水凝胶

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Cell子刊:顾晓松/吴俊华/江春平团队开发溶瘤病毒水凝胶系统,防止肿瘤复发
生物世界· 2025-10-13 04:08
撰文丨王聪 编辑丨王多鱼 排版丨水成文 肿瘤 是威胁人类健康和生命的重大疾病。对于有机会进行手术的患者来说,切除肿瘤病灶通常是首选。然而,对于已接受手术的患者而言,术后复发 (包括原位 复发和转移性复发) 是需要解决的最大挑战之一。此外,复发时间不确定,有些转移性复发可能在手术后数年甚至数十年才出现。伤口愈合过程及相关的炎症也 可能导致术后肿瘤复发。 目前,临床上常采用化疗和放疗来控制术后复发。然而,在某些情况下,这些方法往往具有较强的毒副作用。因此,迫切需要安全有效的治疗方法来控制术后肿 瘤复发。 2025 年 10 月 3 日 , 南京鼓楼医院 (南京大学医学院附属鼓楼医院) 顾晓松 院士、 吴俊华 教授、 江春平 教授等在 Cell 子刊 Cell Reports Medicine 上发 表了题为: In situ extended immune activation instantly after tumor resection by oncolytic virus controls postoperative tumor recurrence 的研究论文。 该研究构建了一种能够持续释放溶瘤病毒的稳定 ...
最新水凝胶顶刊论文盘点(30篇)!谢续明/吴子良/张拥军/贺超良等确认出席2025先进凝胶论坛
DT新材料· 2025-10-12 16:05
我们梳理了Nature、Science、Nature Communications、Science Communications、Advanced Functional Materials、 Angew、JACS和Advanced Materials等期刊上2025年以来发表的水凝胶部分论文,旨在帮助读者快速了解学界最新动态和发展脉络。 论文主题 : 具有卓越黏着性能的水凝胶 期刊 名称 : Nature 通讯 作者 : 龚剑萍、范海龙、李伟 发表时间 : 20 25 / 08 / 06 亮点工作 :依托大规模蛋白质序列数据库,成功开发出一款 具有卓越黏着性能的水凝胶 ,该水凝胶展现出优异的黏合性能,不仅能牢固黏附无机材料、 塑胶、金属等各类基材,还可在淡水或海水环境下保持稳定黏性,不受水环境干扰。更具价值的是,小鼠皮下植入实验的结果明确证实了其良好的生物相 容性。 https://doi.org/10.1038/s41586-025-09269-4 论文主题 : -115-143 ℃极端温度耐受水凝胶 期刊 名称 : Science 通讯 作者 : 罗自生、李铁风、杨栩旭 发表时间 : 20 25 / 02 ...
近百场专家报告,第四届先进凝胶论坛议程发布!
DT新材料· 2025-09-22 16:05
Core Viewpoint - The "4th Advanced Gel Materials and Industrial Applications Forum" will be held from October 21-23, 2025, in Suzhou, focusing on "Innovation-driven, Industry Integration" to create a collaborative platform for government, industry, academia, research, application, and investment [2]. Organizers and Participants - The forum is organized by the Suzhou Institute of Nano-tech and Nano-bionics, Jiangsu Advanced Gel Materials Engineering Research Center, DT New Materials, and Suzhou Nano Technology Development Co., Ltd. [3] - Honorary Chairman: Li Qingwen, Researcher at the Suzhou Institute of Nano-tech and Nano-bionics [3]. - Executive Chairmen: Zhang Xue Tong and Yan Feng, both researchers at the Suzhou Institute of Nano-tech and Nano-bionics and Suzhou University respectively [3]. Agenda Overview - The forum will include a general assembly and keynote speeches on October 22, with various presentations scheduled throughout the day [4][5]. - The agenda features a series of presentations by prominent professors from various universities, covering topics such as high-strength hydrogels, soft robotics, and bio-inspired materials [4][5][6]. Youth Scientist Forum - A special Youth Scientist Forum will take place on October 22, 2025, allowing young scientists to present their research in a structured format, fostering discussion and feedback from experts [12]. - Participants will present for 10 minutes followed by a 5-minute Q&A session, with awards presented during the forum's dinner [12]. Registration and Participation - Registration fees are set at 2600 RMB for regular attendees and 1400 RMB for student representatives, with specific payment instructions provided [19]. - Participants are encouraged to submit posters for display, with guidelines on size and submission process outlined [17]. Previous Forums - The article highlights the successful hosting of previous forums in 2021, 2023, and 2024, indicating a strong foundation and ongoing interest in the field of advanced gel materials [26].
