以下文章来源于生物基科技 ，作者生物基能源与材料 关键词| HMF-FDCA-PEF进展 | 赛瑞克、FDCA、葡萄糖二酸 2026（第十一届）生物基大会暨展览 将于5月20-22日在上海举行， 赛瑞克 将继续受邀出席同期论坛「 HMF-FDCA-PEF产业论坛（第六届） 」，分享主题报告，并在同期的展览中展示最新产品 ！ 【 生物基能源与材料 】 获 悉， 近日， 赛瑞克 生物基平台化合物项目一期近日在浙江建德完成备案， 投资7亿元 、年产5000吨FDCA和50吨葡萄糖 二酸 ，预计 2027年年中投产 。 项目信息： 项目名称 ：赛瑞克生物基平台化合物葡萄糖二酸和2,5-呋喃二甲酸项目一期 建设性质 ：新建建设 地址 ：浙江省杭州市建德市经济开发区五马洲区块拟开工 生物基科技 . 生物基科技为DT新材料旗下以分享人物观点、推动全球生物基科学与技术的创新进程为核心的创新平台。 时间 ：拟开工2026年06月；拟建成时间2027年 年中 占地面积 ：60亩建设 内容 ：项目一期总投资7亿元，其中固定资产投资6亿元，新增用地60亩，年处理葡萄糖10000吨、 年产葡萄糖二酸（GA）50吨、2,5-呋喃二甲酸 ...

| 2026.05/20-22 １１ヶ ｜ １２０．７ １５００． | | --- | 【DT新材料】获悉，12月19日，芬兰造纸巨头芬欧汇川（UPM）宣布，其位于德国Leuna的生物炼厂正式启动木基化学品的商业化生产。 这座投资13亿欧元（约107亿元人民币），年产能22万吨的工厂，是欧洲最大规模的生物化学品工业投资项目，主要产品有4个：生物基乙二醇、生物基丙 二醇、木质素基功能性填料、工业糖。 UPM是全球领先的造纸巨头，2024 年营业额约 103.39亿欧元，利润（可比 EBIT）约 12.24亿欧元。 在欧洲化工项目陆续"关停"的背景下，为何UPM投资一笔超过年度利润的资金，给一个长期被造纸业视为"废料"的市场？ 一个成长中的百亿市场 木质素，这个在造纸黑液中被大量排放或烧掉的"废料"，正在成为全球生物基产业的新宠。根据市场研究机构Precedence Research数据，2024年全球木质 素市场规模为11.3亿美元，预计到2032年将达到16.2亿美元，复合年增长率为4.1%。 更值得关注的是生物基乙二醇和生物基丙二醇。根据Straits Research数据，生物基乙二醇2024年市场规模为 ...

以下文章来源于生物基科技 ，作者生物基能源与材料 生物基科技 . 生物基科技为DT新材料旗下以分享人物观点、推动全球生物基科学与技术的创新进程为核心的创新平台。 【DT新材料】 获 悉，12月19日， 芬兰造纸巨头 芬欧汇川 （UPM） 宣布，其位于 德国Leuna的生物炼厂正式启动木基化学品的商业化生产 。 这座投资 13亿欧元（约107亿元人民币） ，年产能 22万吨 的工厂，是 欧洲最大规模的生物化学品工业投资项目 ，主要产品有4个： 生物基乙二醇、 生物基丙二醇、木质素基功能性填料、工业糖 。 UPM是全球领先的造纸巨头，2024 年营业额约 103.39 亿欧元，利润（可比 EBIT）约 12.24 亿欧元。 在欧洲化工项目陆续"关停"的背景下， 为何UPM投资一笔超过年度利润的资金，给一个长期被造纸业视为"废料"的市场？ 一个成长中的百亿市场 木质素，这个在造纸黑液中被大量排放或烧掉的"废料"，正在成为全球生物基产业的新宠。 根据市场研究机构Precedence Research数据，2024年全 球木质素市场规模为11.3亿美元，预计到2032年将达到 16.2亿美元 ，复合年增长率为4.1%。 ...

