一诺生物的故事始于2015年。公司实控人、河南濮阳籍企业家刘占杰带领团队，将目光投向了一种看似普通的农业废弃物—玉米芯。 通过一系列生物与化学转化技术，玉米芯被转化为高附加值的生物基平台化合物糠醛，进而衍生出 糠醇、2-甲基四氢呋喃、1,2-戊二醇、2-甲基呋 喃、四氢糠醇等系列 产 品 。其中，糠醇作为传统优势产品，近年营收占比超过50%；而2-甲基四氢呋喃和1,2-戊二醇则成为公司当前毛利的主要贡 献者。 尤其值得关注的是，公司的 生物基1,2-戊二醇产品 在2024年荣获中国石油和化学工业联合会评定的 "化工新材料年度创新产品" 称号 。这项荣誉凸显 了其技术的创新性与产业价值。该产品作为一种多功能原料，广泛应用于农药杀菌剂、化妆品保湿剂及医药领域。 "国家级＋省级"双冠军 一诺生物官网显示，在山东省工业和信息化厅公布的 第九批山东省制造业单项冠军企业 拟认定名单中，公司核心产品" 2-甲基四氢呋喃（2-MeTHF） "成功入选，这标志着继糠醇荣获国家级制造业单项冠军之后，公司在生物质化工领域再度获得权威认可，实现了"国家级＋省级"双冠军的联动格局。 此外，一诺生物核心产 品 2-甲基四氢呋喃 入 选 ...

关键词 | 新叶奖 |聚维元创| 生物基丁二胺、全生物基包材及底座、秸秆源葡萄糖 「 新叶奖 」 是 专注于生物基领域创新的全球化、综合性奖项，致力于挖掘、展示、表彰生物基行业的好产品、好企业， 被誉为 生物基行业的"奥 斯卡" 。第四届新叶奖将于 第十一届生物基大会暨展览 （Bio-based 2026）举行颁奖典礼。 ↓↓↓ 专注于秸秆基生物制造的高科技企业 苏州聚维元创生物科技有限公司 携生物基丁二胺、全生物基包材及底座、秸秆源葡萄糖三大产品 竞选第四届新叶奖 " 创新材料奖 "、" 创新应用奖 "与" 最具商业价值奖 " 并已入驻DT新材料全球生物基和生物制造产业服务平台-新品库 https://www.bio-basedlink.net/index/Brand （欢迎点击文末原文链接，搜索聚维元创） 四大奖项 ： 创新材料奖、创新应用奖、最具商业价值奖、创新行业解决方案奖 。 报名/提交资料截止时间 ：2026年3月13日 【 元 △ / 元 | 二 | 7 ST 1 竞选企业 √ 生物基 1,4-丁二胺 以秸秆为原料生物 合成的耐高温尼龙 核心单体,实现绿 色、低成本国产化 突破国外技术垄 断。 ...

Core Viewpoint - The bio-based 1,3-propanediol (PDO) industry in China is transitioning from "technology validation" to "scale production" by 2025, driven by the demand for green transformation in downstream markets such as textiles and cosmetics [2]. Group 1: PDO Production Capacity and Technological Advances - By 2025, multiple companies are accelerating the construction of large-scale production bases for bio-based PDO, with significant investments and technological breakthroughs [4][5]. - Companies like Qingda Zhixing and Heng Carbon Technology have successfully developed fermentation methods for PDO production, breaking the technological monopoly of foreign firms [5][6]. - Heng Carbon Technology has established a unique production base with an annual capacity of 15,000 tons, utilizing a revolutionary "three non-four no" technology that is highly environmentally friendly [6][7]. Group 2: Market Expansion and Applications - PDO is widely applicable in various industries, including polyester, cosmetics, polyurethane, pharmaceuticals, and coatings [10]. - The global bio-based PTT market, which utilizes PDO as a core monomer, is projected to grow from approximately 3.4 billion yuan in 2023 to 8.3 billion yuan by 2030, with a compound annual growth rate of 13.1% [13]. - Companies are forming strategic partnerships to create integrated industrial bases that enhance competitiveness in the bio-based PTT market [13][14]. Group 3: Emerging Companies and Innovations - New companies are emerging with innovative production techniques, such as Shandong Xiangchi Jianyuan Biotechnology, which is implementing advanced fermentation methods to enhance production efficiency [9]. - Zhongke Baiyijin has successfully produced bio-based PDO with a purity of 99.9% using biomass as a raw material [9]. - The industry is witnessing a structural expansion in downstream markets, particularly in textiles and cosmetics, benefiting from reduced raw material costs and increased production capacity [14].

