Core Viewpoint - The article discusses the advancements in synthetic biology, particularly focusing on optimizing yeast metabolism for carbon conservation and fixation, which is crucial for reducing CO2 emissions and achieving sustainable chemical production [3][4][5]. Summary by Sections 1. Introduction to Carbon Emissions and Synthetic Biology - The increasing use of fossil resources is leading to higher CO2 emissions, raising global concerns about climate change and the urgent need for alternative solutions to achieve carbon neutrality [4]. - Synthetic biology enables the use of inexpensive substrates, such as lignocellulose, for chemical production, thereby reducing reliance on fossil resources [4]. 2. Yeast as a Platform for Biomanufacturing - Yeast is highlighted as a robust microbial chassis for industrial biomanufacturing, capable of producing various compounds like terpenes and fatty acids [5]. - The complexity of yeast metabolism often results in unavoidable CO2 release during chemical synthesis, primarily through glycolysis, pentose phosphate pathway, and tricarboxylic acid cycle [5][6]. 3. Carbon Conservation Systems in Yeast - The article reviews recent advancements in constructing carbon conservation and fixation systems in yeast, focusing on avoiding unnecessary decarboxylation reactions to reduce carbon loss [6][8]. - Strategies include enhancing natural carboxylation reactions to promote carbon conservation, with specific examples of engineered yeast strains achieving significant improvements in product yields [8][11]. 4. Engineering Strategies and Results - Various engineering strategies are discussed, such as the non-oxidative glycolysis (NOG) pathway, which has been successfully implemented in yeast to improve carbon efficiency and product yields [10][11]. - Specific results include a 25% increase in β-farnesene yield and an 80% increase in β-carotene production through metabolic engineering [11][12]. 5. Future Directions in Low-Carbon Yeast Cell Factories - The future of biomanufacturing involves constructing low-carbon yeast cell factories that can recycle CO2 released during production and potentially utilize CO2 directly as a substrate for product synthesis [19][20]. - The article outlines the integration of carbon fixation pathways, such as the Calvin cycle and reductive glycine pathways, into yeast to enhance CO2 utilization [19][21]. 6. Conclusion - The advancements in synthetic biology and metabolic engineering present promising opportunities for developing sustainable biomanufacturing processes that significantly reduce carbon emissions and enhance product yields [3][4][5].

Core Viewpoint - The article highlights the upcoming SynBioCon 2025 event, focusing on the potential of synthetic biology and biomanufacturing, showcasing innovative research teams, technologies, and products in the field [2][5]. Group 1: Event Overview - The SynBioCon 2025 will take place from August 20-22 in Ningbo, Zhejiang, featuring a special session called the "Biomanufacturing Youth Forum" with nearly 30 presentations [2][10]. - The event aims to facilitate the exchange of innovative research outcomes and promote collaboration between researchers and industry stakeholders [2][14]. Group 2: Forum Details - The Youth Forum will include presentations from various universities and research institutions, such as Anhui University of Technology and South China University of Technology [4]. - The forum is designed to help attendees understand key scientific issues, solutions, and future development directions in the biomanufacturing sector within a 15-minute timeframe [3][14]. Group 3: Special Activities - A closed-door high-level seminar will discuss the trends and growth points of biomanufacturing as part of the event's agenda [11]. - The event will also feature project roadshows and technology showcases, inviting participation from leading parks and investment institutions [14][20]. Group 4: Thematic Discussions - The conference will cover various topics, including green chemicals, new materials, AI in biomanufacturing, and future food and agriculture [15][17][19]. - Specific discussions will focus on the development of bio-based materials, non-grain carbon source utilization, and the application of AI in enhancing biomanufacturing processes [18][22].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, discussing innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by various academic and industry institutions, including Peking University and the China Society of Biotechnology [2]. Group 3: Highlights of the Conference - Key highlights include forums and closed-door discussions on biomanufacturing trends, youth innovation technology sharing, and over 100 financing project roadshows to discover new cooperation opportunities [5]. - The event will gather leading enterprises, top universities, investment institutions, and industry stakeholders to foster collaboration [5]. Group 4: Agenda and Activities - The first day features a closed-door seminar focusing on the development trends and growth points of biomanufacturing, inviting 30 industry leaders and experts for in-depth discussions [9]. - The second and third days will include a macro forum on biomanufacturing, specialized sessions on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [13][15][18]. Group 5: Specialized Topics - Specialized discussions will cover topics such as the development of bio-based chemicals, AI applications in biomanufacturing, and the use of non-grain carbon sources for bioconversion [16][17]. - The conference will also address the synthesis of high-value food ingredients and the role of biotechnology in health and beauty products [20].