Core Viewpoint - The article discusses the recent re-approval of two significant projects by Shandong Tianyi Hongda Biotechnology Co., Ltd., focusing on the production of bio-based succinic acid and 1,4-butanediol, highlighting their investment details and potential applications in various industries [2][3][4][5]. Investment and Project Details - The bio-based succinic acid project has a total investment of 50.483 million yuan, with 1.5 million yuan allocated for environmental protection, accounting for 2.97% of the total investment. The project covers an area of 223.22 acres (148,814.08 m²), with the specific project area being 152.22 acres (101,480.51 m²) [3]. - The 1,4-butanediol production project has a total investment of 19.703 million yuan, with 1.5 million yuan for environmental protection, which constitutes 7.61% of the total investment. This project occupies 71 acres (47,333.57 m²) and is located in the Changyi Chemical Industry Park in Weifang City, Shandong Province [4]. Applications of Products - Succinic acid can be utilized in the production of plastics, resins, and rubber, serving as a plasticizer, modifier, coating agent, and adhesive. It also acts as an intermediate in pharmaceuticals for synthesizing certain drugs and can be used as a food additive, flavoring agent, preservative, and acidulant [3]. Company Overview - Shandong Tianyi Hongda Biotechnology Co., Ltd. was established on March 21, 2024, with a registered capital of 10 million yuan. The company is located in the Changyi Chemical Industry Park and focuses on bioengineering and bio-based chemicals, integrating research and development, production, and sales [5].

Core Points - The "2025 (Fifth) Non-Grain Biomass High-Value Utilization Forum" will be held from November 27-29, 2025, in Hangzhou, Zhejiang, focusing on innovations and commercialization in the non-grain biomass sector [2] - The forum aims to promote large-scale applications of non-grain biomass utilization to support carbon neutrality goals [2] Event Details - The forum will feature nearly 50 presentations discussing key strategic areas such as green pretreatment of biomass, non-grain sugars, biomass-based chemicals and materials, and biomass energy including methanol, fuel ethanol, biogas, and sustainable aviation fuel (SAF) [2] - Registration and check-in will occur on November 27 from 12:00 to 20:00, with various activities scheduled throughout the event [4][9] Organizing Institutions - The forum is co-hosted by DT New Materials and the National Key Laboratory of Biomass Transportation Fuel Technology, with notable figures from various academic and research institutions involved [8][6] Agenda Highlights - The agenda includes a youth forum on non-grain biomass innovations, a SAF industry exchange meeting, and thematic forums on biomass chemicals, materials, and energy [9][30] - Keynote speakers include prominent researchers and industry leaders discussing advancements in biomass utilization and sustainable fuel technologies [23][30] Supporting Units - The event is supported by several academic institutions and associations, including Zhejiang University and various research laboratories focused on biomass materials and technologies [8][6]

Core Viewpoint - The "NFUCon 2025" forum will focus on innovations and commercialization in the non-grain biomass sector, aiming to promote large-scale applications of biomass and support carbon neutrality goals [2][3]. Group 1: Event Overview - The forum will take place from November 27-29, 2025, in Hangzhou, Zhejiang, and is co-hosted by DT New Materials and the National Key Laboratory of Bio-based Transportation Fuel Technology [2]. - The theme of the forum is "Gathering Talents from All Directions, Assisting Non-Grain Initiatives" [2]. Group 2: Organizing Institutions - The forum is organized by DT New Materials and the National Key Laboratory of Bio-based Transportation Fuel Technology, with key figures such as Zhu Jin and Li Zhenglong serving as co-chairs [3]. - Supporting institutions include Zhejiang University and various research and industry associations [4]. Group 3: Forum Agenda - The agenda includes presentations on innovative processes for producing bio-based chemicals and materials, as well as discussions on biomass energy applications [6][9]. - A special session will focus on sustainable aviation fuel (SAF), inviting over 20 industry representatives to discuss trends and technological routes [7][10]. Group 4: Technology and Innovation - The forum will showcase 50 innovative projects in biomass utilization with commercial potential, facilitating industry-academia collaboration [11]. - Key topics include the development of bio-based materials, clean and efficient biomass pretreatment technologies, and advancements in biofuel production [9][10]. Group 5: Industry Participation - Notable companies and organizations such as China National Aviation Corporation and Boeing (China) are expected to participate in discussions on SAF and its industrialization [7][10]. - The event aims to foster collaboration among government, academia, and industry to advance the bio-based economy [2][3].