Core Viewpoint - The article discusses the significant transition of China's bio-based 1,3-propanediol (PDO) industry from "technology validation" to "scale production" by 2025, highlighting the increasing demand for green transformation in downstream markets such as textiles and cosmetics [4][6]. Group 1: Industry Development - By 2025, multiple companies are advancing the construction of large-scale production bases for bio-based PDO, with the recent environmental assessment announcement for Yifeng Jiatai's 30,000 tons/year PDO project marking the fourth such project in China [4][6]. - Domestic companies like Dongfang Shenghong, Qingda Zhixing, and Juhua Co. have increased R&D investments to achieve bio-fermentation production of PDO, breaking the technological monopoly of foreign firms [7][8]. Group 2: Technological Innovations - Qingda Zhixing is noted for mastering both glycerol and sugar fermentation technologies for PDO production, with established production bases in Shandong and Shanxi [8]. - Hengcarbon Technology has developed a revolutionary third-generation PDO production technology with minimal environmental impact, achieving a production capacity of 15,000 tons/year [8]. - The next phase of bio-based PDO production will focus on "multi-raw material" technology to reduce cost risks [9]. Group 3: Market Expansion - PDO is widely applicable in various industries, including polyester, cosmetics, polyurethane, pharmaceuticals, and coatings [11]. - The global bio-based PTT market, which utilizes PDO as a core monomer, is projected to grow from approximately 3.4 billion yuan in 2023 to 8.3 billion yuan by 2030, with a compound annual growth rate of 13.1% [14]. - Companies like Qingda Zhixing and Dongfang Shenghong are forming strategic partnerships to create integrated industrial bases for bio-based materials, ensuring competitive advantages in the market [15][16].

Core Viewpoint - The article discusses the recent re-approval of two significant projects by Shandong Tianyi Hongda Biotechnology Co., Ltd., focusing on the production of bio-based succinic acid and 1,4-butanediol, highlighting their investment details and potential applications in various industries [2][3][4][5]. Investment and Project Details - The bio-based succinic acid project has a total investment of 50.483 million yuan, with 1.5 million yuan allocated for environmental protection, accounting for 2.97% of the total investment. The project covers an area of 223.22 acres (148,814.08 m²), with the specific project area being 152.22 acres (101,480.51 m²) [3]. - The 1,4-butanediol production project has a total investment of 19.703 million yuan, with 1.5 million yuan for environmental protection, which constitutes 7.61% of the total investment. This project occupies 71 acres (47,333.57 m²) and is located in the Changyi Chemical Industry Park in Weifang City, Shandong Province [4]. Applications of Products - Succinic acid can be utilized in the production of plastics, resins, and rubber, serving as a plasticizer, modifier, coating agent, and adhesive. It also acts as an intermediate in pharmaceuticals for synthesizing certain drugs and can be used as a food additive, flavoring agent, preservative, and acidulant [3]. Company Overview - Shandong Tianyi Hongda Biotechnology Co., Ltd. was established on March 21, 2024, with a registered capital of 10 million yuan. The company is located in the Changyi Chemical Industry Park and focuses on bioengineering and bio-based chemicals, integrating research and development, production, and sales [5].

