在国际化布局上，继今年上半年恩杂卢胺片与达格列净二甲双胍缓释片获得美国FDA暂时批准后，宣泰 医药产品梯队不断拓展：今年10月，枸橼酸托法替布缓释片（11mg）获得美国FDA正式批准，西格列 汀二甲双胍缓释片获得美国FDA暂时批准。 在国内市场，宣泰医药同样取得了积极进展。西格列汀二甲双胍缓释片50/500mg新规格获得国家药品 监督管理局（NMPA）批准，进一步丰富了公司在糖尿病领域的产品组合，增强了针对不同临床需求的 覆盖能力。此外，奥帕利片成功中选第十一批全国药品集中采购，西格列汀二甲双胍缓释片（II）原价 续约纳入国家医保目录，将进一步推动相关产品的市场推广、提升销售规模，对公司的长期经营发展具 有积极影响。 宣泰医药表示，此次公布激励计划，一方面向市场传递公司对未来长远发展的信心，另一方面能调动核 心员工的积极性，吸引、保留和激励优秀管理者、核心技术骨干员工，支持公司战略实现和长期可持续 发展，充分释放公司整体经营活力。（厉平） 12月25日晚间，宣泰医药(688247)公告《2025年限制性股票激励计划（草案）》，拟采用第二类限制性 股票的方式，向激励对象授予不超过623.00万股，约占公司股本总 ...

证券日报网讯 12月4日晚间，赛升药业发布公告称，子公司北京赛而生物药业有限公司近日收到了国家 药品监督管理局下发的达格列净二甲双胍缓释片境内生产药品注册上市许可申请的《受理通知书》。 （文章来源：证券日报） ...

Group 1 - China Pacific Insurance has received approval from the financial regulatory authority for Wang Yuhua to serve as a director [1] - Shanghai Bank announced that the regulatory authority has approved Chen Lei's qualification as vice president [2] - Shanghai HuGong has decided to terminate the "Aerospace Equipment Manufacturing Base" fundraising project due to significant changes in project feasibility [3] Group 2 - Dongwang Times plans to reduce its stake by up to 1.20% through share sales [4] - Zhinancun intends to increase its capital by 100 million yuan in its wholly-owned subsidiary, Maigao Securities [5] - Jinxinnong reported a sales revenue of 115 million yuan from pig sales in November [6] Group 3 - Tiantan Biological has completed the Phase III clinical trial of its human prothrombin complex, showing good efficacy and safety for hemophilia B patients [7] - Beijete's subsidiary has signed a framework agreement for equity acquisition to gain control of Yunnan Wenye Nonferrous Metals [8] - Zhongsheng Pharmaceutical's RAY1225 injection has received approval for a new clinical trial indication for treating metabolic-associated fatty liver disease [9] Group 4 - Enhua Pharmaceutical's hydrochloride sulpiride tablets have passed the consistency evaluation for generic drugs [10] - Shenkong Co. plans to invest 60 million yuan in a semiconductor industry fund [11] - Lianhuan Pharmaceutical's subsidiary has received approval for its drug to pass the consistency evaluation for generic drugs [12] Group 5 - Dazhong Transportation has received approval to issue debt financing tools totaling 4.5 billion yuan [13] - Jintian Titanium Industry plans to invest 50 million yuan in an industry merger and acquisition fund [14] - Changchun Gas has committed over 1.7 billion yuan to gas facility upgrades [15] Group 6 - Laimei Pharmaceutical's innovative anti-cancer drug "Nano Carbon Iron" has received approval for clinical trials [16] - Longquan Co. has signed supply contracts worth approximately 50.76 million yuan for nuclear power components [17] - Igor plans to distribute a cash dividend of 1 yuan per 10 shares [18] Group 7 - Xingfa Group's subsidiary has signed a processing agreement for 80,000 tons of lithium iron phosphate [20] - Yunjigroup's director Wang Wanfeng has resigned for personal reasons [21] - Saiseng Pharmaceutical's application for the listing of a new drug has been accepted by the regulatory authority [22] Group 8 - Xinhua Medical has obtained registration certificates for two new medical devices [23] - Chaoying Electronics plans to invest 100 million USD in its Thai subsidiary for an AI circuit board expansion project [24] - Suzhou Planning's application to acquire 100% of Dongjin Aviation has been accepted by the Shenzhen Stock Exchange [25]

人民财讯12月4日电，赛升药业（300485）12月4日公告，子公司赛而生物近日收到国家药监局下发的达 格列净二甲双胍缓释片境内生产药品注册上市许可申请的受理通知书。 SGLT-2抑制药达格列净和盐酸二甲双胍的复方片剂由英国阿斯利康制药公司研发，于2014年FDA批准 上市。2023年6月，该品种在我国批准上市。SGLT-2抑制剂是通过非胰岛素依赖机制发挥作用，通过减 少葡萄糖在肾脏的重吸，从尿中直接排糖来降低血糖，SGLT-2联用二甲双胍表现了更好的降糖效果和 更低的副作用。 ...