Core Viewpoint - The NFUCon 2025 forum will focus on the innovative research and commercial feasibility in the non-grain biomass sector, aiming to promote large-scale applications of non-grain biomass and support carbon neutrality goals [2]. Group 1: Event Overview - The NFUCon 2025 will be held from November 27 to 29, 2025, in Hangzhou, Zhejiang, under the theme "Top Talent Gathering, Industry Symbiosis" [2]. - The forum will invite representatives from government, enterprises, and experts to discuss key strategic directions such as biomass green pretreatment, non-grain sugars, biomass-based chemicals and materials, and biomass energy [2]. Group 2: Organizing Institutions - The forum is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. and the National Key Laboratory of Biomass Transportation Fuel Technology [3]. - Key figures include Zhu Jin, Li Zhenglong, and Zhang Xinghong, who hold significant positions in relevant research institutions and laboratories [3][4][5]. Group 3: Guest Speakers - Notable speakers include Zhu Jin, who has achieved multiple industrialization results in heat-resistant polylactic acid foaming materials and other biomass materials [4]. - Li Zhenglong focuses on the conversion and utilization of low-carbon resources, particularly in renewable aviation fuel and biomass high-value utilization [5]. - Zhang Xinghong is involved in polymer synthesis research and CO2-based polycarbonate technology [6]. Group 4: Forum Agenda - The forum will feature various activities, including a youth forum on non-grain biomass, a sustainable aviation fuel industry exchange, and thematic discussions on biomass chemicals and energy [15][16]. - A technology achievement display area will be set up to showcase 50 innovative results and projects with commercial potential in biomass utilization [17]. Group 5: Laboratory Focus - The National Key Laboratory of Biomass Transportation Fuel Technology focuses on four core areas: fiber ethanol technology, bio-aviation fuel technology, CO2-based polycarbonate technology, and biofuel evaluation standards [22].

Core Viewpoint - The article discusses the advancements in the production of 1,3-propanediol (1,3-PDO) using engineered strains of Klebsiella pneumoniae, highlighting significant improvements in yield and efficiency through metabolic engineering and strain evolution [2][20][23]. Summary by Sections 1. Production Methodology - 1,3-PDO is a high-value fine chemical used in cosmetics, pharmaceuticals, and plastics, traditionally produced through chemical synthesis, which involves toxic substances and high pressure. Microbial fermentation has emerged as a more economical and environmentally friendly production method [2]. - The research team led by Professor Liu Liming achieved a production yield of 138.6 g/L of 1,3-PDO using the engineered strain FMME-51, with a conversion rate of 0.52 g/g, without the need for additional VB12 [2][20]. 2. Strain Optimization - Initial strain FMME-01 produced 67.2 g/L of 1,3-PDO but generated multiple by-products that reduced yield. Subsequent modifications led to strain FMME-14, which showed improved production performance [6]. - Further optimization of the cell membrane composition in strain FMME-38 resulted in a 62.5% increase in tolerance to high 1,3-PDO concentrations and a 41.2% reduction in cell death [9][10]. 3. Enhancements in Co-Factor Synthesis - The production process relies on VB12 and NADH. The integration of genes responsible for VB12 synthesis into the genome of strain FMME-48 resulted in a VB12 concentration of 50.8 μg/L and a 1,3-PDO yield of 118.3 g/L [14]. - The dynamic regulation of NADH levels was achieved through the construction of a biosensor-based system, enhancing the NADH/NAD⁺ ratio by 31.3% in strain FMME-51, leading to a 12.3% increase in 1,3-PDO yield [18][14]. 4. Process Optimization - The optimization of glycerol feeding rates and pH levels significantly improved the production performance of strain FMME-51, achieving a 1,3-PDO yield of 135.9 g/L at a pH of 6.8 [19]. - The final optimized strain FMME-51 demonstrated a production capacity of 122.7 g/L of 1,3-PDO using low-cost crude glycerol as a substrate, showcasing its industrial potential [20][23]. 5. Industrial Implications - The research indicates a significant advancement in the bioproduction of 1,3-PDO, achieving unprecedented yields and efficiencies while eliminating the need for expensive co-factors, thus reducing production costs [20][23]. - The ability of engineered strain FMME-51 to efficiently utilize crude glycerol highlights its potential for large-scale industrial applications in the production of high-value chemicals [23].

