Core Viewpoint - Kangzhe Pharmaceutical has successfully completed a secondary listing on the Singapore Exchange, marking its expansion into international capital markets after its initial public offering on the Hong Kong Stock Exchange in September 2010 [1] Group 1: Company Background - Kangzhe Pharmaceutical was established in 1995, initially focusing on contract sales organization (CSO) and marketing foreign and domestic pharmaceuticals [3] - The company transitioned from pure agency operations to self-operated products after acquiring full control of Ganfu Le in 2013 [3] - Kangzhe's business currently spans four major areas: cardiovascular, digestive, dermatology/aesthetic medicine, and ophthalmology [3] Group 2: Recent Developments - In April 2024, Kangzhe Pharmaceutical spun off its dermatology business, Demai Pharmaceutical, for independent listing [1][4] - The decision to list in Singapore is part of the company's strategy to enhance its presence in Southeast Asia and create more opportunities for international business development and potential financing needs [4] Group 3: Financial Performance - Kangzhe Pharmaceutical has experienced a decline in revenue for two consecutive years, with revenues of 6.8 billion, 8.5 billion, 9.24 billion, 7.76 billion, and 7.4 billion from 2020 to 2024 [6] - Net profits during the same period were 2.5 billion, 3 billion, 3.2 billion, 2.4 billion, and 1.6 billion, with a significant 32% year-on-year decline in 2024 [6] - The company's cash flow from operations dropped nearly 50% to 1.269 billion in 2024, indicating deteriorating operational quality [7] Group 4: Market Challenges - The decline in performance is attributed to the impact of centralized procurement, with major products like Dailixin, Yousif, and Bo Yiding losing market share, resulting in a nearly 30% revenue drop to 2.691 billion [7] - The company is facing increased competition in the dermatology sector, and Demai Pharmaceutical has reported cumulative losses of 165 million from 2022 to 2024 [8] - Despite the challenges, Kangzhe is accelerating the commercialization of its innovative drug, Lurcobatin Cream, expected to launch in the second half of 2025, targeting a market with over 22 million patients in China [8]

Group 1 - The core viewpoint of the article is that Kangzheng Pharmaceutical (00867.HK) has announced a secondary listing on the Singapore Exchange, which aims to enhance its business presence in Southeast Asia and tap into the mature investor market in Singapore [1] - The company emphasizes that Southeast Asia, with a population of nearly 700 million, is experiencing rising pharmaceutical demand due to economic growth, an expanding middle class, aging populations, and an increase in non-communicable diseases [1] - Kangzheng Pharmaceutical has established Singapore as its regional headquarters for Southeast Asia and the Middle East [1] Group 2 - Kangzheng Pharmaceutical was listed in Hong Kong on September 28, 2010, and focuses on specialized fields such as cardiovascular, central nervous system, digestive, and ophthalmology [1] - The company currently has five innovative drugs in the commercialization stage, including "Meitai Tong" for psoriasis and "Laifulan" for methylene blue enteric-coated sustained-release tablets, along with three drugs entering national procurement [1] - As of the latest trading session, Kangzheng Pharmaceutical's stock price was HK$12.94, with a total market capitalization of HK$31.567 billion [2]

Summary of 康哲药业 Conference Call Company Overview - 康哲药业 is undergoing a strategic transformation from original research drugs to innovative drugs, driven by both collaborative development and independent research. The company has received approval for 5 innovative drugs covering 6 indications and is actively expanding internationally, including a secondary listing in Singapore without involving financing or equity dilution [2][4]. Key Business Segments - The company operates four main business segments: - Cardiovascular and Digestive Health: Stabilized after the impact of the National Volume-Based Procurement (VBP) - Ophthalmology: Strong profitability - Skin Health: 德美医药 is set for a spin-off listing - International Business: Focused on Southeast Asia, expected to contribute to future growth [2][5]. Financial Performance - The core products' revenue has declined due to VBP, with projected revenue of 2.6 billion yuan for three core products in 2024. However, the impact of centralized procurement is expected to be cleared, leading to a phase of rapid growth as innovative drugs are approved [2][7]. - The company’s key product portfolio includes: - Existing national procurement products (波依定, 黛力新, 优思弗) expected to contribute 2.6 billion yuan in 2024 - Exclusive and brand drugs anticipated to maintain around 10% growth [8]. Innovative Product Pipeline - 康哲药业 has nearly 20 self-researched projects, with 5-6 in clinical development. Key upcoming products include: - Y3 injection for stroke treatment, expected to exceed 3 billion yuan in sales - ABP671 for hyperuricemia, with NDA submission expected in mid-2025 - 德西度司他片 for chronic kidney disease anemia, expected to be approved this year [3][10][12][13]. Impact of VBP - The company faced significant impacts from VBP, with core products previously accounting for over 50% of sales. The sales retention rate post-VBP was around 50% [6][7]. Spin-off of 德美医药 - The spin-off of 德美医药 is expected to be completed by the end of 2025, which will not significantly affect 康哲药业's overall financial status but will help improve its valuation. 康哲 will distribute 90.8% of 德美 shares to shareholders [3][15]. Market Expansion and Internationalization - 康哲药业 is expanding into Southeast Asia, establishing a regional headquarters in Singapore and planning a secondary listing. This move aims to explore new growth avenues without limiting business development [20][21]. R&D and Sales Expenses - In 2025, 康哲's R&D and sales expenses are expected to rise due to high costs associated with marketing and brand building for newly launched innovative drugs. Profit growth is anticipated to lag behind revenue growth this year, but significant profit increases are expected starting in 2026 as 德美 is no longer consolidated [22][23]. Conclusion - 康哲药业 is positioned for growth through its innovative drug pipeline and international expansion, despite facing challenges from VBP. The upcoming spin-off of 德美医药 and the focus on Southeast Asian markets are strategic moves to enhance overall company valuation and market presence.