30篇!2025年最新水凝胶顶刊论文盘点
DT新材料· 2025-09-13 16:05
Core Viewpoint - The articles summarize recent advancements in hydrogel research published in various prestigious journals, highlighting innovative applications and properties of hydrogels that could lead to significant industrial and medical advancements [2][3][4]. Group 1: Hydrogel Innovations - A hydrogel with exceptional adhesion properties was developed, demonstrating strong bonding to various substrates and maintaining stability in freshwater and seawater environments, confirmed by biocompatibility tests in mice [2]. - A dual-network hydrogel was created that remains flexible across extreme temperatures from -115 °C to 143 °C, significantly expanding the functional range of hydrogels [2]. - Chiral peptide hydrogels were synthesized for use in cancer vaccines, showing the ability to modulate local immune environments and induce distinct anti-tumor immune responses [3]. Group 2: Performance Enhancements - A novel nanofiber interwoven gel membrane was developed, exhibiting outstanding CO₂ permeability (2110 GPU) and selectivity (CO₂/N₂ of 151, CO₂/CH₄ of 47), surpassing traditional membranes [3]. - A dynamic phase-adaptive hydrogel platform was introduced, effectively repairing chronic wounds infected by drug-resistant bacteria while significantly reducing scar formation [5]. - A high-performance eutectic gel was created with superior mechanical properties, including a Young's modulus of 103.1 MPa and toughness of 86.8 MJ/m³, while maintaining flexibility at -80 °C [5]. Group 3: Advanced Applications - A thermoresponsive hydrogel was developed for post-surgical adhesion prevention, demonstrating superior effectiveness in reducing adhesion rates compared to commercial products without causing cardiac dysfunction [12]. - A smart hydrogel system was designed for the controlled release of siRNA, significantly accelerating the healing process of chronic diabetic wounds [18]. - A new ice-template technique was utilized to create a hydrogel with circumferential fiber structures, showcasing excellent tensile performance and compressibility [19].
研判2025!中国水凝胶行业产业链、市场规模及重点企业分析:作为高亲水性三维网络聚合物,成为生物医药等多领域关键材料[图]
Chan Ye Xin Xi Wang· 2025-09-04 01:30
Industry Overview - Hydrogel is a highly hydrophilic three-dimensional polymer network known for its excellent water absorption, biocompatibility, and stimulus-responsive properties, making it a key material in various fields such as biomedicine, industrial environmental protection, and daily chemical consumption [1][11] - The market size of China's hydrogel industry is projected to reach 6.95 billion yuan in 2024, with a year-on-year growth of 5.62%, driven by increasing demand in medical applications and the beauty and skincare sector [1][11] Market Size - The hydrogel industry is experiencing growth due to its wide applications, particularly in medical products like hydrogel dressings and tissue engineering scaffolds, as well as in beauty products such as moisturizing and repairing hydrogel masks [1][11] Key Companies - Major players in the Chinese hydrogel market include international giants like 3M Company, Cardinal Health, Inc., and Coloplast Group, which dominate the high-end market due to their technological advantages and brand influence [11] - Domestic companies such as Changchun Jiyuan Biotechnology Co., Ltd. and Zhuhai Guojia New Materials Co., Ltd. are emerging, leveraging technological innovation and market expansion to gain a foothold in the mid-to-high-end market [11][13][14] Industry Chain - The upstream of the hydrogel industry chain includes natural and synthetic polymers, crosslinking agents, and production equipment, while the midstream focuses on hydrogel manufacturing [6][7] - The downstream applications span biomedicine, agriculture, environmental protection, daily chemicals, and industrial uses [7][8] Development Trends - Technological innovation is accelerating, leading to product upgrades, with a focus on smart responsive hydrogels that can react to external stimuli for precise drug delivery and environmental control [14] - The application fields of hydrogels are diversifying, extending beyond traditional sectors to include tissue engineering, regenerative medicine, and smart medical devices [15] - Emphasis on green production and sustainable development is becoming crucial, with a shift towards environmentally friendly materials and production processes [16]
Cell子刊:浙江大学贺永/吴梦婕/尹俊团队开发生物水凝胶电池,用于组织再生及心脏起搏
生物世界· 2025-09-02 04:03
Core Viewpoint - The article discusses the development of a biodegradable biohydrogel battery that addresses the limitations of traditional batteries in biomedical applications, emphasizing the need for high-performance energy sources that are compatible with biological systems [4][7]. Group 1: Biohydrogel Battery Development - Researchers from Zhejiang University have designed a biodegradable biohydrogel battery using light polymerization and 3D printing techniques, showcasing excellent mechanical properties and biocompatibility [4]. - The biohydrogel battery operates at a voltage of 1.5 V, providing a current range of 0.001-6 mA, which supports tissue regeneration and cardiac pacing applications [4][8]. Group 2: Hydrogel Characteristics and Applications - Hydrogels, as three-dimensional cross-linked polymer networks, exhibit properties similar to biological tissues, making them suitable for various biomedical applications such as drug delivery and tissue engineering [6]. - The integration of gallium-based liquid metals with hydrogels enhances their conductivity and mechanical performance, promoting their use in flexible bioelectronic devices [6]. Group 3: Challenges and Solutions in Energy Systems - Traditional batteries face significant limitations in biomedical applications due to poor biocompatibility, non-degradability, and rigidity, which can harm surrounding tissues [7]. - The development of a flexible, biodegradable power source using conductive ion hydrogels and InGa3-Cu nanoparticles addresses these challenges, maintaining stable current during degradation [7]. Group 4: Performance Metrics - The biohydrogel battery features a high printing precision of 50 micrometers, with tensile strain and compression rates of 200% and 95%, respectively, aligning with the mechanical properties of biological tissues [8]. - It operates in dual current modes, facilitating microcurrent for tissue regeneration and high current for effective cardiac pacing [8].
