Group 1 - The China Securities Regulatory Commission (CSRC) has requested Huaheng Biological (688639.SH) to provide supplementary information regarding its technology export business and compliance over the past three years [1] - Huaheng Biological has submitted a listing application to the Hong Kong Stock Exchange, with Huatai International as the sole sponsor [1] - The CSRC has outlined specific areas for Huaheng Biological to clarify, including the status of its technology export business, compliance with regulations, and the use of raised funds for overseas investments [1] Group 2 - Huaheng Biological is a pioneer in synthetic biology, focusing on the research, large-scale production, and commercialization of bio-based products [2] - The company is recognized as one of the most comprehensive enterprises globally in commercial applications of bio-based products through synthetic biology [2] - Huaheng Biological is the first company to industrialize the anaerobic fermentation of a series of amino acids, including L-Alanine and L-Valine, and holds the largest market share for these products globally as of 2024 [2]

Group 1 - The China Securities Regulatory Commission (CSRC) has requested Huaheng Biological (688639.SH) to provide supplementary information regarding its technology export business and compliance over the past three years [1] - Huaheng Biological has submitted its listing application to the Hong Kong Stock Exchange, with Huatai International as the sole sponsor [1] - The CSRC has outlined specific areas for Huaheng Biological to clarify, including the status of its technology export business, compliance with regulations, and the use of raised funds for overseas investments [1] Group 2 - Huaheng Biological is a pioneer in synthetic biology, focusing on the research, large-scale production, and commercialization of bio-based products [2] - The company is recognized as one of the most comprehensive enterprises globally for commercial applications of bio-based products through synthetic biology [2] - Huaheng Biological is the first company in the world to industrialize the anaerobic fermentation of a series of amino acids, including L-Alanine and L-Valine, and holds the largest market share for these products globally as of 2024 [2]

Core Insights - Anhui Huaheng Biotechnology Co., Ltd. has submitted a listing application to the Hong Kong Stock Exchange, with Huatai International as the exclusive sponsor [1] Company Overview - The company is a pioneer in synthetic biology, focusing on the research, large-scale production, and commercialization of bio-based products through biomanufacturing technology [3] - It has established a leading position in the industry over 20 years, with strong R&D capabilities and mature mass production capabilities [3] - According to Frost & Sullivan, the company is one of the most comprehensive producers of bio-based products commercialized through synthetic biology globally [3] Market Position - The company is the first globally to industrialize a series of amino acids (including L-Alanine and L-Valine) through anaerobic fermentation [3] - By 2024, the company holds the largest market share for L-Alanine and L-Valine globally [3] Client Relationships - As of June 30, 2025, the company has established stable long-term partnerships with over 768 clients across 85 countries in Asia, Europe, and America [5] Product Portfolio - The company's bio-based products include: - Amino acid series (mainly alanine series, L-Valine, Tryptophan, Arginine) - Vitamin series (mainly D-Calcium Pantothenate, D-Pantothenol, Inositol) - Other bio-based products (mainly bio-based new material monomers like 1,3-Propanediol and Succinic Acid, Malic Acid, Arbutin) [5] - These products are widely used in various industries, including animal nutrition, personal care, food and beverage, advanced materials, and plant nutrition [5] Manufacturing Technology - The company employs two green manufacturing technology platforms: fermentation and enzyme catalysis, focusing on microbial cell factories and enzyme-based production processes [7] - Its biomanufacturing methods replace traditional chemical synthesis with renewable biological resources, reducing pollution, energy consumption, and carbon footprint [7] Financial Performance - The company's revenue and gross profit for the fiscal years are as follows: - FY2022: Revenue of RMB 1.418 billion, Gross Profit of RMB 548 million, Gross Margin of 38.7% - FY2023: Revenue of RMB 1.938 billion, Gross Profit of RMB 782 million, Gross Margin of 40.4% - FY2024: Revenue of RMB 2.178 billion, Gross Profit of RMB 540 million, Gross Margin of 24.8% - H1 2024: Revenue of RMB 1.016 billion, Gross Profit of RMB 321 million, Gross Margin of 31.6% - H1 2025: Revenue of RMB 1.489 billion, Gross Profit of RMB 350 million, Gross Margin of 23.5% [7] Use of Proceeds - The funds raised from the listing will be used for: - Accelerating global expansion and layout - Development of synthetic biology enabling technologies, new products, and solutions - Capacity upgrades - Working capital supplementation and other general corporate purposes [7]