Core Viewpoint - The report highlights that Wanhua Chemical's equipment upgrades will enhance profitability and accelerate the conversion of self-developed technologies into results [1]. Group 1: Recent Developments - The first ethylene plant's upgrade is expected to significantly reduce production costs, with the company focusing on optimizing key production processes to achieve extreme cost efficiency [2]. - The second ethylene plant, with a capacity of 1.2 million tons per year, successfully commenced operations in the first half of 2025, utilizing a mixed feed of ethane and naphtha [2]. - Kuwait Petrochemical Industries Company (PIC) has increased its investment in Wanhua Chemical (Yantai) Petrochemical Co., Ltd. by $638 million, acquiring a 25% stake [2]. Group 2: Project Approvals - Wanhua Chemical's MDI capacity expansion project in Fujian has been approved, aiming to upgrade the existing 800,000 tons per year MDI project to 1.5 million tons per year by modifying various production units [3]. - By the end of 2024, the company is projected to have an MDI capacity of 3.8 million tons per year, with the Fujian project expected to add 700,000 tons per year, reaching a total global capacity of 4.5 million tons per year by the second quarter of 2026 [3]. Group 3: Technology and Product Development - The company has successfully launched its MS unit, expanding its optical business product line, and has industrialized tert-butylamine, enhancing the specialty amine supply chain [3]. - The company has produced qualified sulfone polymers, improving its engineering plastics solutions, and has successfully introduced bio-based 1,3-butanediol to cosmetic clients [3]. - Ongoing R&D investments in battery materials have led to breakthroughs, with the fourth-generation lithium iron phosphate achieving mass production and the fifth generation reaching initial production [3]. - The company is committed to a differentiated product strategy, developing high-value products such as POE, polyolefins, nylon 12, and modified materials to expand into niche markets [3]. Group 4: Profit Forecast - The company forecasts net profits attributable to shareholders of 13.495 billion, 16.350 billion, and 18.100 billion yuan for the years 2025 to 2027, respectively [4]. - Based on comparable company valuations, a target price of 73.08 yuan is set, with a "buy" rating assigned for the initial coverage [4].

Core Viewpoint - The article emphasizes the development of the high-end chemical industry in Weifang, Shandong, focusing on the integration of industrial chains, digital transformation, and green development to enhance competitiveness and sustainability [2][3][5][6]. Group 1: Industrial Chain Development - Weifang is a significant chemical industry base in China, with the high-end chemical sector projected to achieve a revenue of 397 billion yuan in 2024, accounting for one-seventh of Shandong's total [3]. - The city has established a robust industrial cluster, including petrochemical, coal chemical, salt chemical, and fine chemical industries, which enhances overall competitiveness and supports regional economic growth [3][4]. - Weifang hosts seven national-level manufacturing champions, with over 30 products holding the highest global market share, showcasing its critical position in both national and global supply chains [3]. Group 2: Digital Transformation - Digital transformation is identified as a key driver for improving quality and efficiency in the chemical industry, reshaping the development landscape in Weifang [5]. - Strategic collaborations, such as the partnership between Alliance Chemical and the COSMOPlat industrial internet platform, aim to establish leading smart factories in the chemical sector [5]. - Companies like New and Achieve are exploring new paths for digital transformation, enhancing production efficiency and quality through automation and smart technologies [5]. Group 3: Green Development - The high-end chemical industry in Weifang is actively pursuing green development, integrating low-carbon practices throughout production processes [6][7]. - Companies are innovating by using renewable resources and advanced recycling technologies to minimize carbon footprints and energy consumption [6][7]. - The successful implementation of green technologies demonstrates that the industry's economic and environmental goals can be mutually reinforcing, contributing to a sustainable future [7].

Investment Rating - The investment rating for the company is "Buy" (maintained) [1] Core Views - The company reported a significant year-on-year revenue increase of 46.54% in the first half of 2025, achieving a total revenue of 1.489 billion yuan, while the net profit attributable to shareholders decreased by 23.26% to 115 million yuan [4][5] - The second quarter of 2025 showed a revenue of 802 million yuan, reflecting a year-on-year increase of 55.61% and a quarter-on-quarter increase of 16.74% [4][5] - The increase in sales volume of main products has driven substantial revenue growth, although product price declines have compressed profit margins [5][6] - The company is focusing on high R&D investment to drive technological iteration and enhance risk resistance through flexible production [7][8] - New projects are being continuously advanced, particularly in bio-based new materials, which are expected to contribute to revenue growth [9] Summary by Sections Financial Performance - In the first half of 2025, the company achieved a revenue of 1.489 billion yuan, with a year-on-year growth of 46.54% [4] - The second quarter's revenue was 802 million yuan, with a year-on-year increase of 55.61% and a quarter-on-quarter increase of 16.74% [4] - The net profit for the first half was 115 million yuan, down 23.26% year-on-year [4] Product and Market Dynamics - The main products, amino acids and vitamins, generated revenues of 1.057 billion yuan and 80 million yuan respectively, with year-on-year changes of +42.29% and -4.87% [5] - The average market prices for key products have declined, impacting profit margins [6] R&D and Innovation - R&D expenses reached 68.67 million yuan in the first half of 2025, accounting for 4.61% of revenue, with a year-on-year increase of 8.40% [7] - The company has established an AI digital laboratory to integrate advanced technologies into production processes [7][8] Future Outlook - The company expects net profits of 266 million yuan, 372 million yuan, and 478 million yuan for 2025, 2026, and 2027 respectively, with corresponding P/E ratios of 34, 24, and 19 [10]

