 元，在生物制品板块市值排名3/50，在两市A股市值排名290/5148。 公司公告汇总 关于控股股东增持股份计划的公告。证券代码：002252 证券简称：上海莱士 公告编号：2025-043。控 股股东海盈康（青岛）医疗科技有限公司基于对公司未来发展的信心和长期投资价值的认同，计划自本 公告披露之日起6个月内，通过深圳证券交易所交易系统以集中竞价交易方式增持公司股份，增持总金 额不低于人民币25,000万元，且不超过人民币50,000万元，不设置价格区间。本次增持计划资金来源为 自有资金及股份增持专项贷款，其中专项贷款资金占比不超过90%，中国银行股份有限公司青岛市分行 为海盈康提供不超过4.5亿元的股票增持专项贷款支持。海盈康承诺在增持期间及法定期限内不减持公 司股份，不进行内幕交易、短线交易等行为。本次增持计划不触及要约收购，不会导致公司股权分布不 符合上市条件，不会导致公司控制权发 ...

中国通号：中标总计约37.89亿元轨道交通市场重要项目 5月23日晚，中国通号（688009）发布公告称，公司在2025年3月至4月共中标十一个轨道交通市场重要 项目，包括铁路市场8个和城市轨道交通市场3个。以上项目中标金额总计约为37.89亿元，约占该公司 中国会计准则下2024年经审计营业收入的11.67%。因为上述项目跨年分期实施，对2025年当期业绩影 响有不确定性。 资料显示，中国通号成立于2010年12月，主营业务是轨道交通控制系统及其衍生业务，同时开展轨道交 通配套工程施工业务、市政信息化及其配套工程总承包业务和海外轨道交通建设相关业务等。 所属行业：机械设备–轨交设备Ⅱ–轨交设备Ⅲ 新柴股份：拟使用不超过5亿元闲置资金购买理财产品 5月23日晚，新柴股份（301032）发布公告称，公司计划使用不超过5亿元的闲置自有资金购买安全性 高、流动性好、中低风险的结构性存款、收益凭证等理财产品。该计划旨在提高资金使用效率，增加现 金资产收益。 资料显示，新柴股份成立于2007年6月，主营业务是非道路用柴油发动机及相关零部件的研发、生产与 销售。 所属行业：机械设备–通用设备–其他通用设备 5月23日晚， ...

广发证券研报称，当前时刻我们建议重视港股创新药。中国创新药出海的全球竞争优势正在凸显。近年 来，中国药企在海外市场的License-out交易实现了跨越式发展。NewCo模式的兴起，进一步为原药企解 决了融资难、变现难、研发风险大等问题。2023年下半年以来，政策层面出现了一系列积极信号，包括 但不限于规则优化、创新药支持政策加码等。财报层面：头部港股创新药公司受益于License-out放量， 营收和利润稳步增长。估值层面：医药板块相比于其他成长行业，估值处于相对安全的区间。 （本文机构观点来自持牌证券机构，不构成任何投资建议，亦不代表平台观点，请投资人独立判断和决 策。） 风险提示：基金管理人依照恪尽职守、诚实信用、谨慎勤勉的原则管理和运用基金财产，但不保证基金 一定盈利，也不保证最低收益。基金的过往业绩并不预示其未来表现,基金管理人管理的其他基金的业 绩并不构成基金业绩表现的保证。港股通创新药ETF工银为指数基金，主要采用完全复制策略，跟踪标 的指数市场表现，具有与标的指数、以及标的指数所代表的股票市场相似的风险收益特征。本基金还将 投资港股通投资标的股票，还需承担汇率风险和港股通机制下因投资环境、投资 ...