Core Viewpoint - Anhui Huaheng Biotechnology Co., Ltd. is planning to issue overseas shares (H shares) and list on the Hong Kong Stock Exchange to advance its global development strategy, with a current market value of approximately 8.35 billion [1] Company Overview - Huaheng Biotechnology focuses on synthetic biology technology, specializing in the R&D, production, and sales of bio-based products, and is recognized as a national torch key high-tech enterprise [1] - The company's main products include various amino acids and bio-based chemicals, which are widely used in multiple sectors such as intermediates, animal nutrition, personal care, plant nutrition, and functional food [1] - Huaheng has become one of the leading companies in the large-scale production of small-volume amino acid products through biological manufacturing [1] Market Position - The company ranks first globally in the production and sales of alanine and valine [1] - Recent strategic expansions include investments in bio-based chemicals such as 1,3-propanediol, succinic acid, and L-malic acid, alongside investments in related startups [1] Fundraising and Projects - In June 2023, Huaheng planned to raise no more than 1.689 billion to establish production bases for bio-based succinic acid and bio-based malic acid, each with an annual capacity of 50,000 tons [1] Collaborations and Innovations - In August 2023, Huaheng and Kaifeng Fund invested a total of 20 million in Ruijia Kang, focusing on non-grain bulk alcohol acids, with some products entering the pilot testing phase [2] - In March 2024, the company’s Chifeng base successfully commenced production of 50,000 tons of bio-based 1,3-propanediol and succinic acid [2] - In July 2024, Huaheng collaborated with Donghua University to establish a joint laboratory for bio-based chemical fibers, promoting the development of the PDO-PTT industrial chain [2] Industry Initiatives - In September 2024, Huaheng led the establishment of the world's first "Bio-based Polyester Textile Industry Alliance," aiming to create a complete bio-based polyester industry chain through collaboration among various stakeholders [4]

Core Viewpoint - The Ministry of Industry and Information Technology of China has officially announced the "First Batch of Iconic Products in Biological Manufacturing," which includes 36 products, marking a significant step in technological innovation and industrial upgrading in the biological manufacturing sector [1][3]. Summary by Sections Iconic Products List - The list includes 36 companies such as: - Shoulang Biotechnology - Micro元合成 - KaiLaiYing - Qinhongdao Huaheng Biotechnology - Qilu Pharmaceutical - JinSai Pharmaceutical - And others [3][5]. Product Details - Each product listed has specific applications and innovations: - **Ethanol Clostridium Protein**: Produced from industrial waste gases, beneficial for animal feed [5]. - **Alotose**: A low-calorie sweetener produced through microbial fermentation, enhancing production efficiency [5]. - **Nakiol Injection**: A CAR-T cell therapy for treating acute lymphoblastic leukemia, showing improved safety and efficacy [5]. - **Vitamin B**: Produced via fermentation, offering higher efficiency compared to traditional extraction methods [7]. - **Recombinant Human Serum Albumin**: Produced using rice cell technology, meeting clinical needs effectively [9]. Industry Significance - The announcement reflects the government's strong emphasis on the development of the biological manufacturing industry, showcasing the potential for innovation and growth in this sector [1][3]. Upcoming Events - The "SynBioCon 2025" conference will be held from August 20-22, focusing on AI in biological manufacturing, green chemistry, and future food and agriculture [11][12].