Investment Rating - The industry investment rating is "Overweight" [1] Core Insights - The report highlights the ongoing active research in life sciences and the global wave of biotechnology revolution, which is accelerating integration into economic and social development, providing new solutions for major challenges such as health, climate change, resource security, and food security. The National Development and Reform Commission has issued the "14th Five-Year Plan for the Development of the Bioeconomy," indicating a trillion-yuan market potential in the bioeconomy sector [3][4]. Market Performance - The synthetic biology index, composed of 58 listed companies involved in synthetic biology and related technologies, rose by 8.25% to 1845.19 during the week of August 25-29, 2025. This performance outpaced the Shanghai Composite Index by 7.41% and the ChiNext Index by 0.51% [4][19]. - The overall performance of synthetic biology stocks met expectations, with an increase of 8.25%, ranking second among various sectors [19]. Company Developments - The report mentions several significant developments in the synthetic biology sector: - The first synthetic biology project in Ordos City, with an investment of 230 million yuan, aims to produce 4,000 tons of bio-based calcium propionate annually, positioning itself as the largest producer of clean label products globally [10]. - The successful trial of the world's first bio-based 1,5-pentanediol process by Seabear, achieving over 99.5% purity, which is significant for high-end cosmetics and biomedicine [26]. - A framework cooperation agreement for a 31 billion yuan green hydrogen methanol integrated project was signed in Duolun County, aiming to produce 200,000 tons of green hydrogen and 1 million tons of green methanol annually [26]. - The successful licensing of the SRJET bio-jet fuel production technology by Sinopec's research institute to Total Energy, marking its entry into the global market [27]. Financing Trends - The report notes an acceleration in financing for synthetic biology companies, with nearly a hundred companies completing new financing rounds since the beginning of 2025. Notable financing activities include: - Nanjing Batefly completing a round of financing to develop high-performance packaging solutions [34]. - Huaxi Biological's exclusive investment from CVC Fund for the commercialization of a new generation of pre-filled syringes [36]. Research Directions - The report outlines several innovative research directions: - Zhongke Guosheng's development of a bio-based aromatic polyamide fiber using FDCA, marking a breakthrough in the bio-based materials sector [38]. - Zhengtong Technology's new biodegradable polyester, which combines the biodegradability of aliphatic polyesters with the mechanical properties of aromatic polyesters, receiving national patent authorization [39].

Core Viewpoint - The article highlights the successful trial of the world's first bio-based 1,5-pentanediol production process by the company, which utilizes a unique one-step hydrogenation method, achieving high purity and meeting international standards [2][5]. Group 1: Production Process - The company has developed a bio-based 1,5-pentanediol production technology that demonstrates significant innovation by employing a special catalyst in a one-step hydrogenation process [5]. - The industrial production of 1,5-pentanediol can follow two main technological routes: a petroleum-based route and a bio-based route, both requiring strict control of reaction conditions to ensure product purity [3][4]. - The bio-based route uses cyclopentene as a raw material, undergoing a photoxidation reaction to generate an epoxy pentenal intermediate, followed by catalytic hydrogenation under specific temperature and pressure conditions [4]. Group 2: Product Quality and Standards - The final products from both production routes must meet cosmetic ingredient standards, including purity ≥ 99%, moisture content ≤ 0.1%, and heavy metal residue ≤ 10 ppm [5]. - The bio-based 1,5-pentanediol produced by the company has a purity exceeding 99.5%, with color and moisture content well within the required limits, showcasing its compliance with or surpassing international standards [2][5]. Group 3: Market Applications - Bio-based 1,5-pentanediol is widely used in high-end cosmetics due to its excellent moisturizing and preservative properties, aligning with consumer demand for natural and green products [6]. - In the biopharmaceutical sector, 1,5-pentanediol is crucial for synthesizing various pharmaceutical intermediates, meeting the stringent requirements of the industry [6]. - The compound also plays a key role in producing high-end polyurethane and polyester materials, which are utilized in electric vehicle battery coatings and high-value apparel materials, among other applications [6].