Core Viewpoint - The article highlights the upcoming SynBioCon 2025 event, focusing on the potential of synthetic biology and biomanufacturing, showcasing innovative research teams, technologies, and products in the field [2][5][14]. Group 1: Event Overview - The SynBioCon 2025 will take place from August 20-22 in Ningbo, Zhejiang, featuring a special session called the "Biomanufacturing Youth Forum" with nearly 30 presentations [2][10]. - The event aims to facilitate the exchange of innovative research outcomes and promote collaboration between researchers and industry stakeholders [2][14]. Group 2: Forum Details - The Youth Forum will include presentations from various universities and research institutions, such as Anhui University of Technology and South China University of Technology [4][5]. - The forum is designed to help attendees understand key scientific issues, solutions, and future development directions in biomanufacturing within a 15-minute format [3][14]. Group 3: Special Activities - A closed-door high-level seminar will discuss the trends and growth points of biomanufacturing as part of the event's agenda [11]. - The event will also feature project roadshows and technology showcases, inviting participation from leading parks and investment institutions [14][20]. Group 4: Thematic Discussions - The conference will cover various topics, including green chemicals, new materials, AI in biomanufacturing, and future food and agriculture [15][17][19]. - Specific focus areas include the development of bio-based materials, non-grain carbon source utilization, and the application of AI in enhancing biomanufacturing processes [18][22].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing, along with four major application areas: green chemicals and new materials, future food, future agriculture, and beauty raw materials [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan period and identify innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by Ningbo Meisai Biological Engineering Co., Ltd. It is supported by various professional committees and alliances in the field of biomanufacturing [2]. Group 3: Highlights of the Conference - The conference will feature forums and closed-door activities to gain insights into the development trends of biomanufacturing, explore new products and technologies, and foster new collaborations [4]. - There will be over 100 financing project roadshows to discover new cooperation opportunities and showcase innovative technological achievements [4]. - Key industry leaders, top universities, capital from parks, and the entire industry chain will gather to discuss advancements and opportunities in biomanufacturing [4]. Group 4: Agenda and Activities - The first day will include a closed-door seminar focusing on the development trends and growth points of biomanufacturing during the 14th Five-Year Plan, inviting 30 industry leaders and experts for in-depth discussions [9]. - The second and third days will feature a macro forum on biomanufacturing, specialized sub-forums on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials, addressing various key topics and innovations in these fields [13]. - A special session for showcasing scientific achievements and project matchmaking will also be held, inviting 100 innovative projects in the biomanufacturing sector for display and collaboration [14].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan and identify innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by various institutions, including the Chinese Society of Biotechnology and the Zhejiang Synthetic Biology Industry Technology Alliance [2]. Group 3: Conference Highlights - Key highlights include forums and closed-door discussions on biomanufacturing trends, youth innovation technology sharing, and over 100 financing project roadshows to discover new cooperation opportunities [4]. - The event will gather leading enterprises, top universities, investment institutions, and industry stakeholders to foster collaboration [4]. Group 4: Agenda and Activities - The first day features a closed-door seminar focusing on the development trends and growth points of biomanufacturing, inviting 30 industry leaders and experts for in-depth discussions [9]. - The second and third days will include a macro forum on biomanufacturing, specialized sub-forums on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [13]. Group 5: Specialized Topics - Sub-forums will cover various topics, including the development of bio-based chemicals, AI applications in enzyme discovery, and the biomanufacturing of high-value food ingredients [13]. - The conference will also showcase innovative projects and facilitate connections between research teams and industry players [12][14].