海利生物（603718）9月15日晚间公告，将瑞盛生物55%股权的收购价格由9.35亿元下调至5.36亿元，业 绩承诺相应调整。海利生物方面表示，在瑞盛生物出现经营业绩下滑的背景下，此举使得公司降低了投 资成本，控制了投资风险，有利于维护公司及全体股东的利益。 公告显示，海利生物收购瑞盛生物55%股权的价格由9.35亿元调整为5.36亿元，同时2025年度和2026年 度的扣非净利润承诺数分别调整为5000万元和5800万元。 这笔收购在去年10月份已经完成，瑞盛生物2024年度的净利润承诺数也已达成。在本次调整后，交易对 手将返还本次调整后的交易价格差额3.99亿元，同时预计也可以调减原收购瑞盛生物时形成的商誉。本 次调整事项尚需提交公司股东会审议。 同时，瑞盛生物原适用的税收优惠政策也出现收紧。瑞盛生物的主营产品以往可申请办理一般纳税人按 3%简易征收增值税，但目前已按税务要求改为一般计税方式即按13%的税率征收增值税。 行业整体处于"价格战"的环境中，作为行业龙头企业，瑞盛生物仍存在一定优势。半年报显示，一方 面，随着新基地的启用，发货量的增加推动瑞盛生物骨粉、骨膜综合市占率相比去年半年度提高了约 6% ...

Core Viewpoint - Shanghai Haili Biological Technology Co., Ltd. announced that its subsidiary, Shaanxi Ruisheng Biotechnology Co., Ltd., has received a notice of acceptance from the National Medical Products Administration for the registration application of three types of medical devices, specifically "bone repair materials" [1] Group 1: Product Details - The products are classified as Class III medical devices, suitable for filling and repairing maxillofacial bone defects and alveolar bone defects (or insufficient bone volume) [1] - The application includes structured products such as block and column types, which can better match the bone defect areas compared to the existing granular bone repair materials, effectively reducing bone powder displacement and improving surgical efficiency and osteogenic effects [1] Group 2: Regulatory Process - The registration application is currently in the review and approval stage, with a statutory administrative approval period of 20 working days, which can be extended by an additional 10 working days under special circumstances [1] Group 3: Market Implications - If the product is successfully approved for market launch, it will enrich Haili Biological's product line in the field of oral bone defect repair [1] - The company notes that the product is still in the acceptance stage, and its impact on future performance remains uncertain [1]

格隆汇9月1日丨海利生物(603718.SH)公布，控股子公司陕西瑞盛生物科技有限公司（简称"瑞盛生 物"）于近日收到国家药品监督管理局下发的医疗器械注册申请受理通知信息，产品名称：骨修复材 料。本产品骨修复材料，根据《医疗器械分类规则》（局令第15号）、《医疗器械分类目录》（2017年 第104号公告），本产品为Ⅲ类医疗器械，属于17口腔科器械，一级产品类别为"17-08口腔植入及组织 重建材料"，二级产品类别为"17-08-06骨填充及修复材料"，产品分类编码为17-08-06。该产品获批上市 后可在口腔骨缺损修复领域丰富瑞盛生物的产品线。 ...

Core Viewpoint - The announcement indicates that the application for the registration of bone repair materials by Shaanxi Ruisheng Biotechnology Co., Ltd. has been accepted by the National Medical Products Administration, which is a significant step for the company in expanding its product line in the dental field [1] Group 1 - The bone repair material is designed for filling and repairing maxillofacial bone defects and alveolar bone deficiencies, making it a critical material for oral surgery [1] - The new product will supplement the existing bone repair materials offered by Ruisheng Biotechnology, thereby enriching its product portfolio [1] - Currently, the product is in the acceptance stage, and it is expected that there will be no definitive impact on the company's existing business and operating performance [1]