Core Viewpoint - Anhui Huaheng Biotechnology Co., Ltd. has submitted an application for listing on the Hong Kong Stock Exchange, with Huatai International as the sole sponsor [1] Company Overview - Huaheng Biotechnology is a pioneer in synthetic biotechnology, focusing on the research, large-scale production, and commercialization of bio-based products [3] - The company has established a leading position in the industry through two decades of experience in biomanufacturing, with strong R&D capabilities and mature mass production capabilities [3] Market Position - According to Frost & Sullivan, Huaheng is one of the most comprehensive companies in the commercial application of bio-based products through synthetic biotechnology [3] - The company is the first globally to industrialize the anaerobic fermentation of a series of amino acids, including L-Alanine and L-Valine, and holds the largest market share for these products as of 2024 [3] Client Relationships - As of June 30, 2025, the company has established stable long-term partnerships with over 768 clients across 85 countries in major markets including Asia, Europe, and America [4] Product Portfolio - The main bio-based products include amino acids (primarily alanine series, L-Valine, tryptophan, arginine), vitamins (D-Calcium Pantothenate, D-Pantothenol, inositol), and other bio-based products [4] - The products are widely used in various industries such as animal nutrition, personal care, food and beverage, advanced materials, and plant nutrition [4] Manufacturing Technology - The company employs two green manufacturing technology platforms: fermentation and enzyme catalysis, focusing on microbial cell factories and enzyme-based production processes [4] - This technology aims to replace traditional chemical synthesis with renewable biological resources, reducing pollution and energy consumption while minimizing carbon footprints [4] Market Growth - The global bio-based products market is projected to grow from USD 22.8 billion in 2020 to USD 42.1 billion by 2024, with a compound annual growth rate (CAGR) of 16.6% [5] - The market is expected to further increase to USD 80.1 billion by 2030 and USD 109.1 billion by 2035, with a CAGR of 11.3% from 2024 to 2030 and 6.4% from 2030 to 2035 [5] Financial Performance - The company's revenue for the years 2022, 2023, 2024, and the first half of 2025 was approximately RMB 1.419 billion, RMB 1.938 billion, RMB 2.178 billion, and RMB 1.489 billion respectively [5] - The corresponding profits for the same periods were approximately RMB 319 million, RMB 447 million, RMB 185 million, and RMB 109 million [5][6]

Core Viewpoint - The company has announced a delay in the "Malic Acid Co-production Tryptophan Project," extending the expected operational date from 2025 to October 2026 due to project implementation and investment progress considerations [5][6][7]. Fundraising and Investment Project Overview - The company raised approximately RMB 699.99 million through a private placement of 21,122,510 shares at RMB 33.14 per share, with net proceeds after expenses amounting to RMB 683.81 million [1][2]. - The total planned investment for the projects was adjusted from RMB 700 million to RMB 683.81 million, with specific allocations for projects detailed in a table [2][3]. Fund Usage and Project Status - As of June 30, 2025, the company has fully utilized the raised funds for the "Succinic Acid Co-production Valine/Inositol Project" and the "Malic Acid Co-production Tryptophan Project," with investment ratios exceeding 100% for both projects [4]. - The company has established a special account for the management of the raised funds, ensuring compliance with regulatory requirements [2][3]. Delay Reasons and Impact - The delay in the "Malic Acid Co-production Tryptophan Project" is based on the need for technical upgrades to production equipment and alignment with market demand [5][6]. - The company asserts that the delay will not affect the project's investment direction, implementation entity, or method, and it does not pose any risk to shareholder interests [6][7]. Approval and Compliance - The board of directors and the supervisory board have approved the delay, and the decision complies with relevant regulations and internal governance [7][8].