SGLT-2抑制药达格列净和盐酸二甲双胍的复方片剂由英国阿斯利康制药公司研发，于2014年FDA批准 上市。2023年6月，该品种在我国批准上市。SGLT-2抑制剂是通过非胰岛素依赖机制发挥作用，通过减 少葡萄糖在肾脏的重吸，从尿中直接排糖来降低血糖，SGLT-2联用二甲双胍表现了更好的降糖效果和 更低的副作用。 赛升药业（300485）(300485.SZ)发布公告，公司子公司北京赛而生物药业有限公司(以下简称"赛而生 物")近日收到了国家药品监督管理局下发的达格列净二甲双胍缓释片境内生产药品注册上市许可申请的 《受理通知书》。 ...

智通财经APP讯，赛升药业(300485.SZ)发布公告，公司子公司北京赛而生物药业有限公司(以下简称"赛 而生物")近日收到了国家药品监督管理局下发的达格列净二甲双胍缓释片境内生产药品注册上市许可申 请的《受理通知书》。 SGLT-2抑制药达格列净和盐酸二甲双胍的复方片剂由英国阿斯利康制药公司研发，于2014年FDA批准 上市。2023年6月，该品种在我国批准上市。SGLT-2 抑制剂是通过非胰岛素依赖机制发挥作用，通过减 少葡萄糖在肾脏的重吸，从尿中直接排糖来降低血糖，SGLT-2联用二甲双胍表现了更好的降糖效果和 更低的副作用。 ...

赛升药业公告称，其子公司赛而生物近日收到国家药监局下发的达格列净二甲双胍缓释片境内生产药品 注册上市许可申请的《受理通知书》，涉及（Ⅰ）（Ⅱ）（Ⅲ）（Ⅳ）四个规格。该复方片剂由阿斯利 康研发，2014年在美国获批上市，2023年6月在我国获批。此次申请获受理意味着该品种进入注册审评 阶段，对公司近期业绩无重大影响，若顺利通过审评，将丰富赛而生物产品管线，不过药品注册批准时 间和结果不确定。 ...

格隆汇12月4日丨赛升药业(300485.SZ)公布，子公司北京赛而生物药业有限公司近日收到了国家药品监 督管理局下发的达格列净二甲双胍缓释片境内生产药品注册上市许可申请的《受理通知书》。SGLT-2 抑制药达格列净和盐酸二甲双胍的复方片剂由英国阿斯利康制药公司研发，于2014年FDA批准上市。 2023年6月，该品种在我国批准上市。SGLT-2抑制剂是通过非胰岛素依赖机制发挥作用，通过减少葡萄 糖在肾脏的重吸，从尿中直接排糖来降低血糖，SGLT-2联用二甲双胍表现了更好的降糖效果和更低的 副作用。 ...

Core Viewpoint - Company received acceptance notification for drug registration applications for Dapagliflozin Metformin Extended-Release Tablets (I, II, III) from the National Medical Products Administration [1] Company Summary - Dapagliflozin Metformin Extended-Release Tablets are a fixed-dose combination formulation consisting of SGLT2 inhibitor Dapagliflozin and the biguanide drug Metformin [1] - The combination aims to provide comprehensive and effective blood glucose control for adult patients with type 2 diabetes [1] Industry Summary - The product is co-developed by Bristol-Myers Squibb Company and AstraZeneca AB [1] - As of the announcement date, eight domestic companies have received approval for similar products, excluding imported ones [1]

据悉，达格列净二甲双胍缓释片是一种固定剂量复方制剂，由钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂 达格列净和双胍类药物盐酸二甲双胍组成，结合了两种作用机制不同但相互协同作用的降糖药物。达格 列净通过促进尿糖排泄来降低血糖，而二甲双胍则主要通过抑制肝糖输出和改善胰岛素敏感性来发挥作 用。这种联合用药方式旨在为2型糖尿病成人患者提供更全面、更有效的血糖控制。该品种为百时美施 贵宝(Bristol-Myers Squibb Company，BMS)和阿斯利康(AstraZeneca AB，AZ)共同开发的缓释复方制 剂。截至本公告日，除进口产品外，国内有8家企业相同产品获批上市。 立方制药（003020）(003020.SZ)发布公告，近日，公司收到国家药品监督管理局下发的达格列净二甲 双胍缓释片(I)、达格列净二甲双胍缓释片(II)及达格列净二甲双胍缓释片(III)药品注册上市许可申请《受 理通知书》。 ...