报名!外泌体 · 水凝胶:促进皮肤损伤修复的材料新路径
思宇MedTech· 2025-07-08 09:42
Core Viewpoint - The article highlights the ongoing developments in the field of skin repair and aesthetic medicine, particularly focusing on the integration of exosomes and hydrogels as innovative solutions for skin tissue regeneration and precise repair [1][6]. Group 1: Event Overview - The event titled "2025 Third China Plastic Surgery Innovation and Transformation Competition" is currently open for registration, featuring various sessions on medical aesthetics and innovation in medical devices [1]. - The event will include a special sharing session by Dr. Chen Junge from Beihang University, focusing on the basic mechanisms of skin injury repair and material system design [2][6]. - The event is organized by the Ba Da Chu Plastic Surgery Medical Concept Verification Center, which is the first professional platform in China dedicated to the transformation of plastic surgery technology achievements [5]. Group 2: Key Topics and Discussions - The agenda includes a presentation on "Exosomes and Smart Hydrogels: From Delivery Systems to Skin Regeneration," emphasizing the role of exosomes in skin regeneration and the design logic of hydrogels as delivery systems [4][6]. - Discussions will cover the pathways and technical challenges of exosomes in skin regeneration, the design keys and application differences of hydrogels in delivery systems, and the differentiation of product paths for skin medical and aesthetic applications [10]. - The event aims to explore how basic research can transition into industrial transformation, identifying key links and the layout logic of entrepreneurial teams in the skin repair sector [10].
【会议通知】第四届先进凝胶材料及产业应用论坛
DT新材料· 2025-07-01 14:39
Group 1 - The article highlights the significance of gel materials, which possess multifunctional physicochemical properties and can form various advanced gel materials such as hydrogels, organic gels, ionic gels, oil gels, and aerogels, widely researched and applied in fields like biology, medicine, chemistry, physics, and engineering [2] - The "4th Advanced Gel Materials and Industrial Applications Forum" is scheduled to be held from October 21-23, 2025, in Suzhou, focusing on the theme "Innovation-driven, Industry Integration" to create a collaborative platform for government, industry, academia, research, and investment [2][3] - The forum aims to address key scientific issues, bottleneck technologies, and engineering applications related to gel materials, promoting cross-disciplinary and international collaboration to drive innovation in the gel materials industry [2] Group 2 - The event will take place at the Suzhou International Expo Center, organized by the Suzhou Institute of Nano-tech and Nano-bionics, Jiangsu Advanced Gel Materials Engineering Research Center, DT New Materials, and Suzhou Nano Technology Development Co., Ltd. [3] - The agenda includes a registration period, opening ceremony, keynote speeches, and parallel forums, with specific timings outlined for each day of the event [4] - Topics of discussion will include but are not limited to hydrogels, organic gels, ionic gels, oil gels, and aerogels [7]
【第一轮通知】第四届先进凝胶材料及产业应用论坛 10.21-23 苏州
DT新材料· 2025-06-09 15:33
大会信息 (持续增加中) 会议时间: 2025年10月21-23日(周二-周四) 会议场地: 江苏省苏州国际博览中心 主办单位: 中国科学院苏州纳米技术与纳米仿生研究所 江苏省先进凝胶材料工程研究中心 DT新材料 苏州纳米科技发展有限公司 承办单位: 宁波德泰中研信息科技有限公司 名誉主席: 李清文 ,中国科学院苏州纳米技术与仿生研究所研究员 执行主席: 张学同 ,中国科学院苏州纳米技术与仿生研究所研究员 大会背景 凝胶作为一种具有多功能理化特性的胶体聚合物材料,可以在其三维网络结构中结合大量的流体相 而形成 水凝胶、有机凝胶、离子凝胶、油凝胶或气凝胶 等先进凝胶材料,在生物、医学、化学、 物理和工程等领域得到广泛且深入地研究与应用。在国家对新材料高度重视与碳中和战略驱动,以 及生物技术、新能源汽车、新能源、节能环保等新兴产业对于新材料的更高需求下,凝胶产业将迎 来广阔的发展前景。 在前三届成功举办的基础上, "第四届先进凝胶材料及产业应用论坛" 将于2025年 10月21-23日 在 苏州 举办,论坛以 "创新驱动,产业融合" 为主题,旨在搭建"政产学研用资"六位一体的交流合作 平台。论坛将聚焦凝胶材料关键 ...