Core Viewpoint - The report outlines the continuous supervision and compliance of Anhui Huaheng Biotechnology Co., Ltd. during its A-share issuance, emphasizing the company's adherence to regulations and the absence of any legal violations or breaches of commitments during the supervision period [1][2][3]. Continuous Supervision Work - The sponsor, Industrial Securities, has established a work plan and signed a continuous supervision agreement with Huaheng Biotechnology, detailing rights and obligations during the supervision period [1][2]. - Regular communication and visits are conducted to monitor the operational status of Huaheng Biotechnology [1][2]. Compliance and Governance - Huaheng Biotechnology has not reported any legal violations or breaches of commitments during the supervision period [2][3]. - The company has been urged to enhance its corporate governance and strictly adhere to relevant regulations [2][3]. Financial Performance - For the first half of 2025, the company's operating income reached approximately 1.49 billion yuan, a 46.54% increase compared to the same period in 2024 [11]. - The net profit attributable to shareholders decreased by 23.26% to approximately 114.89 million yuan [11]. - The total assets of the company increased by 6.26% to approximately 5.30 billion yuan as of June 30, 2025 [12]. Core Competitiveness - The company has established a strong technological foundation in microbial fermentation and enzyme production processes, achieving significant breakthroughs in anaerobic fermentation technology [13][15]. - Huaheng Biotechnology maintains a competitive edge through its extensive customer base, including partnerships with Fortune 500 companies [14]. Research and Development - The company invested approximately 68.67 million yuan in R&D during the first half of 2025, an increase of 8.40% compared to the previous year [17]. - The R&D expenditure accounted for 4.61% of the operating income, reflecting a decrease of 1.62 percentage points from the previous year [17]. Risk Factors - The company faces potential risks related to core competitiveness, operational challenges, and financial management, including fluctuations in raw material prices and safety risks associated with production processes [5][6][8]. - The international trade environment poses additional risks, particularly concerning export sales and compliance with foreign regulations [7][10].

Core Viewpoint - The strategic partnership between Huaheng Biotechnology and Evonik aims to leverage their respective strengths to provide high-quality bio-based amino acid products, promoting innovation and development in the animal nutrition sector [2][4][5]. Group 1: Strategic Partnership - Huaheng Biotechnology and Evonik signed a memorandum of understanding to collaborate on bio-based amino acids for animal nutrition [2]. - Evonik has over 60 years of experience in essential amino acids for animal nutrition, providing a mature solution and extensive global marketing network [4]. - The partnership will integrate resources to enhance the supply chain and offer superior products and services, contributing to sustainable development in the global animal nutrition and feed industry [4]. Group 2: Project Developments - Huaheng Biotechnology plans to adjust its production projects, maintaining a total capacity of 50,000 tons per year for bio-based succinic acid and introducing flexible production for L-valine and myo-inositol [6]. - The company is investing 39 million yuan in an AI-driven bio-manufacturing research and pilot demonstration base, expected to achieve a comprehensive pilot scale of 5,500 tons [7]. - A project for resource utilization of amino acid mother liquor is set with an investment of 40 million yuan, aiming for an annual production capacity of 26,000 tons of peptide granules [8]. Group 3: Future Initiatives - Huaheng Biotechnology announced plans to invest 320 million yuan in an AI precision fermentation and protein engineering shared demonstration project, focusing on real-time monitoring and optimization of production processes [9]. - The company is preparing for an overseas share issuance and plans to list on the Hong Kong Stock Exchange [9]. Group 4: Upcoming Events - The 2025 Synthetic Biology and Green Bio-Manufacturing Conference will be held in Ningbo, focusing on AI and bio-manufacturing, with various forums and discussions scheduled [11][12].