市场表现： 2025 年5 月22 日，医药板块涨跌幅-0.73%，跑输沪深300 指数0.67pct，涨跌幅居申万31 个子行业第14 名。各医药子行业中，医疗研发外包(+0.04%)、血液制品(-0.37%)、其他生物制品（-0.51%）表现居 前，医院（-1.83%)、线下药店(-1.65%)、医药流通（-1.37%)表现居后。个股方面，日涨幅榜前3 位分别 为三生国健(+20.00%)、亚虹医药(+12.26%)、迈威生物(+11.71%)；跌幅榜前3 位为赛升药业 （-11.63%）、拓新药业(-10.93%)、拱东医疗（-9.99%)。 行业要闻： 近日，Ionis 宣布，公司开发的反义寡核苷酸（ASO）疗法Tryngolza（Olezarsen）在Essence 临床3 期研 究中取得积极的顶线结果。数据显示，该药在治疗6 个月后显著降低了患者的甘油三酯水平，达到主要 终点，且在所有关键次要终点上也取得统计学显著改善。Olezarsen 是一种反义寡核苷酸疗法，旨在抑 制机体产生载脂蛋白C-III（apoC-III，一种在肝脏中产生的调节血液中TG 代谢的蛋白）。 风险提示：新药研发及上市不及预 ...

Market Overview - On May 22, major market indices collectively retreated, with a total trading volume of 1.14 trillion yuan, a decrease of 74.7 billion yuan compared to the previous day [1] - The number of stocks that rose was less than 900, while nearly 4,500 stocks declined, with 51 stocks hitting the daily limit up and 18 stocks hitting the daily limit down [1] - Industry sectors experienced widespread declines, with beauty care, social services, and basic chemicals dropping over 1.5%, while only banking, media, and household appliances saw gains [1] Stockholder Changes - A total of 365 stocks reported changes in shareholder numbers as of May 20, with 170 stocks seeing a decrease in shareholder accounts compared to May 10 [2] - The stock with the largest decline in shareholder accounts was Shanshui Bide, which saw a 33.18% drop to 4,909 accounts [2] - Ji Qi Co., Ltd. also reported a significant decrease of 15.50% in shareholder accounts, totaling 17,413 [2] Institutional Trading - On May 22, 10 stocks saw net purchases from institutions, with Tianqi Mould and Aerospace Nanhu receiving over 50 million yuan in net buying [3] - The stock San Sheng Guo Jian faced the largest net selling from institutions, amounting to 151 million yuan, following a 100% increase in price over four consecutive days of hitting the daily limit up [3][4] - The institutional trading data indicates a trend of increasing net selling for San Sheng Guo Jian over three consecutive days [3] Northbound Capital Flow - On May 22, seven stocks experienced net buying from northbound funds, with San Sheng Guo Jian leading at 35.03 million yuan [5] - The stock Lianyun Port saw the highest net selling from northbound funds, totaling 51.66 million yuan [5] Important Announcements - Chao Da Equipment was selected for the 2025 Jiangsu Province Advanced Intelligent Factory list for its smart collaborative manufacturing project [6] - Bo Rui Pharmaceutical received a drug registration certificate for Iopamidol injection from the National Medical Products Administration [6] - Chengdu Xian Dao's shareholder plans to increase its stake in the company by 25 to 50 million yuan without a set price range [6] - Xinhua Insurance signed a contract to establish a private equity fund with a total scale of 20 billion yuan, contributing 10 billion yuan [6] - Zhongnan Media's subsidiary signed a government procurement contract worth 1.009 billion yuan, positively impacting the company's operations in 2025 [6]

相关研究报告 医药生物/生物制品 三生制药（01530.HK） 2025 年 05 月 22 日 投资评级：买入（维持） | 日期 | 2025/5/21 | | --- | --- | | 当前股价(港元) | 20.850 | | 一年最高最低(港元) | 22.000/5.470 | | 总市值(亿港元) | 500.10 | | 流通市值(亿港元) | 500.10 | | 总股本(亿股) | 23.99 | | 流通港股(亿股) | 23.99 | | 近 3 个月换手率(%) | 134.69 | 股价走势图 数据来源：聚源 -80% 0% 80% 160% 240% 320% 2024-05 2024-09 2025-01 三生制药 恒生指数 《核心品种持续发力，多款创新药进 入收获期—港股公司首次覆盖报告》 -2025.3.27 与辉瑞就 SSGJ-707 达成授权，创新价值弹性兑现 ——港股公司信息更新报告 | 余汝意（分析师） | 余克清（分析师） | 刘艺（联系人） | | --- | --- | --- | | yuruyi@kysec.cn | yukeqing@kysec.cn | ...