注射用HDM2017
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10月10日晚间重要公告一览
Xi Niu Cai Jing· 2025-10-10 10:17
Group 1 - Jieqiang Equipment has completed the acquisition of 51% stake in Shandong Carbon Seeking, which will now be included in the company's consolidated financial statements [1] - Tonghua Dongbao's insulin injection product has received marketing approval in Myanmar for diabetes treatment [1] - New Light Optoelectronics' actual controller plans to increase shareholding by 5 to 10 million yuan within six months [2] Group 2 - Far East Holdings received contracts worth 1.769 billion yuan in September [3] - Poly Developments reported a 1.84% decrease in signed sales amount in September, totaling 20.531 billion yuan [4] - ST Nuotai expects a net profit increase of 5.62% to 13.74% for Q3 2025 [7] Group 3 - Chongqing Port's controlling shareholder plans to merge with another entity, changing the controlling shareholder to Chongqing Logistics Group [9] - New Energy Company reported a 28.21% increase in cumulative power generation from January to September [11] - Dashiang Co. announced the resignation of its chairman due to personal reasons [12] Group 4 - Liao Port Co. announced the resignation of a non-executive director due to work changes [13] - Zhongzai Resources received a government subsidy of 5.33 million yuan, accounting for 23.72% of its audited net profit for 2024 [14] - Xiaoming Co. reported a sales revenue of 66.15 million yuan from chicken products in September [15] Group 5 - Tianyi Co. signed a framework contract worth 23.50 million yuan for e-business network terminal production [16] - Jingu Co. signed a strategic cooperation agreement with Ninebot Technology for lightweight materials [18] - Tianbang Foods reported a sales revenue of 634 million yuan from commodity pigs in September [20] Group 6 - Shaanxi Energy's subsidiary received an administrative penalty for safety violations, resulting in a fine of 940,000 yuan [22] - North Bay Port reported a 9% increase in cargo throughput in September [23] - Tangrenshen reported a sales revenue of 639 million yuan from pig sales in September [24] Group 7 - Dabeinong reported a sales revenue of 541 million yuan from pig sales in September [25] - Jiukang Bio obtained four medical device registration certificates [26] - Canan Co. invested 90 million yuan in structured deposits with a bank [27] Group 8 - Zhuhai Port reported a 5.44% decrease in cargo throughput in Q3 [28] - Jinli Yongmag expects a net profit increase of 157% to 179% for the first three quarters [29] - Huamao Logistics' controlling shareholder plans to increase shareholding by 64.5 to 129 million yuan [30] Group 9 - Dongjie Intelligent signed a 50 million yuan contract for intelligent warehousing in the steel industry [31] - Sais Technology signed a cooperation framework agreement with Volcano Engine for intelligent robotics [32] - Huadong Pharmaceutical's subsidiary received approval for clinical trials of a new drug targeting advanced solid tumors [34] Group 10 - TCL Technology completed the acquisition of 80% and 100% stakes in LG Display's subsidiaries for 11.088 billion yuan [34] - Shuangliang Energy won a 419 million yuan EPC project for cooling systems [36] - Ruina Intelligent announced plans for shareholders to reduce their stakes by up to 1.18% [38] Group 11 - Baodi Mining announced plans for shareholders to reduce their stakes by up to 5.45% [40] - Xinyi Technology's shareholders set the transfer price for shares at 328 yuan each [42] - Sunshine Power submitted an application for H-share listing on the Hong Kong Stock Exchange [44] Group 12 - Qisheng Technology's controlling shareholder plans to reduce their stake by up to 3.09% [46] - Wu Ming Kangde sold 30.3 million shares of Wu Ming He Lian through block trading [48] - Qiaoyin Co. announced plans for shareholders to reduce their stakes by up to 6% [49] Group 13 - Muyuan Foods reported a sales revenue of 9.066 billion yuan from commodity pigs in September [51] - Huawang Technology's shareholders plan to reduce their stakes by up to 1.1% [53] - Huaxin Xinchuang received a project notification from Lantu Automotive for display components [54] Group 14 - China Merchants Shekou reported a signed sales amount of 16.698 billion yuan in September [55] - Shao Neng Co. received approval for an antitrust review regarding a share acquisition [57] - Pengding Holdings reported a 6.21% increase in consolidated revenue in September [58] Group 15 - Ganfeng Lithium is advancing its solid-state battery commercialization and strategic investment in the energy storage sector [59]
