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东吴证券晨会纪要-20250917
Soochow Securities· 2025-09-17 01:24
Macro Strategy - Trump's intervention in the independence of the Federal Reserve is expected to occur through three main avenues: 1) appointing a Fed chair who is loyal to him, anticipated to be nominated in November and take office in May next year; 2) restructuring the Fed Board to eliminate dissenting members and install loyalists; 3) influencing the appointment of regional Fed presidents whose terms expire in February [1][20]. - With the new Fed chair's appointment, it is projected that the Fed will have a more significant influence on monetary policy, potentially leading to a greater than expected rate cut in 2026, with policy rates possibly falling below the neutral level of 3% [1][20]. Economic Data Analysis - In August, both domestic and external demand weakened, with supply adjustments lagging behind demand, reinforcing a short-term scenario of strong supply and weak demand. Specifically, investment has shown negative growth for two consecutive months, and retail sales growth has been declining since May [2][21]. - The divergence between supply and demand is expected to yield three outcomes: 1) GDP growth will align more closely with supply data, with Q3 GDP growth projected around 5%; 2) the current supply exceeding demand may increase price pressures, necessitating stronger policy support for price recovery; 3) if demand does not strengthen, supply will likely follow suit, leading to greater pressure on Q4 GDP compared to Q3 [2][21]. Industry Insights - The gaming industry in H1 2025 has shown strong performance, driven by innovative categories such as "micro-horror search and escape" and "overseas SLG," which have positively impacted the performance and valuation of corresponding companies [15]. - In the shipbuilding sector, new ship price indices remain high, and the merger of major shipbuilding companies is nearing completion, suggesting a favorable outlook for companies like China Shipbuilding [15]. - The environmental sector is seeing advancements in pricing mechanisms for renewable energy, particularly in waste-to-energy projects, which could enhance the economic viability of green electricity supply [17][18].
【私募调研记录】保银投资调研博瑞医药
Zheng Quan Zhi Xing· 2025-09-02 00:09
Group 1 - The core viewpoint of the news is that the company BoRui Pharmaceutical is advancing its weight loss drug candidates BGM0504 and BGM1812, with IND applications submitted in both the US and China, and BGM0504's Phase I clinical trial approved by the FDA [1] - BGM0504 tablet for weight loss has received IND approval in the US and China, with the first dose group about to start administration [1] - BGM1812 injection for weight loss has also submitted IND applications in both countries, while the oral tablet is in preclinical research [1] Group 2 - The company is developing multiple formulations based on GLP-1/GIP dual targets and mylin-like molecules to meet the needs of different weight loss populations [1] - BGM0504 injection has completed US bridging clinical trials and is preparing for Phase III trials, with domestic collaboration with China Resources Sanjiu for R&D and commercialization [1] - The oral formulation of BGM1812 aims for efficient transmembrane delivery and rapid absorption, with advantages pending clinical pharmacokinetic data verification [1] Group 3 - BGM2101 combines BGM0504 with weekly insulin for diabetes treatment, while BGM2102 is a dual-drug combination exploring significant weight loss or low-dose safety, currently in preclinical stages [1] - The company is focusing on new targets such as Myostatin and MC4R, planning to develop long-acting formulations in conjunction with GLP-1 drugs [1] - The oral technology platform is collaborating with Aoli Bio to optimize multi-stage delivery efficiency for the development of BGM0504 and BGM1812 oral tablets [1]