Core Viewpoint - Kangzheng Pharmaceutical (00867.HK) plans to spin off its skin health business, Demy Pharmaceutical, for a "listing by introduction" on the Hong Kong Stock Exchange, marking it as the first "zero fundraising" IPO case in 2025 [2][5][18] Company Overview - Kangzheng Pharmaceutical has faced declining performance, with revenue dropping from 91.5 billion RMB in 2022 to 80.13 billion RMB in 2023, and further down to 74.69 billion RMB in 2024, representing a year-on-year decline of 12.4% and 6.7% respectively [6][7] - The company experienced a significant drop in net profit, from 23.84 billion RMB in 2023 to 16.13 billion RMB in 2024, a decrease of 27.2% [7] - The decline in performance is attributed to the failure of key products to win bids in national procurement, leading to a loss of market share and revenue [7][8] Demy Pharmaceutical Financials - Demy Pharmaceutical's revenue grew from 384 million RMB in 2022 to 618 million RMB in 2024, but it also reported increasing losses, from 55.17 million RMB in 2022 to 105.63 million RMB in 2024 [8][9] - The company's cost structure is heavily skewed towards sales expenses, which consumed 99% of its gross profit in 2024, leading to a net loss of 106 million RMB [10][12] - Demy Pharmaceutical's research and development expenditure remains low compared to its sales expenses, with a research expenditure rate of only 4% [10][12] Strategic Implications - The spin-off is seen as a strategic move to alleviate financial pressure on Kangzheng Pharmaceutical while allowing Demy Pharmaceutical to seek independent funding and partnerships [18] - The choice of "listing by introduction" allows for a quicker and less costly process, avoiding the dilution of shares and the complexities of traditional IPOs [17][18] - However, Demy Pharmaceutical will still face scrutiny regarding its ongoing losses and the sustainability of its business model post-spin-off [13][15] Market Context - The move reflects a broader trend among Chinese pharmaceutical companies seeking to adapt to the pressures of national procurement policies and increasing competition in the industry [17] - Since 2020, over 20 pharmaceutical companies have pursued similar spin-offs to focus on high-growth areas like medical aesthetics and consumer healthcare [17]

Core Viewpoint - Kangzheng Pharmaceutical is planning to spin off its subsidiary, Demai Pharmaceutical, which focuses on skin health, for independent listing on the Hong Kong Stock Exchange. This move raises questions about whether it is a strategic decision or an attempt to offload a loss-making entity [1][4]. Group 1: Spin-off Details - The spin-off will involve a distribution of 90.8% of Demai's shares to existing shareholders, with no new stock issuance for financing. This allows shareholders to directly hold shares of Demai and benefit from independent valuation premiums [1][2]. - Demai Pharmaceutical has shown revenue growth from 384 million yuan in 2022 to 618 million yuan in 2024, but its losses have also increased from 55.17 million yuan to 106 million yuan during the same period [2][3]. Group 2: Financial Performance - Demai's gross margin for prescription drugs is projected to decline from 76.6% in 2023 to 61.7% in 2024, contributing to an overall gross margin drop from 76.9% to 63.5% [2][3]. - The company's sales expense ratio has risen from 57.7% to 62.9%, with sales expenses reaching 388 million yuan in 2024, nearly matching its gross profit [2][3]. Group 3: Strategic Context - Kangzheng Pharmaceutical is facing significant performance pressure, with a revenue decline of 6.8% to 7.469 billion yuan and a net profit drop of 32.3% to 1.613 billion yuan in 2024. The decline is attributed to the impact of national procurement policies on key products [4][5]. - The spin-off aims to achieve three objectives: shedding the loss-making skin business, allowing Demai to raise capital independently, and enhancing the overall market valuation of the group by focusing on higher-margin areas [4][5]. Group 4: Market Landscape - The skin health market is projected to grow significantly, with an estimated market size of 254.9 billion yuan by 2035 and a compound annual growth rate exceeding 15% [4]. - However, Demai faces intense competition from stronger players in the skin health sector, and its reliance on generic products and high sales expenses raises concerns about sustainability [5].