Core Viewpoint - Xiansheng Pharmaceutical (02096) reported strong mid-year performance, with significant growth in revenue and net profit driven by innovative drug sales [1] Financial Performance - The company achieved a revenue of 3.585 billion yuan, representing a year-on-year increase of 15.1% [1] - Adjusted net profit reached 651 million yuan, up 21.1% year-on-year [1] Innovative Drug Development - Xiansheng Pharmaceutical has launched ten innovative drugs, with innovative drug revenue of 2.776 billion yuan, a 26% increase year-on-year [1] - The proportion of innovative drug revenue in total revenue exceeded 75% for the first time, reaching 77.4% [1] - Two innovative drugs are expected to be approved for market launch in the first half of 2025, and two candidate drugs are in the NDA review stage [1] Market Expectations - CICC believes that the company's mid-year performance exceeded market expectations, primarily driven by the innovative drug business [1] - The revenue from innovative drugs in the first half of 2025 is projected to reach 2.776 billion yuan, a 26% increase, with the revenue share rising from 74.3% in 2024 to 77.4% [1] - The company anticipates that the innovative drug "Kewiko" (Daliresib) may officially launch in the second half of 2025 [1] - Three products (Suvorexant, Daliresib, and the sublingual tablet) have been included in the recent commercial insurance catalog, which is expected to further boost innovative drug revenue [1]

Core Viewpoint - Xiansheng Pharmaceutical (02096) reported strong growth in its first half of 2025, driven by its innovative drug business, with revenue and adjusted net profit increasing by 15% and 21% year-on-year respectively [1][2] Group 1: Financial Performance - For 1H25, Xiansheng Pharmaceutical achieved a revenue of 27.76 billion yuan, reflecting a year-on-year increase of 15% [1][2] - The adjusted net profit for the same period rose by 21%, aligning with market expectations [1] - The innovative drug revenue grew by 26%, contributing to 77.4% of total revenue, an increase of 6.6 percentage points year-on-year [1][2] Group 2: Research and Development - The company invested over 1 billion yuan in R&D during 1H25, accounting for nearly 30% of total revenue [1] - Significant innovative research outcomes include the launch of Daliresp and Suweisita monoclonal antibody [1] - The company completed two business development transactions with AbbVie and NextCure, focusing on GPRC5D/BCMA/CD3 tri-antibody and CDH6ADC, with the former expected to enter Phase I trials in 2026 [1] Group 3: Market Outlook - The rapid growth of innovative drugs such as Kexaira and Xianbi sublingual tablets is anticipated to continue, with Kexaira expected to officially launch in the second half of 2025 [2] - Three products, including Suweisita monoclonal antibody, Daliresp, and Xianbi sublingual tablets, have been included in the recent commercial insurance directory, which is expected to further boost innovative drug revenue [2]

Core Viewpoint - The company reported strong performance in 1H25, exceeding market expectations with significant growth in revenue and net profit driven by its innovative drug business [1][2]. Financial Performance - Revenue for 1H25 reached 3.585 billion yuan, a year-on-year increase of 15.1% [1] - Net profit attributable to shareholders was 604 million yuan, up 32.2% year-on-year, while adjusted net profit was 651 million yuan, reflecting a 21.1% increase [1] - The gross margin improved to 80.7%, an increase of 1.6 percentage points year-on-year [2] - Adjusted net profit margin stood at 18.2%, showing a year-on-year increase of 0.9 percentage points [2] Business Development - The innovative drug business showed strong commercialization progress, with revenue reaching 2.776 billion yuan in 1H25, a 26.0% increase year-on-year, and its revenue share rising from 74.3% in 2024 to 77.4% [1] - Key products such as Koseira and Xianbi sublingual tablets are experiencing rapid growth, with expectations for the launch of Koweike (Daliresheng) in 2H25 [1] - The company’s revenue in the neuroscience segment was 1.249 billion yuan, up 37.3% year-on-year, while oncology revenue reached 874 million yuan, a 41.1% increase [1] Research and Development - The company maintained a research and development investment rate of 28.7%, an increase of 9.0 percentage points year-on-year, indicating a commitment to innovation [2] - Two products were authorized for external licensing, and two products received approval for market launch [2] Profit Forecast and Valuation - The company raised its core net profit forecasts for 2025 and 2026 by 6% and 10% to 1.252 billion yuan and 1.427 billion yuan, respectively [2] - The current stock price corresponds to 23.8 times and 20.0 times the adjusted price-to-earnings ratio for 2025 and 2026 [2] - The target price was increased by 32.8% to 17.00 HKD, implying a potential upside of 33.1% [2]

Group 1 - The core viewpoint of the article emphasizes the solid position of the company as a leading player in the neuro-specialty pharmaceutical sector, with significant growth potential from innovative drugs [1][6][12] - The approval of the sublingual formulation of Xianbixin is expected to enhance treatment adherence among acute stroke patients, potentially making it a key drug for improving stroke prognosis [1][20][22] - The company has successfully launched multiple innovative drugs, with eight already approved and several included in the national medical insurance directory, indicating a strong growth trajectory [9][12][59] Group 2 - The new generation of DORA insomnia drugs is rapidly gaining market traction, with Dalirelix expected to be launched in China soon, following successful approvals in other regions [2][55][51] - The sales of DORA insomnia drugs have shown impressive growth, with Suvorexant achieving sales of $330 million in 2020 and Lemborexant surpassing $260 million in 2023 [2][51] - The company has established a strong research and development framework, with significant investments leading to a rapid increase in innovative drug revenue, which has grown at a CAGR of 33.8% from 2017 to 2023 [12][15][57] Group 3 - The oncology sector is entering a phase of intensive product launches, with several innovative cancer drugs recently approved and included in the national medical insurance directory, indicating potential for significant market expansion [3][32][58] - The company’s innovative drugs in oncology, such as Envidat and Koseira, are expected to drive future revenue growth, with projected revenues of 15.16 billion, 17.84 billion, and 22.06 billion yuan from 2024 to 2026 [58][59] - The company is focusing on differentiated pipeline strategies, particularly in the development of TCE tri-antibodies like SIM0500, which are currently undergoing clinical trials in the US and China [4][40][36] Group 4 - The company has a robust pipeline of innovative drugs, with a focus on collaborative development across various therapeutic areas, including neurology and oncology [33][36] - The company’s R&D investment has significantly increased, with a CAGR of 39.5% from 2017 to 2023, enhancing its capacity for innovation and long-term growth [15][57] - The company’s innovative drug revenue is projected to continue growing, with expectations of reaching 67.76 billion yuan in 2024, reflecting a year-on-year growth of 3% [59][60]