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, discussing innovative technologies and products that can sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detai Zhongyan Information Technology Co., Ltd. (DT New Materials) and co-organized by Ningbo Meisai Biological Engineering Co., Ltd. [2]. - Supporting organizations include the Chinese Society of Biotechnology's Biobased Materials Committee and various local industry alliances [2]. Group 3: Highlights of the Conference - The conference will feature forums and closed-door activities to gain insights into the development trends of biomanufacturing and explore new products, technologies, and collaborations [5]. - There will be over 100 financing project roadshows to discover new cooperation opportunities [5]. - Key industry leaders, top universities, and investment institutions will gather to discuss advancements in the biomanufacturing sector [5]. Group 4: Agenda and Activities - The first day will include a closed-door seminar focusing on the development trends and growth points of biomanufacturing [10]. - The second and third days will feature a macro forum on biomanufacturing, specialized sub-forums on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [14]. - A special session for showcasing scientific achievements and project matchmaking will also be held, inviting innovative projects from the biomanufacturing field [15].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, discussing innovative technologies and products that can sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by Ningbo Meisai Bioengineering Co., Ltd. [2]. - Supporting organizations include the Chinese Society of Biotechnology's Biobased Materials Committee and various local industry alliances [2]. Group 3: Highlights of the Conference - The conference will feature forums and closed-door activities to gain insights into the development trends of biomanufacturing and explore new products, technologies, and collaborations [5]. - There will be over 100 financing project roadshows to discover new cooperation opportunities [5]. - Key players from leading enterprises, top universities, investment institutions, and industry stakeholders will gather to discuss advancements in the field [5]. Group 4: Agenda and Activities - The first day will include a closed-door seminar focusing on the development trends and growth points of biomanufacturing [10]. - The second and third days will feature a macro forum on biomanufacturing, specialized sub-forums on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [14]. - The conference will also host a technology achievement showcase to promote innovative results and projects in the biomanufacturing sector [15].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan and identify innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detai Zhongyan Information Technology Co., Ltd. (DT New Materials) and co-organized by Ningbo Meisai Biological Engineering Co., Ltd. [2]. Group 3: Highlights of the Conference - The conference will feature forums and closed-door activities to gain insights into the development trends of biomanufacturing during the 14th Five-Year Plan, exploring new products, technologies, and collaborations [4]. - There will be over 100 financing project roadshows to discover new cooperation opportunities [4]. - Key industry leaders, top universities, and capital from industrial parks will gather to discuss advancements in the biomanufacturing sector [4]. Group 4: Agenda and Special Activities - The first day will include a closed-door seminar focusing on the development trends and growth points of biomanufacturing, inviting 30 industry leaders and experts for in-depth discussions [7]. - The second and third days will feature a macro forum on biomanufacturing, covering the development trends and progress of policies related to the industry [10]. Group 5: Specialized Forums - The conference will host specialized forums on various topics, including green chemicals and new materials, AI in biomanufacturing, future food and agriculture, and beauty raw materials [11]. - Each forum will address specific themes such as the development of bio-based chemicals, green manufacturing technologies, and the application of AI in biomanufacturing processes [11].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan period, highlighting innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizers and Highlights - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by Ningbo Meisai Biological Engineering Co., Ltd. [2]. - Key highlights include forums on biomanufacturing trends, youth innovation sharing, project roadshows, and participation from leading enterprises, top universities, and investment institutions [4]. Group 3: Agenda and Special Activities - The first day features a closed-door high-level seminar focusing on the development trends and growth points of biomanufacturing, with 30 industry leaders and experts invited [7]. - The second and third days will include a macro forum on biomanufacturing, covering the overall trends and progress in the industry [10]. Group 4: Specialized Forums - Specialized forums will cover topics such as green chemicals and new materials, AI in biomanufacturing, future food and agriculture, and beauty raw materials [11]. - The forums will discuss various aspects of biomanufacturing, including the development of bio-based chemicals, green manufacturing technologies, and the application of AI in industrial processes [11]. Group 5: Project Roadshows and Talent Engagement - The conference will feature project roadshows aimed at connecting head parks and investment institutions with innovative biomanufacturing projects [10]. - A youth forum will be held to discover potential teams and technologies in biomanufacturing, providing a platform for efficient talent and collaboration exchanges [10].