华东医药(000963.SZ):注射用HDM2017获得药物临床试验批准通知书
Ge Long Hui A P P· 2025-10-09 11:15
Core Viewpoint - East China Pharmaceutical (000963.SZ) announced that its wholly-owned subsidiary, Hangzhou Sino-American East Pharmaceutical Co., Ltd. (referred to as "Sino-American East"), has received the Clinical Trial Approval Notice from the National Medical Products Administration (NMPA) for the clinical trial application of HDM2017 [1] Group 1 - HDM2017 is designed to specifically target CDH17 positive tumor surface antigens through antibody-mediated internalization, allowing the ADC to enter tumor cells and release toxic payloads to exert anti-tumor effects [1] - Preclinical studies indicate that HDM2017 demonstrates good drug-like properties, safety, and efficacy [1] - HDM2017 has shown strong anti-tumor effects in efficacy models for colorectal cancer, pancreatic cancer, and gastric cancer, and has good tolerance in animal trials [1]
华东医药:由中美华东申报的注射用HDM2017临床试验申请获得批准
Mei Ri Jing Ji Xin Wen· 2025-10-09 10:44
Group 1 - The core point of the article is that Huadong Medicine's subsidiary has received approval for a clinical trial of an injectable drug, HDM2017, from the National Medical Products Administration (NMPA) [1] - As of the first half of 2025, Huadong Medicine's revenue composition is as follows: 68.23% from commercial brokerage and agency, 33.94% from pharmaceutical manufacturing, 4.57% from medical aesthetics, and 0.77% from other businesses, with inter-segment eliminations accounting for -7.5% [1] - The current market capitalization of Huadong Medicine is 73.2 billion yuan [1]
华东医药ADC创新药临床试验获FDA批准;亚宝药业终止一药品研发
Mei Ri Jing Ji Xin Wen· 2025-09-22 23:17
Group 1: Huadong Medicine - Huadong Medicine's subsidiary received FDA approval for the clinical trial of HDM2017, a new antibody-drug conjugate targeting Cadherin17 for advanced malignant solid tumors [1] Group 2: Tianjin Tasly - Tasly's subsidiary received approval for the new indication of Pu You Ke for thrombolytic treatment of acute ischemic stroke, making it the only approved recombinant human urokinase product in China [2] Group 3: Yabao Pharmaceutical - Yabao Pharmaceutical decided to terminate the clinical trial of SY-009 and fully provision for asset impairment of 55.793 million yuan, which will reduce the company's profit for 2025 [3][4] Group 4: Zhixiang Jintai - Zhixiang Jintai signed exclusive cooperation agreements with Kangzhe Pharmaceutical for the commercialization of GR2001 and GR1801 monoclonal antibodies, with expected payments totaling approximately 510 million yuan [4] Group 5: Lepu Medical - Lepu Medical entered a strategic partnership with Hanhai Information to jointly develop the medical aesthetics business, aiming to enhance sales channels and improve performance amid industry competition [5]
华东医药ADC创新药临床试验获FDA批准;亚宝药业终止一药品研发丨医药早参
Mei Ri Jing Ji Xin Wen· 2025-09-22 23:12
Group 1 - Huadong Medicine's subsidiary received FDA approval for the clinical trial of HDM2017, a new antibody-drug conjugate targeting Cadherin 17, for advanced malignant solid tumors [1] - Tianjin Pharmaceutical's subsidiary obtained approval for the new indication of Pu You Ke for thrombolytic treatment of acute ischemic stroke, making it the only approved recombinant human urokinase product in China [2] - Yabao Pharmaceutical decided to terminate the clinical trial of SY-009 and fully provision for asset impairment of 55.793 million yuan, which will reduce the company's profit for 2025 [3] Group 2 - Zhixiang Jintai signed exclusive cooperation agreements with Kangzhe Pharmaceutical for the commercialization of GR2001 and GR1801 monoclonal antibodies, with expected payments totaling approximately 510 million yuan [4] - Lepu Medical established a strategic partnership with Hanhai Information to jointly develop the medical aesthetics business, aiming to enhance sales channels and improve performance amid industry competition [5][6]