Core Viewpoint - Zhenghai Biological is at a crossroads of transformation as its marketing expenses surged by 39%, yet it failed to achieve revenue growth, with a significant decline in net profit and core product revenues [4][5] Financial Performance - The company reported a 5.14% year-on-year decline in revenue to 187 million yuan, while net profit dropped by 45.97% to 46.49 million yuan, and non-recurring net profit fell by 46.77% to 40.28 million yuan [4][6] - The main reasons for the profit decline include a nearly 20% drop in oral repair membrane revenue, increased cost pressures, and changes in the external environment [4][6] Product Performance - The sales revenue of the brain membrane series products increased by 5.88% to 80.27 million yuan, becoming a rare highlight in the report, attributed to successful bids in multiple provincial alliances [6] - Conversely, the oral repair membrane business saw a revenue decline of 19.38% to 77.12 million yuan, with a decrease in gross margin by 1.63 percentage points to 85.98% [6][7] - The decline in oral repair membrane revenue is attributed to weak market demand, intensified competition, and continuous price reductions [6][7] Tax and Regulatory Impact - Starting January 1, 2025, the VAT on key raw materials for Zhenghai Biological's main products will increase from a simplified rate of 3% to a general rate of 13%, significantly eroding profit margins [7] Structural Issues - The company's revenue structure is heavily reliant on two main products, which account for over 80% of total revenue, making it vulnerable to market fluctuations [6][7] Marketing and Sales Strategy - In response to declining performance, the company increased its sales expenses to 71.18 million yuan, a 38.87% increase, primarily for market promotion and commercial support [8] - The sales expense ratio rose from 25.88% to 37.90%, while net profit margin decreased from 43.45% to 24.75%, indicating a mismatch between marketing investment and revenue generation [8][9] New Product Development - The company is pinning hopes on new products like active biological bone, which has not yet generated significant sales despite being registered for nearly three years [9][10] - Other in-development products are progressing slowly, with potential revenue contributions expected in 2-3 years, which may not address immediate financial pressures [10] International Expansion - The company is exploring international markets, which present significant potential but require higher standards for product quality, certification, and marketing capabilities [10]

Core Viewpoint - Zhenghai Biological has experienced significant shareholder reductions despite its ongoing growth and strong financial performance, raising concerns about market confidence and future stability [1][4][8]. Shareholder Reduction - The controlling shareholder, Mi Bohai, has reduced his stake by 5% from August 5 to February 3, resulting in a decrease from 42.53% to 37.53% [7]. - Longwood, the second-largest shareholder, has also been reducing its holdings, with its stake dropping to 9.27% [7]. - Together, the two major shareholders have cashed out approximately 5.77 billion yuan, with Mi Bohai realizing about 3.70 billion yuan and Longwood about 2.07 billion yuan [7][8]. Financial Performance - Zhenghai Biological has shown consistent revenue and net profit growth since 2013, with a projected annual revenue of 3.38 billion yuan and a net profit of 1.31 billion yuan for 2020, reflecting a growth rate of around 20% [2]. - The company reported revenue of 216 million yuan and net profit of 95 million yuan for the first three quarters of 2020, marking year-on-year increases of 7.39% and 19.74%, respectively [1][2]. Business Model and Product Offering - Zhenghai Biological specializes in the research, development, production, and sales of biological regenerative materials, including oral and skin repair membranes, and bone repair materials [2]. - The company maintains a high gross margin exceeding 90% since 2012, attributed to its advanced technology [2][3]. Market Challenges - The company faced unprecedented challenges during the COVID-19 pandemic, particularly in its core business areas such as oral and neurosurgery, which were significantly impacted [2].