Group 1 - The core point of the article is that Huaheng Biological (688639.SH) is planning to issue overseas shares (H-shares) and list on the Hong Kong Stock Exchange to enhance its global development strategy and brand influence [1] - The company aims to optimize its capital structure, broaden financing channels, and improve governance and overall strength through this H-share listing [1] - The specific details of the H-share listing are still under discussion with relevant intermediaries, and it will not lead to changes in the controlling shareholder or actual controller of the company [1] Group 2 - Huaheng Biological was listed on the A-share market in 2021 and focuses on synthetic biology technology, primarily engaged in the R&D, production, and sales of bio-based products [3] - The company's main products include amino acids, vitamins, bio-based new material monomers, and other products, which are widely used in various fields such as intermediates, animal nutrition, personal care, functional foods, and plant nutrition [3] - The company has established a sustainable innovation capability through its Hefei Research Institute and has high-quality delivery capabilities across four production bases located in Changfeng, Qinhuangdao, Bayannaoer, and Chifeng [3]

Core Viewpoint - Anhui Huaheng Biological Technology Co., Ltd. reported a significant increase in overseas revenue for 2024, driven primarily by growth in amino acid product sales and the introduction of new products [2][19]. Group 1: Overseas Revenue Performance - The company achieved overseas revenue of 1.032 billion yuan in 2024, accounting for 47.39% of total revenue, representing a year-on-year growth of 30.34% [2][19]. - The breakdown of overseas revenue shows that the main business revenue increased by 30.34% to 1.032 billion yuan, while other business revenue rose by 88.86% to 40.65 million yuan [2][5]. - The primary regions for overseas sales include Europe, America, and Asia, with varying gross profit margins due to differences in product structure [5][19]. Group 2: Audit Procedures and Findings - The annual audit firm conducted thorough procedures to verify the authenticity and accuracy of overseas revenue, including internal control evaluations and document checks [7][8]. - The audit confirmed that 74.73% of overseas revenue was verified through customer confirmations, indicating a high level of reliability in reported figures [9][21]. - The audit also matched overseas sales data with third-party data, such as export tax refund claims and foreign exchange management bureau data, revealing minimal discrepancies [11][12]. Group 3: Gross Margin Analysis - The company's overall gross margin for 2024 was reported at 24.92%, a decline of 15.60 percentage points from the previous year, primarily due to decreased margins in amino acid and vitamin products [21][22]. - The average selling prices for amino acids and vitamins fell significantly, with L-valine prices dropping by 17.89% and vitamin prices by 54.09% [23][24]. - The decline in gross margins is attributed to increased competition and market dynamics, with the company implementing measures to address these challenges [27][35]. Group 4: Future Outlook and Industry Trends - The demand for amino acids is expected to grow due to trends in precision nutrition and reduced reliance on traditional feed ingredients, which may positively impact future margins [27][29]. - The global market for biosynthetic vitamins is projected to grow significantly, indicating potential opportunities for the company as it expands its product offerings [29][30]. - The company is positioned to benefit from technological advancements in production processes, which may enhance cost efficiency and product competitiveness in the long term [31][32].

Project Overview - The project is named "Annual Production of 12,000 Tons of Bio-based Tryptophan Renovation and Expansion Project" [2] - The construction unit is Qinhuangdao Huaheng Biological Engineering Co., Ltd. [2] - The project is located in the Shanhaiguan District of Qinhuangdao City, Hebei Province [2] Project Details - The total construction area is 37,075 square meters [2] - The project will utilize bio-based malic acid and its derivatives, including fermentation systems and extraction equipment [2] - The project aims to maintain the existing production capacity of malic acid and its derivatives while achieving a flexible production of 12,000 tons/year of tryptophan [2] Existing Infrastructure - Qinhuangdao Huaheng Biological Engineering Co., Ltd. currently operates three fermentation workshops, one refining workshop, one extraction workshop, and additional facilities including a wastewater treatment station and warehouses [2]