华东医药股份有限公司关于与专业投资机构共同投资设立专项医药产业投资基金暨关联交易的进展公告
Shang Hai Zheng Quan Bao· 2025-09-22 19:32
Group 1: Investment Overview - The company has established a specialized pharmaceutical industry investment fund in collaboration with professional investment institutions, aiming to enhance its industrial investment ecosystem and core competitiveness [2][5]. - The total committed capital for the fund is RMB 2 billion, with the company contributing RMB 980 million, representing a 49% stake [2][5]. - The fund is named "Hangzhou Fuguang Hongze Equity Investment Partnership (Limited Partnership)" and has completed its business registration and regulatory filing [3][4]. Group 2: Fund Progress - As of the announcement date, the fund has successfully raised the initial capital of RMB 10 million [3][4]. - The fund's operational scope includes equity investment and venture capital, specifically targeting unlisted companies [3][4]. Group 3: Impact on the Company - The fund will primarily invest in innovative drugs, medical aesthetics, health, animal protection, and other sectors aligned with the company's strategic development [5]. - This initiative is expected to improve the efficiency of the company's idle capital, reduce investment risks, and create reasonable returns for shareholders [5]. Group 4: Clinical Trial Approval - The company's wholly-owned subsidiary has received FDA approval for the clinical trial of the drug HDM2017, which targets advanced malignant solid tumors [9][10]. - HDM2017 is a novel antibody-drug conjugate developed by the subsidiary, showing promising preclinical results in treating various cancers [11][12]. - The approval marks a significant advancement in the drug's development process, enhancing the company's competitiveness in the oncology field [12].
华东医药:注射用HDM2017药品临床试验申请获美国FDA批准
Zhi Tong Cai Jing· 2025-09-22 11:29
Core Viewpoint - The company has received FDA approval for its clinical trial application for the injectable drug HDM2017, which will be used for Phase I clinical trials in the United States targeting advanced malignant solid tumors [1] Company Summary - The full subsidiary of the company, Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd., is responsible for the application that received FDA approval [1] - The approved clinical trial will focus on advanced malignant solid tumors, indicating a strategic move into the oncology market [1]
华东医药(000963.SZ):注射用HDM2017药品临床试验申请已获得美国FDA批准
Ge Long Hui A P P· 2025-09-22 11:28
Core Viewpoint - Huadong Medicine (000963.SZ) announced that its wholly-owned subsidiary, Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. (referred to as "Zhongmei Huadong"), has received notification from the U.S. Food and Drug Administration (FDA) that the clinical trial application for the injectable HDM2017 drug submitted by Zhongmei Huadong has been approved, allowing the company to conduct Phase I clinical trials in the U.S. for the indication of advanced malignant solid tumors [1]. Company Summary - Huadong Medicine's subsidiary, Zhongmei Huadong, has received FDA approval for its clinical trial application [1]. - The approved drug, HDM2017, is intended for the treatment of advanced malignant solid tumors [1].
华东医药:全资子公司获得美国FDA药物临床试验批准通知书
Mei Ri Jing Ji Xin Wen· 2025-09-22 11:23
Core Viewpoint - Huadong Medicine's subsidiary, Hangzhou Sino-American Huadong Pharmaceutical Co., has received FDA approval for the clinical trial of HDM2017, aimed at treating advanced malignant solid tumors [1] Group 1: Company Developments - The FDA has approved the clinical trial application for HDM2017, allowing the company to conduct Phase I trials in the U.S. [1] - As of the first half of 2025, Huadong Medicine's revenue composition is as follows: 68.23% from commercial brokerage and agency, 33.94% from pharmaceutical manufacturing, 4.57% from medical aesthetics, and 0.77% from other businesses, with inter-segment eliminations at -7.5% [1] - The current market capitalization of Huadong Medicine is 73.7 billion yuan [1]