最新一期业绩显示，2025年一季报，公司实现营业收入9741.58万元，同比8.68%；净利润2662.67万 元，同比-34.06%，销售毛利率80.96%。 序号股票简称PE(TTM)PE(静)市净率总市值(元)13正海生物32.2828.984.2639.02亿行业平均 53.5248.844.67111.58亿行业中值37.1437.112.5651.72亿1九安医疗10.9411.060.86184.59亿2英科医疗 12.7713.771.14201.84亿3新华医疗15.2014.091.2497.43亿4奥美医疗15.9515.631.6457.63亿5山东药玻 15.9516.001.83150.91亿6振德医疗16.0515.131.0258.27亿7康德莱16.5816.591.3735.73亿8九强生物 17.0215.832.0984.31亿9奥泰生物17.6018.561.4256.13亿10维力医疗17.8218.532.0940.65亿11三鑫医疗 19.1519.163.1543.57亿12安图生物19.3418.462.48220.51亿 资金流向方面，7月23日，正海生物 ...

Company Overview - Zhenghai Biological's closing price on July 8 was 20.85 yuan, up 1.21%, with a rolling PE ratio of 31.05, marking a new low in 58 days, and a total market capitalization of 3.753 billion yuan [1] - The company ranks 67th in the medical device industry, which has an average PE ratio of 51.58 and a median of 37.46 [1] Shareholder Information - As of March 31, 2025, Zhenghai Biological had 16,966 shareholders, a decrease of 193 from the previous count, with an average holding value of 352,800 yuan and an average holding quantity of 27,600 shares [1] Business Focus - Zhenghai Biological specializes in the research, production, and sales of bio-regenerative materials, with key products including oral repair membranes, absorbable dura mater patches, bone repair materials, skin repair membranes, surgical packing sponges, self-etching adhesives, active biological bone, dura mater patches, phosphoric acid etchants, and dental pit and fissure sealants [1] Industry Recognition - The company was included in the 2023 list of leading new material enterprises in Shandong Province, recognized as one of the top 50 new material enterprises [1] Financial Performance - In the first quarter of 2025, Zhenghai Biological reported revenue of 97.42 million yuan, a year-on-year increase of 8.68%, and a net profit of 26.63 million yuan, a year-on-year decrease of 34.06%, with a gross profit margin of 80.96% [1]

Group 1 - The core viewpoint of the articles highlights the performance and valuation of Zhenghai Biological, which has a current PE ratio of 31.02, significantly lower than the industry average of 50.64 [1][2] - Zhenghai Biological's market capitalization stands at 3.749 billion yuan, ranking 68th in the medical device industry based on PE ratio [1][2] - The company has been recognized as one of the top 50 new material leading enterprises in Shandong Province for 2023, indicating its strong position in the industry [1] Group 2 - As of the first quarter of 2025, eight institutions hold shares in Zhenghai Biological, with a total holding of 19.6518 million shares valued at 442 million yuan [1] - The latest financial report shows that Zhenghai Biological achieved a revenue of 97.4158 million yuan, representing a year-on-year increase of 8.68%, while net profit decreased by 34.06% to 26.6267 million yuan [1] - The company's gross profit margin is reported at 80.96%, indicating a strong profitability despite the decline in net profit [1]

Core Viewpoint - Zhenghai Biological's stock closed at 20.14 yuan, with a PE ratio of 29.99, marking a 15-day low, and a total market capitalization of 3.625 billion yuan [1] Company Summary - Zhenghai Biological focuses on the research, production, and sales of biological regenerative materials, with key products including oral repair membranes, absorbable dura mater patches, bone repair materials, skin repair membranes, surgical packing sponges, self-etching adhesives, active biological bone, dura mater patches, phosphoric acid etchants, and dental sealants [1] - The company was recognized as one of the top 50 new material leading enterprises in Shandong Province for 2023 [1] Financial Performance - For Q1 2025, the company reported revenue of 97.42 million yuan, a year-on-year increase of 8.68%, while net profit was 26.63 million yuan, reflecting a year-on-year decrease of 34.06%, with a gross profit margin of 80.96% [1] Industry Summary - The average PE ratio for the medical device industry is 49.20, with a median of 36.56, placing Zhenghai Biological at the 67th position in the industry ranking [2]